scholarly journals Growth and Developmental Status of Children with Congenital Heart Disease

2014 ◽  
Vol 40 (2) ◽  
pp. 54-57 ◽  
Author(s):  
AHm Nasiruzzaman ◽  
MZ Hussain ◽  
MA Baki ◽  
MA Tayeb ◽  
MN Mollah
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Social Impairment ◽  
Study Patient ◽  
Fine Motor ◽  
Cyanotic Heart Disease ◽  
Developmental Status ◽  
Gross Motor ◽  
Motor Delay

Cardiac malformations ore responsible for malnutrition, which may range from mild under nutrition to severe failure to thrive (FTT). Developmental delay was also associated with congenital heart disease. The aim of the study was to evaluate the nutritional status and developmental status of children with congenital heart disease. This cross sectional study was done in the department of Paediatrics, BSMMU and Dhaka Shishu Hospital from March'08 to February'09. Children, age 1 month to 6 years with congenital heart disease confirmed by echocardiogram (both cyanotic and acyanotic heart disease) were included in this study. Total 50 children included in this study. Mean age of study patient was 3.04 (±2.01SD) years. Ventricular septal defects were found as leading number (36%). Tetralogy of Fallot was found in 26% cases. According to WHO standard 38% children from acyanotic and 16%/rom cyanotic heart disease were severely stunted. Ten percent children from acyanotic and 04% from cyanotic heart disease were severely wasted. Gross motor and fine motor delay was present in 60% and 54% of children. Forty four percent children had speech delay and social impairment was present in 32% children. Severe stunting was more common than wasting in this study. Gross motor and fine motor delay was found the main developmental problem. DOI: http://dx.doi.org/10.3329/bmj.v40i2.18512 Bangladesh Medical Journal 2011 Vol.40(2): 54-57

Risk Factors for Gross Motor Dysfunction in Infants With Congenital Heart Disease

2011 ◽  
Vol 24 (3) ◽  
pp. 246-258 ◽  
Author(s):  
Suzanne H. Long ◽  
Bev J. Eldridge ◽  
Mary P. Galea ◽  
Susan R. Harris
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Motor Dysfunction ◽  
Gross Motor

Superior Performance in Prone in Infants With Congenital Heart Disease Predicts an Earlier Onset of Walking

2018 ◽  
Vol 33 (14) ◽  
pp. 894-900 ◽  
Author(s):  
Lynn Dagenais ◽  
Manuela Materassi ◽  
Beatrice Desnous ◽  
Marie-Claude Vinay ◽  
Amélie Doussau ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Motor Development ◽  
Congenital Heart ◽  
Predictive Ability ◽  
Female Gender ◽  
Superior Performance ◽  
Motor Delay ◽  
Limited Experience ◽  
Hospital Stays

Infants with congenital heart disease are at risk of impaired neurodevelopment, which frequently manifests as motor delay during their first years of life. This delay is multifactorial in origin and environmental factors, such as a limited experience in prone, may play a role. In this study, we evaluated the motor development of a prospective cohort of 71 infants (37 males) with congenital heart disease at 4 months of age using the Alberta Infant Motor Scales (AIMS). We used regression analyses to determine whether the 4-month AIMS scores predict the ability to walk by 18 months. The influence of demographic and clinical variables was also assessed. Fifty-one infants (71.8%) were able to maintain the prone prop position (AIMS score of ≥3 in prone) at 4 months. Of those, 47 (92.2%) were able to walk by 18 months compared to only 12/20 (60%) of those who did not maintain the position. Higher AIMS scores were predictive of a greater likelihood of walking by 18 months ( P < .001), with the scores in prone having a higher predictive ability compared to those in other positions (Exp(B) 15.2 vs 4.0). Shorter hospital stays and female gender were also associated with an earlier onset of walking. In conclusion, our study demonstrates that early ventral performance in infants with congenital heart disease impacts the age of acquisition of walking and could be used to guide referral to rehabilitation.

scholarly journals COMPARISON OF SERUM VITAMIN A LEVELS BETWEEN NEONATES WITH CONGENITAL HEART DISEASE AND CONTROLS

2018 ◽  
Vol 11 (10) ◽  
pp. 130
Author(s):  
Saeed Abtahi ◽  
Zahra Mostafavian ◽  
Babak Behnam ◽  
Zahra Abbasi Shaye
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Vitamin A ◽  
Congenital Heart ◽  
Laboratory Data ◽  
Serum Vitamin ◽  
Analysis Of Covariance ◽  
Cyanotic Heart Disease ◽  
Significant Difference ◽  
The Mean

Objective: Prevention of congenital heart disease (CHD) has been hampered by a lack of information about the known modifiable risk factors for abnormalities in cardiac development. Vitamin A plays an important role in the periods of rapid cellular growth and differentiation, especially during pregnancy. Assuming a link between Vitamin A levels and congenital malformations, hypothetical different levels of Vitamin A were evaluated in neonates with and without CHD, in this study.Methods: In a case–control study that was conducted in 2015 in Mashhad/Iran, serum levels of Vitamin A in 30 neonates with CHD were compared to 30 healthy controls. The cases were diagnosed by echocardiography and recruited by convenience sampling. Demographic and laboratory data including age, sex, and serum Vitamin A level in each group were collected. Data analysis was done in SPSS V 20 software, and descriptive statistics, t-test, and analysis of covariance were used.Results: The mean age in cases was 11±3.4 days and in controls was 12.5±4.8 days. A total of 18 patients (60%) were male. In CHD patients, 10 cases (33.3%) had cyanotic heart disease, and 20 cases (66.7%) had non-cyanotic heart disease. The mean serum Vitamin A values in subjects (11.54±9.56 μg/dL) and controls (21.84±14.3 μg/dL) were significantly different, (p<0.05) and in case group was lower than the normal range.Conclusion: There was a significant difference in serum Vitamin A values in subjects and controls. Therefore, awareness of people about the importance of this vitamin in preventing CHD in children seems necessary.

scholarly journals Serum Metabolomics Profiling to Identify Novel Biomarkers for Cyanotic Heart Disease

2021 ◽  
Vol 14 (1) ◽  
pp. 81-94
Author(s):  
Suman Vimal ◽  
Surendra Kumar Agarwal ◽  
Surabhi Yadav ◽  
Gauranga Majumdar ◽  
Balraj Mittal ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Metabolic Profiles ◽  
Cyanotic Heart Disease ◽  
Metabolic Disturbances ◽  
Multivariate Statistical ◽  
Delay In Diagnosis ◽  
Novel Biomarkers

Congenital heart disease (CHD) is one of the most important causes of the death of children and young adults. Most of the patients do not survive past their teen years. This occurs either due to delay in diagnosis or no diagnosis at all. In recent times, several studies have shown the importance of biomarkers in the prediction of such defects. These biomarkers give the real time snapshot of the on going processes inside the cells and can significantly support the diagnosis of CHD. The present experiment was designed as an observational single centre pilot study to identify and establish the diagnostic metabolic signatures associated with the congenital heart diseases. Metabolic profiles of sera collected from 35 cyanotic congenital heart disease patients and 15 controls were obtained using high-resolution 1D 1H CPMG and NMR spectra. The metabolic profiles were compared using multivariate statistical analysis to identify the disease specific metabolic disturbances associated with cyanotic heart disease. The results show perturbation in several metabolites in cyanotic CHD patients versus controls. The discriminatory metabolites were further analysedwith area under receiver operating characteristic (AUROC) curve and identified five metabolic entities (i.e.valine, glucose, glutamine, creatinineand PUFA) which could differentiate cyanotic CHDs from controls with higher specificity.In conclusion, untargeted metabolic approach proved to be helpful in identifying and differentiating disease causing metabolites in cyanotic cases from controls.

CYANOTIC HEART DISEASE AND PSYCHOLOGICAL DEVELOPMENT

PEDIATRICS ◽  
1969 ◽  
Vol 43 (2) ◽  
pp. 192-200
Author(s):  
Annette Silbert ◽  
Peter H. Wolff ◽  
Barbara Mayer ◽  
Amnon Rosenthal ◽  
Alexander S. Nadas
Keyword(s):  
Heart Disease ◽  
Congenital Heart ◽  
Motor Coordination ◽  
Fine Motor ◽  
General Intelligence ◽  
Cyanotic Heart Disease ◽  
Motor Tasks ◽  
The Third ◽  
Fine Motor Coordination ◽  
History Of

Forty-two children of normal intelligence with congenital heart disease between the ages of 4 and 8 years were tested for general intelligence, perceptual motor function, and gross and fine motor coordination. Three groups of children were tested: (1) those with cyanotic heart disease, (2) those with noncyanotic heart disease and a history of congestive heart failures, and (3) those with noncyanotic heart disease and a benign medical history. The first group had lower I.Q. scores, did less well in perceptual motor tasks, and had poorer gross motor coordination than children in the third group. Children of the second group occupied an intermediate position.

scholarly journals Gross Motor Development of Children with Congenital Heart Disease Receiving Early Systematic Surveillance and Individualized Intervention: Brief Report

2019 ◽  
Author(s):  
Solène Fourdain ◽  
Marie-Noëlle Simard ◽  
Lynn Dagenais ◽  
Manuela Materassi ◽  
Amélie Doussau ◽  
...  
Keyword(s):  
At Risk ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Physical Therapy ◽  
Motor Development ◽  
Congenital Heart ◽  
Gross Motor ◽  
Motor Abilities ◽  
Gross Motor Development ◽  
Risk Patients

Objective: In this pilot study, we described the gross motor development of infants aged 4 to 24 months with congenital heart disease (CHD) and assessed through a systematic develop&shy;mental screening programme, with individualised motor interventions. Methods: Thirty infants who had cardiac repair underwent gross motor evaluations using the AIMS at 4 months, and the Bayley-III at 12 and 24 months. Results: Based on AIMS, 80% of 4-month-old infants had a delay in gross motor development and required physical therapy. Gross motor abilities significantly improved by 24 months. Infants who benefited from regular physiotherapy tended to show better improvement in motor scores. Conclusion: Our study highlights the importance of early motor screening in infants with CHD and suggests a potential benefit of early physical therapy in those at-risk. Further research is needed to assess the effectiveness of systematic developmental screening and individualized inter&shy;vention programmes at identifying at risk patients, and their impact on developmental outcomes.

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