scholarly journals Efficacy of Tamsulosin in the Medical Management of Juxtavesical Ureteral Stones: A Randomized Control Trial

2017 ◽  
Vol 42 (2) ◽  
pp. 78-83 ◽  
Author(s):  
Abu Sayeed Md. Feroz Mustafa ◽  
Md. Saiful Islam ◽  
Abdullah Al Mamun ◽  
Muhammad Syeef Khalid

Urolithiasis is the third most common disease of the urinary tract. Among all urinary tract stones, majorities are ureteral stones located in the distal part of the ureters. At present, multimodalities of treatment are available to the urologists. The purpose of the present study was to observe the efficacy of Tamsulosin in conventional treatment of juxtavesical ureteric stone having size up to 8 mm. This was a single centered, parallel randomized control trial carried out in the outpatient department of Urology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from July 2007 to June 2008. The patients with unilateral, juxtavesical ureteral stone with normal functioning kidney and absence of clinical and laboratory signs of urinary tract infection and stone size up to 8 mm were included in the study. Patients were divided into two groups according to the computer generated simple random sampling. Patients of Group-A  were given conventional hydrotherapy treatment and patients of Group-B were given Tamsulosin 0.4mg/day along with the conventional hydrotherapy. Each patient was followed-up weekly until stone expulsion for 4 weeks. In Group-A and Group-B, the mean age with SD was 38.55±10.05 and 37.7±9.33 years. Expulsion occurred in 32 (53.33%) of 60 patients in Group-A and 51 (85%) of 60 patients in Group-B (p <0.05). The number of pain episodes in this study was statistically significantly lower in Group-B patients compared to Group-A (p <0.05). Urinary tract infection was encountered in 12 (20%) patients of Group-A and 2 (3.33%) patients of Group-B (p <0.05) during four weeks therapy which was treated by appropriate antibiotics. No side effects of Tamsulosin were encountered in any patients of Group-B which could require the cessation of the medication or might need for dose titration. Findings of the study revealed that the Tamsulosin supplemented conventional therapy is more effective than conventional hydrotherapy alone in management of juxtavesical ureteral stones.

2021 ◽  
pp. 1-2
Author(s):  
Shetti U. M. ◽  
Nandigoudar S.S. ◽  
Kalanghot P. S.

Urinary tract infections are the second most widespread infection and are elaborated in Ayurveda classical texts. The aim of the study is to compare the effect of the two well recognised and practised Ayurveda preparations in the treatment of urinary tract infection. 34 patients with proven UTI complaints in the age group of 20 to 60 years were randomly selected from out-patient and in-patient departments as per randomization chart and were divided into Group A and group B. Respectively in group A and group B, patients were advised 15 mL of Ardhabilwa kashaya and Brihatyadi kashaya before food thrice daily with equal quantity of water. After seven days follow up, assessment was done based on the clinical signs and symptoms. Urine examination at base th th line, 7 and at 15 day was performed.Study proved both drugs were clinically efcacious and statistically signicant in the management of urinary tract infection.


1989 ◽  
Vol 30 (4) ◽  
pp. 391-394
Author(s):  
L. Hannerz ◽  
I. Wikstad ◽  
G. Celsi ◽  
A. Aperia

The growth of the renal parenchyma was examined in children with duplicated outflow systems, vesicoureteral reflux (VUR), urinary tract infection (UTI) and no sign of obstruction. Ten patients with reflux occurring only in the caudal system (group A) and 4 patients with reflux both to the caudal and the apical system (group B) were studied shortly after their first UTI (study 1) and then 1.5 to 9 years later (study 2). The frequency of UTI was relatively high during the follow-up period. At urography, renal length and renal area were normal in group A in studies 1 and 2. Parenchymal thickness of the apical pole (APT/L) did not differ from normal values in any of the studies. Parenchymal thickness of the caudal pole (CPT/L) was significantly smaller than normal in both studies. There was also a significant decrease in CPT/L between study 1 and 2. UTI during the first year of life was associated with a greater reduction in CPT/L. The determination of renal length and renal area in children with a duplicated ureter, VUR and UTI, does not identify subjects at risk of developing renal growth retardation while serial determinations of parenchymal thickness appear to be an appropriate method.


2020 ◽  
Vol 22 (2) ◽  
pp. 110-117
Author(s):  
Md Mostafizur Rahman ◽  
Md Shafiqul Alam Chowdhury ◽  
Uttam Karmaker ◽  
Nazim Uddin Md Arif ◽  
Md Towhid Belal ◽  
...  

Objective: This study aims to evaluate the outcomes of PCNL without JJ ureteric stent in comparison to PCNL with JJ ureteric stent. Patients and Methods: This observational study intended to compare the outcome between PCNL without JJ stent and PCNL with JJ stent of 50 cases of renal stone disease according to the inclusion and exclusion criteria and randomly assigned to Group - A (PCNL without JJ stent) and Group - B (PCNL with JJ stent). This study was conducted in the department of urology, Dhaka Medical College Hospital from July 2014 to June 2016. During postoperative period, both groups were compared with respect to fever, loin pain, dysuria, frequency of micturation, duration of haematuria, continuation of urine leakage, hospital stay, urinoma and hematoma and urinary tract infection. Results: Among the 50 patients, the mean postoperative hospital stay was significantly longer in PCNL with JJ stent (4.48 ± 2.14 days) than that of PCNL without JJ stent (2.60 ± 0.50 days). The continuation of urine leakage at the site of percutaneous tract was also significantly longer in PCNL with JJ stent than in PCNL without JJ stent (10.8 ± 3.18 hours vs 14.14 ± 3.28 hours, P <0.001). Assessment of outcome during 3 weeks showed that out of 25 subjects in Group - B, 9 (36%) loin pain, 8 (32%) dysuria, 8 (32%) frequency of micturition, 4 (16%) haematuria and another 7 (28%) urinary tract infection. None of the subjects of Group - A reported same type of complications. Conclusions: Percutaneous Nephrolithotomy without JJ stent (stentless PCNL) is safe, effective and viable option in a selected group of patients – with stone size d”3 cm, normal preoperative renal function, single percutaneous puncture, minimum bleeding, no perforation of the collecting system, no obstruction and complete clearance of stones, JJ stent may not be required. Bangladesh Journal of Urology, Vol. 22, No. 2, July 2019 p.110-117


2020 ◽  
Vol 11 (1) ◽  
pp. 31-38
Author(s):  
Muhammed khalid ◽  
Muhammad Faizan ◽  
Muhammad Asif Gurmani ◽  
Amjad Ali Siddiqui ◽  
Qadeer Ahmed Choudhary ◽  
...  

ABSTRACT BACKGROUND & OBJECTIVE: To compare transurethral cystolithoclasty with ureteroscope over open vesicolithotomy in pediatric male patients. METHODOLOGY: Study comprises of hundred pediatric male patients, divided into two equal groups of 50 each, labeled as Group-A and Group-B. All the patients having stones less than 20mm size (average 14mm) were included. Group-A patients were treated with transurethral cystolithoclasty by using ureteroscope and pneumatic lithoclast assisted with the help of Dormia basket. Group-B patients were treated with open vesicolithotomy.RESULTS: All hundred male pediatric patients were between the ages of 1-15 years (mean age 8 years). Hospital stay was 2-3 days (average 2.5 days) in Group-A patients and 3-5 days (average 4 days) in Group-B patients. In Group-A3 (6%) patients had urinary tract infection, 1(2%) had urethral injury and 2(4%) had residual stone post-operatively. While Group-B4 (8%) suffered from urinary tract infection, 1(2%) had wound infection, 1(2%) had hematuria, and 2(4%) had fever. Retention of urine was 1(2%) in each Group. CONCLUSION: Transurethral cystolithoclasty is a much better way of treating vesical calculus in pediatric male patients because it is a procedure with short hospital stay, minimal invasion, no scar and less complication. KEYWORDS: Bladder Calculus, Comparison, Cystolithoclasty, Ureteroscope, Pneumatic Lithoclast, Dormia basket, Vesicolithotomy.


Author(s):  
Tanuka Barua ◽  
Razia Sultana ◽  
Pradip Kumar Datta ◽  
Jhulan Das Sharma ◽  
Md Rezaul Karim ◽  
...  

Context: UTI is one of the most common infection in nephrotic syndrome and may be a cause of delayed steroid response. Objective:To observe the impact of urinary tract infection on steroid response in idiopathic nephrotic syndrome children aged 2-6 years.Study design: Quasi experimental study Study period & place: Pediatric ward of Chittagong Medical College Hospital, Chittagong from 01.01.2009 to 31.12.2009. Participants: 52 Nephrotic syndrome children aged 2-6 years with typical clinical features Group A: Nephrotic syndrome with UTI, Group B: Nephrotic syndrome without UTI. Methods: Heat coagulation test, urine for R/M/E and C/S was done in every patient. Steroid was given according to standard regimen. Date of starting of steroid was recorded. Antibiotic was given in group A cases according to C/S report. Patients were followed for clinical and urinary remission. Group A and B were compared for remission time achieved by statistical method.Results: A male preponderance was noted about 57.7% against female about 42.3%. Generalized swelling of body & scanty micturation found in cent percent study group. Ascitis was found in 23.08%. Scrotal/labial swelling 7.69%.UTI developed in 30.8% of patients of NS. Male female ratio is 1:1. Infection delayed the remission of proteinuria. Mean remission time of NS without UTI patients was 7.39 days and with UTI patients was 9.31 days. In statistical analysis, mean remission time in group A =9.31+2.24 days(mean + SD), in group B=7.39+2.51 days(mean + SD), P value = <0.05, statistically significant.Conclusion: UTI in nephrotic syndrome causes delayed remission of proteinuria and may be asymptomatic.It should be screened in every nephrotic syndrome children routinely.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i2.21046


Author(s):  
Setareh Sagheb ◽  
Ziba Mosayebi ◽  
Zahra Nikseresht

Background: Determination of contributing factors for jaundice would result in better programming for prevention. This study was performed to determine the prevalence rate of Urinary Tract Infection (UTI) among neonates with jaundice admitted in Arash Hospital from October 2013 to October 2014. Methods: In this descriptive cross-sectional study, term neonates with non-hemolytic jaundice admitted in Arash Hospital from October 2013 to October 2014 were evaluated for UTI by urine culture and the data were recorded by checklist using medical documents. Results: A total of 436 term infants were enrolled in the study. Mean age at the time of admission was 6.03±3.355 days with age range of 3-18 days including 291(0.66%) males and 145(0.33%) females. Urine culture was positive in 32 neonates (7.3%).The most common germs were Klebsiella in 37.5%, Escherichia coli (E. coli) in 21.9%, Staphylococcus in 9.4%, Pseudomonas in 3.1%, Enterococcus in 15.6%, Enterobacter in 9.4%, and Group B Streptococcus (GBS) in 3.1%. Conclusion: Urine culture should be a part of routine clinical evaluation for all icteric neonates at the age of 5-6 days or more who have no risk factors to exclude the possibility of coincidental UTI.


2019 ◽  
Vol 5 (1) ◽  
pp. 64-68
Author(s):  
Ali Imam Ahsan ◽  
Nasimul Jamal ◽  
Ashfaq Ahmad ◽  
Syed Farhan Ali ◽  
Momenul Haque

Background: Treatment of granular myringitis (GM) is diverse with no definitive management. Objective: The aim of the present study was to see the effectiveness of different interventions for treating granular myringitis. Methodology: This was a single centred, parallel, randomized control trial. This study was done at the Specialized ENT Hospital of SAHIC, Dhaka from July 2010 to June 2012. Patients presenting with granular myringitis of 18 years of age or more with both sexes were included. All patients were divided into two groups by simple random sampling method of which patients of group A were treated by surgical treatment and that of group B were treated by medical treatment. Medical treatment was given in the form of topical ear drops and surgical treatment was performed by surgical debridement of granulation tissue followed by chemical cauterization. Repeated follow up was performed up to 6 months in both groups of treated patients. The primary outcome was the resolution of granulation tissue. During follow-up the secondary outcome variables were recurrence, perforation of the TM and any other complications or complain from the patients. Results: A total number of 60 patients were studied of which 30 patients were treated medically and 30 patients were treated surgically. The cure rate was higher in surgical treatment (80%) than conservative (16.7%) (p=0.011). The recurrence rate (17.24%) is also less in surgical group compared to medical treatment group (77.27%) (p=0.001). Conclusion: Surgical treatment is a more successful treatment modality for granular myringitis. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 64-68


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