scholarly journals Behavioral factors associated with the development of skin cancer in patients of arsenicosis

2018 ◽  
Vol 11 (2) ◽  
pp. 103
Author(s):  
Towhida Noor ◽  
Md. Shahidullah Sikder ◽  
Lubna Khondker ◽  
Mohammed Saiful Islam Bhuiyan ◽  
Tanvir Rahman
Keyword(s):  
Skin Cancer ◽  
Cell Carcinoma ◽  
Sun Exposure ◽  
The Body ◽  
Case Group ◽  
Skin Carcinoma ◽  
Bowen’S Disease ◽  
Behavioral Factors ◽  
Bowen's Disease ◽  
Factors Associated

<p>The study was conducted to evaluate the behavioral factors associated with the development of skin cancer in arsenicosis patients. Arsenicosis patients without skin cancer were taken as control. In the sun-exposed area of the body, 57.2% of skin carcinoma was Bowen’s disease. In the covered area of the body, 56.0% was Bowen’s disease, 36% was squamous cell carcinoma and 8% was basal cell carcinoma. Again, 53.1% of case and 59.4% of control never used fertilizer and pesticide. The majorities were non-smoker (case 53.1%, control 59.3%). Mean cumulative sun exposure was more in the case group (5853.9 ± 2219.7 hours) than in the control group (2219 ± 392.4 hours) and the rate of sun exposure was also higher in the case group. In conclusion, sun exposure was significantly higher in carcinoma patients and since most of the lesions were in the covered areas of the body, it can be said that these carcinomas were due to arsenicosis and not due to sun exposure and smoking status, use of fertilizer and pesticides were not associated with the development of skin carcinoma.</p>

scholarly journals Reflectance Confocal Microscopy of Pigmented Bowen’s Disease: A Case Series of Difficult to Diagnose Lesions

2020 ◽  
Vol 12 (2) ◽  
pp. 98-106
Author(s):  
Sara Mazzilli ◽  
Reyes Gamo-Villegas ◽  
Ana Pampin-Franco ◽  
Jose Luis Lopez Estebaran ◽  
Fernando Pinedo ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Histopathological Examination ◽  
Case Series ◽  
The Body ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Seborrheic Keratosis ◽  
Bowen's Disease ◽  
Precise Diagnosis

Pigmented Bowen’s disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. The best-characterized feature of the disease by histological examination is the presence of atypical keratinocytes, hyperpigmentation of the epidermis with trans-epidermal elimination of melanin and dermal melanophages. Precise diagnosis is often difficult, both clinically and dermoscopically, as Bowen’s disease is often mistaken with keratinocyte tumors such as solar lentigines, seborrheic keratosis, Bowenoid papulosis, pigmented basal cell carcinoma, pigmented actinic keratosis; or even melanocytic lesions such as melanocytic nevus, pigmented epithelioid melanocytoma, and melanoma. Precise diagnosis often requires biopsy and histopathological examination of the tissue. Reflectance confocal microscopy is a noninvasive technique to diagnose pigmented skin lesions. To date, not much data are available regarding its use in the diagnosis of pigmented Bowen’s disease. Herein, we report a well-represented case series of pigmented Bowen’s disease imaged using dermoscopy and reflectance confocal microscopy.

A Comprehensive Review on Nanotechnology-Based Innovations in Topical Drug Delivery for the Treatment of Skin Cancer

2020 ◽  
Vol 26 (44) ◽  
pp. 5720-5731 ◽  
Author(s):  
Arun Singh Lalotra ◽  
Vishesh Singh ◽  
Bharat Khurana ◽  
Shelly Agrawal ◽  
Shubham Shrestha ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Cell Carcinoma ◽  
Systemic Exposure ◽  
Chemotherapeutic Agents ◽  
The Body ◽  
Toxic Substances ◽  
Abnormal Growth ◽  
Dermal Layer ◽  
Therapeutic Benefits ◽  
Carrier Systems

Background: Skin is the largest organ of the body and helps to regulate several physiological functions. It acts as a barrier that protects the body against UV-radiation, toxic substances, infections, etc. The abnormal growth of the skin cells is called skin cancer. Different types of skin cancer can be classified as Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC); which mainly occur due to chronic exposure to UV- sunlight and pollution. Methods: The conventional topical treatments of skin cancer such as cream, gel, ointment, etc., are more occlusive and thus they do not penetrate deep into the skin (dermal layer) and remain at the upper part of the skin (epidermal layer). The stratum corneum acts as a physiological barrier for the drug-loaded in the conventional formulation. The novel carrier systems have the potential to facilitate the penetration of the drug deep into the skin (dermal layer) because these have less size and higher flexibility than conventional treatment. Conclusion: In the present review, we have discussed various novel carrier systems being investigated for the topical application of chemotherapeutic agents for efficient skin targeting and better dermatological as well as therapeutic benefits with minimal systemic exposure and toxicity.

Hugh Jackman vs. Skin Cancer Awareness Month: Promoting Public Interest in Basal Cell Carcinoma (Preprint)

2020 ◽  
Author(s):  
Trevor Torgerson ◽  
Jennifer Austin ◽  
Jam Khojasteh ◽  
Matt Vassar
Keyword(s):  
Social Media ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Moving Average ◽  
Public Awareness ◽  
Sun Exposure ◽  
Cancer Awareness ◽  
Autoregressive Integrated Moving Average

BACKGROUND Public awareness for BCC is particularly important, as its major risk factors — increased sun exposure and number of sunburns — are largely preventable. OBJECTIVE Determine whether social media posts from celebrities has an affect on public awareness of basal cell carcinoma. METHODS We used Google Trends to investigate whether public awareness for basal cell carcinoma (BCC) increased following social media posts from Hugh Jackman. To forecast the expected search interest for BCC, melanoma and sunscreen in the event that each celebrity had not posted on social media, we used the autoregressive integrated moving average (ARIMA) algorithm. RESULTS We found that social media posts from Hugh Jackman, a well-known actor, increased relative search interest above the expected search interest calculated using an ARIMA forecasting model. CONCLUSIONS Our results also suggest that increasing awareness by Skin Cancer Awareness Month may be less effective for BCC, but a celebrity spokesperson has the potential to increase awareness. BCC is largely preventable, so increasing awareness could lead to a decrease in incidence.

scholarly journals Testing Wearable UV Sensors to Improve Sun Protection in Young Adults at an Outdoor Festival: Field Study

10.2196/21243 ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. e21243
Author(s):  
Caitlin Horsham ◽  
Jodie Antrobus ◽  
Catherine M Olsen ◽  
Helen Ford ◽  
David Abernethy ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Field Study ◽  
Sun Exposure ◽  
Sun Protection ◽  
Incidence Rates ◽  
The Body ◽  
Childhood And Adolescence ◽  
Uv Sensor ◽  
Sunscreen Use ◽  
Uv Sensors

Background Australia and New Zealand have the highest skin cancer incidence rates worldwide, and sun exposure is the main risk factor for developing skin cancer. Sun exposure during childhood and adolescence is a critical factor in developing skin cancer later in life. Objective This study aims to test the effectiveness of wearable UV sensors to increase sun protection habits (SPH) and prevent sunburn in adolescents. Methods During the weeklong school leavers outdoor festival (November 2019) at the Gold Coast, Australia, registered attendees aged 15-19 years were recruited into the field study. Participants were provided with a wearable UV sensor and free sunscreen. The primary outcome was sun exposure practices using the SPH index. Secondary outcomes were self-reported sunburns, sunscreen use, and satisfaction with the wearable UV sensor. Results A total of 663 participants were enrolled in the study, and complete data were available for 188 participants (188/663, 28.4% response rate). Participants provided with a wearable UV sensor significantly improved their use of sunglasses (P=.004) and sunscreen use both on the face (P<.001) and on other parts of the body (P=.005). However, the use of long-sleeve shirts (P<.001) and the use of a hat (P<.001) decreased. During the study period, 31.4% (59/188) of the participants reported receiving one or more sunburns. Satisfaction with the wearable UV sensor was high, with 73.4% (138/188) of participants reporting the UV sensor was helpful to remind them to use sun protection. Conclusions Devices that target health behaviors when outdoors, such as wearable UV sensors, may improve use of sunscreen and sunglasses in adolescents.

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