scholarly journals Serum testosterone concentration in surgically castrated Black Bengal goats

2018 ◽  
Vol 33 (2) ◽  
pp. 71-77 ◽  
Author(s):  
M Hasan ◽  
MAH Miah ◽  
TA Rosy ◽  
PK Jha ◽  
NS Juyena

The experiment was carried out to detect the blood serum testosterone concentration after orchiectomy in Black Bengal bucks (Capra hircus). Twelve apparently healthy bucks of 8 - 10 months old were randomly divided into two groups. Group A were castrated surgically through open uncover method and group B remained intact. Local analgesia (2% lidocaine hydrochloride) @ 0.5 mL per spermatic cord and 0.5 mL at the tip of each scrotum were applied initially in all bucks. After aseptic preparation, incision was given at the tip of the scrotum and tunica vaginalis was incised to exteriorize the testis. Anchoring was done at the spermatic cord followed by orchiectomy. The scrotal raphe was incised to reach the other testis and the same procedure was followed. Blood samples were collected from jugular vein before orchiectomy and on day 30. In the castrated bucks, serum testosterone concentration was significantly (P<0.01) decreased from day 0 (6.1 ± 0.2 ng/mL) to day 30 (0.6 ± 0.0 ng/mL), which confirmed the efficacy of castration.Bangl. vet. 2016. Vol. 33, No. 2, 71-77

Author(s):  
Patil Aniket ◽  
Dindore Pallavi ◽  
Arbar Aziz ◽  
Kadam Avinash ◽  
Saroch Vikas

The quest for excellence in mental and physical health is not new. We find various references and formulations in Ayurvedic classics meant for promoting mental and physical health of a child. Suvarna Prashan is one of the formulations explained in age old Ayurvedic classic Kashyap Samhita. This formulation is very widely used now days as a memory and immune booster for children. But there is very little systematic documented study which can be used to evaluate the efficacy of the formulation. Suvarna Bhasma was prepared in Ayurved Rasayani Pharmacy, Pune. Madhu and Ghrita were collected from KLE Ayurveda Pharmacy, Belgaum. Suvarna Bindu Prashan was prepared in KLE Ayurved pharmacy, Belgaum. It contains Suvarna Bhasma, Ghrita and Madhu. Twenty apparently healthy male and female children with age group of three to four years were ready to sign inform consent form were selected into two groups each. Subjects in Group A received Suvarna Bindu Prashan where as Group B (Control group) did not receive any treatment. Both the groups were observed for six months. Children in Suvarna Bindu Prashan group showed significant reduction in the scores of eating habits, behavior, mood, temperament and scores of event of illness. However there was no significant difference in the score of sleeping habit. There was significant increase in IQ percentage.


2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110029
Author(s):  
Zhang Guo ◽  
Weiwei Wang ◽  
Dahua Xie ◽  
Ruisheng Lin

Objective To investigate the effect of supplemental dexmedetomidine in interventional embolism on cerebral oxygen metabolism in patients with intracranial aneurysms. Methods Ninety patients who underwent interventional embolism of intracranial aneurysms were equally divided into Group A and Group B. In Group A, dexmedetomidine was injected intravenously 10 minutes before inducing anesthesia, with a loading dose of 0.6 µg/kg followed by 0.4 µg/kg/hour. Group B received the same amount of normal saline by the same injection method. Heart rate (HR), mean arterial pressure (MAP), arterial–jugular venous oxygen difference [D(a-jv) (O2)], cerebral oxygen extraction [CE (O2)], and intraoperative propofol use were recorded before inducing anesthesia (T0) and at five time points thereafter. Results The amount of propofol in Group A was lower vs Group B. At all five time points after T0, HR, MAP, D(a-jv) (O2), and CE (O2) in Group A were significantly lower vs Group B, with significant differences for jugular venous oxygen saturation (SjvO2) and the oxygen content of the internal jugular vein (CjvO2) between the groups. Conclusion Dexmedetomidine resulted in less intraoperative propofol, lower D(a-jv) (O2) and CE (O2), and improved cerebral oxygen metabolism.


1934 ◽  
Vol 30 (11-12) ◽  
pp. 1206-1206
Author(s):  
Т. Charbet

Over the course of 11 years, 30,000 blood samples from inpatients were examined. The distribution by group gives the following result: Group 0-31.6%, Group A-42.2%, Group B- 14.7%, and Group AB-6.5%. There was no difference in the groups with regard to gender. For the indicated period of time the percentage, the ratio of groups did not change significantly.


2014 ◽  
Vol 5 (2) ◽  
pp. 95
Author(s):  
Ghulam Nabi ◽  
Muhammad Amin ◽  
Jeena Urooj ◽  
Muhammad Kamil ◽  
Ayaz Ali Khan

The objective of this study was to determine the effects of wood, cigarette and marijuana smoke on the reproductive health of tandoor occupants. A total of 100 male individuals were selected (50 control and 50 tandoor occupants). A standard questionnaire was designed regarding their age, economic status, marital status, fuel type, exposure time (per day), use of mask, addiction and reproductive health. Morning blood samples of 5 mL of the size were taken from all participants. Serums were obtained and analyzed for total serum testosterone concentration. Bio-check (USA) kit was used according to the manufacturer protocol and procedures for testosterone analysis. In control group the mean ± SEM of total serum testosterone was 671.9 ± 20.02 ng/dl where as in tandoor occupants it was 542.7 ± 16.40 ng/dl. There was a significant reduction (P**** < 0.0001) in total serum testosterone concentration in tandoor occupants as compared to control group. Reproductive health problems like, low libido, erection problems, infertility, decreased frequency for shaving and absent morning and nocturnal erection were common in tandoor occupants as compared to control group. Wood, cigarette and marijuana smoke negatively affects testosterone concentration and lowers it significantly. This reduced testosterone concentration then produces ill effects like low libido, erection problems, infertility and absent morning and nocturnal erection. 


Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 5292-5292
Author(s):  
Qian Jiang ◽  
Xiao Jun Huang ◽  
Kaiyan Liu ◽  
Huan Chen ◽  
Yuhong Chen ◽  
...  

Abstract Objective To evaluate the alterations in coagulation in patients during modified busulfan plus cyclophosphamide (BUCY) ± antithymocyte globulin (ATG) before allogeneic hematopoietic stem cell transplantation (allo-HSCT), and to assess the effect of ATG on coagulation system as part of conditioning regimen. Methods Thirty-five patients with various hematological malignancies undergoing allo-HSCT were assessed. Nineteen patients from HLA-identical siblings (group A) were conditioned with modified BUCY regimen, included cytarabine (2g/m2 i.v., day -9), busulfan (4mg/kg p.o. in divided doses daily, day -8 to day -6), cyclophosphamide (1.8g/m2 i.v., day -5 and day -4) and Me-CCNU (250mg/ m2 p.o., day -3). Sixteen patients from HLA-mismatched family members or HLA-matched unreleated donors (group B) were conditioned with modified BUCY + ATG regimen, added cytarabine (4g/m2 i.v., day -10 and -9) and rabbit ATG (2.5mg/kg i.v., day -5 to day -2, SangStat S.A.S., France). Blood samples were obtained before the start of regimen until day +1 after allo-HSCT. The following laboratory parameters were measured: prothrombin time (PT), active partial thromboplastin time (APTT), Fgrinogen (Fg), antithrombin (AT), D-Dimer, Fgrin degradation product (FDP), platelet (PLT), liver enzymes and bilirubin. VIII:C, IX:C, XI:C and XII:C in some blood samples with prolonged APTT were determined. Clinical hemorrhagic symptoms were monitored. Results From day -5 of conditioning regimens, temporary lengthening of APTT, which peaked on day -3, occurred in 16/19 (84.2%) patients in group A and 19/19 (100%) patients in group B, continued rise in Fg occurred in 17/19 (89.5%) patients in group A and 19/19 (100%) patients in group B, a progressive decrease of PLT was observed in all patients of two groups. Alterations of Fg and PLT were more significant in group B compared to those in group A. Transient D-Dimer increase was detected only in group B on day -3. Among intrinsic pathway coagulation factors, XII:C and XI:C were decreased commonly and significantly when APTT was prolonged. No difference between the two groups could be found with regard to PT, FDP, AT and liver parameters which remained nearly in normal ranges. Most of patients in two groups did not have overt bleeding manifestations. Conclusions Modified BUCY ± ATG conditioning regimen can induce subclinical alterations in coagulation. The regimen contained ATG has more significant effect on coagulation parameters.


1992 ◽  
Vol 126 (5) ◽  
pp. 404-409 ◽  
Author(s):  
CG Semple ◽  
R Mitchell ◽  
S Hollis ◽  
WR Robertson

LH pulsatility studies were performed in six burned patients by removing blood samples at 10 min intervals over a 6 h period. All samples were assayed for LH by bioassay (B-LH), LH by radioimmunoassay (I-LH) and testosterone. Mean serum testosterone concentrations of the burned patients were low (6.7±1.6 nmol/l). I-LH levels were lower than B-LH in all samples. Frequency of bioactive or immunoreactive pulses as well as mean B-LH and I-LH concentrations were similar to previously published data from normal men examined in the same laboratory. The mean biological activity of LH (expressed as the ratio of B-LH to I-LH, the B:I ratio) was lower in burned subjects (1.9±0.1) than previously reported in normal men. The B:I ratios of burned men were lower (p <0.01) at pulse peaks than at nadirs (1.8±0.1 vs 2.0±0.1) and an increase in serum testosterone concentration did not follow an LH peak. Serum testosterone concentrations did not cross-correlate with B-LH or I-LH. This contrasts with the findings in normal subjects where the B:I ratios have been found to be higher at pulse peaks than at nadirs and an increase in serum testosterone concentration follows a pulse peak and serum testosterone cross-correlates with B-LH and I-LH. LH secreted in a pulse peak in normal men may contain a particularly biologically potent form of the molecule but this may not be the case in burned men.


2020 ◽  
Vol 10 (03) ◽  
pp. 421-425
Author(s):  
Suad Azeez Hassan ◽  
Suhair Hassan Alkutbi ◽  
Eman S. Nassir ◽  
Haider Hassan Lilo

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are counted as a public health issue worldwide. The virus is transmitted to infect others through blood and blood products. Appointed blood groups and Rh-positive are more prone to the transmission of the infection by blood transfusion. The aim of this study is to find out the frequency of hepatitis B and C in apparently healthy blood donors and whether there is an association between ABO and Rh blood groups. ABO blood groups and their relationship with HBV and HCV infections were studied in 87,124 blood donors of both genders. Out of these donors, 353 individuals were found to be infected with HBV and HCV with a ratio of 1:250. The study was conducted between January to June 2018, which was presented to the Central Blood Bank in Baghdad and Al-Razi Medical Centre. It found that most hepatitis B and C blood donors were blood group O with a prevalence of 33.7 and 45.5%, respectively, while the results for those with blood group A showed 28.5 and 22.7% HBV and HCV infections, respectively. On the other hand, the incidence of HBV in individuals with blood group B was 29.8%, and HCV was 23.8%. AB blood group donors demonstrated the least incidence at 7.9% for both HBV and HCV. In conclusion, it has been found that there is a significant association between blood groups and Rh factor with hepatitis B and C infections.


2021 ◽  
Vol 44 (1) ◽  
pp. 55-62
Author(s):  
Adewale Ayodeji Adeyeye ◽  
Yusha'u Usman Abubakar ◽  
Olufisayo Oluwadamilare Leigh ◽  
Iyorhembe Utim Ate ◽  
Jashilagari Stephen ◽  
...  

Abstract Pregnancy-specific protein B (PSPB) is produced by mono and binucleate trophoblast cells in the placenta of ruminants during pregnancy. This study was designed to determine the pattern of serum PSPB in Yankasa ewes during pregnancy and postpartum periods. Mature cycling Yankasa ewes were synchronized and divided into two groups A (n=11) and B (n=13). Group A was bred, while group B was unbred. Blood samples for PSPB assessment were collected from the ewes starting from the day of breeding until 4 weeks post-lambing. All pregnant Yankasa ewes lambed with singleton lambs after an average of 151.18 days. There was a significant (p<0.05) increase in PSPB in pregnant compared with the non-pregnant ewes in the period between 3 weeks post-breeding and 3 weeks post-lambing. Peaks were detected in the first (100.60 ng/ml), second (133.90 ng/ml), and third (114.82 ng/ml) trimesters at 5, 10 and 21 weeks of gestation, respectively, but steadily decreased within 4 weeks (2.38 ng/ml) postpartum. In conclusion, PSPB detected pregnancy in Yankasa ewes from 3 weeks post-breeding with peak levels at 5, 10 and 21 weeks post-breeding in the first, second, and third trimesters, respectively. PSPB decreased gradually after lambing until 4 weeks postpartum.


2021 ◽  
Vol 6 (3) ◽  
pp. 201-203
Author(s):  
Shallu Chaudhary ◽  
Ravikant Dogra ◽  
Ramesh Kumar

The study was carried out in 80 patients admitted in ICU and OT at IGMC Shimla. Patients were divided into 2 groups:- group A (short axis) and group B(long axis) of 40 patients each. Internal jugular vein cannulation was done under USG guidance using the two techniques. We were successfully able to cannulate all the patients. We obtained vascular access with higher first pass success and less number of needle passes using short axis approach compared to long axis. Keywords: internal jugular vein cannulation, USG guided approach, short axis versus long axis technique, Central vein catheterization


2014 ◽  
Vol 21 (01) ◽  
pp. 111-115
Author(s):  
Zahidullah Khan ◽  
Inamullah Khan ◽  
Fazle Subhan

Objective: To compare the efficacy of Simvastatin with Atorvastatin in loweringLow Density Lipoprotein Cholesterol (LDL-C) in patients with Hypercholesterolemia in a tertiarycare hospital. Design: Prospective, observational, single center study. Setting: Department ofMedicine, Khyber Teaching Hospital, Peshawar. Period: December 2011 to December 2012.Subjects and Methods: A total of 200 cases having base line fasting LDL-C level of ≥ 130 mg/dland meeting the inclusion criteria were included in the study through both outpatient department(OPD) and admitted patient. After detailed history and clinical examination, all patients weredivided randomly into two groups, A and B. Patients in Group A were given Simvastatin20mg/day and Group B received Atorvastatin 20mg/day. Fasting blood samples were taken fromthe selected patients in the start of study and after 12 weeks. Results: A total of 200 subjects witha serum LDL-C level ≥ 130 mg/dL were included in the study. They were divided into 2 groupsrandomly, 100 in each group. Each group comprised of 75 male and 25 female. The mean age ingroup A was 52 years and in group B it was 54 years. The age ranges between 40 years and 73years. Mean base LDL-C level was 165 mg/dl in group A and 170mg/dl in group B. Simvastatin 20mg/dl reduced LDL-C level by 26% and Atorvastatin 20mg/dl reduced LDL-C level by 33% after 12weeks of treatment. Conclusions: Atorvastatin is a more effective drug to reduce serum LDLcholesterolthan Simvastatin in the same doses.


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