scholarly journals Vitamin A Concentration in Cord and Maternal Serum and its Relation to Birth Weight

1970 ◽  
Vol 3 (1) ◽  
pp. 9-12
Author(s):  
Dipi Barua ◽  
TA Chowdhury ◽  
Ashim Ranjan Barua
Keyword(s):  
Birth Weight ◽  
Child Health ◽  
Vitamin A ◽  
Growth And Development ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Maternal Serum ◽  
Poor Survival ◽  
And Child Health ◽  
Training Institute

Low birth weight (LBW) is a common problem in Bangladesh associated with poor survival, growth and development. Among many factors, Vitamin A deficiency is thought to be associated with LBW. To investigate this relation a study was conducted at Maternity and Child Health Training Institute at Azimpur, Dhaka during January 2000 - July 2002. One hundred pregnant women (38-40 wks of gestation) with their newborns were included. Weights of the newborns were recorded within 20 - 30 minutes of delivery. Vitamin A level was estimated in maternal and cord serum. The newborns having weight <2500gm showed Vitamin A level of 49.40 ± 3.04μg/dl in their maternal serum while those weighing ≥2500gm had a Vitamin A level of 60.18 ± 2.03μg/dl in their maternal serum. A trend of increased maternal serum Vitamin A level was observed with increasing birth weight. Thus neonates with higher birth weights were found to be associated with higher values of maternal serum Vitamin A, though not being statistically significant. Ibrahim Med. Coll. J. 2009; 3(1): 9-12 Key words: LBW, Vitamin A, cord blood, neonates     doi: 10.3329/imcj.v3i1.2911

scholarly journals Maternal vitamin A status in intrauterine growth retarded babies

2017 ◽  
Vol 8 (3) ◽  
pp. 30-34 ◽  
Author(s):  
Alakh Ram Verma ◽  
Prafulla Kumar Khodiar ◽  
Debapriya Rath ◽  
Seema Dhurandhar ◽  
Pradeep Kumar Patra
Keyword(s):  
Birth Weight ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Maternal Serum ◽  
Control Group ◽  
Study Group ◽  
Intrauterine Growth ◽  
Vitamin A Status ◽  
Low Serum

Background: Beside calorie and protein consumption micronutrients like folic acid, vitamin D and vitamin A have been postulated to play major role in intrauterine growth of neonates. Vitamin A compounds are critical for vision, reproduction, embryonic development, immune function and regulation of cell proliferation and differentiation.Aims and Objectives: To determine the relationship of maternal serum vitamin A levels with birth weight of babies.Material and Methods: Study group consisted of 58 randomly selected mothers who delivered at term small for gestational age babies (birth weight less than 2.5kg.). The control group comprises of 52 matched mothers, who delivered normal babies. Biochemical estimation of serum vitamin A was done by HPLC method using sigma reagent of all subjects.Results: Significantly high (p<0.05) number of mothers in study group had low serum vitamin A level compared to mothers in control group. There was a linear relationship between vitamin A status and mean birth weight of the babies.Conclusion: Although the low serum vitamin A level of mothers was significantly associated with intrauterine growth retardation, the exact effect of a vitamin A deficiency on the birth weight of babies remain unclear, but the finding suggests the importance of adequate vitamin A supplementation to pregnant mothers in India.Asian Journal of Medical Sciences Vol.8(3) 2017 30-34

scholarly journals Vitamin A Concentration in Cord and Maternal Serum and its Effects on Birth Weight

1970 ◽  
Vol 33 (2) ◽  
pp. 46-49 ◽  
Author(s):  
Dipi Barua ◽  
Begum Nasrin ◽  
KN Nahar ◽  
Shayela Shamim ◽  
Ashim Ranjan Barua ◽  
...  
Keyword(s):  
Birth Weight ◽  
Child Health ◽  
Vitamin A ◽  
Randomized Study ◽  
Child Survival ◽  
Serum Vitamin ◽  
Maternal Serum ◽  
Physical Growth ◽  
Cord Serum ◽  
The Difference

Introduction: Birth weight is a reliable index of intra-uterine growth and a major factordetermining child survival, future physical growth and mental development.Objectives: The present study was designed to explore the association of maternalserum as well as cord serum vitamin A level with birth weight.Materials and Methods: This prospective randomized study was carried out in Maternityand Child Health Training Institute (MCHTI), Azimpur, Dhaka during the period fromJanuary to July, 2002 on 100 healthy pregnant mothers of 38-40 weeks of gestationand on 100 new born babies born to these mothers.Results: Mean birth weight was 2804 gm (±43.1) with a range of 1600-3900 gm. Cordserum vitamin A level was 583 (±1.73) μg/dl with a range of 4.9-102.04 μg/dl, whilematernal serum vitamin A level was 53.5μg/dl (±1.5) with a range of 17.2-89.2 μg/dl.Newborn having birth weight ≥ 2500gm was found to have higher level of maternalserum vitamin A than the newborn having weight <2500gm, (54.5±1.6 μg/dl vs 49.4±3.04μg/dl, p=.06) but the difference was not statistically significant. There was no significantdifference in cord serum vitamin A level between two groups of newborn (57.8±2.06μg/dl vs. 60.2±2.03 μg/dl, p=.2).Key words: Vitamin A concentration; birth weight.DOI: 10.3329/bjch.v33i2.5676Bangladesh Journal of Child Health 2009; Vol.33(2): 46-49

Effects of vitamin A deficiency during pregnancy on maternal and child health

2002 ◽  
Vol 109 (6) ◽  
pp. 689-693 ◽  
Author(s):  
M.S. Radhika ◽  
P. Bhaskaram ◽  
N. Balakrishna ◽  
B.A. Ramalakshmi ◽  
Savitha Devi ◽  
...  
Keyword(s):  
Child Health ◽  
Vitamin A ◽  
Maternal And Child Health ◽  
Vitamin A Deficiency ◽  
And Child Health

The association between maternal fat-soluble vitamin concentrations during pregnancy and infant birth weight in China

2020 ◽  
pp. 1-9
Author(s):  
Wangxing Yang ◽  
Mingyuan Jiao ◽  
Lei Xi ◽  
Na Han ◽  
Shusheng Luo ◽  
...  
Keyword(s):  
Birth Weight ◽  
Vitamin E ◽  
Vitamin A ◽  
Serum Vitamin ◽  
Positive Association ◽  
Maternal Serum ◽  
Vitamin Status ◽  
High Concentrations ◽  
Fat Soluble Vitamins ◽  
Infant Birth

Abstract Fat-soluble vitamins during pregnancy are important for fetal growth and development. The present study aimed at exploring the association between vitamin A, E and D status during pregnancy and birth weight. A total of 19 640 women with singleton deliveries from a retrospective study were included. Data were collected by the hospital electronic information system. Maternal serum vitamin A, E and D concentrations were measured during pregnancy. Logistic regression was performed to estimate the association between the vitamin status and low birth weight (LBW) or macrosomia. Women with excessive vitamin E were more likely to have macrosomia (OR 1·30, 95 % CI 1·07, 1·59) compared with adequate concentration. When focusing on Z scores, there was a positive association between vitamin E and macrosomia in the first (OR 1·07, 95 % CI 1·00, 1·14), second (OR 1·27, 95 % CI 1·11, 1·46) and third (OR 1·28, 95 % CI 1·06, 1·54) trimesters; vitamin A was positively associated with LBW in the first (OR 1·14, 95 % CI 1·01, 1·29), second (OR 1·31, 95 % CI 1·05, 1·63) and third (OR 2·00, 95 % CI 1·45, 2·74) trimesters and negatively associated with macrosomia in the second (OR 0·79, 95 % CI 0·70, 0·89) and third (OR 0·77, 95 % CI 0·62, 0·95) trimesters. The study identified that high concentrations of vitamin E are associated with macrosomia. Maintaining a moderate concentration of vitamin A during pregnancy might be beneficial to achieve optimal birth weight. Further studies to explore the mechanism of above associations are warranted.

scholarly journals Association between Total and Individual PCB Congener Levels in Maternal Serum and Birth Weight of Newborns: Results from the Chiba Study of Mother and Child Health Using Weighted Quantile Sum Regression

2022 ◽  
Vol 19 (2) ◽  
pp. 694
Author(s):  
Akifumi Eguchi ◽  
Kenichi Sakurai ◽  
Midori Yamamoto ◽  
Masahiro Watanabe ◽  
Aya Hisada ◽  
...  
Keyword(s):  
Birth Weight ◽  
Child Health ◽  
Regression Model ◽  
Maternal Serum ◽  
Maternal Exposure ◽  
Serum Samples ◽  
Pcb Congeners ◽  
Mother And Child Health ◽  
Mother And Child ◽  
And Child Health

Maternal exposure to polychlorinated biphenyls (PCBs) during pregnancy is associated with a low birth weight; however, the congener-specific effects of PCB congeners are not well defined. In this study, we used maternal serum samples from the Chiba Study of Mother and Child Health (C-MACH) cohort, collected at 32 weeks of gestational age, to analyze the effects of PCB congener exposure on birth weight by examining the relationship between newborn birth weight and individual PCB congener levels in maternal serum (n = 291). The median total PCB level in the serum of mothers of male and female newborns at approximately 32 weeks of gestation was 39 and 37 ng g−1 lipid wt, respectively. The effect of the total PCB levels and the effects of PCB congener mixtures were analyzed using a linear regression model and a generalized weighted quantile sum regression model (gWQS). The birth weight of newborns was significantly associated with maternal exposure to PCB mixtures in the gWQS model. The results suggest that exposure to PCB mixtures results in low newborn birth weight. However, specific impacts of individual PCB congeners could not be related to newborn birth weight.

scholarly journals Night Blindness and Vitamin A Deficiency following Jejunoilieal Bypass Surgery

1989 ◽  
Vol 3 (4) ◽  
pp. 138-140
Author(s):  
Paul C. Adams ◽  
Christopher L. Canny
Keyword(s):  
Vitamin A ◽  
Night Blindness ◽  
Bypass Surgery ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Jejunoileal Bypass ◽  
Intestinal Bypass ◽  
Oral Vitamin ◽  
Visual Deficits ◽  
Nutritional Vitamin

A 42-year-old man who developed severe night blindness 15 years following jejunoileal bypass surgery for morbid obesity is described. Ophthamological testing, including dark adaptation, electroretinography and serum vitamin A levels, confirmed a diagnosis of vitamin A deficiency. Oral vitamin A 25,000 iu/day for two months resulted in a full recovery of visual deficits. Nutritional vitamin A deficiency is discussed in the context of intestinal bypass surgery.

High coverage of vitamin A supplementation and measles vaccination during an integrated Maternal and Child Health Week in Sierra Leone

2014 ◽  
Vol 7 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Fatmata F. Sesay ◽  
Mary H. Hodges ◽  
Habib I. Kamara ◽  
Mohamed Turay ◽  
Adam Wolfe ◽  
...  
Keyword(s):  
Child Health ◽  
Vitamin A ◽  
Sierra Leone ◽  
Maternal And Child Health ◽  
High Coverage ◽  
Vitamin A Supplementation ◽  
Measles Vaccination ◽  
And Child Health

scholarly journals Use of biomarkers of sub-clinical infection, nutrition and neonatal maturity to interpret plasma retinol in Nigerian neonates

2003 ◽  
Vol 90 (2) ◽  
pp. 353-361 ◽  
Author(s):  
Delana A. Adelekan ◽  
Christine A. Northrop-Clewes ◽  
Joshua A. Owa ◽  
Adesola O. Oyedeji ◽  
Adedayo A. Owoeye ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Geometric Mean ◽  
Plasma Concentrations ◽  
Surrogate Marker ◽  
Public Health Problem ◽  
World Health ◽  
Plasma Retinol

Using the World Health Organization criterion, the prevalence of sub-clinical vitamin A deficiency can be assessed using plasma retinol concentrations <0·7 μmol/l. However, plasma retinol can be depressed by infection; thus, the use of this criterion alone may overestimate deficiency. In the present study, we investigated the usefulness of the acute-phase proteins (APP) α1-antichymotrypsin (ACT) and α1-acid glycoprotein (AGP), plasma carotenoids and anthropometric and gestational indices to interpret plasma retinol in the blood of 192 apparently healthy Nigerian neonates collected randomly during days 1–20 postpartum. The mean weight (2·64 kg) and length (0·458 m) of the neonates and plasma concentrations (geometric mean, μmol/l) of retinol (0·54), α-carotene (0·072), ß-carotene (0·076) and lutein (0·080) were low. The prevalence of vitamin A deficiency was 72 %, indicating a severe public health problem. Babies who were of low birth weight (P<0·003) or premature and low birth weight (P<0·023) had significantly lower retinol concentrations than full-term normal weight babies. Thirty-two neonates had abnormal ACT and forty-four abnormal AGP concentrations. Positive correlations between retinol and ACT (r0·186,P=0·05) and AGP (r0·31,P=0·0001) during days 1–5 may be due to the increasing plasma retinol from maternal milk and a coincidental increasing capacity to synthesise APP. Subsequently, negative correlations between retinol and ACT (r−0·28,P=0·02) and AGP (r−0·29,P=0·018) from day 6 onwards reflected the continuing increase in plasma retinol, but no further increase in the APP. Overall, weight, ACT, lutein and age explained 30 % of the variance in retinol, but lutein was the most significant (r20·18,P<0·0001). Hence, the distribution of plasma retinol concentrations in this group of neonates was more strongly linked with nutrition (via the surrogate marker lutein) than infection.

Vitamin a Deficiency and Severe Bronchopulmonary Dysplasia in Very Low Birth Weight Infants

1996 ◽  
Vol 13 (07) ◽  
pp. 389-393 ◽  
Author(s):  
Rita Verma ◽  
Kristine McCulloch ◽  
Leslie Worrell ◽  
Dharmapuri Vidyasagar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Vitamin A ◽  
Bronchopulmonary Dysplasia ◽  
Very Low Birth Weight ◽  
Vitamin A Deficiency ◽  
Low Birth Weight Infants
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