scholarly journals Diabetic Cardiac Autonomic Dysfunction and Its Relationship with Duration of Diabetes

2016 ◽  
Vol 11 (1) ◽  
pp. 1-5
Author(s):  
Phurpa ◽  
Sultana Ferdousi
Keyword(s):  
Type 2 Diabetes ◽  
Autonomic Dysfunction ◽  
Negative Relationship ◽  
Duration Of Diabetes ◽  
Cardiac Autonomic Dysfunction ◽  
Male Patients ◽  
Relationship Of ◽  
The Relationship

Background: Duration of diabetes may have an important influence on cardiac autonomic dysfunction in type 2 diabetes mellitus.Objective: To assess the relationship of cardiac autonomic dysfunction in type 2 diabetes mellitus(T2DM) with the duration of diabetes.Methods: This crosssectional study was carried out from January to December 2015 on 54 long-term T2DM male patients aged 45 to 55 years, selected from the Endocrinology OPD of BSMMU, Dhaka. Thirty age matched recently diagnosed male T2DM patients(RT2DM) were control. Cardiac autonomic function was assessed by Heart Rate Variability(HRV). HRV measures were obtained by RMS multi channel polyrite-D. For statistical analysis, unpaired t-test and Pearson’s correlation coefficient test were used.Results: Mean RR, SDNN, and HF nu were significantly lower (p < 0.001) whereas, mean HR, LF nu and LF/HF were significantly (p < 0.001) higher in LT2DM than those of RT2DM. SDNN, RMSSD and variance showed significant (p < 0.001) negative correlation with the duration of diabetes.Conclusions: Duration of diabetes had strong negative relationship with the diabetic cardiac autonomic dysfunction.Bangladesh Soc Physiol. 2016, June; 11(1): 1-5

scholarly journals A study of cardiological autonomic neuropathy in Type 2 Diabetes Mellitus with reference to QT interval for its diagnosis

2019 ◽  
Vol 7 (7) ◽  
pp. 2574
Author(s):  
Lakshmi Priya Inapakolla ◽  
Ramgopal Teja Kotla
Keyword(s):  
Type 2 Diabetes ◽  
Autonomic Neuropathy ◽  
Autonomic Dysfunction ◽  
Cardiovascular Autonomic Neuropathy ◽  
Cardiac Autonomic Neuropathy ◽  
P Value ◽  
Qtc Interval ◽  
Duration Of Diabetes ◽  
Cardiac Autonomic Dysfunction

Background: Presence of cardiac autonomic neuropathy (CAN) is responsible for silent myocardial infarction and sudden death in diabetics. Hence recognizing cardiac dysautonomia early, which is asymptomatic will help to delay or arrest its progression.Methods: A cross-sectional study to evaluate the Prevalence of Cardiovascular Autonomic Neuropathy in Type 2 diabetes and correlate it with duration of Diabetes and to investigate the relationship between cardiac autonomic dysfunction and corrected QT interval.Results: In the study population, the prevalence of definite CAN was 8%, 24% and 58% in group A, B and C respectively. The prevalence of definite CAN increases with increase in duration of diabetes. P value <0.001 significant.Conclusions: A significant correlation is present between Cardiovascular autonomic dysfunction and QTc prolongation. QTc interval in the ECG can be used to diagnose Cardiovascular autonomic neuropathy with a reasonable sensitivity and specificity.

scholarly journals The ApoE4 genotype modifies the relationship of long-term glycemic control with cognitive functioning in elderly with type 2 diabetes

2014 ◽  
Vol 24 (8) ◽  
pp. 1303-1308 ◽  
Author(s):  
Ramit Ravona-Springer ◽  
Anthony Heymann ◽  
James Schmeidler ◽  
Mary Sano ◽  
Rachel Preiss ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Cognitive Functioning ◽  
Relationship Of ◽  
The Relationship

The Relationship of Depression, Anxiety and Disability with HbA1c and the Duration of Diabetes in Patients with Type 2 Diabetes Mellitus

2012 ◽  
Vol 13 (3) ◽  
pp. 115-119 ◽  
Author(s):  
Esma Guldal Altunoglu ◽  
Zeynep Sari ◽  
Fusun Erdenen ◽  
Cuneyt Muderrisoglu ◽  
Ender Ulgen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Duration Of Diabetes ◽  
Relationship Of ◽  
The Relationship

542-P: Association of Cardiac Autonomic Dysfunction with Plasma Lipid Metabolites in Recent-Onset Type 2 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 542-P
Author(s):  
GIDON J. BÖNHOF ◽  
ALEXANDER STROM ◽  
KLAUS STRASSBURGER ◽  
BIRGIT KNEBEL ◽  
JORG KOTZKA ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Autonomic Dysfunction ◽  
Plasma Lipid ◽  
Recent Onset ◽  
Onset Type ◽  
Cardiac Autonomic Dysfunction ◽  
Lipid Metabolites

scholarly journals Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes

2018 ◽  
Vol 132 (23) ◽  
pp. 2509-2518 ◽  
Author(s):  
Gargi Mahapatra ◽  
S. Carrie Smith ◽  
Timothy M. Hughes ◽  
Benjamin Wagner ◽  
Joseph A. Maldjian ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
White Matter ◽  
African Americans ◽  
Mitochondrial Function ◽  
Brain Morphology ◽  
Intracranial Volume ◽  
Peripheral Blood Mononuclear ◽  
Relationship Of ◽  
The Relationship

Blood-based bioenergetic profiling has promising applications as a minimally invasive biomarker of systemic bioenergetic capacity. In the present study, we examined peripheral blood mononuclear cell (PBMC) mitochondrial function and brain morphology in a cohort of African Americans with long-standing Type 2 diabetes. Key parameters of PBMC respiration were correlated with white matter, gray matter, and total intracranial volumes. Our analyses indicate that these relationships are primarily driven by the relationship of systemic bioenergetic capacity with total intracranial volume, suggesting that systemic differences in mitochondrial function may play a role in overall brain morphology.

scholarly journals Relationship of Type 2 Diabetes Mellitus Duration with The Occurrence of Erectile Dysfunction at Puskesmas Denpasar Barat I

2021 ◽  
Vol 2 (1) ◽  
pp. 23-28
Author(s):  
Alexander Petra Sihite ◽  
I Gusti Ngurah Pramesemara ◽  
I Wayan Surudarma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Erectile Dysfunction ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Number Of Patients ◽  
Relationship Of ◽  
The Relationship

Background: Type 2 diabetes mellitus is a metabolic disease that characterized by high blood sugar levels. This condition is often not noticed immediately and usually patient starting to realize it when complications have been occurred. A long-term complication of type 2 DM that occurred in men is erectile dysfunction (ED). ED is a condition when a person is unable to achieve or maintain an erection for sexual intercourse. One factor that influence the occurrence of ED and its severity in type 2 DM patients is the duration of the disease. Objective: The aim of this study was to determine the relationship of type 2 DM duration and the occurrence of ED. Methods: This study is an observational analytic cross-sectional study conducted at the Puskesmas (Public Health Center) Denpasar Barat I. The research data was obtained through medical record data and fill the International Index of Erectile Function (IIEF-5) questionnaire on 36 type 2 DM patients aged around 40-60 years. The statistical analysis used was Fisher's exact test. Results: The results showed that of the 36 samples, 19 (52.8%) samples had type 2 DM <24 months and 17 (47.2%) samples had type 2 DM >24 months. It was found that 5 (13.9%) samples did not experience ED while the rest experienced ED with different severity. There was a significant relationship between the type 2 DM duration and the occurrence of erectile dysfunction at Puskesmas Denpasar Barat I (p = 0.022). Conclusion: Study has found that type 2 DM patients with the longer duration (>24 months)  have a higher occurrence of ED and tended to be more severe compared to those with shorter duration (<24 months). Further studies should be performed with higher number of patients and more controlled risk factor so it will be more accurate in determining the relationship between the duration of type 2 DM and ED.

scholarly journals Postprandial Blood Pressure Decrease in Patients with Type 2 Diabetes and Mild or Severe Cardiac Autonomic Dysfunction

2019 ◽  
Vol 16 (5) ◽  
pp. 812
Author(s):  
Masahiko Hashizume ◽  
Saori Kinami ◽  
Keiichi Sakurai ◽  
Kazuhiro Izawa ◽  
Hideyuki Shiotani
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Systolic Blood Pressure ◽  
Autonomic Dysfunction ◽  
Control Group ◽  
Cardiac Autonomic Dysfunction ◽  
Patients With Diabetes ◽  
Severe Group ◽  
Meal Ingestion

Background Few reports have evaluated the relationship between changes in postprandial blood pressure and the severity of autonomic dysfunction in patients with type 2 diabetes. This was a cross-sectional study designed to investigate postprandial blood pressure changes in individuals without type 2 diabetes and patients with type 2 diabetes and mild or severe cardiac autonomic dysfunction. Methods Forty patients with type 2 diabetes mellitus and 20 individuals without type 2 diabetes participated in this study. Fifty-two participants underwent a meal tolerance test. Blood pressure (brachial systolic blood pressure (bSBP) and central systolic blood pressure (cSBP)), electrocardiogram recordings, and blood samples were assessed before and after meal ingestion. Patients with diabetes were divided into two groups based on their coefficient of variation of R–R intervals (CVRR): a normal or mildly dysfunctional group (mild group, CVRR ≥ 2%; n = 20) and a severely dysfunctional group (severe group, CVRR < 2%; n = 15). Results In the control group, bSBP and cSBP did not significantly change after meal ingestion, whereas both decreased significantly at 60 min after meal ingestion in the mild and severe groups. While blood pressure recovered at 120 min after meal ingestion in the mild group, a significant decrease in blood pressure persisted at 120 min after meal ingestion in the severe group. Conclusions Based on these results, adequate clinical attention should be paid to the risk of serious events related to postprandial decreases in blood pressure, particularly in patients with diabetes and severe cardiac autonomic dysfunction.

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