scholarly journals Relationship of Blood Groups (ABO & Rhesus) and Breast Cancer in Bangladesh

2014 ◽  
Vol 4 (2) ◽  
pp. 106-109
Author(s):  
Ghulam Mostafa Khan ◽  
Md Rahmatullah ◽  
Ishita Mostafa
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Distant Metastasis ◽  
Large Scale ◽  
Positive Family History ◽  
Blood Groups ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Female Patients ◽  
Relationship Of

Correction: On the website, on 16/08/2014, the first author was changed from Chulam Mostafa Khan TO Ghulam Mostafa Khan. The PDF was correct.Background: The association of blood groups with breast cancer in our country is not fully established elaborately and large scale studies have not been carried out till now. Therefore this study was designed to find out the possible relationship of different blood groups with breast cancer. Objective: To determine the relationship of various types of breast cancer with ABO and Rh blood groups among the female patients of our people.Materials and Methods: This cross sectional study was conducted in the cancer unit of Delta Medical College and Hospital, Dhaka from January 2011 to February 2013. After proper and ethical consideration total 112 female patients with breast cancer were included in this study. Various factors like age, family history, metastasis, type of cancer were considered in this study. The blood groups of the patients were done by standard ABO and Rh typing methods (Forward & Reverse grouping by test tube method).Results: Among 112 breast cancer patients of our country, ductal breast cancer was found in 108 (96.42%) subjects, distant metastasis was found in 93 (86.9%) cases and positive family history in 70 (62.50%) subjects.Conclusion: Ductal type of breast cancer with positive family history and distant metastasis is common in different blood groups in our country.DOI: http://dx.doi.org/10.3329/jemc.v4i2.19679J Enam Med Col 2014; 4(2): 106-109

The relationship of self-acceptance with decision making duration in cancer patient to perform mastectomy

2021 ◽  
pp. 1-5
Author(s):  
Ayu Ratuati Setiawan ◽  
Feny Tunjungsari ◽  
Mochamad Aleq Sander
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Abnormal Growth ◽  
Self Acceptance ◽  
Observation Method ◽  
Relationship Of ◽  
The Relationship

BACKGROUND: Cancer is a disease caused by abnormal growth of body cells that turn malignant and continue to grow uncontrollably. One of the treatments for breast cancer is mastectomy. The quickness of decision-making determines the survival rate of prognosis patients. OBJECTIVE: This study aimed to determine the relationship of self-acceptance with decision-making duration in cancer patients to perform a mastectomy. METHODS: An analytic observation method with cross-sectional design. The samples were taken by purposive sampling method with 50 samples of breast cancer patients. Data collected include age, last level of education, marital status, profession, stage of cancer during mastectomy, self-acceptance score, and decision-making duration to perform a mastectomy. RESULTS: The data analyzed with the Kruskal–Wallis test. The test showed the relationship of self-acceptance (p = 0.027) with decision-making duration in breast cancer patients to perform a mastectomy. CONCLUSION: In Conclusion, there is a relationship of self-acceptance with decision-making duration in breast cancer patients to perform a mastectomy.

Breast-conservation therapy in early-stage breast cancer patients with a positive family history

2002 ◽  
Vol 9 (9) ◽  
pp. 912-919 ◽  
Author(s):  
Georges Vlastos ◽  
Nadeem Q. Mirza ◽  
Funda Meric ◽  
Kelly K. Hunt ◽  
Attiqa N. Mirza ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Early Stage ◽  
Positive Family History ◽  
Breast Conservation ◽  
Breast Conservation Therapy ◽  
Early Stage Breast Cancer ◽  
Breast Cancer Patients

The Importance of Family History in Breast Cancer Patients in Primary Care Setting: a Cross-sectional Study

2017 ◽  
Vol 33 (3) ◽  
pp. 602-609
Author(s):  
Mehtap Kartal ◽  
Nilgun Ozcakar ◽  
Sehnaz Hatipoglu ◽  
Makbule Neslisah Tan ◽  
Azize Dilek Guldal
Keyword(s):  
Breast Cancer ◽  
Primary Care ◽  
Family History ◽  
Cancer Patients ◽  
Care Setting ◽  
Primary Care Setting ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals BREAST CANCER;

2014 ◽  
Vol 21 (06) ◽  
pp. 1128-1132
Author(s):  
Abeer Nisar ◽  
M Naim Siddiqi ◽  
Naveed ur Rehman ◽  
Raza ur Rahman
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Family History ◽  
Menopausal Status ◽  
Positive Family History ◽  
American Woman ◽  
Breast Cancer Patients ◽  
Civil Hospital ◽  
Early Menarche ◽  
History Of

Objective: To assess the risk factors for breast cancer in patients attending oncology OPD of civil hospital Karachi, Pakistan. Introduction: Breast cancer is the single largest cause of death among women1,2. The probability of American woman developing breast cancer in their life is 7 in 11. Studies from subcontinent show that the incidence of breast cancer is increasing, with an estimated 80,000 new cases diagnosed annually. Breast cancer is the second most common type of cancer after lung cancer in Pakistan and ranked first in women. Only 10% women are diagnosed, out of them, 75% women do not get treatment and die within 5 years6. Data from Pakistan about the risk factors or association is not only scanty but also does not comment on the use of fatty diet in breast cancer patients. Method: A cross-sectional descriptive study conducted at Oncology OPD of civil hospital Karachi (CHK) from October 2009 -April 2011. One Hundred and Fifty consecutive patients having histopathalogical diagnosis of breast cancer were assessed for different risk factors that included marital status, parity, age, menopausal status, family history of breast cancer, prolong use of oral contraceptives, breast feeding, , early menarche, trauma to the breast and fatty diet. Result: Mean age of patients was 48 years. Three fourth (73%) of these female were above the age of 40 years. Consumption of fatty diet was found in 62.67% while positive family history of breast cancer was present in 34% of the cases. Early menarche and being nulliparous were not as strong risk factors as in previous studies. Conclusions: Our study has highlighted the need of further exploration in this area that would not only help this population but also enhance our understanding of different risk factors. This will have important implications for the overall management of breast cancer.

scholarly journals Prevalence and Spectrum of Breast Cancer Inherited Mutations in Uganda and Cameroon Women

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 43s-43s
Author(s):  
B. Adedokun ◽  
Y. Zheng ◽  
P. Ndom ◽  
A. Gakwaya ◽  
T. Makumbi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Positive Family History ◽  
Pathogenic Mutation ◽  
Germline Mutations ◽  
Sub Saharan Africa ◽  
Age At Diagnosis ◽  
Breast Cancer Patients ◽  
Brca1 And Brca2 ◽  
Sub Saharan

Background: Breast cancer among indigenous Africans is characterized by higher prevalence of triple-negative disease and poor prognosis. A previous study in Nigeria reported a strikingly high prevalence of deleterious germline mutations in BRCA1 and BRCA2 among Nigerian women with breast cancer. It is unknown if this is true in other sub-Saharan African countries. Aim: The objective of this study is to determine the frequency of germline mutations among an unselected sample of women in Africa. Methods: We conducted a case-control study of breast cancer in Uganda and Cameroon to investigate genetic and nongenetic risk factors for breast cancer. Breast cancer cases were enrolled in two tertiary hospitals in the two countries, unselected for age at diagnosis and family history. Controls who were free of breast cancer were enrolled in the same hospitals and matched to cases on age. A 24-gene sequencing panel was used to test germline mutations in cases and controls. Results: There were 176 cases and 177 controls with a mean age at diagnosis of 46.2 years for cases and mean age at interview of 46.7 years for controls. Among cases, 18.2% carried a pathogenic mutation in a breast cancer gene: 6.3% in BRCA1, 6.3% in BRCA2, 1.7% in ATM, 1.1% in PALB2, 0.6% in BARD1, 0.6% in CDH1, 0.6% in TP53, and 1.2% in any of 17 other genes. Among controls, 2.3% carried a pathogenic mutation in one of the 24 susceptibility genes. Cases were 9.6-fold more likely to carry a mutation compared with controls (odds ratio=9.61, 95% confidence interval: 3.28-38.1; P < 0.001). The mean age of breast cancer cases with pathogenic BRCA1 mutations was 38.3 years compared with 46.7 years among other cases without such mutations ( P = 0.03). There was a trend that cases with a positive family history had higher chance of carrying a mutation (33.3%) than cases without (17.1%), but few cases reported a positive family history. Conclusion: Our findings confirm the earlier report of a high proportion of deleterious mutations in BRCA1 and BRCA2 among breast cancer patients in sub-Saharan Africa. As most of these women present with advanced breast cancer, there is an urgent need to improve access to genomic testing and life saving cancer medicines including chemotherapy and clinical trials of novel agents like PARP inhibitors. Given the high burden of inherited breast cancer, genetic risk assessment should be integrated into cancer control plans in sub-Saharan Africa.

scholarly journals Breast Cancer Knowledge and Screening Behaviour among Women with a Positive Family History: A Cross Sectional Study

2013 ◽  
Vol 14 (11) ◽  
pp. 6783-6790 ◽  
Author(s):  
Pathmawathi Subramanian ◽  
Nelson Ositadimma Oranye ◽  
Azimah Mohd Masri ◽  
Nur Aishah Taib ◽  
Nora Ahmad
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Cancer Knowledge ◽  
Sectional Study ◽  
Cross Sectional ◽  
Breast Cancer Knowledge

scholarly journals Social, Demographical, and Clinical Correlates of Stigma in Iranian Breast Cancer Women

2021 ◽  
Author(s):  
Hadi Zamanian ◽  
Mohammadali Amini-Tehrani ◽  
Mona Daryaafzoon ◽  
Zahra Jalali ◽  
Fatemeh Sabeghi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Chronic Diseases ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Background Data ◽  
Related Stigma ◽  
History Of

Abstract Background: This study aimed to assess the severity of disease-related stigma felt by Iranian women with breast cancer as well as to determine the contextual correlates of stigmatization.Methods: This cross-sectional study included 223 breast cancer patients between October-2014 and May-2015, in Tehran, Iran. Eligible patients were asked to provide background data and to complete Stigma Scale for Chronic Illness 8-item (SSCI-8) questionnaire. Binomial logistic regression analysis was employed to identify stigmatized (SSCI-8 > 8) and heavily stigmatized (SSCI-8 >10) groups.Results: A total of 58.3% (n=130) stated that they were stigmatized at least “rarely.” In the multi-variable models in the total sample, living with spouse, Turkic ethnicity, family history of chronic diseases were the significant associations of stigmatization, while no variable was found to be associated with heavily stigmatization. In the sub-sample having the data of spouse’s education (n=185), living with spouse, lower spouse’s education, and family history of chronic diseases were the significant correlates of stigmatization; while, in terms of heavily stigmatization, only the lower spouse’s education was the significant indicator.Conclusions: Stigmatization tails women with breast cancer especially those living with their poorly educated husbands which call for dyadic interventions.

scholarly journals Analysis of BRCA1 and BRCA2 mutations in Brazilian breast cancer patients with positive family history

2005 ◽  
Vol 123 (4) ◽  
pp. 192-197 ◽  
Author(s):  
Rozany Mucha Dufloth ◽  
Sílvia Carvalho ◽  
Juliana Karina Heinrich ◽  
Júlia Yoriko Shinzato ◽  
César Cabello dos Santos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Positive Family History ◽  
Breast Cancer Patients ◽  
Brca1 And Brca2 ◽  
Cancer Susceptibility Genes ◽  
Brca2 Mutations ◽  
Exon 11 ◽  
Brca1 And Brca2 Mutations

CONTEXT AND OBJECTIVE: BRCA1 and BRCA2 are the two principal hereditary breast cancer susceptibility genes, and the prevalence of their mutations among Brazilian women is unknown. The objective was to detect BRCA1 and BRCA2 mutations in Brazilian patients with breast cancer, so as to establish genetic profiles. DESIGN AND SETTING: Cross-sectional study, in Centro de Atenção Integral à Saúde da Mulher, Universidade Estadual de Campinas, Brazil, and Institute of Pathology and Molecular Immunology, University of Porto, Portugal. METHODS: Thirty-one breast cancer patients with positive family history (criteria from the Breast Cancer Linkage Consortium) were studied, and genomic DNA was extracted from peripheral blood. Single-strand conformation polymorphism was used for the analysis of exons 2, 3, 5, and 20 of BRCA1. Cases showing PCR products with abnormal bands were sequenced. Exon 11 of BRCA1 and exons 10 and 11 of BRCA2 were directly sequenced in both directions. RESULTS: Four mutations were detected: one in BRCA1 and three in BRCA2. The BRCA1 mutation is a frameshift located at codon 1756 of exon 20: 5382 ins C. Two BRCA2 mutations were nonsense mutations located at exon 11: S2219X and the other was an unclassified variant located at exon 11: C1290Y. CONCLUSION: The BRCA1 or BRCA2 mutation prevalence found among women with breast cancer and such family history was 13% (4/31). Larger studies are needed to establish the significance of BRCA mutations among Brazilian women and the prevalence of specific mutations.

scholarly journals Fatalism in breast cancer and performing mammography on women with or without a family history of breast cancer

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Maryam Molaei-Zardanjani ◽  
Mitra Savabi-Esfahani ◽  
Fariba Taleghani
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Positive Family History ◽  
Screening Method ◽  
Cross Sectional Study ◽  
Data Collection Tool ◽  
Cross Sectional ◽  
History Of ◽  
The Mean ◽  
Spss Software

Abstract Background Breast cancer is the most prevalent cancer in women, and in those with a positive family history, it is important to perform mammography. One of the probable barriers in doing mammography is fatalism. Methods This is a descriptive/cross-sectional study conducted on 400 women residing in Isfahan, Iran, randomly selected in 2017. Sampling was done randomly among the enrolled women in Health Integrity System. The data collection tool was a questionnaire regarding the demographic-fertility information and fatalism. The data analysis was done by SPSS software. A P-value < 0.05 was considered statistically significant. Results The results showed that the mean rate of fatalism was 59.5 ± 23.2 in women with the experience of mammography, and 65.9±18.7 in women without the experience. Moreover, the mean rate of fatalism was 73.1±15.2 in subjects with a family history of breast cancer, and 59.3 ± 22.5 in those no family history related to this condition. Accordingly, fatalism was statistically significant associated (P < 0.001) with a family history of breast cancer and experience of mammography. There was no significant relationship between demographic information and fatalism (P > 0.05). Conclusion The results indicated that fatalism in women with no experience of mammography was higher than in those with a positive history. Regarding the necessity of mammography in women with a family history of breast cancer, the required interventions seem to be essential to changing the viewpoints of women regarding the importance and effect of mammography as a screening method for breast cancer.

The relationship of family support with decision-making duration in cancer patient to perform a mastectomy

2021 ◽  
pp. 1-5
Author(s):  
Feny Tunjungsari ◽  
Ayu Ratuati Setiawan ◽  
Mochamad Aleq Sander
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Family Support ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Abnormal Growth ◽  
Relationship Of ◽  
The Relationship ◽  
Bivariate Test

BACKGROUND: Cancer is a disease caused by abnormal growth of body cells that turn malignant and continue to grow uncontrollably. One of the treatments for breast cancer is mastectomy. The quickness of decision-making determines the survival rate of prognosis patients. OBJECTIVE: This study aimed to determine the relationship of family support with decision-making duration in cancer patients to perform a mastectomy. METHODS: An analytic observation method with cross-sectional design. The samples were taken by purposive sampling method with 50 samples of breast cancer patients. Data collected include age, last level of education, marital status, profession, stage of cancer during mastectomy, family support score, and decision-making duration to perform a mastectomy. The data analyzed with the Kruskal-Wallis bivariate test. RESULTS: The bivariate test showed the relationship of family support (p = 0.002) with decision-making duration in breast cancer patients to perform a mastectomy. CONCLUSION: There is a relationship between family support with decision-making duration in breast cancer patients to perform a mastectomy.

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