scholarly journals CYTOCHROME P-­450 AND VKORC1 GENETIC POLYMORPHISMS IN NENETS ­ - AN INDIGENOUS ETHNIC GROUP IN THE ARCTIC

Human Ecology ◽  
2020 ◽  
pp. 11-17
Author(s):  
N. A. Vorobyeva ◽  
A. I. Vorobyeva
Keyword(s):  
Ethnic Group ◽  
Genetic Polymorphisms ◽  
The Arctic ◽  
Indigenous Ethnic Group ◽  
Cytochrome P 450

scholarly journals Features of the phenotypic and genotypic lipid status of the indigenous ethnic group of the Arctic in the conditions of island living

2020 ◽  
pp. 44-55
Author(s):  
N. A. Vorobyeva ◽  
N. I. Belova ◽  
A. I. Vorobyeva
Keyword(s):  
Ethnic Group ◽  
Metabolic Diseases ◽  
Arctic Region ◽  
The Arctic ◽  
Genetic Profile ◽  
Cross Sectional ◽  
Genetic Characteristics ◽  
Lipid Status ◽  
Indigenous Ethnic Group ◽  
Reported Study

Introduction. Dyslipidemia and obesity are interdisciplinary and “multi-metabolic” diseases, pathogenetically associated with the development of atherothrombosis, which creates practical health problems. The development of both dyslipidemia and obesity is influenced by socio-demographic, environmental, genetic and many physiological and behavioral factors, while the contribution of genetic factors is 40-70%. The goal is to identify the genetic characteristics oflipid status and fat metabolism in the indigenous ethnic group of the Arctic region of the Russian Federation under conditions of permanent islandliving.Methods. A cross-sectional population study of an indigenous ethnic group (n = 44) living on Vaygach Island (70 ° 01 ' Nlat 59 ° 33 ' E). The reported study was funded by RFBR according to the research project №18-00-00814-(18-00-00478). Serum cholesterol and triglycerides were determined as markers oflipid metabolism in blood serum. To analyze the genetic profile, the polymorphism of the FTO A23525T gene and the LPL Ser447Ter gene was determined by polymerase chain reaction.Results. In the sample of the indigenous ethnic group, BMI was 26.0 [21.5; 29.75] kg/m2. BMI for men is 23.0 [18.0; 28.0] kg/m2, for women - 25.0 [18.0; 29.25] kg / m2. Carriers of the unfavorable allele A had a higher BMI than carriers of the T allele. Analysis of the effect of rs9939609 genetic polymorphism on thelevel of total cholesterol did not show statistically significant differences between the FTO gene genotypes. A minimal triglyceride concentration was observed in carriers of the protective genotype Ter/Ter.Conclusion. Understanding the similarities and differences in genetic susceptibility among different ethnic groups can ultimately contribute to a more focused primary prevention and patient-oriented approach of cardiovascular pathology. 

scholarly journals Genetic polymorphisms analysis of pharmacogenomic VIP variants in Bai ethnic group from China

2019 ◽  
Vol 7 (9) ◽  
Author(s):  
Wanlu Chen ◽  
Heng Ding ◽  
Yujing Cheng ◽  
Qi Li ◽  
Run Dai ◽  
...  
Keyword(s):  
Ethnic Group ◽  
Genetic Polymorphisms

Sport Psychology Consulting With Indigenous Athletes: The Case of New Zealand Māori

2011 ◽  
Vol 5 (4) ◽  
pp. 350-360 ◽  
Author(s):  
Ken Hodge ◽  
Lee-Ann Sharp ◽  
Justin Ihirangi Heke
Keyword(s):  
New Zealand ◽  
Ethnic Group ◽  
Sport Psychology ◽  
Cultural Practices ◽  
Psychological Intervention ◽  
Final Analysis ◽  
Skills Training ◽  
Research And Practice ◽  
Indigenous Ethnic Group ◽  
Kaupapa Māori

Sport psychology consulting with athletes who are from an indigenous ethnic group presents some challenges and opportunities that do not typically need to be considered when consulting with nonindigenous athletes. Māori1 are the indigenous ethnic group of New Zealand. To work as a sport psychology consultant with Māori athletes and indeed any indigenous athletes (e.g., Tahitian, First Nation Canadian Indian) it is important for the sport psychologist to have an understanding of Te Ao o Nga Tāngata Whenua (indigenous worldview) and tīkanga Tāngata Whenua (indigenous cultural practices; Hanrahan, 2004; Schinke & Hanrahan, 2009; Tuhiwai-Smith, 1999). Both research and practice in the social sciences regarding Māori people seek to use a Kaupapa Māori (Māori research and practice platform) approach. Kaupapa Māori attempts to ensure that cultural sensitivity is infused from the conceptualization of an intervention (e.g., psychological skills training, psychological intervention) through to the design, delivery, evaluation, final analysis, and presentation of the intervention or research project. A Kaupapa Māori approach to sport psychology consulting attempts to ensure that key Māori aspirations are honored and celebrated, as many Māori do not wish to follow a non-Māori ideology that depersonalizes the whānau (family) perspective and seeks individuality in its place (Durie, 1998a; Mead, 2003). Therefore, an effective sport psychology consulting program for an athlete who lives her or his life from a Te Ao Māori (Māori worldview) and tīkanga Māori (Māori cultural practices) perspective needs to be constructed as a Māori-for-Māori intervention based within a Kaupapa Māori framework.

A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma

2004 ◽  
Vol 2 (8) ◽  
pp. 704-712 ◽  
Author(s):  
Andrew T. Chan ◽  
Gregory J. Tranah ◽  
Edward L. Giovannucci ◽  
David J. Hunter ◽  
Charles S. Fuchs
Keyword(s):  
Prospective Study ◽  
Genetic Polymorphisms ◽  
Colorectal Adenoma ◽  
A Prospective Study ◽  
Cytochrome P 450

Role of cytochrome P-450 genetic polymorphisms in oral carcinogenesis

2011 ◽  
Vol 41 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Miriam Hernando-Rodriguez ◽  
Natalia Rey-Barja ◽  
Xabier Marichalar-Mendia ◽  
Maria J. Rodriguez-Tojo ◽  
Amelia Acha-Sagredo ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Oral Carcinogenesis ◽  
Cytochrome P 450

scholarly journals The Melanau Fisherman

2018 ◽  
Vol 17 (2) ◽  
Author(s):  
Christina Amanda Yin
Keyword(s):  
Ethnic Group ◽  
Short Story ◽  
Coastal Wetlands ◽  
Small Town ◽  
Extended Family ◽  
Group Living ◽  
Family Culture ◽  
Indigenous Ethnic Group ◽  
Malaysian Borneo

The Melanau people are an indigenous ethnic group living in the coastal wetlands in the southwestern region of Sarawak, Malaysian Borneo. Mukah, famed as the Melanau heartland, is a small town known for its fishing and sago industries. Set in Mukah, this short story tells the tale of two Melanau sisters faced with an unexpected change in their family circumstances leading to a clash of gender, extended family, culture and occupation.

scholarly journals Clinical and genetic factors determining target lesions of patients with arterial hypertension among Mountain Shoria population

2017 ◽  
Vol 14 (3) ◽  
pp. 42-50
Author(s):  
T A Mulerova
Keyword(s):  
Arterial Hypertension ◽  
Protective Effect ◽  
Ethnic Group ◽  
Russian Federation ◽  
Mthfr Gene ◽  
Ace Gene ◽  
Indigenous Ethnic Group ◽  
The Russian Federation ◽  
High Level ◽  
Agt Gene

Objective. To establish associations between clinical and genetic risk factors and target lesions (heart, blood vessels, kidneys) of patients with arterial hypertension (AH) among the population of Mountain Shoria, depending on ethnicity. Matherials and methods. A clinical and epidemiological study of compactly living population in the remote areas of the Mountain Shoria was carried out. This middle altitude region is located in the south of Western Siberia. 1409 people were examined (901 representatives of the indigenous ethnic group - the Shors, 508 representatives of the non-indigenous ethnic group - 90% of them being Caucasian). The diagnosis of AH was set in accordance with the recommendations of the Society of Cardiology of the Russian Federation / Medical Society of the Russian Federation on the Problem of Arterial Hypertension, 2010. Assessment of the structural and functional state of the cardiac muscle and duplex scanning of brachiocephalic arteries among the patients with AH was made by echocardiography. A photometric method was used to examine the urinary albumin concentration level. The polymorphisms of the genes ACE (I/D, rs4340), АGT (c.803T>C, rs699), AGTR1 (А1166С, rs5186), ADRB1 (с.145A>G, Ser49Gly, rs1801252), ADRA2B (I/D, rs28365031), MTHFR (c.677С>Т, Ala222Val, rs1801133) and NOS3 (VNTR, 4b/4a) were tested by the PCR method. Results. Among the members of the indigenous ethnic group left ventricle hypertrophy (LVH) correlated with the AG progression features (extent and duration), smoking, genotypes I/D of the ACE gene among men and T/T and C/T of the MTHFR gene; increased intima-media complex thickness (IMT) correlated with the AG progression features (duration), male sex, age, genotypes T/C of the AGT gene and C/T of the MTHFR gene; high level of albuminuria (AU) correlated with the AG progression features (extent and duration), lipid disorders (hypoalphacholesterolemia, hypertriglyceridemia, hyperbetacholesterolemia), genotypes D/D and I/D of the ACE gene, D/D of the ADRA2B gene and the C/T of the MTHFR gene among 18-64-year-olds. Genotype T/C of the AGT gene had a protective effect on LVH, genotypes G/G and A/G of the ADRB1 gene had protective effects on IMT and AU levels. In the nonindigenous ethnic group LVH correlated with the AG progression features (duration), hypertriglyceridemia, abdominal obesity, genotypes D/D of the ACE gene, 4b/4a and 4a/4a of the NOS3 gene; increased IMT correlated with the AG progression features (duration), age and genotypes T/C and C/C of the AGT gene; AU high level correlated with the AG progression features (extent and duration), obesity, abdominal including, genotypes C/C of the AGTR1 gene, D/D of the ADRA2B gene and T/T of the MTHFR gene. Genotype I/D of the ADRA2B gene had protective effect on IMT. Conclusion. The study demonstrated the importance of the ethnogenetic mechanisms in the multifactorial pathology development. The problem requires further research, also identification of people with AH and target lesions is needed for monitoring during the prophylactic medical examination of the population.

scholarly journals Meretas Jalan Damai di Perbatasan Panti Rao Pasaman Sumatera Barat

2019 ◽  
Vol 3 ◽  
Author(s):  
Januar
Keyword(s):  
Ethnic Group ◽  
Ethnic Groups ◽  
Religious Identity ◽  
Ethnic Diversity ◽  
Social Institutions ◽  
Religious Communities ◽  
Community Based ◽  
Indigenous Ethnic Group ◽  
Religious Dialogue ◽  
Protestant Christianity

The Pao Rao Pasaman area is a multi-ethnic area that is not only inhabited by Minangkabau ethnic as an indigenous ethnic group, but some ethnic migrants such as Mandailing, Malay and Toba Batak. In addition to ethnic diversity, in Rao there is also a diversity of religious beliefs embraced by ethnic groups that inhabit this border area. Islam is a religious identity for Minangkabau and Mandailing in Rao. While the Toba and Javanese Batak ethnic groups adhered to Catholicism and Protestant Christianity. The problem that arises in this Panti is that understanding understanding diversity still contains sentiments and considers them the most correct, cultural and religious dialogue spaces between plural community communities are still lacking and have not yet formed a peaceful community in the Panti community based on places of worship and social institutions. The results of the empowerment of the multicultural and religious communities showed that there was an understanding of the workshop participants living harmoniously between religious communities and not the community did not consider it the most correct, and the formation of inter-community cultural and religious dialogue at the Pasaman Home.  Keywords: hacking, peaceful way, border   Daerah Panti Rao Pasaman merupakan daerah multi etnik yang tidak hanya dihuni oleh etnik Minangkabau sebagai etnik asli, tetapi beberapa etnik pendatang seperti Mandailing, Melayu dan Batak Toba. Di samping keragaman etnik, di Rao juga terdapat keragaman keyakinan agama yang dianut oleh etnik-etnik yang mendiami daerah perbatasan ini. Islam merupakan identitas keagamaan bagi etnik Minangkabau dan Mandailing di Rao. Sedangkan kelompok etnik Batak Toba dan Jawa menganut agama Katolik dan Kristen Protestan. Permasalahan yang muncul di Panti ini adalah pemahaman keagaman masih mengandung sentimen dan menganggap mereka paling benar, ruang dialog budaya dan agama antar Komunitas masyarakat plural  masih Minim dan belum terbentuk komunitas damai  dalam  masyarakat Panti  yang berbasis rumah ibadah dan lembaga social. Hasil pemberdayaan komunitas multicultural dan agama menunjukan bahwa adanya pemahaman peserta workshop hidup rukun antar umat beragama dan tidak komunitas tidak menganggap paling benar, dan terbentuknya ruang dialog budaya serta agama antar Komunitas di Panti Pasaman. Kata Kunci: Meretas, Jalan damai, Perbatasan

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