scholarly journals FACTORS ASSOCIATED WITH HEPATITIS B AND C CO-INFECTION AMONG PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS IN VIETNAM

2019 ◽  
Vol 5 (4) ◽  
pp. 147-154
Author(s):  
Le Hieu Thuy Anh ◽  
Suchada Thaweesit

Background: Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are the leading causes of death from infectious diseases. Because of sharing same transmission routes, the co-infection of HIV with HBV or HCV is common. And the co-infections make HIV infected persons have higher morbidity and mortality than those who infected only with HIV. This study aims to investigate factors that may have influence on the co-infections of HBV or HCV among HIV positive individuals.Objective: The goals of this study were to identify factors associated with the co-infection of HBV or HCV among people living with HIV. Methods: Quantitative research method was applied in this study to examine factors associated with HBV or HCV co-infection among HIV infected people. A total of 250 HIV infected individuals in Khanh Hoa province, Vietnam were the sample of this study. It employed the Social Ecological Model (SEM) as a theoretical perspective that focused on multiple levels of factors. Descriptive statistic was used to describe the general characteristics of the respondents. And Binary logistic regression was carried out to measure the influence of factors on the co-infection. Results: The multivariate analysis of this study showed that HIV-HBV co-infection was associated significantly with residents of Nha Trang (OR= 7.179). Regarding HIV-HCV co-infection, being men (OR= 7.617), unemployed (OR= 4.013), a resident of Nha Trang (OR=10.894) and an injecting drug user (OR= 16.688) were risk factors of the co-infection.Conclusions: This study recommended that intervention strategies to prevent HIV-positive individuals from co-infection with either HBV or HCV should focuses on altering individuals’ risk behaviors and their socio-economic environments. Also, specific preventing programs should be implemented and focus on unemployed populations, injecting drug users, men in general, as well as people living in particular areas, especially cities having a large number of people living with HIV.

2018 ◽  
Vol 1 (1) ◽  
pp. 9-20
Author(s):  
Marie Lauren Michelle Hortillas ◽  
Lisa Anna Gayoles

The present study aimed to investigate the lived experiences of beingHIV positive; to describe common themes of experiences of being HIVpositive; and to analyze the meaning of experiences of being HIV positive.The participants of this study were five HIV-positive men under the careof the Department of Health (DOH) Region VI in Iloilo City. Specifically,they belonged to the United Western Visayas Incorporated (UWVI), acommunity-based group of people living with HIV (PLHIV) based in Iloiloand operating in Panay and Guimaras areas. Narrative writing encouragedthe participants to rummage through emotions tied to being HIV positive.This gave them the chance to revisit strong feelings without divulging theiridentities, thus protecting their anonymity. Eight main textural themesemerged from the lived experiences of these men, namely: disclosureof HIV-positive status; stigma and discrimination attached to HIV; socialsupport from family, friends, and others; depression accompanying thediagnosis; the physical symptoms experienced during seroconversion;antiretroviral therapy after the diagnosis; and HIV advocacy with UWVI.These HIV positive men have metamorphosed, from the acceptanceof their HIV positive status to reinventing their new reality and findingpurpose through their HIV advocacy. The findings suggest implications forsupportive counseling to provide empathy, support and encouragement,and developing specific coping strategies with PLHIV.


2019 ◽  
Author(s):  
Agnes Bwanika Naggirinya

BACKGROUND : Adherence to treatment is critical to obtain successful treatment outcomes. While factors influencing antiretroviral therapy (ART) adherence vary, young adults are less likely to adhere because of psychosocial issues such as stigma, ART-related side effects as well as lack of access to treatment. Call for Life mHealth tool (C4LU), is a mobile phone- based technology that provides text messages or Interactive Voice Response (IVR) functionalities, through a web-interface and offers four modules including pill reminders, clinic visit reminders, health tips and symptom self-reporting support. Within a randomised control trial, we assessed perspectives and experiences of young adults living with human immunodeficiency virus towards the C4LU- system, with the objective to improve ART adherence among young people living with HIV with help of mHealth tool. OBJECTIVE To improve ART adherence among young people living with HIV through use of mHealth tool. METHODS This was an exploratory qualitative design at two study sites nested within an open label randomized controlled trial (RCT) entitled: “Improving outcomes in human immunodeficiency virus (HIV) patients using mobile phone based interactive software support “Call for Life study A total of 600 participants were randomly assigned 1:1 to either Standard of Care (SoC)- face-to-face counsellor adherence support or SoC plus mHealth call for life system (C4LU). C4LU uses Interactive voice response or text messages delivered via mobile phone. The qualitative study explored perspectives and experiences of young adults (18-24 years) towards the mHealth tool “C4LU”. A purposive sample of twenty-one vulnerable youth, seventeen from the intervention and four from the SoC arm were selected. We used semi-structured interviews to facilitate an in-depth exploration of experiences of young adults regarding C4LU-System. Thirteen in-depth interviews and one focus group discussion were conducted. The young adults were from four categories of population of interest that were targeted to be offered specialised care: young adults on PMTCT, switching to / or on second line ART, positive partners in a discordant relationship and initiating 1st line ART. Data was managed using Nvivo version 11 and analysed thematically. RESULTS C4LU-mHealth tool was perceived as an acceptable intervention for young adults. While on the system, participants reported: improvement in medication adherence, strengthened doctor /clinician -patient relationships, increased health knowledge through educative health tips. Appointment reminders and symptom reporting were singled out as beneficial because the system would address and manage the problems of forgetfulness, and stigma related issues. CONCLUSIONS The system was described as an acceptable and feasible strategy to improve ART adherence and retention among young adults in resource limited settings CLINICALTRIAL Trial Registration: ClinicalTrials.gov NCT 02953080


Medicine ◽  
2020 ◽  
Vol 99 (29) ◽  
pp. e21271
Author(s):  
Takeya Tsutsumi ◽  
Hidenori Sato ◽  
Tadashi Kikuchi ◽  
Kazuhiko Ikeuchi ◽  
Lay Ahyoung Lim ◽  
...  

2019 ◽  
Vol 71 (2) ◽  
pp. 353-362 ◽  
Author(s):  
Beatriz López-Centeno ◽  
Carlos Badenes-Olmedo ◽  
Ángel Mataix-Sanjuan ◽  
Katie McAllister ◽  
José M Bellón ◽  
...  

Abstract Background Drug–drug interactions (DDIs) that involve antiretrovirals (ARVs) tend to cause harm if unrecognized, especially in the context of comorbidity and polypharmacy. Methods A linkage was established between the drug dispensing registry of Madrid and the Liverpool human immunodeficiency virus (HIV) DDI database (January 2017–June 2017). Polypharmacy was defined as the use of ≥5 non-HIV medications, and DDIs were classified by a traffic-light ranking for severity. Results A total of 22 945 people living with HIV (PLWH) and 6 613 506 individuals without HIV had received medications. ARV regimens were predominantly based on integrase inhibitors (51.96%). Polypharmacy was higher in PLWH (32.94%) than individuals without HIV (22.16%; P < .001); this difference was consistently observed across all age strata except for individuals ≥75 years. Polypharmacy was more common in women than men in both PLWH and individuals without HIV. The prevalence of contraindicated combinations involving ARVs was 3.18%. Comedications containing corticosteroids, quetiapine, or antithrombotic agents were associated with the highest risk for red-flag DDI, and the use of raltegravir- or dolutegravir-based antiretroviral therapy was associated with an adjusted odds ratio of 0.72 (95% confidence interval, .60–.88; P = .001) for red-flag DDI. Conclusions Polypharmacy was more frequent among PLWH across all age groups except those aged ≥75 years and was more common in women. The detection of contraindicated medications in PLWH suggests a likely disconnect between hospital and community prescriptions. Switching to alternative unboosted integrase regimens should be considered for patients with risk of harm from DDIs.


2017 ◽  
Vol 21 (2) ◽  
Author(s):  
Farhana E. Suleman ◽  
Mahmood M.T.M. Ally

The reported prevalence of articular manifestations of human immunodeficiency virus (HIV) varies, but with sub-Saharan Africa accounting for almost 70% of the people living with HIV, this results in a considerable burden of disease in the region. The spectrum of clinical presentation described, includes articular pain syndrome, HIV-associated arthropathy and seronegative spondyloarthropathies, among others. This brief review serves to create awareness of the clinical and imaging presentation of this spectrum of disease as there is significant morbidity associated with these conditions if treatment is delayed.


2019 ◽  
Vol 18 (4) ◽  
pp. 14-24
Author(s):  
E. A. Bazykina ◽  
V. B. Turkutyukov ◽  
O. E. Trotsenko ◽  
I. O. Taenkova ◽  
L. A. Balakhontseva ◽  
...  

Relevance. HIV-infection continues to be one of the unsolved issues of modern healthcare. In the Russian Federation, an annual increase in the number HIV-infected people including co-infected with HIV and viral hepatitis is registered. This is associated with common transmission mechanisms of the diseases. Objective: to conduct a retrospective analysis of the main HIV-infection epidemiological indices that included prevalence of viral hepatitis B and C among people living with HIV in the Far Eastern Federal district during years 2006–2018. Materials and methods: the conducted retrospective epidemiological analysis was based on evaluation of materials provided by AIDS prevention and control regional centers as well as in the official statistical data form № 61 «Data on HIVinfected contingents». Analysis of the obtained data included parametric and nonparametric statistics. Results. A deterioration of the epidemic situation concerning HIV-infection with and without viral hepatitis B and C was registered in the Far Eastern Federal district. The fraction of HIV-positive people aged 40 years and older increased up to 24.68 ± 0.26% in 2018. Feminization of HIV-infected population was observed. The fraction of HIV-positive women increased from 32.30 ± 0.50 % in 2006 to 36.82 ± 0.29% in 2018. The fraction of sexual transmission mechanism of the HIV has increased during the observed period of time and totaled 40.60 ± 0.30% in 2018. This fact plays a significant part in the spread of HIV in the Far Eastern Federal district. Conclusion. The revealed tendencies indicate a necessity of changing the preventive measures strategy against HIV.


2015 ◽  
Vol 2 (1) ◽  
pp. 006-014
Author(s):  
Erni Setiyorini

Human Immunodeficiency Virus (HIV)is desease with high mortality and everyone have chancegot HIV. At Blitar HIV/AIDS prevalence increase since 2010. The incubation of HIV need long time tobecome AIDS. At this period PLWHA faced with physic, physichologic, sosial, environment problem andimpact to their quality of life. The purpose of this study was to describe quality of life PLWHA at physic,physichologic, sosial, environment dimension. Method: Research design was descriptive. Population ofthis study is PLWHA who receiving ARV at Cendana Clinic Ngudi Waluyo Wlingi Hospital. Samples 42respondent by using convenient sampling. Data collected at September 1st– 30, 2013 by questionaire.Result of this study in physic dimension much of them at good 16 peoples (38,1%), enough and less, eachof them 13 peoples (31%). Physhicology dimension at good and enough, each of them 20 peoples(47,6%) then at less 2 peoples (4,8%). Sosial dimension enough 25 peoples (59,5%), good 15 peoples(35,7%) and less 2 peoples (4,8%). Environment dimension enough 16 peoples (38,1%), good 15peoples (35,7%) dan kurang 11 orang (26,2%). It is suggested for nurse to implementation nursing careplan to PLWHA suitable with their quality of life dimension and enhance support to their sosial activity.


2020 ◽  
Vol 5 (1) ◽  
pp. 83
Author(s):  
Mugiarjo Mugiarjo

<div><em>Regarding the response to self-disclosure, a person needs to make an attribution in order to know whether the response is really an intention or just a diversion. This </em><em>article</em><em> </em><em>based on </em><em>qualitative methods. Data collect</em><em>ed by </em><em>observation,</em><em> </em><em>interview</em><em>, and documentation</em><em>. The results of this study indicate that </em><em>People Living With HIV/Aids (</em><em>PLWHA</em><em>)</em><em> carry out quite strict regulations by conducting an assessment first before disclosing their </em><em>Human Immunodeficiency Virus (</em><em>HIV</em><em>)</em><em> status. The response obtained after they opened the status to the significant others was attributed by. The basis of sincere acceptance and response, the stability of the relationship between PLWHA and significant others after opening the status can be maintained, even stronger. PLWHA rely heavily on the power of spirituality to be able to build themselves better. In addition, the ability to make peace with oneself over their circumstances also influenced by this spirituality. Appreciation of spirituality also indicate that their engagement with God strengthened. This strength is shown by their awareness of the meaning of life.</em></div>


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