Antipruritic therapy issues on background of skin xerosis

2021 ◽  
pp. 37-41
Author(s):  
L. S. Kruglova ◽  
E. V. Tipaeva

The relationship of xerosis with various skin diseases is very multifaceted, at the same time, xerosis can be the cause of the onset or aggravation of itching. Modern recommendations for the external treatment of chronic dermatoses, accompanied by xerosis and itching, imply two directions: direct therapeutic measures during an exacerbation and the use of dermatocosmetics adapted to certain symptoms.Material and methods. We observed 26 patients (mean age 38.7 ± 1.9 years with atopic dermatitis, eczema, psoriasis or pruritus, where xerosis was present in the clinical picture and pruritus was noted. All patients used topical drugs in accordance with the nosology, in as an adjuvant therapy – Neotanin Comfort Plus cream.Research results. In atopic dermatitis, the corneometry index increased by an average of 21%, with eczema – by 20%, with psoriasis – by 22%, with skin itching – by 12%. Transepidermal water loss decreased in atopic dermatitis by 19.8%, with eczema – by 22.8%, with psoriasis – by 21.8%, with pruritus – by 18.4% The value of the total BRS index decreased by more than two times.Conclusion. The use of Neotanin Comfort Plus cream in combination with topical drug therapy (GCS, multicomponent drugs) is highly effective and safe in patients with atopic dermatitis, eczema, psoriasis or pruritus, which makes it possible to recommend it for use in wide clinical practice.

Author(s):  
Tat'yana A. Rebeko

The study examines the relationship of non-adaptive types of coping with different forms of psychosomatic skin diseases (psoriasis and atopic dermatitis). The study involved 72 women, mean age is 37 (30 – control group (NORM), 25 – patients with atopic dermatitis (AD), 17 – patients with psoriasis (PS)). Based on published data, a theoretical hypothesis is put forward that the deformation of the early symbiotic bonds of the mother and baby (and the corresponding types of relationships with the mother) leads to the formation of a second skin and is a predictor of skin diseases. Empirical data on the similarity of the symptoms of the clinical picture of the disease and various forms of symbiosis deformity are presented. These forms are described through the metaphor of the mother's gaze – "one-sided" and "distorting". It is assumed that the "one-sided gaze" is associated with blood pressure, and the "distorting" one is associated with PS. Using nonparametric statistics methods (Kruskal-Wallis test), it is proved that non-adaptive coping in the AD and PS groups corresponds to two forms of symbiosis deformation.


Author(s):  
Jonathan Kimmelman

Many representations of clinical translation present it as a linear process by which bench discoveries are advanced into clinical practice. The present chapter offers a conceptual framework that highlights distinctive ethical aspects of clinical translation. The framework understands clinical translation as a process not so much as developing new treatments but rather generating evidence on how to use (and how not to use) new as well as old interventions. It also emphasizes attending to the relationship of different studies with each other and the importance of coordinating different studies with each other. The model presented here foregrounds the role of coordination in realizing societal objectives of clinical translation at minimal burden and cost for patients and study volunteers.


2014 ◽  
Vol 133 (2) ◽  
pp. AB196
Author(s):  
Gillian Bassirpour ◽  
Edward M. Zoratti ◽  
Ganesa Wegienka ◽  
Suzanne Havstad ◽  
Alexandra Sitarik ◽  
...  

2019 ◽  
Vol 26 (2) ◽  
pp. 911-924
Author(s):  
Mark J Rapoport ◽  
Carla Zucchero Sarracini ◽  
Benoit M Mulsant ◽  
Dallas P Seitz ◽  
Frank Molnar ◽  
...  

Clinicians face challenges in deciding which older patients with dementia to report to transportation administrators. This study used a qualitative thematic analysis to understand the utility and limitations of implementing a computer-based Driving in Dementia Decision Tool in clinical practice. Thirteen physicians and eight nurse practitioners participated in an interview to discuss their experience using the tool. While many participants felt the tool provided a useful ‘virtual second opinion’, specialist physicians felt that the tool did not add value to their clinical practice. Barriers to using the Driving in Dementia Decision Tool included lack of integration with electronic medical records and inability to capture certain contextual nuances. Opinions varied about the impact of the tool on the relationship of clinicians with patients and their families. The Driving in Dementia Decision Tool was judged most useful by nurse practitioners and least useful by specialist physicians. This work highlights the importance of tailoring knowledge translation interventions to particular practices.


2019 ◽  
Vol 91 (12) ◽  
pp. 75-83
Author(s):  
V V Fomin ◽  
T E Morosova ◽  
V V Tsurko

In recent years, the relationship of hyperuricemia and gout with a high risk of cardiovascular disease has been widely discussed. Therefore, it is important to systematically examine patients in order to diagnose comorbidities, among which cardiovascular disease and its complications occupy a leading place and consider mandatory treatment of patients with hyperuricemia and gout with high cardiovascular risk with lowering drugs, which fully reflects the provisions of the latest European recommendations for the management and treatment of patients with gout.


2021 ◽  
Vol Volume 17 ◽  
pp. 903-908
Author(s):  
Muhammad Asif Syed ◽  
Aneela Atta Ur Rahman ◽  
Muhammad Nadeem Shah Syed ◽  
Naveed Masood Memon

Blood ◽  
1949 ◽  
Vol 4 (8) ◽  
pp. 970-976 ◽  
Author(s):  
ALFRED P. FISHMAN ◽  
J. MURRAY KINSMAN

Abstract Seven patients with severe hypoplastic anemia were studied at an army Tropical Disease Center. Four of the 7 patients had concomitant dermatitis. The relationship of the prolonged administration of atabrine to the anemia and dermatitis is presented. A hematologic remission could not be induced by specific therapeutic measures. Four of the 7 cases recovered spontaneously.


2017 ◽  
Vol 114 (2) ◽  
pp. 166-175
Author(s):  
Mark E. Biddle

While a biblical doctrine of sin requires the honest and careful assessment of the complexity and plurality of the biblical witness,2 especially with regard to the relationship of the two Testaments, scholarship often draws lines of demarcation between the two Testaments too sharply. Ancient Israel’s priests devoted significant attention to the “objective” quality of wrong done as a pastoral problem, for example. Leviticus establishes that “unintentional sin” covers the whole gamut of behaviors short of willful sin that can result in terrible injury and harm. Indeed, the priests so consistently held the notion that wrong inheres in a situation, regardless of the intention of the actor, that they could use the language of sin to discuss skin diseases (Lev 14:1–32) and mold in houses (Lev 14:33–53). Israel’s priests did not speculate as to the precise point along the spectrum of willfulness and inadvertence at which one becomes morally culpable in the legal sense. Instead, their approach was much more pastoral: whatever the psychological and ethical dynamics preceding and underlying a wrong, the priests saw their role primarily in terms of healing, restoration, and restitution. Jesus and James expanded the priestly notion of sin as an objective reality to include intention as a category in the discussion of sin, but did not make it definitive of sin. Although the Gospels preserve no other discourse of Jesus even impinging on the subject of the concrete reality of sin, Jesus’ behaviors, especially instances when he healed without assigning blame or seeking repentance first, manifest his priestly concern for correcting inherent wrongness, for restoring rightness. Following Jesus, the priests’ view that any disorder threatens the harmony of the cultic community can supply useful and pertinent raw material for Christian theology and ethics today.


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