scholarly journals Anesthetic management of emergency and planned endovideoscopic gynecological operations in the context of the COVID-19 novel coronavirus infection pandemic (review of the problem)

2021 ◽  
pp. 53-57
Author(s):  
M. I. Neimark ◽  
S. A. Khaustova ◽  
Z. A. Titova ◽  
D. P. Epp
Keyword(s):  
Pain Relief ◽  
Anesthetic Management ◽  
Biomedical Literature ◽  
Clinical Indication ◽  
Cochrane Central Register ◽  
Narcotic Analgesics ◽  
Central Register ◽  
Inflammatory Drugs ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Purpose of the study. Extract original operational data containing information on the effect of non-steroidal anti-inflammatory drugs (NSAIDs) and the inclusion in the outcomes of the new coronavirus infection SARS-CoV‑19, descriptive analyzes and meta-analyzes, as in emergency and planned in gynecology, NSAIDs are used for the purpose of pain relief.Materials and methods. A systematic literature search was carried out to identify suitable studies in the electronic databases MEDLLINE, the Cochrane Central Register of Controlled Trials, the Chinese Biomedical Literature Database (CBM), domestic publications of the Russian information and analytical portal eLibrary.ru. The time horizon of publications on the problems of pain relief in women during endovideoscopic operations was 20 years. The search for publications in all languages on the use of NSAIDs in the conditions of SARS-CoV‑19 in all patient populations, regardless of gender, age, severity of the condition, was carried out for 2019–2021. The last search query is of 12/20/2021.Results and conclusions. The solution to a number of problems of anesthesia can be the refusal to use narcotic analgesics for endovideoscopic operations for female infertility. There is no clear clinical indication of the effect of NSAIDs on the risk of infection or an increase in the severity of SARS-CoV‑19 disease.

scholarly journals Effects of respiratory rehabilitation on patients with novel coronavirus (COVID-19) pneumonia in the rehabilitation phase: protocol for a systematic review and meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e039771 ◽  
Author(s):  
Feilong Zhu ◽  
Ming Zhang ◽  
Min Gao ◽  
Cheng Zeng ◽  
Dan Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Grey Literature ◽  
Mean Difference ◽  
Biomedical Literature ◽  
Cochrane Central Register ◽  
Continuous Variables ◽  
China National Knowledge Infrastructure ◽  
Novel Coronavirus ◽  
Respiratory Rehabilitation

IntroductionThe recent viral pneumonia caused by the COVID-19 has gained the attention of the people all over the world. We aim to investigate the effects of respiratory rehabilitation therapy on patients infected with the novel coronavirus by conducting a systematic review and meta-analysis.Methods and analysisThis systematic review and meta-analysis have been registered in the International Prospective Register of Systematic Reviews (PROSPERO). The PubMed, Embase, Web of Science, the Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang Data and Viper information databases will be searched from inception time to date without restricting research types to find relevant studies. We will also look into reference lists of relevant trials and reviews, and manually search grey literature, such as trial registries. Two reviewers will independently extract data and perform quality assessment of included studies. Review Manager V.5.3 (Cochrane Collaboration) and Stata V.16.0 software will be used to conduct this meta-analysis. The mean difference or standardised mean difference with 95% CIs is used in the computation of continuous variables to synthesise data.Ethics and disseminationEthical approval is not required due to the nature of this meta-analysis, which is based on published papers. The results of this systematic review and meta-analysis will be published in a peer-reviewed journal once we finish this study.PROSPERO registration numberCRD42020180214.

scholarly journals Use of Anti-Inflammatory Drugs interventions for the treatment of Muscle Soreness: a Systematic Review and Meta-analysis.

2020 ◽  
Author(s):  
Roberto Lohn Nahon ◽  
Anibal Monteiro de Magalhães Neto ◽  
Jaqueline Santos Silva Lopes ◽  
Aloa de Souza Machado ◽  
L. C. Cameron
Keyword(s):  
Systematic Review ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Significant Heterogeneity ◽  
Cochrane Central Register ◽  
Eligibility Criteria ◽  
Central Register ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Randomised Controlled

Abstract Objective: To investigate the effects of pharmacological interventions in the treatment of Delayed Onset Muscle Soreness (DOMS). Design: Systematic review and meta-analysis of randomised controlled clinical trials (RCTs). Data sources: The PubMed / MEDLINE, EMBASE, SPORTDiscus, Scielo and CENTRAL (Cochrane Central Register of Controlled Trials) databases were searched from the oldest records to August 3, 2020. Eligibility criteria: 1) Tue used a RCTs design; 2) Evaluate the effects of Steroidal or Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for treatment DOMS; and 3) Therapeutically used drugs, after exercise. Results: In total, 26 studies (patients = 934) were eligible for qualitative analysis on the treatment of DOMS. The results of the meta-analysis showed no superiority between the use or not of NSAIDs, in the improvement of late muscle pain, since statistically significant differences were not verified (21 studies, n= 955; SMD= 0.02; 95% CI -0.58, 0.63; p=0.94; I2=93%). The quality of the synthesized evidence was very low according to the criteria of Evaluation, Development and Evaluation of the Classification of Recommendations, associated with the significant heterogeneity among the included studies. Conclusion: The results demonstrate that the use of NSAIDs is not a superior treatment to the control / placebo on DOMS improvement. The variation between dose-response and exercise protocol used in the studies may have influenced the results. In addition, the high risk of identified bias characterizes limitation to be considered in profound interpretations.

scholarly journals Clinical Attributes and Electroencephalogram Analysis of Patients With Varying Alpers’ Syndrome Genotypes

2021 ◽  
Vol 12 ◽  
Author(s):  
Hua Li ◽  
Wei Wang ◽  
Xiaodi Han ◽  
Yujia Zhang ◽  
Lifang Dai ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Neurodegenerative Disorder ◽  
Clinical Phenotype ◽  
Intractable Epilepsy ◽  
High Amplitude ◽  
Biomedical Literature ◽  
Cochrane Central Register ◽  
Pathogenic Variants ◽  
Developmental Regression ◽  
Central Register

Alpers’ syndrome is an early inceptive neurodegenerative disorder with a poor prognosis, characterized by developmental regression, intractable epilepsy, and hepatic dysfunction. Candidate genes, such as POLG, PARS2, CARS2, FARS2, NARS2, and GABRB2 are distinguished and registered following research on large cohorts that portray the clinical phenotype in such patients using expanded access to whole-exome sequencing (WES). In this study, we aimed to better understand the electroencephalogram (EEG) characteristics and clinical phenotype of different genotypes of the Alpers’ syndrome, which are currently insufficiently studied. We conducted a study on seven patients with Alpers’ syndrome who received treatment in Beijing Children’s Hospital and had a detailed clinical EEG. Furthermore, a substantial literature search of the Chinese Biomedical Literature Database, PubMed, and Cochrane Central Register of Controlled Trials EMBASE was also conducted, which revealed a total of 22 reported cases between January 2008 to January 2021. We analyzed 29 cases of Alpers’ syndrome caused by different gene variants, of which 22 cases were related to POLG gene mutation and 7 cases were related to PARS2, CARS2, FARS2, NARS2, and GABRB2 gene mutation, and found that patients with distinctive pathogenic variants exhibited comparable phenotypes and similar EEG patterns. And we defined EEG characteristics found specifically in Alpers’ syndrome. Rhythmic high-amplitude delta with superimposed (poly) spikes (RHADS) is a characteristic EEG finding in the early stages of Alpers’ syndrome and is a kind of epileptic phenomenon, which can provide clues for the early diagnosis of the disease.

scholarly journals Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis

2020 ◽  
Author(s):  
Yuxi Li ◽  
Xiaobo Liu ◽  
Liuxue Guo ◽  
Juan Li ◽  
Dongling Zhong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
World Health ◽  
Cochrane Central Register ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Novel Coronavirus

Abstract Background A new type of coronavirus, novel coronavirus (COVID-19), is causing an increasing number of cases of pneumonia and was declared a Public Health Emergency of International Concern by the World Health Organization on 30 January 2020. The virus first appeared in Wuhan, China in late December 2019 and traditional Chinese herbal medicine is being used for its treatment. This systematic review and meta-analysis will assess studies of the effects of traditional Chinese herbal medicine in COVID-19 pneumonia. Methods We will search electronic databases including PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP) and Wanfang database using keywords related to COVID-19 and traditional Chinese herbal medicine. Reference lists of relevant trials and reviews will be searched. We will manually search grey literature, such as conference proceedings and academic degree dissertations, and trial registries. Two independent reviewers will screen studies (XL and DZ), extract data (YL and LG) and evaluate risk of bias (YL and DZ). Data analysis will be conducted using Review Manager software (version 5.3.5) and R software (version 3.6.1). Statistical heterogeneity will be assessed using a standard Chi-square test with a significance level of P < 0.10. Biases associated with study size (e.g. publication bias) will be investigated using funnel plots, the Egger 's test and Begg 's test and Trim and Fill analysis. Discussion This study will provide a high-quality synthesis of the effects of traditional Chinese herbal medicine for COVID-19. The use of traditional Chinese herbal medicine for treatment or prevention of these novel viral infections affecting the pneumonia will be investigated. Systematic review registration PROSPERO registration number: CRD42020168004

scholarly journals Traditional Chinese medicine for treating novel coronavirus (2019-nCoV) pneumonia: protocol for a systematic review and meta-analysis

2020 ◽  
Author(s):  
Yuxi Li ◽  
Xiaobo Liu ◽  
Liuxue Guo ◽  
Juan Li ◽  
Dongling Zhong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Meta Analysis ◽  
Grey Literature ◽  
Biomedical Literature ◽  
World Health ◽  
Cochrane Central Register ◽  
Academic Degree ◽  
Novel Coronavirus

Abstract Background: A new type of coronavirus, 2019 novel coronavirus (2019-nCoV), is causing an increasing number of cases of pneumonia and has been declared a Public Health Emergency of International Concern by the World Health Organization on 30 January 2020. The virus first appeared in Wuhan, China in late December 2019 and traditional Chinese medicine (TCM) is being used for its treatment. This systematic review and meta-analysis will assess studies of the effects of TCM in 2019-nCoV-infected pneumonia (NCIP).Methods: We will search electronic databases including PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP) and Wanfang database using keywords related to NCIP and TCM. Reference lists of relevant trials and reviews will be searched. We will manually search grey literature, such as conference proceedings and academic degree dissertations, and trial registries. Two independent reviewers will screen studies, extract data and evaluate risk of bias. Data analysis will be conducted using Review Manager software (version 5.3.5) and R software (version 3.6.1).Discussion: This study will provide a high-quality synthesis of the effects of TCM for NCIP. The use of TCM for treatment or prevention of these novel viral infections affecting the respiratory tract will be investigated.Systematic review registration: PROSPERO registration number: CRD42020168004

Experience in Applying Hyperbaric Oxygen Therapy Using Portable Pressure Chambers for the Treatment of Patients with the Novel Coronavirus Infection COVID-19

Biomeditsina ◽  
2020 ◽  
pp. 39-46
Author(s):  
A. S. Samoilov ◽  
Yu. D. Udalov ◽  
M. V. Sheyanov ◽  
A. V. Gholinsky ◽  
A. B. Litvinenko
Keyword(s):  
Oxygen Saturation ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Capillary Blood ◽  
Blood Hemoglobin ◽  
Patient Groups ◽  
Radiological Changes ◽  
Coronavirus Infection ◽  
Novel Coronavirus

This communication presents the experience of using mobile pressure chambers in patients with the confi rmed novel coronavirus infection in hospital settings. The obtained preliminary results indicate positive antihypoxic effects of hyperbaric oxygen therapy (HBO) applied in the form of increased saturation. After a session of HBO, patients demonstrated an increase in the oxygen saturation of capillary blood hemoglobin at the average level of 3.71 points. Differences between SatO2 levels prior to and following HBO treatment were signifi cant in the CT2, CT3 and CT4 groups (p0.05). As expected, the effi cacy of HBO in terms of the oxygen saturation of capillary blood hemoglobin was the greatest in the patient groups showing pronounced clinical and radiological changes in the lungs.

Review on Efficacy of Herbal Antiviral Drugs against COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1116-1121
Author(s):  
Pooja P. Thakre ◽  
Vinod Ade ◽  
Shweta Parwe
Keyword(s):  
Physical Contact ◽  
Research Articles ◽  
Herbal Drugs ◽  
Plant Origin ◽  
Respiratory Pathway ◽  
Traditional Medicines ◽  
The Past ◽  
Primary Health ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Coronavirus disease (CoViD-19) is an infection of the respiratory system caused due to various viruses affects the respiratory pathway, and it can spread from one person to another by coughing, sneezing or physical contact. Commonly include cough, cold, fever are the symptoms. Viral diseases increase worldwide concern, including emerging and chronic viruses. The invention of new anti-viral drugs from plants has implicit in the past. The Coronavirus disease 19 (COVID-19) caused due to severe acute respiratory syndrome, which is a transmittable and pathogenic viral infection. Several traditional medicines of plant origin having antimicrobial and anti-inflammatory properties some have been studied for their anti-viral properties and immune-modulating effects. Herbal drugs are now in massive requirement in the developing countries for primary health care not because of their economical but also for better civilising adequacy, improved compatibility with the human body and significantly fewer side effects. This review gives an overview of some critical traditionally used medicinal herbs with anti-viral properties—the literature regarding the drugs of this group, collected from Ayurveda classics. Research articles are collected from published material and discussed per therapeutic actions. Most of the Herbs are with Katu Rasa (pungent) and Ushna Virya (hot potency). They are indicated in diseases, viz. Kasa (cough), Shwas (asthma), Krumi (worm/ infection). Krumihara property drugs which are correlated with anti-viral action helps to prevent against Novel coronavirus infection.

Association and treatment of diabetes in patients affected by Covid-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1198-1201
Author(s):  
Syed Yasir Afaque
Keyword(s):  
Diabetes Mellitus ◽  
Prognostic Value ◽  
Heart Diseases ◽  
The Novel ◽  
The World ◽  
Treatment Of Diabetes ◽  
Coronavirus Infection ◽  
Composite Outcomes ◽  
Novel Coronavirus ◽  
The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

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