scholarly journals Perbandingan Gambaran Foto Toraks Pasien TB-HIV Dua dan Enam Bulan Pengobatan Anti-Tuberkulosis + Anti-Retroviral

2015 ◽  
Vol 1 (2) ◽  
pp. 91-98
Author(s):  
Edi Yanuarto Hidayat ◽  
Nasirun Zulqarnain ◽  
Muchlis Achsan Udji Sofro
Keyword(s):  
Internal Medicine ◽  
Developing Countries ◽  
Risk Factor ◽  
Antiretroviral Therapy ◽  
Observational Study ◽  
Chest Radiographs ◽  
Health Issues ◽  
Hiv Patients ◽  
Latent Tb ◽  
Radiographic Improvement

Background: Tuberculosis (TB) remains a global health issues and mostly located in developing countries. As cases of HIV/AIDS increase every year, it is estimated that TB cases also increase. TB is the leading cause of death in people with HIV and HIV infection, and became the biggest risk factor in the conversion of latent TB cases to become active TB. Radiographic manifestation of TB in AIDS patients depends on antiretroviral therapy (ART).Materials and Methods: This is an observational study which compares 2 and 6 months chest radiographs from TB-HIV patients with anti-TB drugs+ART in 24 adults patients with TB-HIV in the Internal Medicine Polyclinic and Ward at Dr. Kariadi Hospital and BKPM Semarang.Result: Most patients were male with 19 subjects (79.2%). The large stage group based on the proportion of AIDS cases is 20-29 years (45.84%). After 6 months of anti-TB drugs+ART there were radiographic improvement in consolidation, cavitation, lymphadenopathy and pleural e?usion. Wilcoxon Signed Ranks Test showed signifcant changes in consolidation and lymphadenopathy between 2 and 6 months of anti-TB drugs+ART, but no signifcant changes in cavity and pleural e?usion.Discussion: At 6 months chest radiographs examination, not all patients with anti-TB drugs+ART show radiographic improvement. Therefore, the decision to stop TB therapy in HIV patients in 6 months time seems inadequate.Conclusion: There are signifcant change between 2 and 6 months of anti-TB drugs+ART with radiographic improvement are consolidation and lymphadenopathy.

scholarly journals Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

2014 ◽  
Vol 2 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Gustavo Romero‐Velez ◽  
Andrés Lisker‐Cervantes ◽  
Christian I. Villeda‐Sandoval ◽  
Mariano Sotomayor de Zavaleta ◽  
Daniel Olvera‐Posada ◽  
...  
Keyword(s):  
Risk Factor ◽  
Erectile Dysfunction ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Main Risk Factor ◽  
Hiv Patients ◽  
Highly Active

Three different patterns of CD4 recovery in a cohort of Chinese HIV patients following antiretroviral therapy – a five-year observational study

2014 ◽  
Vol 26 (11) ◽  
pp. 803-809 ◽  
Author(s):  
Claire M Naftalin ◽  
Ngai Sze Wong ◽  
Denise PC Chan ◽  
Ka Hing Wong ◽  
Daniel D Reidpath ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Observational Study ◽  
Hiv Patients

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

scholarly journals The CONFINE (Comorbidities and Outcome iN patients with chronic heart Failure: a study in INternal mEdicine units) study: a new epidemiologic observational study on heart failure in the internal medicine departments in Italy

2013 ◽  
pp. 57-64
Author(s):  
P. Biagi
Keyword(s):  
Internal Medicine ◽  
Heart Failure ◽  
Observational Study ◽  
Inflammatory Diseases ◽  
Correct Diagnosis ◽  
Cognitive Disorders ◽  
Epidemiological Data ◽  
Chronic Kidney Failure ◽  
Chronic Obstructive ◽  
Quality Life

BACKGROUND The burden of heart failure (HF) is enormous and its prevalence increases sharply with age. It has been estimated that heart failure affects up to 3% of the general population and 10% of the elderly. It contributes to hospital admission for most of them, mainly elder adults (admitted in internal medicine units) with more than one comorbidity, cognitive disorders, impairment and so on. Despite the increasing prevalence of heart failure, its exact incidence and prevalence remain largely unknown and probably underestimated due to a lack of accurate epidemiological data and difficulties associated with comorbidities and correct diagnosis: over 40% of recurrent hospitalization causes, either cardiac or extracardiac, cannot be determined due to the lack of data. AIM OF THE STUDY The objective of this study estimated the prevalence and the primary care burden associated with comorbidities in internal medicine units. METHOD The design: a longitudinal multicentric observational study using spot analysis three data sheets were filled in during the hospital stay according to three crucial moments: enrolment (“the index day”), admission and discharge. Will be analyzed the following primary outcomes: total and cardiovascular mortality, intensive unit care admission, recurrent cardiovascular disorders, length of stay, hospital readmission, changes in activities of daily living, need for care. Second outcomes: clinical, therapeutic, instrumental and laboratory changes during the admission process. Deep analysis of the following comorbidities will be also taken into account: acute and chronic kidney failure, anaemia, chronic obstructive pulmonary disease, muscle loss, nutritional status, cirrhosis of the liver, neoplasms, blood cell disorders, chronic inflammatory diseases. Further evalutation items: cognitive impairment, self-sufficiency and perception of quality life.

scholarly journals Hematological Profile of HIV-Infected Patients on First-Line Highly Active Antiretroviral Therapy and Its Correlation With CD4 Count

2021 ◽  
Author(s):  
John Jospeh Diamond Princy ◽  
Kshetrimayum Birendra Singh ◽  
Ningthoujam Biplab ◽  
Ningthoukhongjam Reema ◽  
Rajesh Boini ◽  
...  
Keyword(s):  
Platelet Count ◽  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Highly Active Antiretroviral Therapy ◽  
Cd4 Count ◽  
Total Leukocyte Count ◽  
Hiv Patients ◽  
Positive Correlation ◽  
Highly Active ◽  
The Mean

Abstract Introduction Human immunodeficiency virus (HIV) infection is a state of profound immunodeficiency. Disorders of hematopoietic system are a common but often overlooked complication of HIV infection. This can manifest at any stage of the disease but more commonly in the advanced stage with low CD4 count. Anemia is the most common hematological abnormality in HIV patients and prevalence ranges from 1.3 to 95%. As HIV disease progresses, the prevalence and severity of anemia also increase. Hence, this study was undertaken to assess the hematological parameters of HIV-infected patients on highly active antiretroviral therapy (HAART) at different treatment durations with the hope to improve the HAART outcome in HIV patients and its correlation with CD4 count. Methods This prospective longitudinal study enrolled 134 HIV-infected patients admitted to or attending the OPD in the Department of Medicine or Antiretroviral Therapy (ART) Center (Center of Excellence), Regional Institute of Medical Sciences (RIMS), Imphal, Manipur, from 2018 to 2020. Complete hemogram, CD4 count, and other related-blood investigations were studied. Results The mean age of the study population was 39.9 ± 11.04 years. Of the 134 patients, 75 (56%) were males and 59 (44%) were females. Twelve (9%) patients had a history of injecting drug use (IDU). TLE (tenofovir, lamivudine, efavirenz) regimen was started on 112 (83.6%) patients and the majority of them (69/134 [51.5%]) had a CD4 count of 200 to 499 cells/mm3, which increased significantly 6 months after HAART to 99 to 1,149 cells/mm3, with a mean of 445 ± 217 cells/mm3. There were significant improvements in hemoglobin (Hb) levels, total leukocyte count (TLC), absolute neutrophil count (ANC), and absolute lymphocyte count (ALC) after HAART indicating a positive correlation with CD4 count (p < 0.05). Thrombocytopenia was observed higher after HAART when compared to baseline. There was a positive correlation between platelet count and CD4 count. However, the mean corpuscular volume (MCV) and erythrocyte sedimentation rate (ESR) had a negative correlation with CD4 count. Conclusion The study inferred a strong positive correlation between CD4 and Hb levels, TLC, ANC, ALC, and platelet count after HAART with improvement in these values as CD4 count increases. Specific treatment intervention based on the changes in the immunohematological profile trends can help prevent most of the adverse effects on HIV patients in our community.

scholarly journals Is ventricular arrhythmias the end for all conditions ?

2021 ◽  
Author(s):  
Ahmet Goktug Ertem ◽  
Mehmet Akif Erdol ◽  
Koray Demirtas ◽  
Sefa Unal ◽  
Mustafa Karanfil ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Risk Factor ◽  
Antiretroviral Therapy ◽  
Ventricular Arrhythmias ◽  
Combination Antiretroviral Therapy ◽  
T Wave ◽  
Medical Status ◽  
Immunodeficiency Virus ◽  
Duration Of Disease ◽  
Severity Of The Disease

Dear Editor, We read the article entitled “Abnormal Dispersion of Ventricular Repolarization as a Risk Factor in Patients with Human Immunodeficiency Virus: Tp-e Interval, Tp-e/QTc Ratio” by Unal Evren et al. with interest[1]. The authors evaluated the changes in Tp-e interval, Tp-e/QT and Tp-e/corrected QT (QTc) ratios, and traditional electrocardiographic features of electrical dispersion in adults infected with Human Immunodeficiency Virus (HIV) and their study revealed that the cTp-e interval, Tp-e/QT and Tp-e/QTc ratios were prolonged and correlated to the severity of the disease in HIV-infected patients. Previous studies have revealed that the Tp–e interval, the Tpeak-Tend interval (Tpe), the interval from the T-wave peak to the end of the T wave, has been related to arrhythmogenesis, is specified as an index of totaldispersion of repolarization[2]. Prolonged Tp–e interval is predictable for ventricular arrhythmias and mortality [3]. Unal et al. showed that HIV-infected patients receiving combination antiretroviral therapy (cART) were associated withlonger Tp–e interval and Tp–e/QTc ratio and correlated positively with the duration of disease and the electrophysiologicalabnormalities, and negatively with CD4 count[4]. There were no informations about medical status of patients with HIV, duration of the disease and why hsCRP is higher in patients’ group. The patients were in active phases of infection. We think that these are important datas for results of the study. We thank the authors for adding this article to the literature

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