Eosinophilic gastrointestinal diseases and food protein-induced enterocolitis syndrome

Statistical data of livestock for 30 years is reflected in the article. Author used the materials of the state veterinary reporting. A comparative analysis of the number, incidence and death rate of adult animals and young cattle for two five-year periods (2001-2005 and 2014-2018). the data of the analysis of veterinary statistical reports for 2018 on the specific weight of the large horned cattle and age dynamics of calves in farms of the Vologda region are shown. A significant decrease in livestock of the large horned cattle by 56.3% (from 1990 to 2018) is shown in the analysis of the data. Over the five years 2014-2018, there was a decrease in the number of the large horned cattle by 31.3%, the birth rate of calves - by 26.2%, and the incidence of calves - by 12.3% and the mortality rate decreased by 3.3%. Despite the decline in the number of livestock, in 2018 there is a high incidence of animal diseases (49.6%). The highest incidence rate was observed among calves under 10 days of age 43.3%, 31.7% - from 11 to 30 days, 15.8% - from one to three months, 6.5% - from three to six months and 2.7% - from 6 to 12 months. Of the total number of sick calves in 2018, 63.2% had gastrointestinal diseases, and death for this reason is 49.6% of the total number of victims. Respiratory diseases affect 21.8% of young animals, and death due to respiratory diseases is 18.2%. Analysis of statistical data showed that, despite the complex of veterinary and sanitary measures, the incidence and death of calves remain at a high level. This can be explained by delayed diagnosis and low therapeutic effectiveness in gastrointestinal and respiratory diseases of cattle.

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Probiotics in gastroenterology – from a different angle

Orvosi Hetilap ◽

10.1556/oh.2013.29547 ◽

2013 ◽

Vol 154 (8) ◽

pp. 294-304 ◽

Cited By ~ 2

Author(s):

György Miklós Buzás

Keyword(s):

Side Effects ◽

Beneficial Effect ◽

Analytical Data ◽

Well Being ◽

Gastrointestinal Diseases ◽

Convincing Evidence ◽

Probiotic Treatment ◽

History Of ◽

Irritable Bowel

After a short overview of the history of probiotics, the author presents the development of human intestinal microflora based on the newest genetic data and the microbiological features of main probiotics. The indications of probiotic administration have been defined and extended in recent years. The author reviews significant results of probiotic treatment in some gastrointestinal diseases based on meta-analytical data. Probiotics are useful in preventing and treating diarrhoea caused by antibiotics and Clostridium difficile caused diarrhoea. In the treatment of Helicobacter pylori infection, preparations containing certain Lactobacillus,Bifidobacterium strains or Saccaromyces boulardii could enhance by 5–10% the rate of successful eradication and reduce the incidence and severity of the side effects. Some symptoms of irritable bowel syndrome and thus the quality of life can be improved by probiotics. Their beneficial effect in ulcerative colitis was proven, while in Crohn’s disease has not yet been defined. The use of probiotics is not included in guidelines, with the exception of the Maastricht IV/Florence consensus. For each disease it is advisable to use probiotics containing strains only with proven beneficial effect. The efficiency of preparations containing mixed strains has not yet been properly investigated. The author reviews the rare but potentially serious side effects of probiotics. In Hungary, there are many probiotic preparations available which can be purchased in pharmacies without prescription: their use is more empirical than evidence-based. The European Food Safety Authority has recently rejected claims for probiotics to be classed as medicines given the lack of convincing evidence on the effects of probiotics on human health and well-being. Clearly, further research is needed to collect evidence which could be incorporated into the international guidelines. Orv. Hetil., 2013, 154, 294–304.

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Food Protein Induced Enterocolitis Syndrom. Auch bei gestillten Säuglingen?

10.26226/morressier.57bc22f3d462b80296c9ae8b ◽

2016 ◽

Author(s):

Thomas Pachtner

Keyword(s):

Food Protein

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Current updates on COVID-19 - A review

International Journal of Novel Trends in Pharmaceutical Sciences ◽

10.26452/ijntps.v10i1.1141 ◽

2020 ◽

Vol 10 (1) ◽

pp. 1-8

Author(s):

Ghotekar D S ◽

Vishal N Kushare ◽

Sagar V Ghotekar

Keyword(s):

World Health Organization ◽

Common Cold ◽

Respiratory Diseases ◽

Gastrointestinal Diseases ◽

Hubei Province ◽

World Health ◽

The World ◽

The Common ◽

Novel Coronavirus ◽

Health Organization

Coronaviruses are a family of viruses that cause illness such as respiratory diseases or gastrointestinal diseases. Respiratory diseases can range from the common cold to more severe diseases. A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019. The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) a pandemic. A global coordinated effort is needed to stop the further spread of the virus. A novel coronavirus (nCoV) is a new strain that has not been identified in humans previously. Once scientists determine exactly what coronavirus it is, they give it a name (as in the case of COVID-19, the virus causing it is SARS-CoV-2).

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TECHNOGENIC LOAD OF THE PRODUCTION ENVIRONMENT AND ITS IMPACT ON THE MICROBIOTA OF THE HUMAN BODY

Bulletin Biomedicine and sociology ◽

10.26787/nydha-2618-8783-2020-5-4-54-59 ◽

2020 ◽

pp. 54-59

Author(s):

Bugero N.V. ◽

Aleksandrova S.M.

Keyword(s):

Bacterial Flora ◽

Gastrointestinal Diseases ◽

Biological Properties ◽

Health State ◽

Production Environment ◽

Fecal Matter ◽

Manufacturing Plants ◽

Mucous Membranes ◽

Industrial Health ◽

Overall Resistance

Foundries in manufacturing plants are characterized by hazardous working conditions. The paper makes an assessment of industrial health hazards, identifies groups of diseases dominant among the examined individuals. It is clear that gastrointestinal diseases make the largest percentage. The effect of destabilizing industrial factors that lead to the intestinal biome restructuring, help reduce the dominant microorganism’s group and increase opportunistic flora has been determined. The severity of this indicator correlates with professional working experience. Along with the fecal matter bacterial flora of the examined people, the protozoa that belong to the parasitic group (blastocysts, lamblia, amoeba) were identified, and Blastocystis spp. has the largest proportion. The biological properties of blastocysts were studied exemplified by anticarnosine activity (AcrA), which allows them to colonize the intestinal mucous membranes and helps displace obligate symbiotes against the decrease in the overall resistance of the macroorganism. The data obtained make it possible to forecast human health state under the conditions of anthropogenic-disturbed territories and plan measures to improve and protect workers’ health.

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ANTICYTOKINE ACTIVITY OF THE PROTOZOA BLASTOCYSTIS SPP

Bulletin Biomedicine and sociology ◽

10.26787/nydha-2618-8783-2020-5-4-44-48 ◽

2020 ◽

pp. 44-48

Author(s):

Bugero N.V. ◽

Ilyina N.A. ◽

Aleksandrova S.M.

Keyword(s):

Gastrointestinal Tract ◽

Gastrointestinal Diseases ◽

Control Group ◽

Ulcer Disease ◽

Cytokine Balance ◽

High Prevalence ◽

Blastocystis Spp ◽

High Level ◽

Eukaryotic Organisms ◽

High Degree

In addition to the classical pathogens, which are well understood and well identified, new pathogens with the potential to spread epidemiologically are being identified. Some of these little-known organisms are the simplest Blastocystis spp. blastocystostosis. The clinical significance of Blastocystis spp. and its pathogenicity are still under discussion. This parasite belongs to a group of single-celled eukaryotic organisms living in the colon of the human intestine. Blastocystis spp. is known to be found both in people with reduced immune status and in individuals without any clinical manifestation. It has been established that a sufficiently high degree of invasiveness is observed in persons with gastrointestinal tract diseases, dermatosis, allergic reactions, in patients with carriers of the human immunodeficiency virus, etc. Possessing persistence factors, protozoa blastocysts contribute to the inactivation of host defensive mechanisms, providing a stable anthogonistic effect. In recent years, many works have been devoted to the characteristics of the persistent properties of Blastocystis spr., however, individual properties of blastocysts, in particular, anticytokine activity (ACA), have not yet been studied. In this regard, the work studied the anticytokine activity of microorganisms isolated from healthy subjects and patients with gastrointestinal tract diseases. A high prevalence of the studied characteristic in the subjects was shown. The expression of anticytokine activity in the obtained isolates of blastocysts was the highest in the group of persons with gastric ulcer disease, which decreased in the order of duodenal ulcer, chronic cholecystitis, chronic gastritis, etc. The data obtained in this work on the high level of ACA expression in blastocyst isolates obtained from individuals with gastrointestinal diseases as compared with the control group enables to conclude that their exometabolites may influence the local cytokine balance [1], which supports the inflammatory process.

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