scholarly journals Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

2021 ◽  
Vol 9 ◽  
Author(s):  
Pedro J. Hernando ◽  
Simone Dedola ◽  
María J. Marín ◽  
Robert A. Field

Carbohydrate-coated nanoparticles—glyconanoparticles—are finding increased interest as tools in biomedicine. This compilation, mainly covering the past five years, comprises the use of gold, silver and ferrite (magnetic) nanoparticles, silicon-based and cadmium-based quantum dots. Applications in the detection of lectins/protein toxins, viruses and bacteria are covered, as well as advances in detection of cancer cells. The role of the carbohydrate moieties in stabilising nanoparticles and providing selectivity in bioassays is discussed, the issue of cytotoxicity encountered in some systems, especially semiconductor quantum dots, is also considered. Efforts to overcome the latter problem by using other types of nanoparticles, based on gold or silicon, are also presented.

2003 ◽  
Vol 773 ◽  
Author(s):  
Xiaohu Gao ◽  
Shuming Nie ◽  
Wallace H. Coulter

AbstractLuminescent quantum dots (QDs) are emerging as a new class of biological labels with unique properties and applications that are not available from traditional organic dyes and fluorescent proteins. Here we report new developments in using semiconductor quantum dots for quantitative imaging and spectroscopy of single cancer cells. We show that both live and fixed cells can be labeled with multicolor QDs, and that single cells can be analyzed by fluorescence imaging and wavelength-resolved spectroscopy. These results raise new possibilities in cancer imaging, molecular profiling, and disease staging.


1988 ◽  
Vol 27 (1) ◽  
pp. 81-83
Author(s):  
Nadeem A. Burney

Its been long recognized that various economies of the world are interlinked through international trade. The experience of the past several years, however, has demonstrated that this economic interdependence is far greater than was previously realized. In this context, the importance of international economic theory as an area distinct from general economics hardly needs any mentioning. What gives international economic theory this distinction is international markets for some goods and effects of national sovereignty on the character of economic activity. Wilfred Ethier's book, which incorporates recent developments in the field, is an excellent addition to textbooks on international economics for one- or twosemester undergraduate courses. The book mostly covers standard topics. A distinguishing feature of this book is its detailed analysis of the flexible exchange rates and a discussion of the various approaches used for their determination. Within each chapter, the author has extensively used facts, figures and major events to clarify the concepts in the light of the theoretical framework. The book also discusses, in a fair amount of detail, the existing international monetary system and the role of various international organizations.


2018 ◽  
Vol 27 (03) ◽  
pp. 129-134 ◽  
Author(s):  
B. M. Holzapfel ◽  
F. Jakob ◽  
A. A. Kurth ◽  
G. Maier ◽  
K. Horas

SummaryVitamin D deficiency is a global health problem of enormous and increasing dimensions. In the past decades, numerous studies have centered on the role of vitamin D in the pathogenesis and course of many diseases including several types of cancer. Indeed, vitamin D has been widely acknowledged to be involved in the regulation of cell proliferation, differentiation and apoptosis in numerous cancer cells. While the full range of molecular mechanisms involveld in cancer cell growth and progression remains to be elucidated, recent research has deepened our understanding of the processes that may be affected by vitamin D or vitamin D deficiency.In this review, we consider the properties of bone that enable cancer cells to grow and thrive within the skeleton, and the role of vitamin D and the vitamin D receptor in the process of primary and secondary cancer growth in bone.


2008 ◽  
Vol 16 (3) ◽  
pp. 355-371 ◽  
Author(s):  
Petr Kopecký ◽  
Gerardo Scherlis

Party patronage is generally associated with social, economic and political underdevelopment, and is hence seen as largely irrelevant in the context of contemporary European politics. In this article, we argue to the contrary, proposing that patronage reappears on the stage of European politics as a critical organizational and governmental resource employed by political parties to enhance their standing as semi-state agencies of government. In order to illustrate our main contention, we first define party patronage, disentangling it from other notions of political particularism that are often used synonymously in the literature. Second, we provide a brief overview of the literature on the past and present of patronage practices in Europe, arguing that rather than declining, patronage is still likely to be a relevant feature of contemporary party politics in Europe. Finally, we analyse the role of party patronage in the light of recent developments in several European countries, identifying three distinct patterns of patronage practices in the region.


2007 ◽  
Author(s):  
Bakhysh Bairamov ◽  
Vladimir Toporov ◽  
Farid Bayramov ◽  
Vladislav Lanzov ◽  
Mitra Dutta ◽  
...  

Author(s):  
W. Scott Frame ◽  
Larry Wall ◽  
Lawrence J. White

Financial intermediation has changed dramatically over the past thirty years, due in large part to technological change. The chapter first describes the role of the financial system in a modern economy and how technological change and financial innovation can affect social welfare. We then survey the empirical literature relating to several specific financial innovations, broadly categorized as new production processes, new products or services, or new organizational forms. In each case, we also include examples of significant FinTech innovations that are transforming various aspects of banking. Drawing on the literature on innovations from the 1990s and 2000s informs what we might expect from recent developments.


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