scholarly journals Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira

2018 ◽  
Vol 8 ◽  
Author(s):  
Haritha Adhikarla ◽  
Elsio A. Wunder ◽  
Ariel E. Mechaly ◽  
Sameet Mehta ◽  
Zheng Wang ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Signaling System ◽  
Pathogenic Leptospira ◽  
Global Gene Regulation

scholarly journals Computational modelling unravels the precise clockwork of cyanobacteria

2018 ◽  
Vol 8 (6) ◽  
pp. 20180038 ◽  
Author(s):  
Nicolas M. Schmelling ◽  
Ilka M. Axmann
Keyword(s):  
Gene Expression ◽  
Gene Regulation ◽  
Circadian Clock ◽  
Environmental Changes ◽  
Regulation Of Gene Expression ◽  
Computational Modelling ◽  
Circadian Clocks ◽  
Fitness Advantage ◽  
Fundamental Part ◽  
Global Gene Regulation

Precisely timing the regulation of gene expression by anticipating recurring environmental changes is a fundamental part of global gene regulation. Circadian clocks are one form of this regulation, which is found in both eukaryotes and prokaryotes, providing a fitness advantage for these organisms. Whereas many different eukaryotic groups harbour circadian clocks, cyanobacteria are the only known oxygenic phototrophic prokaryotes to regulate large parts of their genes in a circadian fashion. A decade of intensive research on the mechanisms and functionality using computational and mathematical approaches in addition to the detailed biochemical and biophysical understanding make this the best understood circadian clock. Here, we summarize the findings and insights into various parts of the cyanobacterial circadian clock made by mathematical modelling. These findings have implications for eukaryotic circadian research as well as synthetic biology harnessing the power and efficiency of global gene regulation.

scholarly journals Role of Corynebacterium glutamicum sprA Encoding a Serine Protease in glxR-Mediated Global Gene Regulation

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e93587 ◽  
Author(s):  
Eun-Ji Hong ◽  
Joon-Song Park ◽  
Younhee Kim ◽  
Heung-Shick Lee
Keyword(s):  
Gene Regulation ◽  
Corynebacterium Glutamicum ◽  
Serine Protease ◽  
Global Gene Regulation

scholarly journals A high-resolution network model for global gene regulation in Mycobacterium tuberculosis

2014 ◽  
Vol 42 (18) ◽  
pp. 11291-11303 ◽  
Author(s):  
Eliza J.R. Peterson ◽  
David J. Reiss ◽  
Serdar Turkarslan ◽  
Kyle J. Minch ◽  
Tige Rustad ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Mycobacterium Tuberculosis ◽  
High Resolution ◽  
Network Model ◽  
Global Gene Regulation

scholarly journals General transcription factor specified global gene regulation in archaea

2007 ◽  
Vol 104 (11) ◽  
pp. 4630-4635 ◽  
Author(s):  
M. T. Facciotti ◽  
D. J. Reiss ◽  
M. Pan ◽  
A. Kaur ◽  
M. Vuthoori ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Transcription Factor ◽  
General Transcription Factor ◽  
Global Gene Regulation
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