scholarly journals Feminizing Hormone Therapy Prescription Patterns and Cardiovascular Risk Factors in Aging Transgender Individuals in Australia

2021 ◽  
Vol 12 ◽  
Author(s):  
Matthew I. Balcerek ◽  
Brendan J. Nolan ◽  
Adam Brownhill ◽  
Peggy Wong ◽  
Peter Locke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Hormone Therapy ◽  
Cardiovascular Risk Factors ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Age Group ◽  
Median Dose ◽  
Cross Sectional ◽  
Transdermal Estradiol

ContextThe safety and efficacy of feminizing hormone therapy in aging transgender (trans) individuals is unclear. Current recommendations suggest transdermal estradiol beyond the age of 45 years, especially if cardiometabolic risk factors are present.ObjectiveTo evaluate feminizing hormone therapy regimens and cardiovascular risk factors in aging trans individuals.DesignRetrospective cross-sectional analysis.SettingPrimary care and endocrine specialist clinic in Melbourne, Australia.ParticipantsTrans individuals on feminizing therapy for ≥6 months.Main Outcomes MeasuresFeminizing hormone regimens and serum estradiol concentrations by age group: (a) ≥45 years, (b) <45 years, and prevalence of cardiometabolic risk factors in individuals ≥45 years.Results296 individuals were stratified by age group: ≥45 years (n=55) and <45 years (n=241). There was no difference in median estradiol concentration between groups (328 nmol/L vs. 300 nmol/L, p=0.22). However, there was a higher proportion of individuals ≥45 years treated with transdermal estradiol (31% vs. 8%, p<0.00001). Of those treated with oral estradiol, the median dose was lower in the ≥45 years group (4mg vs. 6mg, p=0.01). The most prevalent cardiometabolic risk factor in the ≥45 years group was hypertension (29%), followed by current smoking (24%), obesity (20%), dyslipidaemia (16%) and diabetes (9%).ConclusionsA greater proportion of trans individuals ≥45 years of age were treated with transdermal estradiol. Of those who received oral estradiol, the median dose was lower. This is important given the high prevalence of cardiometabolic risk factors in this age group, however cardiovascular risk management guidelines in this demographic are lacking.

scholarly journals Dyslipidemia and its Relationship with Cardiovascular Risk Factors in a Selected Population of Siliguri City, West Bengal, India.

2013 ◽  
Vol 5 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Ritam Banerjee ◽  
Sharmistha Bhattacherjee ◽  
Kuntala Ray ◽  
Jayanta Kumar Roy ◽  
Saikat Datta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
West Bengal ◽  
Medical Science ◽  
Cross Sectional Study ◽  
Dietary Fats ◽  
Age Group ◽  
Chi Square ◽  
Cross Sectional

Background: Dyslipidemia, one of the classical Framingham risk factors of cardiovascular diseases, accounts significantly to the rise of non communicable diseases in India. Urbanization, along with greater consumption of dietary fats and decreased physical activity, has led to an increase in this problem manifold. Objectives: To determine the prevalence of dyslipidemia among urban adults of Siliguri city, West Bengal and to identify the cardio-vascular risk factors associated with it. Methods: This descriptive, cross-sectional study was carried out among the 226 adults aged ≥20yrs in an urban area of Siliguri city, West Bengal, India. Data was collected by detailed history and physical examination; biochemical measurements were done using standards procedures. Dyslipidemia was defined by the presence of one or more than one abnormal serum lipid concentration. Statistical analysis was done using chi-square test, t test and logistic regression analysis using SPSS 20 software (Chicago, IL, USA). Results: Dyslipidemia was prevalent among 78.4 % of the total study subjects. Dyslipidemia was more in males than in females & in both males and females it was more prevalent in the age group 40 -59 years than in any other age group. It was associated with higher odds of major cardiovascular risk factors like hypertension, hyperglycemias, and tobacco use. Conclusion: Dyslipidemia remains a significant and growing problem in this part of the country. The reduction in the disease burden will require changes in life style as well as in national policies. DOI: http://dx.doi.org/10.3126/ajms.v5i1.8474 Asian Journal of Medical Science Vol.5(1) 2014 pp.1-8

scholarly journals Association between Diabetes and Cognitive Function among People over 45 Years Old in China: A Cross-Sectional Study

2019 ◽  
Vol 16 (7) ◽  
pp. 1294 ◽  
Author(s):  
Li Zhang ◽  
Jiao Yang ◽  
Zhangyi Liao ◽  
Xiaomeng Zhao ◽  
Xuefeng Hu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cardiovascular Risk ◽  
Episodic Memory ◽  
Cardiovascular Risk Factors ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Status

Objectives: The aim of this study is to identify the relationship between diabetes status including characteristics of diabetes and cognition among the middle-aged and elderly population (≥45 years) in China. Methods: A sample of 8535 people who participated in the China Health and Retirement Longitudinal Study (CHARLS) from June 2011 to March 2012 was analyzed. Two cognitive domains including episodic memory and executive function were measured through questionnaires. People were classified into four groups: no diabetes, controlled diabetes, untreated diabetes, treated but uncontrolled diabetes. Weighted multiple regression model was conducted to explore the association between diabetes and cognition in full sample as well as three different age groups (45–59, 60–74, ≥75). Adjustments were made for demographics and cardiovascular risk factors. Results: After adjusting several covariates, untreated diabetes (β = −0.192, p < 0.05) was significantly associated with episodic memory. In the age group of 45–69 years, untreated diabetes (β = −0.471, p < 0.05) and HbA1c level (β = −0.074, p < 0.05) were significantly associated with episodic memory. When adjusting for cardiovascular risk factors, all correlations were non-significant. Conclusion: The cross-sectional study suggests that untreated diabetes and HbA1c are the potential risk factor for cognitive impairment, and these associations are more significant in the age group of 45–59 years old. Cardiovascular factors are important mediating factors in the pathway between diabetes and cognitive impairment. More longitudinal studies are needed to confirm these associations.

Daily intake of macronutrients and energy in childhood and its association with cardiometabolic risk factors in Colombians

2020 ◽  
Vol 33 (12) ◽  
pp. 1569-1576
Author(s):  
Lyda Z. Rojas ◽  
Edna M. Gamboa-Delgado ◽  
Doris C. Quintero-Lesmes
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiometabolic Risk ◽  
Linear Regression Analysis ◽  
Daily Intake ◽  
Negative Relationship ◽  
Population Based ◽  
Cardiometabolic Risk Factors ◽  
Anthropometric Measures ◽  
Cross Sectional

AbstractObjectivesDetermine the intake and percentage of adequacy of macronutrients and their association with cardiovascular risk factors in a sample of Colombian schoolchildren.MethodsCross-sectional study nested in a prospective population-based cohort in schoolchildren between 6 and 10 years of age; cardiovascular risk markers and anthropometric measures were measured. Macronutrient intake was established through a food consumption frequency questionnaire (FFQ). The percentage of adequacy was evaluated by comparison with the dietary reference intakes (DRI) and the recommendations for energy and nutrient intake (RIEN) for the Colombian population. Linear regression analysis was performed to assess the association between daily macronutrient/energy intake and cardiometabolic risk factors.ResultsA total of 1,282 school children (51.09% boys and 48.91% girls; mean age 8.4 ± 1.4 years). The percentage of energy adequacy was 107% (Q1=87.5; Q3=127.2). The macronutrients in overadequacy were proteins and carbohydrates. The total fiber had a low adequacy around 26.0% (Q1=15.8; Q3=38.6). Fat intake was positively associated with BMI, insulin, and HOMA-IR index, while carbohydrate consumption was related to these same factors, although negatively in tight models.ConclusionsSchoolchildren in this study had an inadequate protein, carbohydrate, and fiber intake. The results suggest a significant positive and negative relationship between the consumption of both fat and carbohydrates and cardiometabolic risk factors such as BMI, insulin levels, and HOMA-IR.

scholarly journals Urban index and lifestyle risk factors for cardiovascular diseases in China: A cross-sectional study

2021 ◽  
Vol 104 (1) ◽  
pp. 003685042110037
Author(s):  
Zhichong Chen ◽  
Menghui Liu ◽  
Shaozhao Zhang ◽  
Zhenyu Xiong ◽  
Xiangbin Zhong ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Fruits And Vegetables ◽  
Cross Sectional Study ◽  
Nutrition Survey ◽  
Cross Sectional ◽  
Rapid Urbanization ◽  
Lifestyle Risk Factors

China is at a stage of rapid urbanization over the past decades, and the association of urbanization with cardiovascular disease has been confirmed by previous studies. However, few studies assessed the association of urbanization with cardiovascular risk factors, especially in Chinese population. We conducted a cross-sectional, populational-based study, using data from China Health and Nutrition Survey (CHNS) in 2009. The logistic regression was used to assess the association of urbanization measured by urban index with cardiovascular risk factors (diabetes mellitus, hypertension, dyslipidemia, obesity, smoking, physical activity and fruits and vegetables consumption), varied with sex. The current study included 18,887 participants enrolled (mean age 39.8 ± 19.8 years; 52.2% female) who live in China. In regression model, the urban index was significantly associated with the variations of cardiovascular risk factors for male, including diabetes (OR 1.34, 95% CI: 1.22–1.48), hypercholesterolemia (OR 1.15, 95% CI: 1.09–1.22), never smoking (OR 0.92, 95% CI: 0.89–0.96), higher fruits and vegetables consumptions (OR 0.93, 95% CI: 0.87–0.99), higher body mass index (BMI) (OR 1.16, 95% CI: 1.10–1.22), and higher physical activity (OR 0.69, 95% CI: 0.66–0.73). Compared with the male, the associations of urban index with cardiovascular risk factors for female were similar, but not for BMI (OR 1.00, 95% CI: 0.96–1.05). The present finding emphasizes the changes of cardiovascular risk factors associated with urbanization in China, and indicated that close attention should be paid to the risk of hypercholesterolemia, diabetes and men’s obesity in the process of urbanization.

scholarly journals Assessment of cardiovascular risk factors prior to NHS Health Checks in an urban setting: cross-sectional study

2012 ◽  
Vol 3 (3) ◽  
pp. 1-11 ◽  
Author(s):  
Macide Artac ◽  
Andrew R H Dalton ◽  
Azeem Majeed ◽  
Kit Huckvale ◽  
Josip Car ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Cross Sectional Study ◽  
Urban Setting ◽  
Sectional Study ◽  
Cross Sectional ◽  
Health Checks ◽  
Nhs Health Checks

Association between dietary inflammatory index and cardiometabolic risk factors among Brazilian adolescents: results from a national cross-sectional study

2021 ◽  
pp. 1-24
Author(s):  
Pâmela Ferreira Todendi ◽  
Rafaela Salla ◽  
Nitin Shivappa ◽  
James R. Hebert ◽  
Julianna Ritter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiometabolic Risk ◽  
Positive Association ◽  
Dietary Factors ◽  
Cardiometabolic Risk Factors ◽  
Model Assessment ◽  
Dietary Inflammatory Index ◽  
Cardiovascular Risks ◽  
Cross Sectional ◽  
Inflammatory Index

Abstract Dietary factors play a role in modulating chronic inflammation and in the development of cardiovascular disease. We aimed to investigate the association between the dietary inflammatory index (DII) and cardiometabolic risk factors among adolescents.A total of 31,684 Brazilian adolescents (12–17 years), from the Study of Cardiovascular Risks in Adolescents (ERICA) were included. Dietary intake was assessed using a 24-hour dietary recall. The E-DII (energy-adjusted)score was calculated based on data for 25available nutrients. The anthropometric profile, blood pressure, lipid profile, glucose, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), and glycated hemoglobin were measured. Poisson regression models were used to examine the associations between sex-specific quartiles of the E-DII and cardiometabolic risk factors. In the energy-adjusted models, when comparing a high pro-inflammatory diet (quartile 4) withananti-inflammatory diet (quartile 1), there was a positive association with high HOMA-IR among boys(prevalence ratios (PR)Q4=1.37, 95%CI: 1.04–1.79); and with high fasting glucose (PRQ4 = 1.96, 95%CI: 1.02–3.78), high triglycerides (PRQ4 = 1.92, 95%CI: 1.06–3.46),low HDL-c (PRQ4 = 1.16, 95%CI: 1.02–1.32) and high LDL-c (PRQ4 = 1.93, 95%CI: 1.12–3.33) among girls. Additionally, a moderately pro-inflammatory diet was positively associated with high HOMA-IR (PRQ2 = 1.14, 95%CI: 1.02–1.29) among girls, and high total cholesterol (PRQ3 = 1.56, 95%CI: 1.20–2.01) among boys.In conclusion, this study provides new evidence on the association between inflammatory diets with cardiometabolic risk factors among adolescents.

Sign in / Sign up

Export Citation Format

Share Document