scholarly journals Prediction of Post-operative Visual Deterioration Using Visual-Evoked Potential Latency in Extended Endoscopic Endonasal Resection of Craniopharyngiomas

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiaorong Tao ◽  
Xiaocui Yang ◽  
Xing Fan ◽  
Hao You ◽  
Yanwen Jin ◽  
...  
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Operating Characteristic ◽  
Characteristic Curve ◽  
Threshold Value ◽  
Endoscopic Endonasal ◽  
P100 Latency ◽  
Visual Deterioration ◽  
Vep Latency ◽  
Visual Evoked

Background: The current study aimed to investigate the predictive value of visual-evoked potential (VEP) latency for post-operative visual deterioration in patients undergoing craniopharyngioma resection via extended endoscopic endonasal approach (EEEA).Methods: Data from 90 patients who underwent craniopharyngioma resection via EEEA with intraoperative VEP monitoring were retrospectively reviewed. P100 latency was compared between patients with and without post-operative visual deterioration, and the threshold value of P100 latency for predicting post-operative visual deterioration was calculated by the receiver operating characteristic curve analysis. In addition, other potential prognostic factors regarding post-operative visual outcomes were also analyzed by multivariate analysis.Results: Patients with post-operative visual deterioration showed a significantly longer VEP latency than those without (p < 0.001). An extension over 8.61% in VEP latency was identified as a predictor of post-operative visual deterioration (p < 0.001). By contrast, longer preoperative visual impairment duration and larger tumor volume were not significant predictors for post-operative visual deterioration.Conclusions: The current study revealed that intraoperative VEP monitoring in EEEA is effective for predicting post-operative visual deterioration, and an extension over 8.61% in VEP latency can be used as a critical cut-off value to predict post-operative visual deterioration.

Delayed Maturation of P2 Flash Visual Evoked Potential (VEP) Latency in Newborns of Gestational Diabetic Mothers

2021 ◽  
pp. 105503
Author(s):  
Lauren C. Shuffrey ◽  
Cynthia Rodriguez ◽  
Daianna J. Rodriguez ◽  
Hana Mahallati ◽  
Minna Jayaswal ◽  
...  
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Flash Visual Evoked Potential ◽  
Delayed Maturation ◽  
Vep Latency ◽  
Diabetic Mothers ◽  
Visual Evoked

Comparison Between Conventional Flash and Off-Response Intraoperative Visual Evoked Potential Monitoring for Endoscopic Endonasal Surgery

2021 ◽  
Author(s):  
Ridzky Firmansyah Hardian ◽  
Toshihiro Ogiwara ◽  
Atsushi Sato ◽  
Yu Fujii ◽  
Yota Suzuki ◽  
...  
Keyword(s):  
Visual Function ◽  
Predictive Value ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Light Stimulus ◽  
Warning Signal ◽  
Endoscopic Endonasal ◽  
Evoked Potential Monitoring ◽  
Flash Stimulation ◽  
Visual Evoked

Abstract BACKGROUND Intraoperative flash stimulation visual evoked potential (VEP) monitoring has been used for endoscopic endonasal approach (EEA). Recently, off-response VEP, which is recorded when the light stimulus is turned off, was introduced to monitor visual function intraoperatively. OBJECTIVE To evaluate off-response VEP monitoring in comparison with the conventional flash stimulation VEP monitoring for EEA. METHODS From March 2015 to March 2020, 70 EEA surgeries with intraoperative VEP monitoring (140 eyes) were performed. Light stimuli were delivered by a pair of goggle electrodes. Recording electrodes were placed on the scalp over the occipital region. The warning signal was prompted by a reduction of the peak-to-peak amplitude of the VEP by more than 50% compared to the initial amplitude. Visual function was assessed pre- and postoperatively. Results of flash and off-response VEP monitoring were compared. RESULTS VEP was recorded in 134 eyes. Warning signal occurred in 23 eyes (transient in 17 eyes and permanent in 6 eyes). Two eyes showed permanent VEP attenuation for flash VEP monitoring, in which one patient had postoperative visual function deterioration. Four eyes showed permanent VEP attenuation for off-response VEP monitoring, where 2 patients had postoperative visual function deterioration. Sensitivity, specificity, positive predictive value, and negative predictive value were 100%, 98.9%, 50%, and 100%, respectively, for flash stimulation VEP, and 100%, 97.8%, 50%, and 100%, respectively, for off-response VEP. CONCLUSION VEP monitoring was useful to monitor visual function in EEA surgery. Off-response VEP monitoring was not inferior to conventional flash stimulation VEP monitoring.

scholarly journals Pattern Visual Evoked Potential Changes in Diabetic Patients without Retinopathy

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ozgur Balta ◽  
Gulten Sungur ◽  
Mehmet Yakin ◽  
Nurten Unlu ◽  
Oyku Bezen Balta ◽  
...  
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Diabetes Duration ◽  
Diabetic Patients ◽  
Check Size ◽  
P100 Latency ◽  
Pattern Visual Evoked Potential ◽  
Significant Difference ◽  
Hba1c Levels ◽  
Visual Evoked

Purpose.To assess the different check sizes of pattern visual evoked potential (PVEP) in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.Methods.Fifty-eight eligible patients with type 2 diabetes mellitus and 26 age- and sex-matched healthy controls were included in the study. Only the right eye of each patient was analyzed. All of the patients underwent a comprehensive ophthalmic examination, and the PVEPs were recorded.Results.There was a statistically significant difference in P100 latency in 1-degree check size and in N135 latency in 2-degree check size between controls and patient groups which have different HbA1c levels. There were statistically significant, positive, and weak correlations with diabetes duration and P100 latency in 7-minute and 15-minute check sizes and N135 latency in 15-minute check size.Conclusions.It was showed that there were prolongations in P100 latency only in 1-degree check size and in N135 only in 2-degree check size in diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and P100 and N135 latencies in different check sizes.

scholarly journals PERAN VISUAL EVOKED POTENTIAL PADA PASIEN DIABETES MELITUS TIPE-2 DENGAN DAN TANPA RETINOPATI DIABETIK

2018 ◽  
Vol 35 (3) ◽  
Author(s):  
Bill Jones Tanawal ◽  
Melke Joanne Tumboimbela ◽  
Corry Novita Mahama
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
P100 Latency ◽  
Diabetes Melitus ◽  
Visual Evoked

ROLE OF VISUAL EVOKED POTENTIAL IN TYPE-2 DIABETES MELLITUS WITH AND WITHOUT DIABETIC RETINOPATHYABSTRACTIntroduction: Diabetic retinopathy (DR) is a common complication of type-2 diabetes mellitus (T2DM). Minimal functional change of neural layers of the retina occurs before structural changes, thus undetected by funduscopy. This damage could be identified earlier by P100 latency changes in visual evoked potential (VEP).Aims: To find the characteristic  of P100 in T2DM with and without DR, its correlation  with the duration of thedisease and the level of fasting blood glucose (FBG).Methods: A cross sectional analysis study was conducted in Prof. dr. R.D. Kandou Hospital, Manado, from November2017-January 2018. T2DM patients aged 18-60 with visual acuity  >6/60, without neuro-ophtalmological disorders and other metabolic diseases. P100 latency was measured using VEP with reversed checkerboard stimulation.Results: There were 56 subjects with T2DM, mostly were females (57,1%) and age mean was 54,86±5,65 years. Delayed P100 latency occurred in 85,7% subjects. Diabetic retinopathy subjects showed delayed P100 latency on right (92,31%) and left (88%) eyes while T2DM subjects without retinopathy showed delayed P100 latency on both eyes 70%. There were strong and significant positive correlation between the duration of T2DM and P100 latency on the right and left eyes. There was no significant correlation between fasting blood glucose (FBG) level and P100 latency.Discussions: Delayed P100 latency occurs in T2DM patients with and without retinopathy. The duration of T2DMcorrelates with the delay of P100 latency but not with the level of FBG.Keywords: Diabetic retinopathy, P100, type-2 diabetes mellitus, visual evoked potential ABSTRAKPendahuluan: Retinopati diabetik adalah suatu komplikasi yang umum terjadi pada diabetes melitus tipe-2 (DMT2). Sebelum terjadinya perubahan struktural, lapisan neuron retina pasien DMT2 sudah mengalami perubahan fungsional minimal yang tidak terdeteksi dengan funduskopi. Hal ini dapat diidentifikasi lebih dini berdasarkan gambaran latensi gelombang P100 pada pemeriksaan visual evoked potential (VEP).Tujuan: Untuk mengetahui karakteristik nilai gelombang P100 pada pasien DMT2 dengan dan tanpa retinopati diabetik, serta hubungannya dengan lama penyakit dan kadar glukosa darah puasa (GDP).Metode: Penelitian analitik dengan desain potong lintang terhadap pasien DMT2 yang dirawat di RSUP Prof. dr. R.D. Kandou, Manado periode November 2017-Januari 2018. Subjek berusia 18-60 tahun dengan visus >6/60 tanpa adanya kelainan neuro-oftamologi dan penyakit metabolik lain. Dilakukan perekaman VEP menggunakan stimulasi reversed checkerboard dilanjutkan pengukuran latensi gelombang P100.Hasil: Didapatkan 56 subjek, paling banyak perempuan (57,1%) dan rerata usia 54,86±5,65 tahun. Latensi P100 memanjang pada 85,7% subjek. Pada subjek dengan retinopati ditemukan mayoritas mengalami pemanjangan latensi pada mata kanan (92,31%) dan mata kiri (88%), sedangkan pada subjek tanpa retinopati ditemukan pemanjangan latensi kedua mata adalah 70%. Terdapat hubungan bermakna dengan korelasi positif kuat antara lamanya DMT2 dan latensi P100 kanan dan kiri. Tidak terdapat hubungan yang bermakna antara kadar GDP dan latensi P100.Diskusi: Pemanjangan latensi P100 terjadi pada subjek DMT2 dengan dan tanpa retinopati. Lamanya DMT2 berhubungan dengan pemanjangan latensi P100, tetapi kadar GDP tidak berhubungan dengan pemanjangan latensi P100.Kata kunci: Diabetes melitus tipe-2, P100, retinopati diabetik, visual evoked potential

scholarly journals Evaluation of Filtering Techniques applied to simulated Electroencephalogram signals for Visual Evoked Potential Detection

Nova Scientia ◽  
2020 ◽  
Vol 12 (25) ◽  
Author(s):  
Jesús Alejandro Montalvo-Aguilar ◽  
Ivonne Bazán ◽  
Alfredo Ramírez-García
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Extraction Methods ◽  
Denoising Method ◽  
Rectangular Window ◽  
Advantages And Disadvantages ◽  
Average Latency ◽  
Vep Latency ◽  
The Impact ◽  
Visual Evoked

Introduction: In this paper, it is presented an assessment of different windowing techniques and denoising methods applied to detect the Visual Evoked Potential (VEP) contained into the electroencephalographic (EEG) signals. The objective is to analyze advantages and disadvantages of each technique performance to identify correctly the VEP waveform and to quantify the latency which is a parameter commonly used as an indicator of ocular diseases.                       Method: Assessment of techniques was performed considering rigorous controlled conditions on the signal set, to assure that obtained results were linked just to the technique performances and avoid any undesirable effect due to the natural interference of acquisition of signals. For this reason, a simulated signals set was created based on a typical VEP waveform commonly registered around 100ms after an external stimulus was applied in the routine clinical study. Additionally, two evaluation stages were considered: fixed latency parameters stage and random latency parameters stage.Results: The best results without filter was with rectangular window and the use of elliptic filter can help to extract the VEP with a rectangular window too. For wavelet denoising the best result is Biorthogonal 2.6 wavelet with a Hamming window.                       Discussion or Conclusion: Five parameters were proposed to assessment the VEP extraction performed: signal noise ratio (SNR) mean square error (MSE), average latency (AL), latency standard deviation (LSD) and latency correlation variance (LCV) as representative factors to be considered on evaluations of VEP extraction methods. SNR and MSE were focused to assess the level of noise that remain in signal after windowing & denoising method was applied. In the other hand AL, LSD and LCV were oriented to evaluate the impact of the method on the VEP latency estimation.

scholarly journals Evaluation of Visual Evoked Potential in Psoriasis Vulgaris Patients in a Tertiary Care Centre

2021 ◽  
Vol 8 (6) ◽  
pp. 148-154
Author(s):  
T. N. Vijayalakshmi ◽  
K. Vishnu Priya ◽  
D. Celine
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Psoriasis Vulgaris ◽  
Tertiary Care ◽  
Sensory Nerves ◽  
Ophthalmological Examination ◽  
P100 Latency ◽  
Increased Risk ◽  
Visual Evoked

Psoriasis is an immunologically mediated, inflammatory disease with increased risk of painful and destructive arthritis, cardiovascular morbidity and psychosocial challenges. Psoriasis vulgaris is the most common form of psoriasis, seen in approximately 90% of patients. Besides skin, other regions widely involved are bone, cardiovascular system and eye. Psoriatic eye manifestations involve many of the structures of eye; from eyelid till optic nerve. Recording of Visual evoked potential helps in studying the integrity of optic nerve and its abnormality signifies demyelination. The concept Brain skin axis proposed in literature shows involvement of nervous system with immune mediated inflammatory pathway in Psoriasis. During intense inflammatory course, highly dense sensory nerves in plaques trigger the release of neuropeptides, targeting keratinocytes and further nerve damage. With this background, the present study was aimed to assess Optic pathway integrity by Visual Evoked Potential in patients of Psoriasis vulgaris. Materials and Methods: A Case control study was done with Institutional Ethics Committee approval and written informed consent on 100 plaque type psoriatic cases and 50 apparently healthy subjects as controls. Cases were divided into 2 groups based on their disease duration as I – new cases (1 to 5 years), II – old cases (6 to 10 years). Psoriatic patients treated with UVB and Methotrexate and with relapse of both gender of 15 to 35 years were included in the study. Patients with Diabetes Mellitus, Hypertension, any other chronic illness and autoimmune disease, severe forms of psoriasis, patients on oral steroids, and with H /O ocular diseases, eye surgery and neurological illness were excluded from the study. The mean Psoriasis Area Severity Index (PASI) was 16.09 ± 11.11. According to PASI score, the cases were categorised as <10 – mild; >11-20 – moderate; and>21 – severe. Clinical and ophthalmological examination was done for study participants. After proper instructions to patients for VEP procedure, VEP was recorded using Physiopac –NEURO PERFECT EMG 2000 SYSTEM. P100 latency of controls and cases was taken for analysis and analysed using SPSS 21.0 version. Results: There was increase in P100 latency of cases when compared to controls. P100 latency progressively increases as the severity of disease increases. Conclusion: Increased latency of P100 is a sign for demyelination. As this is seen in the present study, in psoriatic patients, there is a probability of optic nerve involvement during active state of disease. Keywords: Psoriasis, VEP, P100, PASI.

Extended endoscopic endonasal resection of craniopharyngioma using intraoperative visual evoked potential monitoring: technical note

2019 ◽  
Vol 161 (11) ◽  
pp. 2277-2284
Author(s):  
Takaaki Miyagishima ◽  
Masahiko Tosaka ◽  
Rei Yamaguchi ◽  
Tomohito Nagaki ◽  
Nobukazu Ishii ◽  
...  
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Technical Note ◽  
Endoscopic Endonasal ◽  
Evoked Potential Monitoring ◽  
Visual Evoked ◽  
Potential Monitoring

scholarly journals Applications of the isolated-check visual evoked potential in primary open angle glaucoma with or without high myopia

2021 ◽  
Vol 14 (5) ◽  
pp. 704-713
Author(s):  
Xia Wang ◽  
◽  
Ya-Hui Wei ◽  
Yuan Fang ◽  
Tian Tian ◽  
...  
Keyword(s):  
High Myopia ◽  
Diagnostic Performance ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Signal To Noise Ratio ◽  
Characteristic Curve ◽  
Open Angle ◽  
Visual Evoked

AIM: To explore the diagnostic performance of isolated-check visual evoked potential (icVEP) for primary open angle glaucoma (POAG) in both highly myopic and non-highly myopic populations and compare it with those of optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) parameters. METHODS: A total of 126 participants were recruited, including 31 highly myopic participants with POAG (HM-POAG), 36 non-highly myopic participants with POAG (NHM-POAG), 25 highly myopic participants without POAG (HM) and 34 controls without high myopia (Normal). All the participants underwent a complete ophthalmic examination. The signal-to-noise ratio (SNR) was used to assess the icVEP. Both qualitative and quantitative diagnostic performances of OCT, HRT and the icVEP were analyzed and compared. RESULTS: Based on the criterion of SNR≤1, the diagnostic performance of the icVEP in highly myopic subjects [area under the receiver operating characteristic curve (AUC)=0.862] was better than that in non-highly myopic subjects (AUC=0.789), and the SNR had fairly good specificity. In distinguishing the HM-POAG and HM groups, the AUC of the SNR was not different from those of the OCT and HRT parameters (P&#x003E;0.05) in either the qualitative or quantitative comparison. In the qualitative analysis, the icVEP showed good consistency with damage to the central 10° of the visual field (kappa=0.695-0.747, P&#x003C;0.001). CONCLUSION: The icVEP has the potential to discriminate individuals with and without POAG, especially in populations with high myopia.

Sign in / Sign up

Export Citation Format

Share Document