scholarly journals Risk Factors and Neuropsychological Assessments of Subjective Cognitive Decline (plus) in Chinese Memory Clinic

2019 ◽  
Vol 13 ◽  
Author(s):  
Lixiao Hao ◽  
Yue Xing ◽  
Xuanyu Li ◽  
Bin Mu ◽  
Weina Zhao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Subjective Cognitive Decline ◽  
Memory Clinic ◽  
Neuropsychological Assessments

Analyses of Visuospatial and Visuoperceptual Errors as Predictors of Dementia in Parkinson’s Disease Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

2020 ◽  
pp. 1-11
Author(s):  
Iván Galtier ◽  
Antonieta Nieto ◽  
María Mata ◽  
Jesús N. Lorenzo ◽  
José Barroso
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Poor Performance ◽  
Subjective Cognitive Decline ◽  
Independent Risk Factors

ABSTRACT Objective: Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) in Parkinson’s disease (PD) are considered as the risk factors for dementia (PDD). Posterior cortically based functions, such as visuospatial and visuoperceptual (VS-VP) processing, have been described as predictors of PDD. However, no investigations have focused on the qualitative analysis of the Judgment of Line Orientation Test (JLOT) and the Facial Recognition Test (FRT) in PD-SCD and PD-MCI. The aim of this work was to study the VS-VP errors in JLOT and FRT. Moreover, these variables are considered as predictors of PDD. Method: Forty-two PD patients and 19 controls were evaluated with a neuropsychological protocol. Patients were classified as PD-SCD and PD-MCI. Analyses of errors were conducted following the procedure described by Ska, Poissant, and Joanette (1990). Follow-up assessment was conducted to a mean of 7.5 years after the baseline. Results: PD-MCI patients showed a poor performance in JLOT and FRT total score and made a greater proportion of severe intraquadrant (QO2) and interquadrant errors (IQO). PD-SCD showed a poor performance in FRT and made mild errors in JLOT. PD-MCI and QO2/IQO errors were independent risk factors for PDD during the follow-up. Moreover, the combination of both PD-MCI diagnosis and QO2/IQO errors was associated with a greater risk. Conclusions: PD-MCI patients presented a greater alteration in VS-VP processing observable by the presence of severe misjudgments. PD-SCD patients also showed mild difficulties in VS-SP functions. Finally, QO2/IQO errors in PD-MCI are a useful predictor of PDD, more than PD-MCI diagnosis alone.

Differences in quantitative methods for measuring subjective cognitive decline – results from a prospective memory clinic study

2016 ◽  
Vol 28 (9) ◽  
pp. 1513-1520 ◽  
Author(s):  
Asmus Vogel ◽  
Lise Cronberg Salem ◽  
Birgitte Bo Andersen ◽  
Gunhild Waldemar
Keyword(s):  
Depressive Symptoms ◽  
Cognitive Decline ◽  
Quantitative Methods ◽  
Cognitive Status ◽  
Cognitive Test ◽  
Subjective Cognitive Decline ◽  
Linear Regression Models ◽  
Memory Clinic ◽  
Subjective Memory ◽  
Wide Range

ABSTRACTBackground:Cognitive complaints occur frequently in elderly people and may be a risk factor for dementia and cognitive decline. Results from studies on subjective cognitive decline are difficult to compare due to variability in assessment methods, and little is known about how different methods influence reports of cognitive decline.Methods:The Subjective Memory Complaints Scale (SMC) and The Memory Complaint Questionnaire (MAC-Q) were applied in 121 mixed memory clinic patients with mild cognitive symptoms (mean MMSE = 26.8, SD 2.7). The scales were applied independently and raters were blinded to results from the other scale. Scales were not used for diagnostic classification. Cognitive performances and depressive symptoms were also rated. We studied the association between the two measures and investigated the scales’ relation to depressive symptoms, age, and cognitive status.Results:SMC and MAC-Q were significantly associated (r = 0.44, N = 121, p = 0.015) and both scales had a wide range of scores. In this mixed cohort of patients, younger age was associated with higher SMC scores. There were no significant correlations between cognitive test performances and scales measuring subjective decline. Depression scores were significantly correlated to both scales measuring subjective decline. Linear regression models showed that age did not have a significant contribution to the variance in subjective memory beyond that of depressive symptoms.Conclusions:Measures for subjective cognitive decline are not interchangeable when used in memory clinics and the application of different scales in previous studies is an important factor as to why studies show variability in the association between subjective cognitive decline and background data and/or clinical results. Careful consideration should be taken as to which questions are relevant and have validity when operationalizing subjective cognitive decline.

P4-153: Subjective Cognitive Decline and Progression to Dementia Due to AD and Non-AD in Memory Clinic and Community-Based Cohorts

2016 ◽  
Vol 12 ◽  
pp. P1073-P1073
Author(s):  
Rosalinde E.R. Slot ◽  
Sietske A.M. Sikkes ◽  
Sander C.J. Verfaillie ◽  
Steffen Wolfsgruber ◽  
Henry Brodaty ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Subjective Cognitive Decline ◽  
Memory Clinic ◽  
Community Based

scholarly journals Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: Differential affective and imaging correlates

2016 ◽  
Vol 13 (5) ◽  
pp. 550-560 ◽  
Author(s):  
Audrey Perrotin ◽  
Renaud La Joie ◽  
Vincent de La Sayette ◽  
Louisa Barré ◽  
Florence Mézenge ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Subjective Cognitive Decline ◽  
Memory Clinic ◽  
Cognitively Normal ◽  
Community Or

scholarly journals SUBJECTIVE COGNITIVE DECLINE IN THE BRAZILIAN POPULATION: PRELIMINARY RESULTS OF AN ONLINE STUDY

2021 ◽  
Author(s):  
Mariana Almeida ◽  
Carina Spedo ◽  
Ari Pedro Balieiro Júnior ◽  
Paulo Caramelli ◽  
Sonia Brucki ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Cognitive Functions ◽  
Skin Color ◽  
Cross Sectional Study ◽  
Brazilian Population ◽  
Subjective Cognitive Decline ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Online Study ◽  
Neuropsychological Assessments

Background: We observe Subjective Cognitive Decline (SCD) when patients perceive a decline in their cognitive functions, but this decline is not detected in neuropsychological assessments. Few studies have investigated the prevalence of SCD in the Brazilian population. Objective: Analyze the profile of 50+ years Brazilian people regarding SCD through a self-administered online questionnaire Methods: Cross-sectional study, in the online modality. The recruitment of participants took place through email, Facebook, and WhatsApp. Results: We received 1440 responses, mainly from the country’s Southeast region (80.0%). Most of the respondents were female (67.0%), with a mean age of 58.7 (SD=8.5) years, heterosexual (97.3%), skin color referred to as white (84.5%), married (67.6%), post-graduated (51.0%) and working, but not retired (45.5%). About 55.0% reported that their memory has worsened over the past five years and 50.0% of those informed that the worsening of memory worries them. For 38.0% of the respondents, their memory is adequate. Regarding cognitive functions in the last five years, 41.0% claim that they have had problems with attention or concentration, 46.0% that their reasoning has slowed down, and 55% that they have had issues with language. Conclusion: An expressive proportion of the analyzed sample perceived a decline in their cognition at some level.

scholarly journals Dietary Patterns Are Related to Clinical Characteristics in Memory Clinic Patients with Subjective Cognitive Decline: The SCIENCe Project

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1057 ◽  
Author(s):  
Linda M. P. Wesselman ◽  
Astrid S. Doorduijn ◽  
Francisca A. de Leeuw ◽  
Sander C. J. Verfaillie ◽  
Mardou van Leeuwenstijn-Koopman ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Cognitive Decline ◽  
Dietary Patterns ◽  
Clinical Characteristics ◽  
Dietary Quality ◽  
Subjective Cognitive Decline ◽  
Memory Clinic ◽  
Science Project ◽  
Low Salt ◽  
Low Alcohol

As nutrition is one of the modifiable risk factors for cognitive decline, we studied the relationship between dietary quality and clinical characteristics in cognitively normal individuals with subjective cognitive decline (SCD). We included 165 SCD subjects (age: 64 ± 8 years; 45% female) from the SCIENCe project, a prospective memory clinic based cohort study on SCD. The Dutch Healthy Diet Food Frequency Questionnaire (DHD-FFQ) was used to assess adherence to Dutch guidelines on vegetable, fruit, fibers, fish, saturated fat, trans fatty acids, salt and alcohol intake (item score 0–10, higher score indicating better adherence). We measured global cognition (Mini Mental State Examination), cognitive complaints (Cognitive Change Index self-report; CCI) and depressive symptoms (Center for Epidemiologic Studies Depression Scale; CES-D). Using principal component analysis, we identified dietary components and investigated their relation to clinical characteristics using linear regression models adjusted for age, sex and education. We identified three dietary patterns: (i) “low-Fat-low-Salt”, (ii) “high-Veggy”, and (iii) “low-Alcohol-low-Fish”. Individuals with lower adherence on “low-Fat-low-Salt” had more depressive symptoms (β −0.18 (−2.27–−0.16)). Higher adherence to “high-Veggy” was associated with higher MMSE scores (β 0.30 (0.21–0.64)). No associations were found with the low-Alcohol-low-Fish component. We showed that in SCD subjects, dietary quality was related to clinically relevant outcomes. These findings could be useful to identify individuals that might benefit most from nutritional prevention strategies to optimize brain health.

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