scholarly journals Dietary Intake of Calcium and Magnesium in Relation to Severe Headache or Migraine

2021 ◽  
Vol 8 ◽  
Author(s):  
Shu-Han Meng ◽  
Ming-Xue Wang ◽  
Li-Xin Kang ◽  
Jin-Ming Fu ◽  
Hai-Bo Zhou ◽  
...  

Background: Migraine is a common neurological disorder and is affected by nutrients. Calcium and magnesium are essential minerals that play an important role in nerve function. So we investigated the association between dietary calcium and magnesium and migraine.Methods: We extracted 10,798 adults from the National Health and Nutrition Examination Surveys (NHANES) of America in 1999 to 2004. We classified patients who reported having severe headache or migraine as having possible migraine. Multivariable logistic regression and restricted cubic spline regression were conducted to determine the association between dietary calcium and magnesium and migraine.Results: We found that the adjusted ORs of the association between dietary calcium and magnesium and migraine for comparing the highest quintile intake with the lowest quintile intake were 0.77 (95% CI: 0.63–0.93, P = 0.008) and 0.69 (95% CI: 0.55–0.86, P = 0.001), respectively. For women, the adjusted ORs of dietary calcium and magnesium were 0.72 (95% CI: 0.56–0.93, P = 0.009) and 0.62 (95% CI: 0.47–0.83, P = 0.001), respectively. For men, the adjusted OR was 0.71 (95% CI: 0.52–0.97, P = 0.028) comparing the highest and the lowest quintile of calcium intake, but there was no statistically significant association between dietary magnesium intake and migraine. Joint analyses showed that the OR in the high-calcium and high-magnesium group was 0.74 (95% CI: 0.60–0.92, P = 0.006) compared with the low-calcium and low-magnesium group in women.Conclusions: High dietary intake of calcium and magnesium, independently or in combination, were inversely associated with migraine in women. For men, high dietary calcium was negatively related to migraine, but magnesium was not associated with migraine.

2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Gábor Speer ◽  
Pál Szamosujvári ◽  
Péter Dombai ◽  
Katalin Csóré ◽  
Kinga Mikófalvi ◽  
...  

Purpose. Adequate calcium intake is the basis of osteoporosis therapy—when this proves insufficient, even specific antiosteoporotic agents cannot exert their actions properly.Methods. Our representative survey analyzed the dietary intake and supplementation of calcium in 8033 Hungarian female and male (mean age: 68 years) (68.01 (CI95: 67.81–68.21)) patients with osteoporosis.Results. Mean intake from dietary sources was665±7.9 mg (68.01 (CI95: 67.81–68.21)) daily. A significant positive relationship could be detected between total dietary calcium intake and lumbar spine BMD (P=0.045), whereas such correlation could not be demonstrated with femoralT-score. Milk consumption positively correlated with femur (P=0.041), but not with lumbar BMD. The ingestion of one liter of milk daily increased theT-score by 0.133. Average intake from supplementation was558±6.2 mg (68.01 (CI95: 67.81–68.21)) daily. The cumulative dose of calcium—from both dietary intake and supplementation—was significantly associated with lumbar (r=0.024,P=0.049), but not with femur BMD (r=0.021,P=0.107). The currently recommended 1000–1500 mg total daily calcium intake was achieved in 34.5% of patients only. It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects.Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients.


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 15-15
Author(s):  
Liam Fouhy ◽  
Kelsey Mangano ◽  
Xiyuan Zhang ◽  
Brittany Adelman ◽  
Katherine Tucker ◽  
...  

Abstract Objectives Dietary calcium and magnesium have been shown to be beneficial for bone health primarily in non-Hispanic white populations.  There are no studies of calcium and magnesium intake among Hispanics of Caribbean origin. A calcium to magnesium ratio (Ca: Mg) may be important due to their competitive nature during absorption. This study examined associations between dietary calcium and magnesium and osteoporosis, accounting for calcium to magnesium ratio among Puerto Rican adults Methods Data from the Boston Puerto Rican Osteoporosis Study were used. Puerto Ricans aged 47–79 y with complete data on bone and diet were included (n = 955). Bone measures were assessed using dual-energy X-ray absorptiometry. A food frequency questionnaire adapted for this population was used. Dietary calcium and magnesium were energy adjusted using the residual method. Tertiles of Ca : Mg were calculate. Multivariable logistic regressions modeled associations between calcium, magnesium and tertiles of Ca : Mg. Model 1 included Ca : Mg tertiles and dietary magnesium; Model 2 Ca : Mg tertiles and dietary calcium; Model 3 Ca : Mg tertiles and dietary calcium and magnesium. All models were adjusted for age, estrogenic status (male, non-menopausal or taking estrogen, postmenopausal not taking estrogen), height, BMI, calcium (0, 0–300 mg, ≥300 mg) and magnesium (0, 0–100 mg) supplement use, serum vitamin D, alcohol use, smoking status, and bone medication use. Results Mean age was 59.9 y ± 7.6 and 71.3% were female. In model 1, the highest tertile of Ca : Mg was associated with higher likelihood (OR: 1.3; 95%CI: 0.77, 2.4) and the middle tertile with lower likelihood (OR: 0.51; 95%CI: 0.26,0.99) of osteoporosis compared with the lowest Ca: Mg tertile. Dietary magnesium was also associated with lower odds of osteoporosis (OR: 0.99; 95%CI: 0.98, 0.99). In model 2, dietary calcium (OR: 0.99, 95%CI: 0.99, 1.0) was associated with lower of odds osteoporosis, but Ca: Mg was not. In model 3, dietary calcium and magnesium and tertiles of Ca : Mg were not associated with osteoporosis. Conclusions Dietary calcium and magnesium are important nutrients for bone health in Puerto Rican older adults. The Ca : Mg ratio appears optimal within a range of 2.6–3.1 suggesting that a balance of these two nutrients is most important. Funding Sources National Institutes of Health P01 AG023394, P50 HL105185,  R01 AG027087 K01 AR067894


1961 ◽  
Vol 41 (1) ◽  
pp. 50-58 ◽  
Author(s):  
R. W. Shuel

The effect on nectar production of factorial combinations of three levels each of calcium and magnesium, comprising a ninefold variation in concentration, was studied in red clover and snapdragon. Plants were grown in sand and the essential elements supplied by daily sub-irrigation. Nectar secretion in red clover was comparatively sensitive to the availability of calcium and magnesium, the best factorial combination (intermediate calcium and high magnesium) producing almost twice as much nectar per unit of inflorescence weight as the poorest (low calcium and low magnesium). Nectar production was not correlated with vegetative growth or flower production. Inter-treatment variation was less extreme in snapdragon. In one crop the combination of high calcium and high magnesium, which supported the best growth and flower production, also gave the best nectar yield; in another crop the lowest level of calcium, sub-optimal for growth, produced the most nectar. The effects of nutrition on secretion were not related to the influence of pH, which was constant, or to the content of calcium, magnesium, nitrogen, phosphorus, or potassium in the red clover or snapdragon shoots.


Author(s):  
Rebecca B Costello ◽  
Andrea Rosanoff ◽  
Qi Dai ◽  
Leila G Saldanha ◽  
Nancy A Potischman

ABSTRACT Low magnesium intakes coupled with high calcium intakes and high calcium-to-magnesium (Ca:Mg) intake ratios have been associated with increased risk for multiple chronic conditions such as cardiovascular disease and metabolic syndrome, as well as some cancers (colorectal, prostate, esophageal), and total mortality. A high dietary Ca:Mg ratio (>2.60) may affect body magnesium status while, on the other hand, high intakes of magnesium could adversely impact individuals with an exceedingly low dietary Ca:Mg ratio (<1.70). Thus, a Ca:Mg ratio range of 1.70–2.60 (weight to weight) has been proposed as an optimum range. Data from NHANES surveys have shown the mean Ca:Mg intake ratio from foods alone for US adults has been >3.00 since 2000. One-third of Americans consume a magnesium supplement with a mean dose of 146 mg/d, and 35% of Americans consume a calcium supplement with a mean dose of 479 mg/d. Our review of Ca:Mg ratios in dietary supplements sold in the United States and listed in NIH's Dietary Supplement Label Database (DSLD) found a mean ratio of 2.90 across all calcium- and magnesium-containing products, with differences by product form. The ratios ranged from a low of 0.10 in liquid products to a high of 48.5 in powder products. Thirty-one percent of products fell below, 40.5% fell within, and 28.3% fell above the ratio range of 1.70–2.60. Our findings of calculated Ca:Mg ratios from dietary supplements coupled with food-intake data suggest that, in individuals with high calcium intakes from diet and/or supplements, magnesium supplementation may be warranted to establish a more favorable dietary Ca:Mg ratio in their total diet. Additional research may provide greater insight into whether the Ca:Mg ratio is a biomarker of interest for moderating chronic disease and which population groups may derive benefit from moderating that ratio.


Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2952
Author(s):  
Yong Zhu ◽  
Neha Jain ◽  
Vipra Vanage ◽  
Norton Holschuh ◽  
Anne Hermetet Agler ◽  
...  

This study examined differences in dietary intake between ready-to-eat cereal eaters and non-eaters in adults from the United States. Participants (n = 5163) from the National Health and Nutrition Examination Survey 2015–2016 were included. One-day dietary recall was used to define ready-to-eat cereal consumption status and estimate dietary intake in eaters and non-eaters. Data from Food Patterns Equivalent Database 2015–2016 were used to compare intakes of food groups by consumption status. Diet quality was assessed by Healthy Eating Index 2015. Nineteen percent of US adults were ready-to-eat cereal eaters; they had a similar level of energy intake as non-eaters, but they had significantly higher intake of dietary fiber, and several vitamins and minerals, such as calcium, iron, magnesium, potassium, zinc, vitamin A, thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, and vitamin D. They were also more likely to meet nutrient recommendations. Compared to non-eaters, ready-to-eat cereal eaters had the same level of added sugar intake but they had significantly higher intake of whole grains, total fruits, and dairy products. The diet quality of ready-to-eat cereal eaters was significantly higher than that of non-eaters. The study supports that ready-to-eat cereal eaters have better dietary intake with a healthier dietary pattern than non-eaters in the United States.


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