scholarly journals Comparison of Persistent Symptoms After COVID-19 and Other Non-SARS-CoV-2 Infections in Children

2021 ◽  
Vol 9 ◽  
Author(s):  
Ieva Roge ◽  
Liene Smane ◽  
Anda Kivite-Urtane ◽  
Zanda Pucuka ◽  
Iveta Racko ◽  
...  

Introduction: The data on long COVID in children is scarce since children and adolescents are typically less severely affected by acute COVID-19. This study aimed to identify the long-term consequences of SARS-CoV-2 infection in children, and to compare the persistent symptom spectrum between COVID-19 and community-acquired infections of other etiologies.Methods: This was an ambidirectional cohort study conducted at the Children's Clinical University Hospital in Latvia. The study population of pediatric COVID-19 patients and children with other non-SARS-CoV-2-community-acquired infections were invited to participate between July 1, 2020, and April 30, 2021.Results: In total, 236 pediatric COVID-19 patients were enrolled in the study. Additionally, 142 comparison group patients were also enrolled. Median follow-up time from acute symptom onset was 73.5 days (IQR; 43–110 days) in the COVID-19 patient group and 69 days (IQR, 58–84 days) in the comparison group. Most pediatric COVID-19 survivors (70%, N = 152) reported at least one persistent symptom, but more than half of the patients (53%, N = 117) noted two or more long-lasting symptoms. The most commonly reported complaints among COVID-19 patients included persistent fatigue (25.2%), cognitive sequelae, such as irritability (24.3%), and mood changes (23.3%), as well as headaches (16.9%), rhinorrhea (16.1%), coughing (14.4%), and anosmia/dysgeusia (12.3%). In addition, 105 (44.5%) COVID patients had persistent symptoms after the 12-week cut-off point, with irritability (27.6%, N = 29), mood changes (26.7%, N = 28), and fatigue (19.2%, N = 20) being the most commonly reported ones. Differences in symptom spectrum among the various age groups were seen. Logistic regression analysis showed that long-term persistent symptoms as fever, fatigue, rhinorrhea, loss of taste and/or smell, headaches, cognitive sequelae, and nocturnal sweating were significantly associated with the COVID-19 experience when compared with the controls.Conclusions: We found that at the time of interview almost three-quarters of children reported at least one persistent symptom, but the majority of patients (53%) had two or more concurrent symptoms. The comparison group's inclusion in the study allowed us to identify that symptom persistence is more apparent with COVID-19 than any other non-SARS-CoV-2 infection. More research is needed to distinguish the symptoms of long COVID from pandemic-associated complaints. Each persistent symptom is important in terms of child well-being during COVID-19 recovery.

2020 ◽  
pp. ijgc-2020-002145
Author(s):  
Saira Sanjida ◽  
Andreas Obermair ◽  
Val Gebski ◽  
Nigel Armfield ◽  
Monika Janda

ObjectiveTo compare long-term quality of life in women treated for early-stage endometrial cancer with population norms, and to compare quality of life outcomes of patients who had total laparoscopic or total abdominal hysterectomy.MethodsOnce the last enrolled patient had completed 4.5 years of follow-up after surgery, participants in the Laparoscopic Approach to Cancer of the Endometrium (LACE) clinical trial were asked to complete a self-administered questionnaire. Two instruments—EuroQol 5 Dimension 3-level (EQ-5D-3L) and the Functional Assessment of Cancer Treatment-General Population (FACT-GP)—were used to determine quality of life. The mean computed EQ-5D-3L index scores for LACE participants at different age categories were compared with Australian normative scores; and the FACT-GP scores were compared between patients treated with surgical treatments.ResultsOf 760 women originally enrolled in the LACE trial, 259 (50.2%) of 516 women consented to provide long-term follow-up data at a median of 9 years (range 6—12) after surgery. On the EQ-5D-3L, long-term endometrial cancer survivors reported higher prevalence of anxiety/depression than normative levels across all age groups (55–64 years, 30% vs 14.9%; 65–74 years, 30.1% vs 15.8%; ≥75 years, 25.9% vs 10.7%). For women ≥75 years of age, the prevalence of impairment in mobility (57.6% vs 43.3%) and usual activities (58.8% vs 37.9%) was also higher than for population norms. For the FACT-GP, the physical (effect size: −0.28, p<0.028) and functional (effect size: −0.30, p<0.015) well-being sub-scale favored the total laparoscopic hysterectomy compared with total abdominal hysterectomy recipients.ConclusionCompared with population-based norms, long-term endometrial cancer survivors reported higher prevalence of anxiety/depression across all age groups, and deficits in mobility and usual activities for women aged ≥75 years. Physical and functional well-being were better among women who were treated with total laparoscopic hysterectomy than among those receiving total abdominal hysterectomy.


Organizacija ◽  
2017 ◽  
Vol 50 (1) ◽  
pp. 47-62 ◽  
Author(s):  
Maja Rožman ◽  
Sonja Treven ◽  
Vesna Čančer ◽  
Marijan Cingula

Abstract Background and Purpose: People spend a significant part of their lifespan working, but the role of age in job design and implementation of work have largely been ignored. The consequences can be evident in stress and burnout in different symptoms. Thus, age-diverse employees are faced with different symptoms of burnout and stress when carrying out their work. The main aim of this paper is to present burnout of older employees compared to younger employees in Slovenian companies. Design/Methodology/Approach: The paper is based on research including a survey between two age groups of employees, namely the younger employees that were classified in the group of under 50 years of age and the older employees that were classified in the group of above 50 years of age. Since the Kolmogorov-Smirnov and Shapiro- Wilk test showed that the data was not normally distributed, the noan-parametric Mann-Whitney U test was used to verify differences in the physical symptoms of burnout, emotional symptoms of burnout, and behavioral symptoms of burnout in the workplace between two groups. Results: The results show that there are significant differences in the great majority of the variables describing the physical symptoms of burnout, emotional symptoms of burnout, and behavioral symptoms of burnout in the workplace between younger and older employees. Conclusion: Well-being in the workplace of age-diverse employees is a key for long-term effectiveness of organizations. Managers and employers should apply appropriate measures to reduce burnout as well as to contribute to employees well-being and better workplace performance.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 385-385
Author(s):  
Kelly Shryock ◽  
Suzanne Meeks

Abstract Residence in a long-term care (LTC) facility poses numerous challenges to psychological well-being and rates of depression are high. Sense of belonging (SoB) has been linked with measures of well-being in all age groups and interventions focused on improving SoB have been successful with college-age adults. It is unclear if SoB improves in LTC residents as they adjust to living in this environment or what factors predict poor SoB in this population. As part of a larger study of care preferences in LTC residents, participants (n= 76) completed measures of SoB, well-being, religious activity, and demographic information. SoB did not vary significantly based on duration of stay, age, gender, ethnicity, marital status, number of children, education, facility, cognitive functioning, or physical health. SoB was found to be significantly and positively correlated with participation in religious activities (r= .388, N=76, p=.001), private religious practices (r= .275, N=71, p=.020), and spirituality (r= .263, N=70, p=.028). There was also a significant positive correlation between SoB and positive affect (r= .450, N=74, p&lt;.001) and SoB and life satisfaction (r= .393, N=74, p=.001). These results suggest that connections formed before admission to a LTC facility, including religious networks, are important to SoB and well-being and that individuals without or with low religious involvement may benefit most from interventions focusing on improving SoB in LTC residents.


2019 ◽  
Vol 18 (3) ◽  
pp. 81-86
Author(s):  
Vasilios Pergialiotis ◽  
Chryssoula Botsi ◽  
Ioanna Papari ◽  
Stavroula Gkritziou ◽  
Kassiani Mellou ◽  
...  

Objective:The purpose of the present article is to present preliminary data related to the gynecological history and current health status of pregnant refugees that reside in long-term refugee camps in Greece. Materials and Methods: The study was funded by the European program “PHILOS – Emergency health response to refugee crisis” of the Greek Ministry of Health, implemented by the Hellenic Center for Disease Control and Prevention (HCDCP), funded by the Asylum, Migration and Integration Fund (AMIF) of EU’s DG Migration and Home Affairs.Refugee pregnant women who resided in long-stay refugee camps of the mainland in Greece in 2017 were recruited. Results: Overall, 456 pregnant women were enrolled in the present study with a mean age of 27.5±6.9 years (median 27, range 17-48 years). 182 women (39.8%) were primigravidae. Mean gravidity was 2.4 (median 2, range 1-11). Among them 105 had a previous delivery, 75 women had 2 previous deliveries, 50 women had 3 previous deliveries and 14 had four previous deliveries. Of those, only six women had access to prenatal screening.Twenty-three women (5%) reported that had at least an artificial abortion performed (median 1, range 1-4) and 87 women (19.0%) had at least one spontaneous abortion (median 1, range 1-6).Two hundred and three women (44.5%) reported the use of a contraceptive method. Among them withdrawal (pull-out method) was the most prevalent accounting for almost half cases (36.9%), by followed by condom, intrauterine devices (IUD) and oral contraceptives. No differences were observed after checking the potential differences among the different age groups (p=.234). Conclusions: Refugee women that reside in long term refugee camps have limited access to national healthcare systems concerning their gynecological and obstetrical assessment. Future studies, should specifically target these problems to help structure specific healthcare plans that will ensure maternal and fetal well-being.


2020 ◽  
Author(s):  
Emily E Cameron ◽  
Kayla M. Joyce ◽  
Chantal P Delaquis ◽  
Kristin Reynolds ◽  
Jennifer Protudjer ◽  
...  

Background: Mental health problems are increasingly recognized as a significant and concerning secondary effect of the COVID-19 pandemic. Research on previous epidemics/pandemics suggest that families, particularly mothers, may be at increased risk, but this population has yet to be examined. The current study (1) described prevalence rates of maternal depressive and anxiety symptoms from an online convenience sample during the COVID-19 pandemic, (2) identified risk and protective factors for elevated symptoms, and (3) described current mental health service use and barriers. Methods: Participants (N = 641) were mothers of children age 0-8 years, including expectant mothers. Mothers completed an online survey assessing mental health, sociodemographic information, and COVID-19-related variables. Results: Clinically-relevant depression was indicated in 33.16%, 42.55%, and 43.37% of mothers of children age 0-18 months, 18 months to 4 years, and 5 to 8 years, respectively. Prevalence of anxiety was 36.27%, 32.62%, and 29.59% for mothers across age groups, respectively. Binary logistic regressions indicated significant associations between risk factors and depression/anxiety across child age groups. Limitations: Cross-sectional data was used to describe maternal mental health problems during COVID-19 limiting the ability to make inferences about the long-term impact of maternal depression and anxiety on family well-being. Conclusions: Maternal depression and anxiety appear to be elevated in the context of COVID-19 compared to previously reported population norms. Identified risk factors for depression and anxiety across different child age ranges can inform targeted early intervention strategies to prevent long-term impacts of the COVID-19 pandemic on family well-being and child development.


Author(s):  
Don Goldenberg

The symptoms, risk factors and typical course of mild, moderate and severe COVID-19 infections are detailed, focusing on correlations with hospitalization and death. The physical and emotional toll on healthcare workers is described, as well as the innovations and sacrifices made by physicians, nurses, and hospitals during the pandemic. Present and enduring changes in primary care and mental healthcare, including increased utilization of telemedicine, are explained. The misinformation and disinformation raging during the pandemic and their adverse effect on public health and patient recovery are uncovered. There is a focus on persistent symptoms, long after the initial COVID infection, including long-COVID syndrome. The book concludes with recommendations to best move forward, addressing public health, healthcare inequities, long-term care facilities, primary care, healthcare worker well-being, and following science and truth.


2020 ◽  
pp. 088506662094917
Author(s):  
Christine H. Meyer-Frießem ◽  
Nathalie M. Malewicz ◽  
Sabrina Rath ◽  
Melanie Ebel ◽  
Miriam Kaisler ◽  
...  

Purpose: Intensive care unit-acquired weakness (ICUAW) can manifest as muscle weakness or neuropathy-like symptoms, with diagnosis remaining a challenge. Uncertainties surround the long-term cause and sequelae. Therefore, the purpose was to assess incidence, time course and long-term influence on quality of life (QoL) of symptoms in ICU survivors Methods: After ethical approval and registration ( www.drks.de : DRKS00011593), in a single-center cohort study all patients admitted to the ICU in 2007–2017 in a German university hospital were screened. Out of 1,860 patients (≥7d ICU care including ventilation support for ≥72 h, at least 6mo-10y after ICU) 636 were deceased, 912 survivors were contacted. Results: 149 former patients (age: 63.5 ± 13.1y; males: 73%; duration in ICU: 20.8 ± 15.7d; duration of ventilation: 16.5 ± 13.7 h; time post-ICU: 4.4 ± 2.7y, 5-10y: 43%) consented to be interviewed concerning occurrence, duration, recovery and consequences of ICUAW-associated muscle weakness or neuropathy-like symptoms after ICU. In 75% at least 1 persistent or previous symmetrical symptom was reported (myopathy-like muscle weakness: 43%; neuropathy-like symptoms: 13%; both: 44%) and rated as incidence of ICUAW. However, only 18% of participants had received an ICUAW diagnosis by their physicians, although 62% had persistent symptoms up to 10y after ICU (5-10y: 46%). Only 37% of participants reported a complete recovery of symptoms, significantly associated with an initially low number of symptoms after ICU ( p < 0.0001), myopathy-like symptoms ( p = 0.024), and younger age at the time of ICU admission (55.7 ± 13.1 vs. 62.6 ± 10.6y, p < 0.001). ICUAW still impaired the QoL at the time of the interview in 74% of affected survivors, with 30% reporting severe impairment. Conclusion: ICUAW symptoms were disturbingly common in the majority of long-term survivors, indicating that symptoms persist up to 10y and frequently impair QoL. However, only a small number of patients had been diagnosed with ICUAW. Trial registry: Deutsches Register Klinischer Studien (DRKS), https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00011593 , registration number: DRKS00011593.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 552-556
Author(s):  
Ramya G ◽  
Remmiya Mary Varghese ◽  
Jeevitha M

Orthognathic surgery is a unique endeavour in facial surgery, a patient’s appearance and occlusal function can be improved significantly, which has a great impact on the patient’s sense of self and well-being. Successful outcomes in modern orthognathic surgery rely on a close collaboration between the surgeon and the orthodontist across all stages of treatment. To assess the frequency of orthognathic surgery in a university hospital setting. Data required for the study was procured by reviewing patient records and analyzed data of 86000 patients between June 2019 to March 2020. The data was sorted in excel and statistically analyzed using the IBM SPSS software analysis and the results tabulated. The frequency of orthognathic surgery in this study was found to be 22.4%. Orthognathic surgery improves the quality of life for all age groups of dentofacial deformities and hence it is imperative to educate people regarding the same.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 95-95
Author(s):  
Giorgio Di Gessa ◽  
Debora Price

Abstract People with specific health profiles and diseases (such as diabetes, lung and heart conditions) have been classified as ‘clinically vulnerable’ (CV) to Covid-19, i.e. at higher risk of severe illness and mortality from Covid-19, and were targeted for shielding. However, there is as yet little evidence on how the pandemic and shielding impacted the health and social well-being of CV older people. Using data from Wave 9 (2018/19) and the first Covid-19 sub-study (June/July 2020) of the English Longitudinal Study of Ageing, we investigated changes in health and well-being during the pandemic by clinical vulnerability. We also explored the interactions between CV and age-group (50s, 60s, 70s, 80+), and between CV and shielding. Results suggest that CV older people (~39% of the sample) were more likely to report worse health and social well-being outcomes during the pandemic compared to non-CV participants, even considering pre-pandemic levels of health and well-being. However, changes in health were not uniform across age groups, with those in their 50s and 60s more likely to report greater deterioration in mental health than those in their 70s and over 80. Moreover, older adults who were shielding and were CV reported the most substantial rises in anxiety, depression, receipt of formal care as well as decreases in well-being and physical activity. While policies focussing on shielding CV older people reduce rates of hospitalisation and death from Covid-19, policymakers should address the wider needs of this group if their long-term health and social well-being are not to be compromised.


2014 ◽  
Vol 32 (26_suppl) ◽  
pp. 23-23
Author(s):  
Donald Brooks Johnson ◽  
Brittany Lapin ◽  
Chihsiung Wang ◽  
Katharine Yao ◽  
Mark Sisco

23 Background: Despite evidence that postmastectomy breast reconstruction (PMBR) yields important quality of life benefits, older women (≥ 65 years) rarely receive it. While the perception is that PMBR may result in greater physical morbidity in older women, the additive effects of age and PMBR on physical morbidity have not been studied. This study sought to assess long-term chest and upper body morbidity in older women who receive PMBR. Methods: Women with AJCC stage 0 to III breast cancer who underwent a mastectomy ± PMBR in 2006 to 2011 were surveyed; physical well-being was assessed using the BREAST-Q. Patients were grouped into (3) cohorts: younger (< 65 years) women who underwent PMBR, older women who underwent PMBR, and older women who underwent mastectomy alone. The groups were propensity matched (1:1) to control for differences. Data were analyzed using chi-square and t-tests. Results: 74 younger PMBR, 60 older PMBR, and 88 older unreconstructed mastectomy patients returned surveys (75.3% response rate). The median time from mastectomy to survey was 4.2 years. Younger women were more likely to undergo bilateral mastectomy than older women (54.3% vs. 28.4%, p < 0.001). 63.5% of women underwent implant-only reconstruction and 36.5% underwent autologous reconstruction; there were no significant differences in reconstruction type between age groups. Neither bilateral surgery nor reconstruction type affected BREAST-Q physical well-being scores. Among older women, PMBR was associated with lower mean physical well-being scores than mastectomy alone (79.4 vs. 87.4, p = 0.017, Cohen’s d = 0.56). However, there was no difference in physical well-being scores between older and younger PMBR patients (79.4 vs. 78.5, p = 0.614). Older PMBR patients perceived recovery from surgery as difficult more often than older unreconstructed patients (46% vs. 33%, p = 0.013), but less often than younger PMBR patients (46% vs. 61%, p = 0.036). Conclusions: Older women who undergo PMBR have more long-term chest and upper body morbidity than those who do not have PMBR. However, their morbidity from PMBR and perception of recovery from surgery is comparable to that of younger women. Older women should be counseled that while PMBR is associated with more long-term chest and upper body morbidity, this outcome is independent of age.


Sign in / Sign up

Export Citation Format

Share Document