scholarly journals Acute Normobaric Hypoxia Increases Post-exercise Lipid Oxidation in Healthy Males

2017 ◽  
Vol 8 ◽  
Author(s):  
Liam P. Kelly ◽  
Fabien A. Basset
Keyword(s):  
Lipid Oxidation ◽  
Normobaric Hypoxia ◽  
Post Exercise ◽  
Healthy Males

The Basis for the Increase in Factor VIII Procoagulant Activity During Exercise

1983 ◽  
Vol 49 (01) ◽  
pp. 053-057 ◽  
Author(s):  
Robert G Kopitsky ◽  
Mary Ellen P Switzer ◽  
R Sanders Williams ◽  
Patrick A McKee
Keyword(s):  
Factor Viii ◽  
Acute Exercise ◽  
Post Exercise ◽  
Fviii Activity ◽  
Plasma Factor ◽  
The Subject ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Healthy Males ◽  
Related Increase

SummaryWe studied the effect of acute exercise on the ability of thrombin to activate plasma factor VIII (FVIII) activity in 20 healthy males. The subject showed an average exercise-related increase in FVIII activity of 54.5±8.2% over pre-exercise FVIII activity (p<0.001). When exposed to the same concentration of thrombin, post-exercise FVIII activity showed greater enhancement than pre-exercise FVIII activity: 157.1±12.8% increase in activity versus 117.3±9.9%, respectively (p<0.01). The degree of the potentiated thrombin effect in post-exercise samples relative to pre-exercise samples was linearly correlated with the degree of the exercise-related increase in FVIII activity. Taken together with our previous observations that the extent of thrombin enhancement of FVIII activity varies inversely with the mole ratio of FVIII/von Willebrand factor subunits to thrombin, these findings imply that release of FVIII does not occur during exercise, and that the exercise-related increase in FVIII activity results primarily, if not completely, from activation of already circulating but inactive FVIII.

Post-exercise accumulation of interstitial lung water is greater in hypobaric than normobaric hypoxia in adults born prematurely

2022 ◽  
Vol 297 ◽  
pp. 103828
Author(s):  
Tadej Debevec ◽  
Mathias Poussel ◽  
Damjan Osredkar ◽  
Sarah J. Willis ◽  
Claudio Sartori ◽  
...  
Keyword(s):  
Normobaric Hypoxia ◽  
Lung Water ◽  
Post Exercise

scholarly journals Taurine Supplementation Increases Post-Exercise Lipid Oxidation at Moderate Intensity in Fasted Healthy Males

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1540 ◽  
Author(s):  
Milena Barbon de Carvalho ◽  
Camila Fernanda Cunha Brandao ◽  
Priscila Giacomo Fassini ◽  
Thiago Mantello Bianco ◽  
Gabriela Batitucci ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Aerobic Exercise ◽  
Young Men ◽  
Moderate Intensity ◽  
Taurine Supplementation ◽  
Double Blind ◽  
Post Exercise ◽  
Fasted State ◽  
Single Bout ◽  
Different Doses

Based on the fact that taurine can increase lipid metabolism, the objective of the present study was to evaluate the effects of different doses of acute taurine supplementation on lipid oxidation levels in healthy young men after a single bout of fasting aerobic exercise. A double-blind, acute, and crossover study design was conducted. Seventeen men (age 24.8 ± 4.07y; BMI: 23.9 ± 2.57 kg/m²) participated in the present study. Different doses of taurine (TAU) (3 g or 6 g) or placebo were supplemented 90 min before a single bout of fasting aerobic exercise (on a treadmill at 60% of VO2 max). The subjects performed three trials, and each one was separated by seven days. Blood samples were collected at baseline and after the exercise protocol of each test to analyze plasma levels of glycerol and taurine. Lipid and carbohydrate oxidation were determined immediately after exercise for 15 min by indirect calorimetry. We observed that TAU supplementation (6 g) increased lipid oxidation (38%) and reduced the respiratory coefficient (4%) when compared to the placebo (p < 0.05). However, no differences in lipid oxidation were observed between the different doses of taurine (3 g and 6 g). For glycerol concentrations, there were no differences between trials. Six grams of TAU supplementation 90 min before a single bout of aerobic exercise in a fasted state was sufficient to increase the lipid oxidation post-exercise in healthy young men.

Acute Normobaric Hypoxia Exposure and Excess Post-Exercise Oxygen Consumption

2018 ◽  
Vol 89 (12) ◽  
pp. 1031-1035
Author(s):  
James W. Navalta ◽  
Elizabeth A. Tanner ◽  
Nathaniel G. Bodell
Keyword(s):  
Oxygen Consumption ◽  
Normobaric Hypoxia ◽  
Post Exercise ◽  
Hypoxia Exposure

scholarly journals A pilot investigation into the effects of acute normobaric hypoxia, high altitude exposure and exercise on serum angiotensin-converting enzyme, aldosterone and cortisol

2018 ◽  
Vol 19 (2) ◽  
pp. 147032031878278 ◽  
Author(s):  
Mark Cooke ◽  
Richard Cruttenden ◽  
Adrian Mellor ◽  
Andrew Lumb ◽  
Stewart Pattman ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
High Altitude ◽  
Prolonged Exposure ◽  
Normobaric Hypoxia ◽  
Converting Enzyme ◽  
Serum Angiotensin Converting Enzyme ◽  
Post Exercise ◽  
Altitude Exposure ◽  
Pilot Investigation ◽  
Ace Activity

Introduction: Aldosterone decreases at high altitude (HA) but the effect of hypoxia on angiotensin-converting enzyme (ACE), a key step in the renin-angiotensin-aldosterone system, is unclear. Methods: We investigated the effects of exercise and acute normobaric hypoxia (NH, ~11.0% FiO2) on nine participants and six controls undertaking the same exercise at sea level (SL). NH exposure lasted 5 hours with 90 minutes of submaximal treadmill walking. Blood samples for aldosterone, ACE and cortisol were taken throughout exposure and at rest during a trek to HA (5140 m) in eight separate participants. Results: There was no difference in cortisol or aldosterone between groups pre-exercise. Aldosterone rose with exercise to a greater extent at SL than in NH (post-exercise: 700 ± 325 versus 335 ± 238 pmol/L, mean ± SD, p = 0.044). Conversely, cortisol rose to a greater extent in NH (post-exercise: 734 ± 165 versus 344 ± 159 nmol/L, mean ± SD, p = 0.001). There were no differences in ACE activity. During the trek to HA, resting aldosterone and cortisol reduced with no change in ACE. Conclusions: Acute NH subdues the exercise-associated rise in aldosteroe but stimulates cortisol, whereas prolonged exposure at HA reduces both resting aldosterone and cortisol. As ACE activity was unchanged in both environments, this is not the mechanism underlying the fall in aldosterone.

scholarly journals An acute eccentric exercise increases circulating myomesin 3 fragments

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Minjung Lee ◽  
Jaehoon Shin ◽  
Tatsuya Kato ◽  
Kazue Kanda ◽  
Satoshi Oikawa ◽  
...  
Keyword(s):  
Body Weight ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Blood Biomarkers ◽  
Analog Scale ◽  
Post Exercise ◽  
Blood Samples ◽  
Exercise Induced ◽  
Potential Biomarkers ◽  
Healthy Males

AbstractDiscovery of blood biomarkers to evaluate exercise-induced muscle damage have attracted many researchers and coaches. This study aimed to determine changes in circulating myomesin 3 fragments as a novel biomarker for exercise-induced muscle damage. Nine healthy males performed 10 sets of 40 repetitions of one-leg calf-raise exercise by the load corresponding to the half of their body weight. Muscle symptoms were evaluated by a visual analog scale (VAS). Blood samples were collected before and 2, 4, 24, 48, 72, and 96 h post-exercise. Plasma myomesin 3 fragments levels were significantly increased at 96 h after the eccentric exercise. The myomesin 3 fragments levels were correlated with other biomarkers of muscle damage and the muscle symptoms. These results suggest that the circulating myomesin 3 fragments levels are potential biomarkers reflecting eccentric exercise-induced muscle damage.

Role of plasma non-esterified fatty acids during and after exercise

1991 ◽  
Vol 81 (3) ◽  
pp. 319-325 ◽  
Author(s):  
M. Walker ◽  
B. G. Cooper ◽  
C. Elliott ◽  
J. W. Reed ◽  
H. Orskov ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Plasma Concentration ◽  
Lipid Oxidation ◽  
Recovery Period ◽  
Low Grade ◽  
Alternative Source ◽  
Post Exercise ◽  
Esterified Fatty Acids ◽  
Acid Analogue ◽  
Exercise Period

1. The importance of circulating non-esterified fatty acids as a substrate during and after low-grade exercise has been examined by using a nicotinic acid analogue to inhibit lipolysis. Seven healthy men received acipimox or placebo on separate occasions. After 90 min, bicycle exercise was performed for 45 min (40% of pre-determined maximum oxygen uptake), followed by a 60 min recovery period. 2. The plasma concentration of non-esterified fatty acids increased during exercise after placebo (320 ± 80 to 630 ± 110 μmol/l) and remained elevated in the post-exercise period. Basal concentrations were lower after acipimox (100 ± 10 μmol/l; P < 0.05); they declined to 60 ± 10 μmol/l during exercise and remained at this level for the rest of the study. 3. Lipid oxidation increased from 0.8 ± 0.1 to 4.2 ± 0.5 mg min−1 kg−1 during exercise after placebo (P< 0.001) and remained elevated in the post-exercise period (1.2 ± 0.1 mg min−1 kg−1). It was lower after acipimox, but still increased from 0.3 ± 0.1 to 2.3 ± 0.2 mg min−1 kg−1 with exercise. Carbohydrate oxidation was increased after acipimox compared with after placebo, but only reached significance during the post-exercise period (P < 0.05). 4. Although acipimox abolished the rise in the plasma concentration of non-esterified fatty acids during exercise, there was only a 50% decrease in the rate of lipid oxidation. This suggests that an alternative source of non-esterified fatty acids makes an important contribution to the supply of lipid for oxidation during exercise. The elevated plasma concentration of non-esterified fatty acids and lipid oxidation after exercise serve to limit the further oxidation of carbohydrate.

Post-Exercise Increase of Lipid Oxidation after a Moderate Exercise Bout in Untrained Healthy Obese Men

2003 ◽  
Vol 35 (2) ◽  
pp. 97-103 ◽  
Author(s):  
F. Marion-Latard ◽  
F. Crampes ◽  
A. Zakaroff-Girard ◽  
I. De Glisezinski ◽  
I. Harant ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Exercise Bout ◽  
Moderate Exercise ◽  
Post Exercise ◽  
Healthy Obese
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