scholarly journals Traditional Chinese Medicine Enema Therapy in a Patient With a Confirmed Negative SARS-CoV-2 Test in the Respiratory Tract but Positive in the Intestinal Tract: A Case Report

2021 ◽  
Vol 9 ◽  
Author(s):  
Yuzhu Dai ◽  
Zhiyou Zhao ◽  
Huajun Zhou ◽  
Dedong Huang ◽  
Jianjun Luo ◽  
...  
Keyword(s):  
Case Report ◽  
Nucleic Acid ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Respiratory Tract ◽  
Intestinal Tract ◽  
Treatment Plan ◽  
Nucleic Acid Test ◽  
Acid Test

We report the case of a 43-year-old man who was infected with SARS-CoV-2 in February 2020 and actively cooperated with treatment in the hospital. During the course of treatment, we found that the respiratory SARS-CoV-2 nucleic acid became negative, but remained positive in the intestinal tract. As a result, we adjusted the treatment plan to include traditional Chinese medicine enema treatment. The patient had negative intestinal SARS-CoV-2 nucleic acid test within 4 days, and the subsequent repeated review of intestinal SARS-CoV-2 nucleic acid was negative, and the virus was undetectable. It is suggested that traditional Chinese medicine enema treatment may be helpful to remove the SARS-CoV-2 in the intestines of patients with COVID-19 infection, and may support the treatment of patients with respiratory SARS-CoV-2 nucleic acid negative and positive in the intestinal tract.

What is the meaning of a nonresolved viral nucleic acid test-reactive minipool?

Transfusion ◽  
2014 ◽  
Vol 55 (2) ◽  
pp. 395-404 ◽  
Author(s):  
Lunan Wang ◽  
Le Chang ◽  
Yunzheng Xie ◽  
Chengyin Huang ◽  
Lei Xu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Viral Nucleic Acid ◽  
Nucleic Acid Test ◽  
Acid Test

A comprehensive review of pharmacokinetic and pharmacodynamic in animals: exploration of interaction with antibiotics of Shuang-Huang-Lian preparations

2021 ◽  
Vol 21 ◽  
Author(s):  
Liuyi Liang ◽  
Xin Jin ◽  
Jinjing Li ◽  
Rong Li ◽  
Xinyi Jiao ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Pharmacokinetic Interaction ◽  
Pharmacological Action ◽  
New Strategy ◽  
System Review ◽  
Tract Infections ◽  
Important Significance

: As a traditional Chinese medicine, Shuang-Huang-Lian (SHL) has been widely used for treating infectious diseases of the respiratory tract such as encephalitis, pneumonia and asthma. During the past few decades, considerable research has focused on the pharmacological action, pharmacokinetic interaction with antibiotics and clinical applications of SHL. A huge and more recent body of pharmacokinetic study supports the combination of SHL and antibiotics has different effects such as antagonism and synergism. SHL has been one of the best-selling traditional Chinese medicine (TCM) products. However, there is no system review of SHL preparations, ranging from protection against respiratory tract infections to interaction with antibiotics. Since their important significance in clinical therapy, the pharmacodynamic, pharmacokinetic, and interactions with antibiotics of SHL were reviewed and discussed. In addition, this review attempts to explore the possible potential mechanism of SHL preparations in prevention and treatment of COVID-19. We are concerned about what is known of the effects of SHL against virus, bacterium, and its interactions with antibiotics, providing a new strategy for expanding the clinical research and medication of SHL preparations.

scholarly journals Cases Report of Cured Novel Coronavirus-infected Pneumonia Patients with Viral Nucleic Acid Test Positive in Fecal Specimens

2020 ◽  
Author(s):  
Mei Han ◽  
Jingbo Zou ◽  
Wenguang Tian ◽  
Xiaoyu Wei ◽  
Yang Zhou ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Molecular Diagnostic ◽  
Clinical Practices ◽  
Rt Pcr ◽  
Viral Nucleic Acid ◽  
Nucleic Acid Test ◽  
Assessment Standard ◽  
Novel Coronavirus ◽  
Acid Test ◽  
Respiratory Specimens

Abstract Background: The outbreak of the novel coronavirus in China (COVID-19) represents a significant and urgent threat to global health. We report here five cases of COVID-19 infection patients in our clinical practices who are medically stable and presumed to successfully “cleared” the virus after antiviral treatments. Case presentation: The clinical evaluation depends on the viral nucleic acid test in respiratory specimens by real-time PCR reverse transcription (RT-PCR) assays according to the authorized guidance. We found that the stool samples of these cured patients remain positive in RT-PCR assay while the virus is undetectable in respiratory specimens. RT-PCR molecular diagnostic assay was designed to specifically detect the presence of viral RNA. Thus, the positive result in the fecal specimens implies the existence of viable virions with the patients. Conclusions: This highlights the importance to look closely at the assessment standard of medical treatment, as well as the need for reevaluation of the criteria for the initial screening, prevention, and care of patients with this emerging infection.

Prevalence and risk factors associated with repeat positive SARS-CoV-2 nucleic acid test results among discharged COVID-19 patients

Medicine ◽  
2021 ◽  
Vol 100 (48) ◽  
pp. e27933
Author(s):  
Yanru Cui ◽  
Jilin Wang ◽  
Gaofeng Wang ◽  
Xiuguo Xie ◽  
Lizhen Tian
Keyword(s):  
Risk Factors ◽  
Nucleic Acid ◽  
Test Results ◽  
Nucleic Acid Test ◽  
Factors Associated ◽  
Acid Test

CRISPR-Cas system meets DNA barcoding: development of a universal nucleic acid test for food authentication

2021 ◽  
pp. 131138
Author(s):  
Yinhuan Wu ◽  
Jun Liu ◽  
Hai-tao Li ◽  
Ting Zhang ◽  
Yi Dong ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Dna Barcoding ◽  
Food Authentication ◽  
Nucleic Acid Test ◽  
Acid Test
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