scholarly journals Pigeons (Columba livia domestica) Are Susceptible to Infectious Bursal Disease: A Comparative Study of Their Hematological and Serum Biochemical Alterations

2021 ◽  
Vol 8 ◽  
Author(s):  
Ochuko Orakpoghenor ◽  
Sunday Blessing Oladele ◽  
Paul Ayuba Abdu ◽  
Talatu Patience Markus ◽  
Samson James Enam ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Columba Livia ◽  
Infectious Bursal Disease ◽  
Total Leukocyte Count ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Serum Total Protein ◽  
Biochemical Alterations ◽  
Bursal Disease ◽  
Serum Biochemical

The hematological and serum biochemical alterations following very virulent infectious bursal disease virus (IBDV) infection in pigeons and chickens were evaluated in this study. Sixty IBDV seronegative birds comprising 30 (3–6 weeks old) pigeons and 30 (3 weeks old) chickens were randomly divided as follows: 10 uninoculated pigeons only, 10 inoculated pigeons + 10 sentinel chickens, 10 inoculated chickens + 10 sentinel pigeons, and 10 uninoculated chickens. Inoculated birds were administered 0.20 ml of inoculum containing very virulent IBDV (vvIBDV). Blood was collected postinoculation/exposure (pi/pe) and processed for hematology and biochemistry. The results revealed significantly (P < 0.05) increased packed cell volume, decreased mean corpuscular hemoglobin (MCH), and MCH concentration (MCHC) in inoculated and sentinel chickens. Total leukocyte count (TLC), heterophil, and heterophil/lymphocyte (H/L) ratio were increased from 3 dpi/dpe in inoculated pigeons and from 3 to 14 dpi/dpe in inoculated and sentinel chickens. At 10 and 14 dpi/dpe, there was significantly (P < 0.05) increased serum total protein and globulin concentrations and decreased albumin/globulin ratio in pigeons and chickens. Serum urea concentration showed significant (P < 0.05) increase in inoculated and sentinel chickens at 3 and 4 dpi/dpe. To the authors' knowledge, this is the first report on hematological and serum biochemical alterations due to vvIBDV infection in pigeons.

Haematology and Blood Chemistry of the Conscious Platypus, Ornithorhynchus anatinus (Shaw) (Monotremata: Ornithorhynchidae)

1984 ◽  
Vol 32 (5) ◽  
pp. 631 ◽  
Author(s):  
RJ Whittington ◽  
TR Grant
Keyword(s):  
Leukocyte Count ◽  
New South ◽  
Blood Chemistry ◽  
Total Leukocyte Count ◽  
Cell Parameters ◽  
Sexual Dimorphisms ◽  
South Wales ◽  
Ornithorhynchus Anatinus ◽  
Serum Biochemical ◽  
The Mean

Blood was collected from a bill sinus of nine conscious adult platypuses, Ornithorhynchus anatinus, caught in south-eastem New South Wales. Sexual dimorphisms were not found in the haematological and serum biochemical values measured. Results were compared with those obtained earlier from anaesthetized platypuses: ether anaethesia did not affect red cell parameters and the majority of biochemical values measured. It did, however, cause significant leukocytosis due to neutrophilia and monocytosis. The mean total leukocyte count in conscious platypuses was 28.63 X 10*9.1-�. The unusually high urea levels and low creatinine levels found in anaesthetized platypus were confirmed in this study (31.5 mmol.l-� and 26 �mol.l-� respectively). High values for erythrocyte count (9.96 X 10*12.l-�), packed cell volume (0.491.l-�) and haemoglobin (190 g.l-�) were found in conscious platypuses, confirming earlier findings and supporting the view that the erythrocyte parameters of the platypus show significant adaptations to hypoxia.

scholarly journals Hematological and serum biochemical findings in clinical cases of cattle naturally infected with lumpy skin disease

2015 ◽  
Vol 9 (03) ◽  
pp. 283-288 ◽  
Author(s):  
Sameeh M Abutarbush
Keyword(s):  
Skin Disease ◽  
Venous Blood ◽  
Hemoglobin Concentration ◽  
Viral Disease ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Creatinine Concentration ◽  
Blood Profile ◽  
Lumpy Skin Disease ◽  
Serum Biochemical

Introduction: Lumpy skin disease (LSD) is an acute viral disease of cattle that is currently emerging in the Middle East region and poses a serious threat to Europe and the rest of the world. The objective of this study was to describe hematological and serum biochemical findings associated with natural clinical infection of LSD in cattle. Methodology: A total of 129 animals clinically infected with LSD were enrolled in the study. Venous blood sample were collected from study animals, and hematological and serum biochemical parameters were measured. Results: Leukocytopenia was found in 8.7%, while leucocytosis was found in 18.2% of affected cattle. Decreased hematocrit concentration was seen in 18.3%. Most affected cattle had reduced mean corpuscular volume (43.7%), mean corpuscular hemoglobin (14.3%), and mean corpuscular hemoglobin concentration (11.5%). All cattle with abnormal platelets count had thrombocytopenia. Hyperfibrinogenemia, hyperproteinemia, and hyperalbuminemia were found in 69%, 59.6%, and 37.2% of affected cattle, respectively. Decreased creatinine concentration was seen in 65.8%. Hyperkalemia and hyperchloremia was found in 9.6% and 10.4% of the affected cattle, respectively. Conclusions: LSD appears to be associated with inflammatory leukogram, anemia, thrombocytopenia, hyperfibrinogenemia, hyperproteinemia, decreased creatinine concentration, hyperchloramia, and hyperkalemia. These are likely due to the associated severe inflammatory process and disease complications such as anorexia and reduced muscle mass. This is the first study that documents hematological and serum biochemical findings associated with LSD infection. Understanding the blood profile picture may give further insight to the pathogenesis of the disease and help in treatment of individual cattle.

scholarly journals Clinico hematological profile of pancytopenia in pediatric patients: an institutional experience in North Himalayan region of India

2020 ◽  
Vol 8 (2) ◽  
pp. 726
Author(s):  
Anil Rawat ◽  
Varun Mamgain ◽  
Smita Chandra ◽  
B. P. Kalra
Keyword(s):  
Bone Marrow ◽  
Aplastic Anemia ◽  
Megaloblastic Anemia ◽  
Nutritional Deficiency ◽  
Deficiency Anemia ◽  
Total Leukocyte Count ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Common Cause ◽  
Nutritional Anemia

Background: Pancytopenia is a common clinical pattern with an extensive differential diagnosis, but literature search shows only limited studies of pancytopenia in Pediatrics patients in Uttarakhand state of India. The present study was therefore conducted to study the spectrum of pancytopenia with bone marrow and haematological profile in Pediatrics patients in this north Himalayan state of India.Methods: Prospective observational study was conducted in the Department of Pediatrics in the teaching institute situated in Uttarakhand state of India over a period of 12 months. The study included all the patients of pancytopenia below 18 years of age who underwent bone marrow examination after written informed consent.Results: The study included total 50 pediatrics patients of pancytopenia with male to female ratio of 1.38:1. The mean age of patients was 10.58±4.94 with median age of 12 years. Mean hemoglobin was 5.31±2.09 g/dl, total leukocyte count was 2492.68±941.76/mm3, platelet count was 34724±26423/mm3, mean corpuscular volume was 90.95±16.65 fl, mean corpuscular hemoglobin was 30.11±6.07 pg, mean corpuscular hemoglobin concentration was 33.06±1.65% and reticulocyte count was 1.21±1.10%. Nutritional deficiency (28%) was the most common cause for pancytopenia followed by aplastic anemia (24%). Megaloblastic anemia was the commonest cause of nutritional deficiency anemia (71.42%) with pancytopenia.Conclusions: Pancytopenia is an important presentation in Pediatrics population with the most common cause being nutritional anemia and aplastic anemia. Megaloblastic anemia is the commonest cause of nutritional anemia with pancytopenia. The clinicians should be aware of spectrum of pancytopenia with clinical and haematological presentation in Pediatrics patients of this region so as to avoid unnecessary work ups and delay in treatment.

scholarly journals Comparative pathological changes in sheep infected with Theileria annulata and non-infected control

2018 ◽  
Vol 68 (4) ◽  
pp. 629
Author(s):  
W. AKHTER ◽  
A. ASLAM ◽  
M. U. REHMAN ◽  
H. U. REHMAN ◽  
I. RASHID ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Hemoglobin Concentration ◽  
Theileria Annulata ◽  
Total Leukocyte Count ◽  
Control Group ◽  
Total Proteins ◽  
Blood Smears ◽  
Healthy Control ◽  
Serum Biochemical ◽  
Peripheral Blood Smears

The hematological, serum biochemical and histopathological variations were compared in sheep naturally infected with Theileria annulata and healthy control group. Peripheral blood smears of 300 suspected sheep were observed for the presence of Theileria by microscopy (24%) and confirmed through PCR (34%). The PCR confirmed samples were used for further studies and showed significant decrease in hemoglobin concentration, packed cell volume (PCV), total erythrocyte counts, total leukocyte count, serum total proteins, creatinine and glucose (P < 0.05) as compared to healthy control. Similarly a significant increase was recorded in Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) (P< 0.05) as compared to non-infected sheep. Histopathological changes revealed edema and severe depletion of lymphocytes in lymph nodes. The present study concluded that ovine theileriosis was linked with some pathological alterations in blood and tissues which could be helpful in the diagnosis of disease.

scholarly journals HEMATOLOGICAL AND SERUM BIOCHEMICAL PROFILE IN EAST BALKAN PIGS AT DIFFERENT AGE AND SEASONS

AGROFOR ◽  
2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Nadezhda PALOVA ◽  
Yordan MARCHEV ◽  
Radka NEDEVA ◽  
Jivko NAKEV ◽  
Dimitrinka KRUSHEVA ◽  
...  
Keyword(s):  
Blood Cells ◽  
Biochemical Parameters ◽  
White Blood Cells ◽  
Age Groups ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Biochemical Profile ◽  
Corpuscular Hemoglobin ◽  
Serum Biochemical ◽  
Serum Biochemical Profile

Twelvehematological and fifteen serum biochemical parameters were determined in indigenous East Balkan pigs at different ages and two seasons. The experiment was carried out in the Scientific Centre of Agriculture- Sredets aiming to characterize the health status of the animals when reared organically. Blood samples were taken from pre-weaned piglets (n=10), growers (n=10) and sows (n=10) in spring and summer. The results were analysed through two way ANOVA to assess the influence of the age, season and their interaction on the hematological and serum biochemical profile of the animals. Both age and season interacted significantly in regard to the red blood cells count (RBC) (P0.001), hemoglobin (HGB) (P0.001) and hematocrit (HCT) (P0.01), as well as in the most biochemical parameters including creatinine(P0.001), total protein (TP) (P0.001), albumin (ALB) (P0.001), alanine aminotransferase (ALT) (P0.001), aspartate aminotransferase (AST) (P0.01), uric acid (UA) (P0.01), Mg (P0.001), triglycerides (TG) (P0.05) and cholesterol (P0.01). Regardless of the season, the white blood cells (WBC) including lymphocytes and granulocytes, as well as platelets (PLT)decreased with age, while mean corpuscular volume (MCV) increased.The content of glucose, urea, gamma-glutamil transferase (GGT), alkaline phosphatase (ALP), Ca and P which displayed maximal values in preweaned pigs (P0.05) compared to the other age groups (P0.05). The season affected the number of lymphocytes (P0.01), their percent (P0.001), mean corpuscular hemoglobin (MCH) andmean corpuscular hemoglobin concentration (MCHC) (P0.001), as well as the concentration of GGT (P0.001) which increased during summer,and also granulocytes (P0.01), their percentage (P0.001), PLT (P0.05), glucose, urea, ALP, Ca (P0.001) and P (P0.01) whichwere higher in spring.

scholarly journals The effect of delivery type on neonatal blood indices in an Iranian population

2018 ◽  
Vol 5 (10) ◽  
pp. 2768-2775 ◽  
Author(s):  
Parastoo Baharvand ◽  
Majid Fathi ◽  
Hossein Eliyasy ◽  
Babak Abdolkarimi ◽  
Ali Asghar Kiani
Keyword(s):  
Cesarean Section ◽  
Pregnant Women ◽  
Hematological Parameters ◽  
Full Term ◽  
Iranian Population ◽  
Total Leukocyte Count ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Distribution Width ◽  
Term Neonates

Background: Generally, there are two methods for childbirth: normal vaginal and cesarean section (C-section). Each method has advantages and complications. In this study, we investigated the effects of type of delivery on hematological parameters in healthy full-term neonates in an Iranian population, from 2016-2017. Materials: Three hundred pregnant women, along with their healthy and term babies, were studied. According to the route of delivery, the neonates were divided into two groups: vaginal (n=150) and C-section (n=150). Complete blood count (CBC) and peripheral blood smear (PBS) were performed on the neonates from umbilical cord blood immediately after birth. Data were analyzed by using SPSS v. 22 and statistical analyses were done by student's t-test and correlation tests, with P-value < 0.05 set as the lowest limit of significance. Results: We observed a significant increase in hematologic parameters, such as red blood cell (RBC) count, hemoglobin, hematocrit, red cell distribution width (RDW), platelets, total leukocyte count and neutrophil count, in full-term neonates who delivered vaginally compared to those delivered by cesarean section (p<0.001). However, there was no significant difference between the delivery types in terms of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean platelet volume (MPV), platelet distribution width (PDW), eosinophil count, lymphocyte count, or monocyte count. Conclusion: According to our study, the mode of delivery influences the hematological parameters in full-term neonates; thrombocytopenia and anemia in neonates were associated with cesarean section delivery. Thus, we recommend that pregnant women do not deliver by C-section unless in emergency situations.  

Comparative Haemato-biochemical and Histopathological Studies in Birds Inoculated with Vaccine and Field Strain of Infectious Bursal Disease Virus

2020 ◽  
Author(s):  
Vandana Gupta ◽  
D. K. Agrawal ◽  
G. K. Mishra ◽  
M. K. Pandey ◽  
P. D.S. Raghuvanshi
Keyword(s):  
Vaccine Strain ◽  
Clinical Signs ◽  
Preventive Measure ◽  
Emerging Diseases ◽  
Field Strain ◽  
Bursa Of Fabricius ◽  
Infectious Bursal Disease ◽  
Live Attenuated Vaccine ◽  
Biochemical Alterations ◽  
Bursal Disease

Background: Infectious bursal disease (IBD) is an economically important disease of birds which is controlled largerly by vaccination with live attenuated vaccine. The virus is more pathogenic in birds above three weeks of age. The problem of immuno-suppression in birds is one of the leading cause of increase in incidences and intensity of already existing diseases and also of new emerging diseases. Vaccination being one of the important preventive measure for IBD has been implicated as a cause of immunosuppression in many instances. This study was designed to compare the haemato-biochemical and gross-histopathological observations after infection with field and vaccine strain in birds below and above three weeks of age. Methods: In birds below and above three weeks of age, field and vaccine strain of IBD virus was inoculated with subsequent study of haemato-biochemical and gross-histopathological changes. Result: Results indicated that vaccine strain used in this study (IV-95 strain) caused a comparable damage with field strain. The bursal body weight index was not a good indicator for IBD pathogenicity. However, the clinical signs were dependent and could be correlated to aspects such as haemato-biochemical alterations, gross and histopathological lesions in organs other than bursa of Fabricius (BF). Bursal changes could not be correlated to clinical signs as the birds lacking frank clinical signs were equally suffering from bursal damage and depletion of lymphocytes. Hence attenuated intermediate invasive strain of vaccine was capable of damaging BF and may be responsible for immunosuppression.

Sign in / Sign up

Export Citation Format

Share Document