scholarly journals Case Report: Spontaneous Appendicitis With Suspected Involvement of Klebsiella variicola in Two Pet Rabbits

2021 ◽  
Vol 8 ◽  
Author(s):  
Vladimir Jekl ◽  
Anna Piskovska ◽  
Ivana Drnkova ◽  
Misa Skoric ◽  
Karel Hauptman ◽  
...  

Although laboratory rabbits are commonly used as models of appendicitis in man, spontaneous appendicitis was only described ante-mortem in one pet rabbit with an acute abdomen. The aim of this article is to describe two spontaneous cases of appendicitis in pet rabbits, to describe therapeutic appendectomy, and to discuss the microbial flora of the inflamed appendix. A 5-month-old intact female and a 16-month-old, neutered male were presented to the veterinary clinic with restlessness, anorexia, and reduced faecal output. The main clinical findings were restlessness, severe discomfort on abdominal palpation, a mid-abdominal palpable tubulous mass and an elevated rectal temperature. Blood analyses showed lymphocytosis, monocytosis, and hyperglycaemia. Radiography was inconclusive. Abdominal ultrasound revealed a presence of a tubular structure with wall thicknesses of 4.2 and 3.7 mm in the two rabbits, respectively. The tubular structure had a rounded, closed end, and a multilayered wall, suggestive of appendicitis. Due to metabolic acidosis and poor prognosis, the first rabbit was euthanized. In the 16-month-old rabbit, appendectomy was performed. Recovery was uneventful, and 4 h after surgery, the rabbit started to become normally active. Postoperative care consisted of fluid therapy, multimodal analgesia, supportive care and prokinetics. Follow-up examinations at 10 days, 1 month, and at 11 months after the surgery did not show any abnormal clinical or laboratory findings. Histopathological examination of appendices from both rabbits showed gangrenous appendicitis. Aerobic cultivation showed the presence of pure culture of Klebsiella variicola sensitive to enrofloxacin, marbofloxacin, tetracycline, cefuroxime, trimethoprim sulphonamide, neomycin, and gentamicin. Restlessness associated with anorexia, abdominal pain, palpable abdominal mass, hyperglycaemia, lymphocytosis, and elevated rectal temperature may be indicative of inflammation within the gastrointestinal tract. Abdominal ultrasound is recommended in rabbits with showing these clinical signs because radiography can be inconclusive. Appendicitis is a life-threatening condition, which should be included into the list of differential diagnoses; for the rabbit, an acute abdomen and gastrointestinal stasis syndrome and must be treated immediately. K. variicola may be associated with appendicitis in rabbits as a causative agent or in association with appendix intraluminal dysmicrobia.

2013 ◽  
Vol 2 (2) ◽  
pp. 20-27 ◽  
Author(s):  
Prakash Sharma ◽  
Sidharth ◽  
BP Singh ◽  
D Singh ◽  
A Gupta

Introduction: Acute abdomen might indicate a progressive intra-abdominal condition that is threatening to life or capable of causing severe morbidity. A good history, thorough clinical examination, laboratory investigations and imaging studies is necessary in order to arrive at a correct diagnosis. The aim of our study was to compare the diagnostic yield of traditional three-view abdominal x-ray series (upright chest x-ray, supine and upright abdominal x-rays) with that of ultrasound in patients presenting with non traumatic acute abdominal surgical pain. Methods: This prospective study was conducted between February and July 2010 on 65 consecutive patients. Critically ill patients, pregnant ladies, patient with trauma abdomen, acute abdomen due to gynaecological pathologies were excluded from our study. Detail abdominal ultrasound was done. After ultrasound traditional three-views acute abdominal x-ray series (AAS) were taken. Final diagnosis was made on the basis of operative findings/therapeutic response/ histopathological/ laboratory findings. Finally, accuracy of clinical diagnosis, plain film and ultrasound in evaluation of acute abdomen was determined. Results: Ultrasound yielded an overall sensitivity and specificity of 78.7% and 84.6.6% respectively. The AAS interpretations yielded an overall sensitivity and specificity of 23.4% and 38.40% respectively. Conclusion: Plain x ray is less sensitive in the evaluation of nontraumatic acute abdomen so it should be used together with ultrasound abdomen in order to arrive at a correct diagnosis. Nepalese Journal of Radiology; Vol. 2; Issue 2; July-Dec. 2012; 20-27 DOI: http://dx.doi.org/10.3126/njr.v2i2.7681


2021 ◽  
Vol 7 (1) ◽  
pp. 205511692199539
Author(s):  
Gordon A Davidson ◽  
Samantha S Taylor ◽  
Melanie J Dobromylskyj ◽  
Francesco Gemignani ◽  
Helen Renfrew

Case summary A 5-year-old neutered male domestic longhair cat was presented for the investigation of a cranial abdominal mass following a 1-month history of inappetence and lethargy. Abdominal ultrasound revealed a large cavitated mass confluent with the mesenteric aspect of the descending duodenum. At surgery, the mass was found to involve the pylorus, proximal duodenum and pancreas, and was non-resectable. Histopathological examination of surgical biopsies revealed a non-neoplastic process involving eosinophils and fibroplasia. Relevance and novel information This case report describes an uncommon feline gastrointestinal pathology with an unusual appearance that may provide an additional differential diagnosis other than neoplasia or abdominal abscess when confronted with a cavitated abdominal mass in cats.


2021 ◽  
Vol 14 (2) ◽  
pp. 142-144
Author(s):  
Alex dos Santos ◽  
◽  
Mariana Martins ◽  

Clinical History: This 8-month-old, male, mixed breed domestic shorthaired cat had a recent history of acute apathy and anorexia. It remained under hospital care for two days, during which it did not produce any urine. On the second day of hospitalization, another cat from the same household was brought in with similar clinical signs. These cats did not have any history of recent ingestion of antibiotics or other medication. Furthermore, they did not have any street or yard access since they were kept in an apartment. Both cats died spontaneously after a brief hospitalization period. Laboratory Findings: Marked increase of urea and creatinine in both cats was reported (values not informed). On abdominal ultrasound, both cats had perirenal edema, and small amount of free abdominal effusion was observed in this cat. Necropsy Findings: There was moderate amount of translucent, slightly yellowish fluid within the abdominal cavity, thoracic cavity and pericardial sac. There was moderate diffuse pulmonary edema. Moderate perirenal edema was observed bilaterally. The kidneys were diffusely swollen and pale (Fig. 1). On histopathologic exam, the cortical tubular epithelial cells were swollen, with hypereosinophilic cytoplasm and nuclear changes (karyolysis, pyknosis and karyorrhexis). These cells were frequently detached from the basement membrane. Some other tubular epithelial cells were swollen and markedly vacuolated. Accompanying these changes, multiple granular casts filled the tubular lumens in the cortical and medullar regions (Fig. 2).


2018 ◽  
Vol XXIII (132) ◽  
pp. 56-64
Author(s):  
Sayonara da Luz Ferro ◽  
Ewerton Cardoso ◽  
Fernanda Jönck ◽  
Marta Cristina Thomas Heckler ◽  
Bruna Warmlin ◽  
...  

Hemangioma is a benign, noninvasive and non-metastatic neoplasm originating from endothelial cells of the blood vessels. The involvement of the urinary vesicle with neoplasias occurs in less than 0.5% of dogs. The main clinical signs are hematuria, dysuria, pollakiuria, incontinence and urinary obstruction. The diagnosis is based on imaging tests and is confirmed by histopathological examination. The treatment of choice is surgical resection with safety margins. This paper reports the case of a twelve-year-old Poodle with a history of abdominal pain, which was attended at the Florianópolis Veterinary Hospital. Abdominal ultrasound showed the presence of free fluid. During exploratory laparotomy, the urinary vesicle was observed to be ruptured, presenting a thickened wall and small areas of necrosis. A sample was sent for histopathological analysis and the diagnosis was of benign vascular neoplasia compatible with hemangioma.


2020 ◽  
Vol 8 (3) ◽  
pp. e001123
Author(s):  
Emily Tryon ◽  
Alexandra Kalamaras ◽  
Ching Yang ◽  
Vincent Wavreille ◽  
Laura Elizabeth Selmic

This report details a cat with a duodenal duplication cyst in the region of the right distal pancreas. The cat presented with vomiting, anorexia, pancreatitis and a palpable abdominal mass that was visible on abdominal ultrasound as a thick-rimmed, cavitated structure with echogenic contents. As such, an initial clinical diagnosis of pancreatic abscess or cyst was suspected. After an exploratory coeliotomy to assess the lesion, a definitive diagnosis of duodenal duplication cyst was determined based on the histopathological findings of a wall with features of the intestinal tract and no communication with the intestinal lumen. The clinical signs, physical examination findings and advanced imaging characteristics of pancreatic abscess and duodenal duplication cyst are discussed in this report to aid clinicians with differentiating between these two rare lesions.


2020 ◽  
Vol 8 (3) ◽  
pp. e001138
Author(s):  
Sarrah Kaye

An 11-year-old, reproductively active female Bolivian grey titi monkey (Plecturocebus donacophilus) in a zoological institution was presented for abdominal distension without concurrent clinical signs. Physical examination and imaging studies detected a uterine mass. Preoperative bloodwork revealed anaemia and hyperglobulinaemia. Hysterectomy was performed, but the patient died under anaesthesia. Histopathological examination found a chronic uterine abscess with effacement of the uterine wall and generalised inflammation consistent with sepsis. This case documents an uncommon reproductive tract lesion in a New World primate, and demonstrates the value of routine reproductive health monitoring in non-human primates, as not all pathologies will have clinical signs perceptible by caretakers. Earlier diagnosis may have resulted in an improved outcome in this case. Uterine abscess could be a differential diagnosis in cases of abdominal mass effect or distension in female titi monkeys.


2020 ◽  
Vol 8 (1) ◽  
pp. e000948
Author(s):  
Kyriakos Chatzimisios ◽  
Michael Patsikas ◽  
Vasileia Angelou ◽  
Ioanna Tragoulia ◽  
Lysimachos G Papazoglou

Two dogs presented with chronic vomiting and an abdominal mass, respectively, for further investigation and treatment. Abdominal ultrasound revealed an intramural intestinal mass with a core of strongly echogenic interfaces surrounded by a rim of soft tissue echogenicity in one of the dogs and a well-demarcated soft tissue echogenicity mass in the other dog. Abdominal CT revealed an intramural intestinal mass with air attenuating centre surrounded by a soft tissue-attenuating rim in one of the dogs and a well-demarcated soft tissue-attenuating mass in the other dog. Abdominal exploration revealed a retained sponge within the intestine of one of the dogs and a sponge that adhered to the jejunum in the other dog. One of the dogs underwent intestinal resection and the other had a mass resection. One of the dogs was euthanatised due to an anastomotic leak and secondary peritonitis, and the other was free of clinical signs of abdominal disease 1 year after surgery.


2016 ◽  
Vol 42 (01) ◽  
pp. 35-39 ◽  
Author(s):  
Roh-Kyum Lee ◽  
Yu-Lun Tsai ◽  
Hui-Ju Wang ◽  
Cheng-Chung Lin ◽  
Shih-Chieh Chang ◽  
...  

A three-year-old female intact albino ferret was presented with clinical signs of panting, hyperpnea, weakness in all four limbs, loss of the swallowing reflex, lockjaw and sudden paleness of the oral mucosa and extremities. An abdominal mass was discovered during palpation. The patient died suddenly after clinical signs were observed. At necropsy, hemoperitoneum was noted in the abdominal cavity and a [Formula: see text][Formula: see text]cm dark red moruloid mass was found in the mesentery of the ileum. Histopathological examination of the mass revealed multiple cavernous structures with significant blood accumulation. Oval to polygonal neoplastic cells with frequent mitotic figures were also noted. Furthermore, neoplastic cells were positively stained with antibodies of CD34 and Factor VIII, and had metastasized to the mesentery lymph nodes. The definitive diagnosis was visceral hemangiosarcoma in a ferret.


2017 ◽  
Vol 45 ◽  
pp. 4
Author(s):  
Ana Paula Fauth Bohrer ◽  
Franciele Rossi Dos Santos ◽  
Carla Jenifer Sperhacke ◽  
Francie Rasador ◽  
André Felipe Streck ◽  
...  

Background: The multilobular tumor of bone, also known as chondroma rodens, is a primary tumor of bones with low frequency in dogs. It is considered a slow-growth malignant tumor, locally invasive, able to compress and invade the cerebral tissue. Its occurrence is greater in the flat bones of skull and hard palate. The clinical signs depend on the tumor location and usually are related to the compression of adjacent structures. The aim of this study is present a multilobular tumor of bone clinical case in a dog with has progressive growth on the skull’s frontal part and facial deformation. Clinical, laboratory and therapeutic findings will be discussed in the report.Case: An 8-year-old male crossbred castrated dog, weighing 31 kg, presenting progressive growth in the skull was examined at the University of Caxias do Sul veterinary clinic. According to the owner, the tumor was firstly observed about 3 months ago, and the dog became prostrated since then. In the clinical examination, was noticed an enlarged, symmetric and diffuse volume in the skull’s frontal part, facial deformation, especially around the ocular region, causing visual deficit. It wasn’t detected any other systemic alterations. The radiography of the skull revealed a soft tissue increased volume, suggesting a mass or an encapsulated abscess. Serum biochemistry demonstrated an increase of alcaline phosphatase activity. The other hematological and biochemical parameters were within normal limits. Fine needle aspiration was performed, showing compatible result with bone neoplasm. It was chosen to make a surgical resection, starting with a cross-shaped incision on medial portion of the skull, followed by a skin disclosure to expose the tumor. With the assistance of an orthopedical chisel and metzembaum scissors, the mass was removed. The tumor presented steady and sanded aspect, reddish colored with whitish areas. Due to the anatomic area and evolved structures, it was not possible to make the total removal of the tumor with a safety margin. Fragments were sent to histopathological examination, and the final diagnosis was multilobular tumor of bone. After hospital discharge, antibiotic cefalexin and analgesia was prescribed tramadol hydrochloride and carprofen. Weekly follow-up and reviews were performed, with points with drawn within 15 days. One month after the surgery, the dog came back to the review feeling prostrated and presenting a new mass (in the same location), causing him once more visual deficit. The owner opted to euthanize, not authorizing necropsy.Discussion: The multilobular tumor of bone is considered a slow-growth malignant tumor that usually occurs on the dog’s skull. The clinical signs are related to the compression of the affected structures. In this case, the animal has visual deficit due to the mass growth above ocular region. The multilobular tumor of bone is considered rare in dogs, however it is important to know this disease manifestations, allowing the best intervention to be done. It is important to emphasize that the cytological findings are similar of those on osteosarcoma, so it is considered as a differential diagnosis. The histopathological examination is indispensable to make the final diagnosis. The surgical resection may provide better quality of life and longer survival and must be evaluated according to each case.


2021 ◽  
Vol 162 (3) ◽  
pp. 112-115
Author(s):  
Tímea Seszták ◽  
Attila Kálmán ◽  
Áron Cseh ◽  
Péter Krivácsy ◽  
Tamás Micsik ◽  
...  

Összefoglaló. Az appendectomia szövődményei a leggyakrabban a korai posztoperatív időszakban jelentkeznek. A műtét után évekkel megjelenő szövődmény ritka. Egy 11 éves kislányt vizsgáltunk 2 hete fennálló hasi panaszok miatt. Anamnézisében 8 évvel ezelőtt hagyományos módon elvégzett appendectomia szerepel. Az Ausztriában készült első hasi ultrahangvizsgálat eltérést nem talált. Az intézetünkben elvégzett képalkotó vizsgálatok – hasi ultrahang, MR-vizsgálat – ileocoecalisan elhelyezkedő szolid terimét igazoltak, és felvetették a folyamat gyulladásos eredetét. A szerteágazó klinikai tünetek, a laboratóriumi és a képalkotó diagnosztikai eltérések kapcsán differenciáldiagnosztikai szempontból a gyulladásos bélbetegség lehetősége is felmerült, és biztonsággal a tumoros folyamatot sem sikerült kizárni. A rosszabbodó status miatt műtét történt. Ennek során a colon ascendenssel összefüggő, makroszkóposan tumoros megjelenésű elváltozást távolítottak el. A szövettani vizsgálat malignitást nem igazolt, a folyamat idegen test okozta – varróanyag-granuloma – krónikus gyulladásos jellegét erősítette meg. A vizsgálatok kapcsán coeliakia is igazolódott. A hasi műtétek ritka szövődménye a Schloffer-tumor, melyet idegen test típusú – gyakran sebészi varróanyag-maradvány körüli – granulomatosus gyulladásos folyamat jellemez. Az entitás ismerete differenciáldiagnosztikai szempontból fontos. Nehezítette a diagnózist az első hasi ultrahangvizsgálat negatív eredménye és az egyidejűleg manifesztálódó coeliakia. Orv Hetil. 2021; 162(3): 112–115. Summary. Generally, complications with appendectomy occur during the early postoperative stage and are quite rare years after the operation. In case of late manifestation of complications, the clinical signs are generally unspecific. We report a case of an 11-year-old girl – who underwent an appendectomy 8 years ago – with abdominal pain during the last 2 weeks. The first ultrasound examinations were carried out in Austria with normal results. In our department, the ultrasonography and the MR examinations showed an inhomogeneous abdominal mass which was connected to the abdominal wall and with the suspicion of inflammation. Because of the diversified results of radiology imaging and laboratory test, inflammatory bowel disease and tumor were considered in the differential diagnosis. During the operation, a tumor-like lesion related to the ascending colon was found. The histopathological examination revealed a foreign body type suture granuloma with a central abscess. Malignancy was not found. The clinical investigation proved celiac disease, too. The Schloffer tumor is a rare complication after abdominal surgery. This is a foreign body type inflammatory granuloma mainly around a surgical thread. The knowledge of the entity is important in differential diagnostic aspect. The presence of celiac disease in combination with the negative result of the first ultrasound examination made the exact diagnosis more difficult. Orv Hetil. 2021; 162(3): 112–115.


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