scholarly journals Endocrine Fertility Parameters—Genomic Background and Their Genetic Relationship to Boar Taint in German Landrace and Large White

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 231
Author(s):  
Ines Brinke ◽  
Christine Große-Brinkhaus ◽  
Katharina Roth ◽  
Maren Julia Pröll-Cornelissen ◽  
Sebastian Klein ◽  
...  
Keyword(s):  
Genetic Relatedness ◽  
Genetic Relationships ◽  
Young Male ◽  
Boar Taint ◽  
Genetic Progress ◽  
Large White ◽  
Genome Wide ◽  
A Genome ◽  
Different Origins ◽  
Fertility Traits

The surgical castration of young male piglets without anesthesia is no longer allowed in Germany from 2021. One alternative is breeding against boar taint, but shared synthesis pathways of androstenone (AND) and several endocrine fertility parameters (EFP) indicate a risk of decreasing fertility. The objective of this study was to investigate the genetic background between AND, skatole (SKA), and six EFP in purebred Landrace (LR) and Large White (LW) populations. The animals were clustered according to their genetic relatedness because of their different origins. Estimated heritabilities (h2) of AND and SKA ranged between 0.52 and 0.34 in LR and LW. For EFP, h2 differed between the breeds except for follicle-stimulating hormone (FSH) (h2: 0.28–0.37). Both of the breeds showed unfavorable relationships between AND and testosterone, 17-β estradiol, and FSH. The genetic relationships (rg) between SKA and EFP differed between the breeds. A genome-wide association analysis revealed 48 significant associations and confirmed a region for SKA on Sus Scrofa chromosome (SSC) 14. For EFP, the results differed between the clusters. In conclusion, rg partly confirmed physiologically expected antagonisms between AND and EFP. Particular attention should be spent on fertility traits that are based on EFP when breeding against boar taint to balance the genetic progress in both of the trait complexes.

scholarly journals Genomic background and genetic relationships between boar taint and fertility traits in German Landrace and Large White

BMC Genetics ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Ines Brinke ◽  
Christine Große-Brinkhaus ◽  
Katharina Roth ◽  
Maren J. Pröll-Cornelissen ◽  
Hubert Henne ◽  
...  
Keyword(s):  
Genetic Relationships ◽  
Boar Taint ◽  
Large White ◽  
Fertility Traits

A genome‐wide association study reveals additive and dominance effects on growth and fatness traits in large white pigs

2021 ◽  
Vol 52 (5) ◽  
pp. 749-753
Author(s):  
W. Yang ◽  
J. Wu ◽  
J. Yu ◽  
X. Zheng ◽  
H. Kang ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Large White ◽  
Genome Wide ◽  
A Genome

New evidence on the relationship between Microsporidia and Fungi: a genome-wide analysis by DarkHorse software

2014 ◽  
Vol 60 (9) ◽  
pp. 557-568 ◽  
Author(s):  
Heng Xiang ◽  
Ruizhi Zhang ◽  
David De Koeyer ◽  
Guoqing Pan ◽  
Tian Li ◽  
...  
Keyword(s):  
Genetic Relationships ◽  
Enterocytozoon Bieneusi ◽  
Entire Genome ◽  
Encephalitozoon Intestinalis ◽  
Genome Wide ◽  
A Genome ◽  
Fungal Genes ◽  
Eukaryotic Organisms ◽  
New Evidence ◽  
The Relationship

Microsporidia are a group of obligate intracellular eukaryotic parasites that infect a wide variety of species, including humans. Phylogenetic analysis indicates a relationship between the Microsporidia and the Fungi. However, most results are based on the analysis of relatively few genes. DarkHorse analysis involves the transformation of BLAST results into a lineage probability index (LPI) value and allows for the comparison of genes for an entire genome with those of other genomes. Thus, we can see which genes from the microsporidia score most closely based on the LPI with other eukaryotic organisms. In this analysis, we calculated the LPI for each gene from the genomes of 7 Microsporidia, Antonospora locustae, Enterocytozoon bieneusi, Encephalitozoon cuniculi, Encephalitozoon intestinalis, Nosema bombycis, Nosema ceranae, and Nematocida parisii, to analyze the genetic relationships between Microsporidia and other species. It was found that many (91%) genes were most closely correlated with genes from other microsporidial genomes and had the highest mean LPI (0.985), indicating a monophyletic origin of the Microsporidia. In a subsequent analysis, we excluded the other Microsporidia from the analysis to look for relationships before the divergence of Microsporidia, and found that 43% of the microsporidial genes scored highest with fungal genes, and a higher mean LPI was found with Fungi than with other kingdoms, suggesting that Microsporidia is closely related to Fungi at the genomic level. Microsporidial genes were functionally clustered based on the KOG (Eukaryotic COG) database, and the possible lineages for each gene family were discussed in concert with the DarkHorse results.

Detection of quantitative trait loci for locomotion and osteochondrosis-related traits in Large White ✕ Meishan pigs

2003 ◽  
Vol 76 (2) ◽  
pp. 155-165 ◽  
Author(s):  
G.J. Lee ◽  
A.L. Archibald ◽  
G.B. Garth ◽  
A.S. Law ◽  
D. Nicholson ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Chromosome 1 ◽  
Chromosome 15 ◽  
Large White ◽  
Chromosome 13 ◽  
Genome Wide ◽  
A Genome ◽  
Trait Loci ◽  
Gait Score

AbstractData from the F2 generation of a Large White (LW) ✕ Meishan (MS) crossbred population were analysed to detect quantitative trait loci (QTL) for leg and gait scores, osteochondrosis and physis scores. Legs, feet and gait score were assessed in 308 F2 animals at 85 ( + 5) kg and osteochondrosis and physis scores were recorded for the right foreleg after slaughter. A genome scan was performed using 111 genetic markers chosen to span the genome that were genotyped on the F2 animals and their F1 parents and purebred grandparents. A QTL on chromosome 1 affecting gait score was significant at the genome-wide significance level. Additional QTL significant at the chromosome-wide 5% threshold level (approx. equivalent to the genome-wide suggestive level) were detected on chromosome 1 for front feet and back legs scores, on chromosome 13 for front legs and front feet scores, on chromosome 14 for front legs, front feet and back legs scores and on chromosome 15 for back feet score. None of the QTL for osteochondrosis score exceeded the chromosome-wide suggestive level, but one chromosome-wide QTL for physis score was found on chromosome 7. On chromosome 1, gait and front feet scores mapped to the middle of the chromosome and showed additive effects in favour of the LW alleles and no dominance effects. The QTL for back legs score mapped to the distal end of the chromosome and showed a dominant effect and no additive effect. On chromosomes 14 and 15, the LW allele was again superior to the MS allele. On chromosome 13, there were both additive and dominance effects in favour of the MS allele. The MS alleles on chromosome 13 may have potential for introgression into a commercial LW population. The other putative QTLs identified may have value in marker-assisted selection in LW or MS-synthetic populations.

Effects of exogenous porcine somatotropin on performance, testicular steroid production and fat levels of boar-taint-related compounds in young boars

1992 ◽  
Vol 72 (3) ◽  
pp. 537-545 ◽  
Author(s):  
M. Bonneau ◽  
W. J. Meadus ◽  
E. J. Squires
Keyword(s):  
Feed Efficiency ◽  
Genital Tract ◽  
Young Male ◽  
Live Weight ◽  
Boar Taint ◽  
Large White ◽  
Hormone Synthesis ◽  
Porcine Somatotropin ◽  
Young Boars ◽  
Related Compounds

Large White × Pietrain boars were administered 0 or 5 mg recombinant porcine somatotropin (pST) daily between 68 and 105 kg live weight in an investigation of the effects of pST treatment on growth performance, carcass traits, genital-tract development, steroid-hormone synthesis, and fat skatole and androstenone levels in young male pigs. Growth rate was not affected by pST treatment, daily feed intake was decreased 9% (P < 0.05), and feed efficiency was improved 7% (P < 0.01). Muscle content of the carcass was increased from 57.7% to 59.7%, and fat content was reduced from 18.8% to 15.7% (P < 0.001). Genital-tract development, testicular androgen and 16-androstene biosynthesis rates and skatole levels in fat were not affected by pST treatment. Androstenone levels in fat were reduced from 0.66 μg g−1 in control animals to 0.35 μg g−1 in pST-treated animals (P < 0.001). The results of the present experiment indicate that pST treatment of boars of a lean genotype significantly improves the performance of the animals and may contribute to a reduction in the incidence of boar taint. Key words: Boar taint, somatotropin, skatole, androstenone, pigs

Genetic analysis of fertility traits in Jersey crossbred cows

2017 ◽  
Author(s):  
Anshuman Kumar ◽  
Ajoy Mandal ◽  
A. Gupta ◽  
M. Karunakaran ◽  
S. Das ◽  
...  
Keyword(s):  
Management Practices ◽  
Genetic Relationships ◽  
Random Effect ◽  
Reproductive Traits ◽  
Calving Interval ◽  
Genetic Progress ◽  
Factors Affecting ◽  
Service Period ◽  
Parity Number ◽  
Fertility Traits

The present study was carried out to evaluate the genetic and non-genetic factors affecting fertility traits viz., number of service per conception (NSPC), service period (SP) and calving interval (CI) and genetic and phenotypic parameters of these traits in Jersey crossbred cattle, maintained at Eastern Regional Station of ICAR-National Dairy Research Institute, Kalyani, West Bengal over a period of 39 years (1976-2014). The least squares means for the NSPC, SP and CI were 1.73±0.08 inseminations, 156.37±7.47 days and 458.32±9.56 days respectively. The study revealed that all the traits were decreasing significantly with parity number. Season was important in determining service period, whereas period of calving influenced calving interval in this study. NSPC, SP and CI did not differ significantly among different genetic groups; but, half-breds of Jersey and Tharparkar (½ Jersey-½ Tharparkar) showed comparatively lower NSPC, SP and CI than half-breds of Jersey and Red Sindhi and other crosses in this study. The random effect of sire was highly significant on all the fertility traits considered in this study. Heritability estimates for NSPC, SP and CI were 0.08±0.06, 0.18±0.08 and 0.16±0.08 respectively. All the three analyzed traits had close genetic relationships. Low to moderate heritability of reproductive traits indicates slow genetic progress through selection and further improvement in reproductive performance can be made either by better management practices or including large number of polymorphic markers associated with fertility in the population to assist animal selection

scholarly journals A Genome-Wide Association Study in Large White and Landrace Pig Populations for Number Piglets Born Alive

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0117468 ◽  
Author(s):  
Sarah Bergfelder-Drüing ◽  
Christine Grosse-Brinkhaus ◽  
Bianca Lind ◽  
Malena Erbe ◽  
Karl Schellander ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Large White ◽  
Genome Wide ◽  
A Genome ◽  
Landrace Pig

scholarly journals Genome-wide investigation and expression profiling of polyphenol oxidase (PPO) family genes uncover likely functions in organ development and stress responses in populus trichocarpa

2021 ◽  
Author(s):  
Fang He ◽  
Yu-Jie Shi ◽  
Qian Zhao ◽  
Kuang-Ji Zhao ◽  
Xing-Lei Cui ◽  
...  
Keyword(s):  
Polyphenol Oxidase ◽  
Stress Responses ◽  
Populus Trichocarpa ◽  
Expression Patterns ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Genetic Progress ◽  
Element Analysis ◽  
Genome Wide ◽  
A Genome

Abstract Background: Trees such as Populus are planted extensively for reforestation and afforestation. However, their successful establishment greatly depends upon ambient environmental conditions and their relative resistance to abiotic as well as biotic stress. Polyphenol oxidase (PPO) is a ubiquitous metalloproteinase in plants, which plays crucial roles in plant resistance against biotic and abiotic stresses. Although the whole genome sequence of populus trichocarpa has long been published, little is known about the PPO genes in Populus, especially those related to drought stress, mechanical damage, insect feeding and hormone response at the whole genome level. Results: In the recent research, a genome-wide analysis of the Poplar PPOs family was finished and 18 PtrPPOs gene were identified. Then, bioinformatics and qRT-PCR were applied to analyze the gene structure, phylogeny, chromosomal localization, gene replication, Cis-elements, expression patterns of PtrPPOs. Sequence analysis revealed that 2/3 of the PtrPPO genes not contained introns. Phylogenetic analysis revealed that all PPOs gene were split into 11 subfamilies, and woody plants differentiated a large number of PPO genes. 18 PtrPPOs gene were disproportionally apportioned on 19 chromosomes, and the number of three pairs of segmented replication genes and four tandem repeat genomes were detected in poplars. Cis-acting element analysis identified a large number elements of growth and development, secondary metabolism process, and stress-related elements on the promoters of different PPO members. Furthermore, PtrPPO genes were expressed preferably in young plant tissues and fruits. In addition, some PtrPPOs could be significantly induced by PEG, ABA and JA, thus revealing their potential role in regulating stress response. Conclusions: Comprehensive analysis is helpful to select candidate PPO genes for the follow-up study of the biological function, and molecular genetic progress of stress resistance in forest trees provides genetic resources.

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