scholarly journals Unusual Localization of Pennella sp. in Swordfish (Xiphias gladius) Hearts

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1757
Author(s):  
Davide Mugetti ◽  
Elena Colombino ◽  
Vasco Menconi ◽  
Fulvio Garibaldi ◽  
Walter Mignone ◽  
...  
Keyword(s):  
Marine Mammals ◽  
Pelagic Fish ◽  
Genetic Identification ◽  
Wall Thickening ◽  
Histopathological Analysis ◽  
Aquatic Species ◽  
Atrial Wall ◽  
Internal Organs ◽  
Xiphias Gladius ◽  
Species Inquirendae

The genus Pennella comprises hematophagous parasites of marine aquatic species, including cephalopods, marine mammals, and pelagic fish. Nine species have been officially included in the genus Pennella plus another six species inquirendae. They are most often found in the host’s musculature, without penetrating internal organs. For the present study, 83 hearts from swordfish (Xiphias gladius) caught in the Mediterranean Sea were sampled and immediately fixed in formalin for histopathological analysis. In total, 10 (12.05%) hearts were found to be parasitized by copepods of the genus Pennella. Macroscopically, there was mild-to-severe fibrinous pericarditis with atrial wall thickening and multiple parasitic nodules. Histologically, the parasitic nodules were surrounded by an inflammatory-necrotizing reaction. Parasitic infestation by Pennella spp. is common in pelagic fish and in swordfish, in particular. Here, however, we report atypical cardiac localization. A future area of focus is the evaluation of cardiac Pennella spp. infestation by histopathology and genetic identification of the parasites.

scholarly journals Suicide by intoxication with iron (III) chloride

2021 ◽  
Author(s):  
Sławomir Majdanik ◽  
Barbara Potocka-Banaś ◽  
Sebastian Glowinski ◽  
Krzysztof Borowiak
Keyword(s):  
Prussian Blue ◽  
Chloride Ions ◽  
Iron Chloride ◽  
Histopathological Analysis ◽  
Fatal Intoxication ◽  
Internal Organs ◽  
Specific Staining ◽  
Iron Supplements ◽  
Staining Protocol ◽  
Hematoxylin And Eosin

Abstract Purpose Cases of iron intoxication are not very often encountered in toxicology practice, and most of those reported concern accidental intoxications with iron supplements in young children. The paper presents a rare case of a suicide by intoxication in an adult woman who ingested a solution of iron (III) chloride. Methods A forensic was at the Department of Forensic Medicine, PMU in Szczecin. Toxicology tests of blood sampled from the deceased were performed using a 644 CIBA CORNING ion selective analyzer and proprietary reagent kits. Histopathological was with the use of the standard staining protocol (hematoxylin and eosin) and staining specific for iron (Prussian blue). Results Autopsy revealed a distinct yellow discolouration and thrombotic necrosis of the oral mucosa and almost the whole gastrointestinal tract, as well as similar changes in the adjacent internal organs. Considerably high levels of iron and chloride ions were detected in specimens of internal organs preserved during autopsy. Histopathological analysis performed with the use of staining specific for iron (Prussian blue) also confirmed the presence of iron in the examined tissues, especially in the intestines and liver. Conclusions Considering the above findings, it was concluded in the forensic report that the death of the woman was caused by the ingestion of iron chloride. The reported case of fatal intoxication is one of the few described in the literature, and its course implies that in the case of initially diagnosed intoxication with corrosive compounds, the possibility of using metal-containing poison should also be considered in the differential diagnosis. In addition to routine toxicological tests performed in fatal cases we also draw attention to the possibility of using specific staining protocols for microscopic specimens.

MS1-type bioengineered spider silk nanoparticles do not exhibit toxicity in an in vivo mouse model

Nanomedicine ◽  
2021 ◽  
Author(s):  
Tomasz Deptuch ◽  
Anna Florczak ◽  
Anna Lewandowska ◽  
Ewa Leporowska ◽  
Karolina Penderecka ◽  
...  
Keyword(s):  
Spider Silk ◽  
Complete Blood Count ◽  
Growth Factor Receptor ◽  
Histopathological Analysis ◽  
Internal Organs ◽  
Toxicological Evaluation ◽  
Epidermal Growth ◽  
And Behavior ◽  
And Control

Background: Due to factors such as silk sequence, purification, degradation, morphology and functionalization, each silk variant should be individually tested for potential toxicity. Aim:   In vivo toxicological evaluation of the previously characterized bioengineered H2.1MS1 spider silk particles that can deliver chemotherapeutics to human epidermal growth factor receptor 2-positive breast cancer. Materials & methods: Silk nanoparticles (H2.1MS1 and control MS1) were administered intravenously to mice, and then the organismal response was assessed. Several parameters of acute and subchronic toxicity were analyzed, including animal mortality and behavior, nanosphere biodistribution, and histopathological analysis of internal organs. Also, the complete blood count, as well as the concentration of biochemical parameters and cytokines in the serum, were examined. Results & conclusion: No toxicity of the systemically administrated silk nanosphere was observed, indicating their potential application in biomedicine.

scholarly journals Extramammary Paget’s Disease in the Pubic Region: a Case Report

2013 ◽  
Vol 5 (4) ◽  
pp. 171-176
Author(s):  
Slobodan Stojanović ◽  
Nada Vučković ◽  
Pavle Jeremić ◽  
Biljana Jeremić
Keyword(s):  
Case Report ◽  
Private Practice ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Histopathological Analysis ◽  
Extramammary Paget’S Disease ◽  
Incisional Biopsy ◽  
Definite Diagnosis ◽  
Internal Organs ◽  
Extramammary Paget's Disease

Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues.

scholarly journals Illegal, Unreported, and Unregulated Fisheries Threatening Shark Conservation in African Waters Revealed from High Levels of Shark Mislabelling in Ghana

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1002
Author(s):  
Narkie Akua Agyeman ◽  
Carmen Blanco-Fernandez ◽  
Sophie Leonie Steinhaussen ◽  
Eva Garcia-Vazquez ◽  
Gonzalo Machado-Schiaffino
Keyword(s):  
Public Awareness ◽  
Pelagic Fish ◽  
Genetic Identification ◽  
Coi Gene ◽  
Shark Species ◽  
Cytochrome C Oxidase I ◽  
Fish Products ◽  
Iuu Fishing ◽  
Isurus Oxyrinchus ◽  
Shark Conservation

Mislabelling of fish and fish products has attracted much attention over the last decades, following public awareness of the practice of substituting high-value with low-value fish in markets, restaurants, and processed seafood. In some cases, mislabelling includes illegal, unreported, and unregulated (IUU) fishing, contributing to overexploit substitute species that are undetectable when sold under wrong names. This is the first study of DNA barcoding to assess the level of mislabelling in fish marketed in Ghana, focusing on endangered shark species. Genetic identification was obtained from 650 base pair sequences within the cytochrome c oxidase I (COI) gene. All except one of 17 shark fillets analysed were wrongly labelled as compared with none of 28 samples of small commercial pelagic fish and 14 commercial shark samples purchased in Europe. Several substitute shark species in Ghana are endangered (Carcharhinus signatus and Isurus oxyrinchus) and critically endangered (Squatina aculeata). Shark products commercialized in Europe (n = 14) did not reveal mislabelling, thus specific shark mislabelling cannot be generalized. Although based on a limited number of samples and fish markets, the results that reveal trade of endangered sharks in Ghana markets encourage Ghanaian authorities to improve controls to enforce conservation measures.

scholarly journals Effect of left atrial hypertrophy on P-wave morphology in a computational model

2016 ◽  
Vol 2 (1) ◽  
pp. 603-606 ◽  
Author(s):  
Robin Andlauer ◽  
Axel Loewe ◽  
Olaf Dössel ◽  
Gunnar Seemann
Keyword(s):  
Wall Thickness ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
P Wave ◽  
Wall Thickening ◽  
Atrial Wall ◽  
Left Atrial Enlargement ◽  
Left Atrial Wall ◽  
Atrial Enlargement ◽  
Wave Morphology

AbstractP-wave assessment is frequently used in clinical practice to recognize atrial abnormalities. However, the use of P-wave criteria to diagnose specific atrial abnormalities such as left atrial enlargement has shown to be of limited use since these abnormalities can be difficult to distinguish using P-wave criteria to date. Hence, a mechanistic understanding how specific atrial abnormalities affect the P-wave is desirable. In this study, we investigated the effect of left atrial hypertrophy on P-wave morphology using an in silico approach. In a cohort of four realistic patient models, we homogeneously increased left atrial wall thickness in up to seven degrees of left atrial hypertrophy. Excitation conduction was simulated using a monodomain finite element approach. Then, the resulting transmembrane voltage distribution was used to calculate the corresponding extracellular potential distribution on the torso by solving the forward problem of electrocardiography. In our simulation setup, left atrial wall thickening strongly correlated with an increased absolute value of the P-wave terminal force (PTF) in Wilson lead V1 due to an increased negative amplitude while P-wave duration was unaffected. Remarkably, an increased PTF-V1 has often been associated with left atrial enlargement which is defined as a rather increased left atrial volume than a solely thickened left atrium. Hence, the observed contribution of left atrial wall thickness changes to PTF-V1 might explain the poor empirical correlation of left atrial enlargement with PTF-V1.

scholarly journals Atrial wall thickening, fevers, and atrial fibrillation caused by immunoglobulin G4-related biatrial cardiomyopathy

2020 ◽  
Vol 41 (36) ◽  
pp. 3488-3488
Author(s):  
Tomoyuki Fukuma ◽  
Naoki Fujimoto ◽  
Masaki Ishiyama ◽  
Kaoru Dohi
Keyword(s):  
Atrial Fibrillation ◽  
Wall Thickening ◽  
Atrial Wall ◽  
Immunoglobulin G4

scholarly journals Isolated caecal necrosis—a case study

2019 ◽  
Vol 5 (2) ◽  
pp. 20180089
Author(s):  
Nathan Howard Ho Leung Chan ◽  
Hameed Rafiee ◽  
Ian L P Beales ◽  
Ravindran Karthigan ◽  
Annabel Ciorra ◽  
...  
Keyword(s):  
Iliac Fossa ◽  
Wall Thickening ◽  
Histopathological Analysis ◽  
Ischaemic Colitis ◽  
Rare Presentation ◽  
Bowel Ischaemia ◽  
Right Iliac Fossa Pain ◽  
Bowel Wall Thickening ◽  
The Right

A patient with right iliac fossa pain underwent CT angiography which demonstrated isolated caecal necrosis with associated superior mesenteric artery (SMA) stenosis. This was supported by colonoscopic findings and histopathological analysis. Isolated caecal necrosis is a rare presentation of ischaemic colitis.. Clinical and imaging findings of ischaemic colitis may mimic other pathologies. To improve diagnostic accuracy both referrers and radiologists should be aware of risk factors associated with ischaemic colitis. Isolated bowel wall thickening and pneumatosis of a colonic segment on CT are suggestive of focal bowel ischaemia, in the right clinical context.

scholarly journals Consumption impacts by marine mammals, fish, and seabirds on the Gulf of Maine–Georges Bank Atlantic herring (Clupea harengus) complex during the years 1977–2002

2006 ◽  
Vol 64 (1) ◽  
pp. 83-96 ◽  
Author(s):  
W. J. Overholtz ◽  
J. S. Link
Keyword(s):  
Marine Mammals ◽  
Diet Composition ◽  
Gulf Of Maine ◽  
Demersal Fish ◽  
Pelagic Fish ◽  
Clupea Harengus ◽  
Sensitivity Analyses ◽  
Atlantic Herring ◽  
Georges Bank ◽  
The Impact

Abstract Overholtz, W. J. and Link, J. S. 2007. Consumption impacts by marine mammals, fish, and seabirds on the Gulf of Maine–Georges Bank Atlantic herring (Clupea harengus) complex during the years 1977–2002. ICES Journal of Marine Science, 64: 83–96. A comprehensive study of the impact of predation during the years 1977–2002 on the Gulf of Maine–Georges Bank herring complex is presented. An uncertainty approach was used to model input variables such as predator stock size, daily ration, and diet composition. Statistical distributions were constructed on the basis of available data, producing informative and uninformative inputs for estimating herring consumption within an uncertainty framework. Consumption of herring by predators tracked herring abundance closely during the study period, as this important prey species recovered following an almost complete collapse during the late 1960s and 1970s. Annual consumption of Atlantic herring by four groups of predators, demersal fish, marine mammals, large pelagic fish, and seabirds, averaged just 58 000 t in the late 1970s, increased to 123 000 t between 1986 and 1989, 290 000 t between 1990 and 1994, and 310 000 t during the years 1998–2002. Demersal fish consumed the largest proportion of this total, followed by marine mammals, large pelagic fish, and seabirds. Sensitivity analyses suggest that future emphasis should be placed on collecting time-series of diet composition data for marine mammals, large pelagic fish, and seabirds, with additional monitoring focused on the abundance of seabirds and daily rations of all groups.

Sign in / Sign up

Export Citation Format

Share Document