scholarly journals Numerical Simulation of Enhanced Photoacoustic Generation and Wavefront Shaping by a Distributed Laser Array

2021 ◽  
Vol 11 (20) ◽  
pp. 9497
Author(s):  
Ruijie Hou ◽  
Bin Xu ◽  
Zhiying Xia ◽  
Yang Zhang ◽  
Weiping Liu ◽  
...  
Keyword(s):  
Acoustic Waves ◽  
Photoacoustic Imaging ◽  
Signal To Noise Ratio ◽  
Beam Steering ◽  
Laser Pulses ◽  
Laser Array ◽  
Flexible Control ◽  
Mechanical Waves ◽  
Laser Induced Damage ◽  
Array Generation

In photoacoustic imaging, the use of arrayed laser sources brings several advantages. Acoustic waves can be generated with flexible control of wavefronts, bringing functionality such as ultrasonic beam steering and focusing. The use of arrays reduces the optical intensity while increasing the strength of the ultrasonic wave, bringing the advantages of improved signal-to-noise ratio (SNR) while avoiding laser-induced damage. In this paper, we report a numerical model for studying the generation and shaping of acoustic wavefronts with laser arrays. The propagation of mechanical waves, photoacoustically generated by thermal expansion, is simulated and discussed in detail. In addition, a partially delayed distributed array is studied both theoretically and quantitatively. The developed model for wavefront control through time-delayed laser pulses is shown to be highly suited for the optimization of laser array generation schemes.

scholarly journals Resolution Limits in Photoacoustic Imaging Caused by Acoustic Attenuation

2019 ◽  
Vol 5 (1) ◽  
pp. 13 ◽  
Author(s):  
Peter Burgholzer ◽  
Johannes Bauer-Marschallinger ◽  
Bernhard Reitinger ◽  
Thomas Berer
Keyword(s):  
Acoustic Waves ◽  
Photoacoustic Imaging ◽  
Signal To Noise Ratio ◽  
Finite Size ◽  
Photoacoustic Signal ◽  
Dissipated Energy ◽  
Reconstruction Method ◽  
Square Root ◽  
Resolution Limit ◽  
Acoustic Attenuation

In conventional photoacoustic tomography, several effects contribute to the loss of resolution, such as the limited bandwidth and the finite size of the transducer, or the space-dependent speed of sound. They can all be compensated (in principle) technically or numerically. Frequency-dependent acoustic attenuation also limits spatial resolution by reducing the bandwidth of the photoacoustic signal, which can be numerically compensated only up to a theoretical limit given by thermodynamics. The entropy production, which is the dissipated energy of the acoustic wave divided by the temperature, turns out to be equal to the information loss, which cannot be compensated for by any reconstruction method. This is demonstrated for the propagation of planar acoustic waves in water, which are induced by short laser pulses and measured by piezoelectric acoustical transducers. It turns out that for water, where the acoustic attenuation is proportional to the squared frequency, the resolution limit is proportional to the square root of the distance and inversely proportional to the square root of the logarithm of the signal-to-noise ratio. The proposed method could be used in future work for media other than water, such as biological tissue, where acoustic attenuation has a different power-law frequency dependence.

scholarly journals Photoacoustic Tomography with a Ring Ultrasound Transducer: A Comparison of Different Illumination Strategies

2019 ◽  
Vol 9 (15) ◽  
pp. 3094 ◽  
Author(s):  
Naser Alijabbari ◽  
Suhail S. Alshahrani ◽  
Alexander Pattyn ◽  
Mohammad Mehrmohammadi
Keyword(s):  
Point Source ◽  
Cross Section ◽  
Acoustic Waves ◽  
Signal To Noise Ratio ◽  
Laser Pulses ◽  
Point Of Entry ◽  
Main Challenge ◽  
Optimum Position ◽  
Short Laser Pulses ◽  
Pat System

Photoacoustic (PA) imaging is a methodology that uses the absorption of short laser pulses by endogenous or exogenous chromophores within human tissue, and the subsequent generation of acoustic waves acquired by an ultrasound (US) transducer, to form an image that can provide functional and molecular information. Amongst the various types of PA imaging, PA tomography (PAT) has been proposed for imaging pathologies such as breast cancer. However, the main challenge for PAT imaging is the deliverance of sufficient light energy horizontally through an imaging cross-section as well as vertically. In this study, three different illumination methods are compared for a full-ring ultrasound (US) PAT system. The three distinct illumination setups are full-ring, diffused-beam, and point source illumination. The full-ring system utilizes a cone mirror and parabolic reflector to create the ringed-shaped beam for PAT, while the diffuse scheme uses a light diffuser to expand the beam, which illuminates tissue-mimicking phantoms. The results indicate that the full-ring illumination is capable of providing a more uniform fluence irrespective of the vertical depth of the imaged cross-section, while the point source and diffused illumination methods provide a higher fluence at regions closer to the point of entry, which diminishes with depth. In addition, a set of experiments was conducted to determine the optimum position of ring-illumination with respect to the position of the acoustic detectors to achieve the highest signal-to-noise ratio.

scholarly journals High laser induced damage threshold photoresists for nano-imprint and 3D multi-photon lithography

Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Elmina Kabouraki ◽  
Vasileia Melissinaki ◽  
Amit Yadav ◽  
Andrius Melninkaitis ◽  
Konstantina Tourlouki ◽  
...  
Keyword(s):  
Nanoimprint Lithography ◽  
Three Dimensional ◽  
Damage Threshold ◽  
Laser Pulses ◽  
Intense Laser ◽  
Optical Elements ◽  
Photonic Circuits ◽  
Future Production ◽  
Intense Laser Pulses ◽  
Laser Induced Damage

Abstract Optics manufacturing technology is predicted to play a major role in the future production of integrated photonic circuits. One of the major drawbacks in the realization of photonic circuits is the damage of optical materials by intense laser pulses. Here, we report on the preparation of a series of organic–inorganic hybrid photoresists that exhibit enhanced laser-induced damage threshold. These photoresists showed to be candidates for the fabrication of micro-optical elements (MOEs) using three-dimensional multiphoton lithography. Moreover, they demonstrate pattern ability by nanoimprint lithography, making them suitable for future mass production of MOEs.

scholarly journals Laser-induced damage thresholds of ultrathin targets and their constraint on laser contrast in laser-driven ion acceleration experiments

2020 ◽  
Vol 8 ◽  
Author(s):  
Dahui Wang ◽  
Yinren Shou ◽  
Pengjie Wang ◽  
Jianbo Liu ◽  
Zhusong Mei ◽  
...  
Keyword(s):  
Damage Threshold ◽  
Wide Band ◽  
Laser Pulses ◽  
Laser Damage Threshold ◽  
Single Shot ◽  
Bulk Materials ◽  
Free Standing ◽  
Wide Band Gap ◽  
Different Types ◽  
Laser Induced Damage

Abstract Single-shot laser-induced damage threshold (LIDT) measurements of multi-type free-standing ultrathin foils were performed in a vacuum environment for 800 nm laser pulses with durations τ ranging from 50 fs to 200 ps. The results show that the laser damage threshold fluences (DTFs) of the ultrathin foils are significantly lower than those of corresponding bulk materials. Wide band gap dielectric targets such as SiN and formvar have larger DTFs than semiconductive and conductive targets by 1–3 orders of magnitude depending on the pulse duration. The damage mechanisms for different types of targets are studied. Based on the measurement, the constrain of the LIDTs on the laser contrast is discussed.

Ultrasmall hybrid protein–copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with a high signal-to-noise ratio

2019 ◽  
Vol 7 (1) ◽  
pp. 92-103 ◽  
Author(s):  
Huixiang Yan ◽  
Jingqin Chen ◽  
Ying Li ◽  
Yuanyuan Bai ◽  
Yunzhu Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Copper Sulfide ◽  
Photoacoustic Imaging ◽  
Signal To Noise Ratio ◽  
Nanoparticle Synthesis ◽  
High Signal ◽  
Hybrid Protein ◽  
Signal To Noise ◽  
Noise Ratio

A schematic illustration of CuS@BSA-RGD nanoparticle synthesis and the application of photoacoustic imaging in an orthotopic HCC model.

Generation of surface acoustic waves in silicon with energetic femtosecond laser pulses

2003 ◽  
Vol 74 (1) ◽  
pp. 453-455 ◽  
Author(s):  
Al. A. Kolomenskii ◽  
S. N. Jerebtsov ◽  
H. A. Schuessler
Keyword(s):  
Femtosecond Laser ◽  
Acoustic Waves ◽  
Surface Acoustic Waves ◽  
Laser Pulses ◽  
Femtosecond Laser Pulses

scholarly journals LASER-INDUCED SURFACE ACOUSTIC WAVES FOR THIN FILM CHARACTERIZATION

2020 ◽  
Vol 27 ◽  
pp. 57-61
Author(s):  
Radim Kudělka ◽  
Lukáš Václavek ◽  
Jan Tomáštík ◽  
Sabina Malecová ◽  
Radim Čtvrtlík
Keyword(s):  
Thin Films ◽  
Film Thickness ◽  
Young’S Modulus ◽  
Acoustic Waves ◽  
Young's Modulus ◽  
Surface Acoustic Waves ◽  
Laser Pulses ◽  
Data Application ◽  
Thin Film Characterization ◽  
Short Laser Pulses

Knowledge of mechanical properties of thin films is essential for most of their applications. However, their determination can be problematic for very thin films. LAW (Laser-induced acoustic waves) is a combined acousto-optic method capable of measuring films with thickness from few nanometers. It utilizes ultrasound surface waves which are excited via short laser pulses and detected by a PVDF foil. Properties such as Young’s modulus, Poisson’s ratio and density of both the film and the substrate as well as film thickness can be explored.Results from the LAW method are successfully compared with nanoindentation for Young’s modulus evaluation and with optical method for film thickness evaluation and also with literature data. Application of LAW for anisotropy mapping of materials with cubic crystallographic lattice is also demonstrated.

scholarly journals Photoacoustic Imaging with Capacitive Micromachined Ultrasound Transducers: Principles and Developments

Sensors ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 3617 ◽  
Author(s):  
Jasmine Chan ◽  
Zhou Zheng ◽  
Kevan Bell ◽  
Martin Le ◽  
Parsin Haji Reza ◽  
...  
Keyword(s):  
Photoacoustic Imaging ◽  
Signal To Noise Ratio ◽  
Complementary Metal Oxide Semiconductor ◽  
Photoacoustic Signal ◽  
Motion Artifacts ◽  
Oxide Semiconductor ◽  
Ring Resonators ◽  
Ultrasound Transducers ◽  
Fabrication Technique ◽  
Acoustic Techniques

Photoacoustic imaging (PAI) is an emerging imaging technique that bridges the gap between pure optical and acoustic techniques to provide images with optical contrast at the acoustic penetration depth. The two key components that have allowed PAI to attain high-resolution images at deeper penetration depths are the photoacoustic signal generator, which is typically implemented as a pulsed laser and the detector to receive the generated acoustic signals. Many types of acoustic sensors have been explored as a detector for the PAI including Fabry–Perot interferometers (FPIs), micro ring resonators (MRRs), piezoelectric transducers, and capacitive micromachined ultrasound transducers (CMUTs). The fabrication technique of CMUTs has given it an edge over the other detectors. First, CMUTs can be easily fabricated into given shapes and sizes to fit the design specifications. Moreover, they can be made into an array to increase the imaging speed and reduce motion artifacts. With a fabrication technique that is similar to complementary metal-oxide-semiconductor (CMOS), CMUTs can be integrated with electronics to reduce the parasitic capacitance and improve the signal to noise ratio. The numerous benefits of CMUTs have enticed researchers to develop it for various PAI purposes such as photoacoustic computed tomography (PACT) and photoacoustic endoscopy applications. For PACT applications, the main areas of research are in designing two-dimensional array, transparent, and multi-frequency CMUTs. Moving from the table top approach to endoscopes, some of the different configurations that are being investigated are phased and ring arrays. In this paper, an overview of the development of CMUTs for PAI is presented.

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