scholarly journals Bioengineering Progress in Lung Assist Devices

2021 ◽  
Vol 8 (7) ◽  
pp. 89
Author(s):  
Ahad Syed ◽  
Sarah Kerdi ◽  
Adnan Qamar
Keyword(s):  
Lung Function ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Historical Development ◽  
Artificial Lung ◽  
Current State ◽  
Native Lung ◽  
Injured Lung ◽  
Artificial Lungs ◽  
State Of Affairs

Artificial lung technology is advancing at a startling rate raising hopes that it would better serve the needs of those requiring respiratory support. Whether to assist the healing of an injured lung, support patients to lung transplantation, or to entirely replace native lung function, safe and effective artificial lungs are sought. After 200 years of bioengineering progress, artificial lungs are closer than ever before to meet this demand which has risen exponentially due to the COVID-19 crisis. In this review, the critical advances in the historical development of artificial lungs are detailed. The current state of affairs regarding extracorporeal membrane oxygenation, intravascular lung assists, pump-less extracorporeal lung assists, total artificial lungs, and microfluidic oxygenators are outlined.

scholarly journals Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure

Membranes ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 225
Author(s):  
Barbara Ficial ◽  
Francesco Vasques ◽  
Joe Zhang ◽  
Stephen Whebell ◽  
Michael Slattery ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Respiratory Failure ◽  
Lung Function ◽  
Gas Exchange ◽  
Extracorporeal Membrane Oxygenation ◽  
Life Support ◽  
Co2 Removal ◽  
Physiological Basis ◽  
Membrane Oxygenation ◽  
Native Lung

Extracorporeal life support (ECLS) for severe respiratory failure has seen an exponential growth in recent years. Extracorporeal membrane oxygenation (ECMO) and extracorporeal CO2 removal (ECCO2R) represent two modalities that can provide full or partial support of the native lung function, when mechanical ventilation is either unable to achieve sufficient gas exchange to meet metabolic demands, or when its intensity is considered injurious. While the use of ECMO has defined indications in clinical practice, ECCO2R remains a promising technique, whose safety and efficacy are still being investigated. Understanding the physiological principles of gas exchange during respiratory ECLS and the interactions with native gas exchange and haemodynamics are essential for the safe applications of these techniques in clinical practice. In this review, we will present the physiological basis of gas exchange in ECMO and ECCO2R, and the implications of their interaction with native lung function. We will also discuss the rationale for their use in clinical practice, their current advances, and future directions.

POST-COSMISM AND POST-HUMANISM: TWO STRATEGIES IN THE MOD-ERN PHILOSOPHY OF THE HUMAN

Chelovek RU ◽  
2020 ◽  
pp. 217-220
Author(s):  
Natalia Rostova ◽  
Keyword(s):  
Human Exceptionalism ◽  
Current State ◽  
Human World ◽  
State Of Affairs ◽  
Post Humanism

The article analyzes the current state of affairs in philosophy in relation to the question «What is hu-man?». In this regard, the author identifies two strategies – post-humanism and post-cosmism. The strat-egy of post-humanism is to deny the idea of human exceptionalism. Humanity becomes something that can be thought of out of touch with human and understood as a right that extends to the non-human world. Post-cosmism, on the contrary, advocated the idea of ontological otherness of the human. Re-sponding to the challenges of anthropological catastrophe, its representatives propose a number of new anthropological projects.

Critical Thinking and Its Implications for Contemporary Ijtihad

2010 ◽  
Vol 27 (4) ◽  
pp. 45-67
Author(s):  
Sayed Sikandar Shah ◽  
Mek Wok Mahmud
Keyword(s):  
Critical Thinking ◽  
Legal Theory ◽  
Dynamic Feature ◽  
Islamic Revival ◽  
Current State ◽  
Islamic Legal Theory ◽  
Islamic Jurisprudence ◽  
Revival Movements ◽  
State Of Affairs ◽  
Islamic Civilization

As an intellectual process, critical thinking plays a dynamic role in reconstructing human thought. In Islamic legal thought, this intellectual tool was pivotal in building a full-fledged jurisprudential system during the golden age of Islamic civilization. With the solidification of the science of Islamic legal theory and the entrenchment of classical Islamic jurisprudence, this process abated somewhat. Recent Islamic revival movements have engendered a great zeal for reinstituting this process. The current state of affairs in constructing and reconstructing Islamic jurisprudence by and large do not, however, reflect the dynamic feature of intellectual thought in this particular discipline. Thus this article attempts to briefly delineate this concept, unveil the reality on the ground, and identify some hands-on strategies for applying critical thinking in contemporary ijtihad.

The Al-Qaeda Revival in Pakistan: Challenges and Prospects

1970 ◽  
Author(s):  
Farhan Zahid
Keyword(s):  
Law Enforcement ◽  
Terrorist Group ◽  
Al Qaeda ◽  
Vital Importance ◽  
High Profile ◽  
Current State ◽  
The Us ◽  
Terrorist Organization ◽  
State Of Affairs ◽  
Tribal Areas

Pakistan remains a country of vital importance for Al-Qaeda. It is primarily because of Al-Qaeda’s advent, rise and shelter and not to mention the support the terrorist organization found at the landscape of Pakistan during the last two decades. The emergence of in Pakistan can be traced back to the Afghan War (1979-89), with a brief sabbatical in Sudan the Islamist terrorist group rose to gain prominence after shifting back to Afghanistan. It then became a global ‘Islamist’ terrorist entity while based in neighboring Afghanistan and found safe havens in the erstwhile tribal areas of Pakistan in the aftermath of the US invasion of Afghanistan in 2001. Prior to its formation in 1988 in Peshawar (Pakistan), it had worked as Maktab al-Khidmat (Services Bureau) during the Afghan War.2 It had its roots in Pakistan, which had become a transit point of extremists en route to Afghanistan during the War. All high profile Al-Qaeda leaders, later becoming high-value targets, and members of its central Shura had lived in Pakistan at one point in their lives. That is the very reason the Al-Qaeda in Pakistan is termed as Al-Qaeda Core or Central among law enforcement practitioners and intelligence communities. Without going into details of Al-Qaeda’s past in Pakistan the aim of this article is to focus on its current state of affairs and what future lies ahead of it in Pakistan.

scholarly journals Ice-Breaking Fleets of the United States and Canada: Assessing the Current State of Affairs and Future Plans

2021 ◽  
Vol 13 (2) ◽  
pp. 703
Author(s):  
Megan Drewniak ◽  
Dimitrios Dalaklis ◽  
Anastasia Christodoulou ◽  
Rebecca Sheehan
Keyword(s):  
United States ◽  
The United States ◽  
Maritime Transportation ◽  
The Arctic ◽  
Polar Ice ◽  
Northwest Passage ◽  
Ice Cap ◽  
Ice Coverage ◽  
Current State ◽  
State Of Affairs

In recent years, a continuous decline of ice-coverage in the Arctic has been recorded, but these high latitudes are still dominated by earth’s polar ice cap. Therefore, safe and sustainable shipping operations in this still frozen region have as a precondition the availability of ice-breaking support. The analysis in hand provides an assessment of the United States’ and Canada’s polar ice-breaking program with the purpose of examining to what extent these countries’ relevant resources are able to meet the facilitated growth of industrial interests in the High North. This assessment will specifically focus on the maritime transportation sector along the Northwest Passage and consists of four main sections. The first provides a very brief description of the main Arctic passages. The second section specifically explores the current situation of the Northwest Passage, including the relevant navigational challenges, lack of infrastructure, available routes that may be used for transit, potential choke points, and current state of vessel activity along these routes. The third one examines the economic viability of the Northwest Passage compared to that of the Panama Canal; the fourth and final section is investigating the current and future capabilities of the United States’ and Canada’s ice-breaking fleet. Unfortunately, both countries were found to be lacking the necessary assets with ice-breaking capabilities and will need to accelerate their efforts in order to effectively respond to the growing needs of the Arctic. The total number of available ice-breaking assets is impacting negatively the level of support by the marine transportation system of both the United States and Canada; these two countries are facing the possibility to be unable to effectively meet the expected future needs because of the lengthy acquisition and production process required for new ice-breaking fleets.

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