scholarly journals Inhibitory Performance in Smokers Relative to Nonsmokers When Exposed to Neutral, Smoking- and Money-Related Pictures

2021 ◽  
Vol 11 (10) ◽  
pp. 128
Author(s):  
Afework Tsegaye ◽  
Cuiling Guo ◽  
Renáta Cserjési ◽  
Leon Kenemans ◽  
Gijsbert Stoet ◽  
...  
Keyword(s):  
Inhibitory Control ◽  
Nicotine Addiction ◽  
Health Consequences ◽  
Exact Role ◽  
Approach Bias ◽  
Neutral Context ◽  
Incentive Sensitization

Introduction: Smoking is associated with significant negative health consequences. It has been suggested that deficient inhibitory control may be implicated in (nicotine) addiction, but its exact role has not yet been elucidated. In the current study, our aim was to investigate the role of inhibitory control in relation to nicotine addiction in contexts that differ in terms of reward. Methods: Participants filled out questionnaires and performed a go/no-go task with three conditions. In one condition, the stimuli were neutral color squares, and in the reward conditions, these were smoking-related pictures and money-related pictures, respectively. In total, 43 non-abstinent individuals that smoke and 35 individuals that do not smoke were included in the sample. Results: The main results showed that individuals that smoke, relative to individuals that do not smoke, had reduced inhibitory control in both reward contexts, relative to a neutral context. The reductions in inhibitory control were mirrored by speeded responses. Conclusions: Individuals that smoke seem to present with reduced inhibitory control, which is most pronounced in contexts of reward. Consistent with incentive sensitization theory, the reduced inhibitory control may be (at least partly) due to the heightened approach bias to reward-related stimuli as indicated by the speeded responses.

scholarly journals The Enigma of Eosinophil Degranulation

2021 ◽  
Vol 22 (13) ◽  
pp. 7091
Author(s):  
Timothée Fettrelet ◽  
Lea Gigon ◽  
Alexander Karaulov ◽  
Shida Yousefi ◽  
Hans-Uwe Simon
Keyword(s):  
Blood Cells ◽  
Inflammatory Diseases ◽  
White Blood Cells ◽  
Exact Role ◽  
Effector Cells ◽  
Effector Functions ◽  
Cytotoxic Effector ◽  
Eosinophil Degranulation

Eosinophils are specialized white blood cells, which are involved in the pathology of diverse allergic and nonallergic inflammatory diseases. Eosinophils are traditionally known as cytotoxic effector cells but have been suggested to additionally play a role in immunomodulation and maintenance of homeostasis. The exact role of these granule-containing leukocytes in health and diseases is still a matter of debate. Degranulation is one of the key effector functions of eosinophils in response to diverse stimuli. The different degranulation patterns occurring in eosinophils (piecemeal degranulation, exocytosis and cytolysis) have been extensively studied in the last few years. However, the exact mechanism of the diverse degranulation types remains unknown and is still under investigation. In this review, we focus on recent findings and highlight the diversity of stimulation and methods used to evaluate eosinophil degranulation.

scholarly journals Inhibitory control mediates the interaction between serotonin transporter gene (5-HTTLPR) and peer victimization on adolescent depressive symptoms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaonan Lin ◽  
Yanmiao Cao ◽  
Linqin Ji ◽  
Wenxin Zhang
Keyword(s):  
Depressive Symptoms ◽  
Peer Victimization ◽  
Inhibitory Control ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Chinese Han ◽  
Mediating Role ◽  
Adolescent Depressive Symptoms

AbstractMany efforts have been devoted to investigating the effect of the interaction between the serotonin transporter gene (5-HTTLPR) and environment (G × E) on depression, but they yield mixed results. The inconsistency has suggested that G × E effects may be more complex than originally conceptualized, and further study is warranted. This study explored the association among 5-HTTLPR, peer victimization and depressive symptoms and the underlying mediating role of inhibitory control in this association. A total of 871 Chinese Han adolescents (Mage = 15.32 years, 50.3% girls) participated and provided saliva samples from which the 5-HTTLPR was genotyped. This study found that 5-HTTLPR interacted with peer victimization in predicting depressive symptoms. Adolescents carrying L allele reported more depressive symptoms than SS carriers when exposed to higher level of peer victimization. Furthermore, adolescents’ inhibitory control deficits mediated the association between 5-HTTLPR × peer victimization and depressive symptoms. These findings suggested that one pathway in which G × E may confer vulnerability to depressive symptoms is through disruptions to adolescents’ inhibitory control system.

Considering Spirituality in Occupational Therapy Practice

1994 ◽  
Vol 61 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Mary Egan ◽  
M. Denise Delaat
Keyword(s):  
Health Care ◽  
Clinical Practice ◽  
Occupational Therapy ◽  
Occupational Therapists ◽  
Occupational Performance ◽  
Exact Role ◽  
Therapy Guidelines

Despite its prominent place in the Occupational Therapy Guidelines for client-centred practice, the exact role of spirituality in clinical practice has been difficult to delineate. In this paper current concepts of spirituality are outlined and ways in which these concepts have been applied in health care are described. To illustrate these spiritual concepts, the experiences of individuals whom the authors have met in their clinical practice are outlined in a series of vignettes. Finally, a revision of the model of occupational performance which enhances consideration of spirituality in occupational therapy practice is proposed, and some guidelines for occupational therapists wishing to incorporate spiritual concerns in therapy are suggested.

scholarly journals Ancient Pneumatics Transformed during the Early Modern Period

Nuncius ◽  
2014 ◽  
Vol 29 (1) ◽  
pp. 127-173 ◽  
Author(s):  
Matteo Valleriani
Keyword(s):  
Sixteenth Century ◽  
Early Modern ◽  
Early Modern Period ◽  
Logical Structure ◽  
Exact Role ◽  
Ancient Technology ◽  
Ancient Science ◽  
Modern Period ◽  
Natural Philosophers

The paper aims to show how sixteenth century hydraulic and pneumatic engineers appropriated ancient science and technology – codified in the text of Hero of Alexandria’s Pneumatics – to enter into scientific discourse, for instance, with natural philosophers. They drew on the logical structure, content and narrative style passed down from antiquity to generate and codify their own theoretical approach and to document their new technological achievements. They did so by using the form of commented and enlarged editions, just as Aristotelian natural philosophers had been doing for centuries. The argument aims to detail the exact role of ancient science and the process of transformation it underwent during the early modern period. In particular, it aims to show how pneumatic engineers first tested the ancient technology codified by Hero while carrying out their own practical activities. Once these tests were successfully concluded, in the spirit of early modern humanism they finally presented these activities as being associated with the work of their discipline’s most authoritative author, Hero of Alexandria, whose technology was tested during the construction of the hydraulic and pneumatic system of the garden of Pratolino.

The role of iron in the preparation and oxygen reduction reaction activity of nitrogen-doped carbon

2015 ◽  
Vol 51 (12) ◽  
pp. 2450-2453 ◽  
Author(s):  
Dae-Soo Yang ◽  
Min Young Song ◽  
Kiran Pal Singh ◽  
Jong-Sung Yu
Keyword(s):  
Oxygen Reduction Reaction ◽  
Oxygen Reduction ◽  
Carbon Sources ◽  
Reduction Reaction ◽  
Acidic Media ◽  
Oxygen Reduction Reaction Activity ◽  
Exact Role ◽  
Ordered Mesoporous ◽  
Nitrogen Doped Carbon

The exact role of iron in catalyzing oxygen reduction reaction in both alkaline and acidic media is portrayed with unique platelet ordered mesoporous carbon prepared using Fe-phthalocyanine as iron, nitrogen and carbon sources.

scholarly journals Role of viruses in oral squamous cell carcinoma

2012 ◽  
Vol 6 (2) ◽  
pp. 21 ◽  
Author(s):  
Rashmi Metgud ◽  
Madhusudan Astekar ◽  
Meenal Verma ◽  
Ashish Sharma
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Genetic Susceptibility ◽  
Squamous Cell ◽  
Oncogenic Viruses ◽  
Exact Role ◽  
Carcinogenic Effects

The etiology of oral squamous cell carcinoma (OSCC) is complex and involves many factors. The most clearly defined risk factors are smoking and alcohol, which substantially increase the risk of oral SCC. However, despite this clear association, a substantial proportion of patients develop OSCC without exposure to them, emphasizing the role of other risk factors such as genetic susceptibility and oncogenic viruses. Some viruses are strongly associated with OSCC while the association of others is less frequent and may depend on co-factors for their carcinogenic effects. Therefore, the exact role of viruses must be evaluated with care in order to improve the diagnosis and treatment of OSCC.

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