scholarly journals Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy

Cancers ◽  
2011 ◽  
Vol 3 (3) ◽  
pp. 2827-2843 ◽  
Author(s):  
Janina Seznec ◽  
Ulrike Naumann
Keyword(s):  
Cell Death ◽  
Signaling Pathways ◽  
Cell Line ◽  
Microarray Analysis ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
Novel Genes ◽  
A Cell

Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line

2008 ◽  
Vol 27 (5) ◽  
pp. 440-446 ◽  
Author(s):  
Mario Luiz Conte da Frota ◽  
Elizandra Braganhol ◽  
Andrés Delgado Canedo ◽  
Fabio Klamt ◽  
Miriam Anders Apel ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Marine Sponge ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
Caspase 9 ◽  
Apoptotic Pathway ◽  
Polymastia Janeirensis

scholarly journals Troglitazone Reduces Glyoxalase I Protein Expression in Glioma and Potentiates the Effects of Chemotherapeutic Agents

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Jeffrey Helgager ◽  
Jie Li ◽  
Irina A. Lubensky ◽  
Russell Lonser ◽  
Zhengping Zhuang
Keyword(s):  
Cell Death ◽  
Enzyme Activity ◽  
Protein Expression ◽  
Cell Line ◽  
Glioma Cell ◽  
Chemotherapeutic Agents ◽  
Glioma Cell Line ◽  
Glyoxalase I ◽  
Chromosome 1P ◽  
In Cells

Despite resistance of most gliomas to chemotherapy, approximately 2/3 of oligodendrogliomas show sensitivity to such agents. This sensitivity has been associated with deletions on chromosome 1p alone or in combination with 19q. Higher expression of the enzyme glyoxalase I has been found in oligodendrogliomas with chromosome 1p intact compared to those with a deletion. Higher expression of this enzyme is also associated with tumor chemoresistance in other cancers. The present study tested whether the drug troglitazone would make a glioma cell line more sensitive to chemotherapeutic agents. This drug was chosen because it has been shown to decrease glyoxalase I enzyme activity in cells. Treatment with troglitazone decreased expression of glyoxalase I, and potentiated cell death when used in combination with chemotherapeutic agents. This decrease in glyoxalase I protein may be one mechanism by which this potentiation occurs, and troglitazone may be a candidate for use in glioma therapy.

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

2008 ◽  
Vol 27 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Mario Luiz Conte da Frota ◽  
Elizandra Braganhol ◽  
Andrés Delgado Canedo ◽  
Fabio Klamt ◽  
Miriam Anders Apel ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cell Death ◽  
Cell Line ◽  
Marine Sponge ◽  
Normal Cell ◽  
Glioma Cell ◽  
Apoptotic Cell ◽  
Glioma Cell Line ◽  
Apoptotic Cell Death ◽  
Polymastia Janeirensis

scholarly journals P2X7 receptor activation leads to increased cell death in a radiosensitive human glioma cell line

2012 ◽  
Vol 8 (4) ◽  
pp. 729-739 ◽  
Author(s):  
Marina Petersen Gehring ◽  
Talita Carneiro Brandão Pereira ◽  
Rafael Fernandes Zanin ◽  
Magali Carvalho Borges ◽  
Aroldo Braga Filho ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
P2x7 Receptor ◽  
Glioma Cell ◽  
Receptor Activation ◽  
Glioma Cell Line ◽  
Human Glioma ◽  
Human Glioma Cell Line ◽  
Human Glioma Cell ◽  
P2x7 Receptor Activation

Increased Bax Expression Is Associated with Cell Death Induced by Ganciclovir in a Herpes Thymidine Kinase Gene-Expressing Glioma Cell Line

1999 ◽  
Vol 10 (4) ◽  
pp. 679-688 ◽  
Author(s):  
D. Craperi ◽  
J.-M. Vicat ◽  
M.-F. Nissou ◽  
J. Mathieu ◽  
J. Baudier ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Thymidine Kinase ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
Thymidine Kinase Gene ◽  
Kinase Gene ◽  
Gene Expressing

Photochemical internalization of bleomycin and temozolomide – in vitro studies on the glioma cell line F98

2015 ◽  
Vol 14 (7) ◽  
pp. 1357-1366 ◽  
Author(s):  
Odrun A. Gederaas ◽  
Anette Hauge ◽  
Pål G. Ellingsen ◽  
Kristian Berg ◽  
Dag Altin ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Glioma Cell ◽  
Cell Model ◽  
Glioma Cell Line ◽  
In Vitro Studies ◽  
Photochemical Internalization ◽  
F98 Glioma

Photochemical internalization and illumination together with chemotherapeutics result in synergetic cell death in the F98 glioma cell model.

Effect of Proline on Cell Death, Cell Cycle, and Oxidative Stress in C6 Glioma Cell Line

2020 ◽  
Author(s):  
Andréa Gisiane Kurek Ferreira ◽  
Helena Biasibetti-Brendler ◽  
Daniele Susana Volkart Sidegum ◽  
Samanta Oliveira Loureiro ◽  
Fabrício Figueiró ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Cycle ◽  
Cell Death ◽  
Cell Line ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
C6 Glioma ◽  
C6 Glioma Cell ◽  
And Oxidative Stress

Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysis

2007 ◽  
Vol 30 (3) ◽  
pp. 181-187 ◽  
Author(s):  
Brian T. Ragel ◽  
William T. Couldwell ◽  
David L. Gillespie ◽  
Randy L. Jensen
Keyword(s):  
Malignant Glioma ◽  
Cell Line ◽  
Microarray Analysis ◽  
Cdna Microarray ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
Cdna Microarray Analysis ◽  
Induced Genes
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