scholarly journals Clinical Features, Histopathology and Differential Diagnosis of Sarcoidosis

Cells ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 59
Author(s):  
Claudio Tana ◽  
Iginio Donatiello ◽  
Alessandro Caputo ◽  
Marco Tana ◽  
Teresa Naccarelli ◽  
...  

Sarcoidosis is a chameleon disease of unknown etiology, characterized by the growth of non-necrotizing and non-caseating granulomas and manifesting with clinical pictures that vary on the basis of the organs that are mainly affected. Lungs and intrathoracic lymph nodes are the sites that are most often involved, but virtually no organ is spared from this disease. Histopathology is distinctive but not pathognomonic, since the findings can be found also in other granulomatous disorders. The knowledge of these findings is important because it could be helpful to differentiate sarcoidosis from the other granulomatous-related diseases. This review aims at illustrating the main clinical and histopathological findings that could help clinicians in their routine clinical practice.

2000 ◽  
Vol 5 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Allan S Gordon

Practitioners are often presented with patients who complain bitterly of facial pain. The trigeminal nerve is involved in four conditions that are sometimes mixed up. The four conditions - trigeminal neuralgia, trigeminal neuropathic pain, postherpetic neuralgia and atypical facial pain - are discussed under the headings of clinical features, differential diagnosis, cause and treatment. This article should help practitioners to differentiate one from the other and to manage their care.


2020 ◽  
Vol 8 (9) ◽  
pp. 4324-4328
Author(s):  
Karthika Raj ◽  
Susheel Shetty

Pandu is a Pitta Pradhana Tridoshaja Vikara affecting the Rasavaha srotas causing Sapta Dhatu Kshaya and Ojokshaya1. The disease is characterized by Panduvamata and Arohana Ayasa. Karnakshweda, Agnimandya, Daurbalya, Annadwesha, Srama, Bhrama, Gathrashoola, Arohanaayasa, Aruchi, Gaurava etc. are the other symptoms commonly found in the patients of Pandu. In the Present era, Anaemia is a burning issue around the world and W.H.O Global data base 2011 reveals that, in a 120 million population, 83% people are suffering from anaemia2.Present study was conducted on 60 diagnosed patients of Panduwho were randomly allocated with 30 each in two groups. Darvyadhi Lehya was given for one group and Drakshadhi Lehya a widely used formulation in clinical practice was given for another group. The study was conducted in 60 subjects for a period of 30 days. Clinical features and haematological parameters were documented before and after the treatment. The results of the study showed that, a statistically significant difference was not seen between the effect of Darvyadi and Drakshadilehya in Pandu roga.


2007 ◽  
Vol 97 (5) ◽  
pp. 415-419 ◽  
Author(s):  
Pedro Carpintero ◽  
Emilio Gascon ◽  
Manuel Mesa ◽  
Carlos Jimenez ◽  
Ubaldo Lopez

Pigmented villonodular synovitis, a rare proliferative disease of unknown etiology, is rare in the foot (2% of these lesions). A retrospective review was undertaken of the case histories, radiographs, and imaging results of eight patients treated for pigmented villonodular synovitis of the foot. Pigmented villonodular synovitis was located in the rearfoot in five patients and in the forefoot in the other three. Radiographs in six patients showed bone involvement. Affected bones included the talus, first cuneiform, first and fifth metatarsals, and second phalanx. Treatment was surgical, and only one recurrence was recorded after 24 months. Pigmented villonodular synovitis should be considered in the differential diagnosis of foot tumors. (J Am Podiatr Med Assoc 97(5): 415–419, 2007)


2019 ◽  
pp. 175-180
Author(s):  
Matthew J. Thurtell ◽  
Robert L. Tomsak

Upper-eyelid ptosis is frequently encountered in clinical practice but has a broad differential diagnosis. It can produce visual symptoms when the pupil is encroached by the upper eyelid. In this chapter, we begin by reviewing the clinical features that help with localization of the lesion responsible for upper-eyelid ptosis. We next describe the components of the eyelid examination that help to quantify and characterize upper-eyelid ptosis. We then discuss the features of levator dehiscence and list its common causes, which include involutional changes in orbital connective tissues, long-term use of contact lenses, and iatrogenic trauma. Lastly, we review the treatment options for levator dehiscence.


Author(s):  
Matthew A. Stein

The breast ultrasound (US) finding known as “complex mass” has undergone a labeling revision with the fifth edition of the BI-RADS Atlas and is now designated as complex cystic and solid mass (CCSM). The updated BI-RADS sought to unambiguously define and differentiate an actionable finding often requiring biopsy from a lesser finding requiring, at most, imaging follow-up to confirm expected stability. This chapter, appearing in the section on nipple, skin and lymph nodes, reviews key imaging and clinical features, imaging protocols and pitfalls, differential diagnosis, and clinical recommendations for complex cystic and solid masses. Topics include the rationale for the updated BI-RADS lexicon, the important differentiation of a complex cystic and solid mass from a complicated cyst, and a framework for the differentiation and management of actionable and non-actionable masses with complex cystic and solid features at ultrasound.


Oral Oncology ◽  
2019 ◽  
Vol 92 ◽  
pp. 99-100 ◽  
Author(s):  
Rama Jayaraj ◽  
Chellan Kumarasamy ◽  
Madhav Madurantakam Royam ◽  
Shanthi Sabarimurugan ◽  
Siddhartha Baxi

2018 ◽  
Vol 142 (10) ◽  
pp. 1164-1176 ◽  
Author(s):  
Alexander S. Taylor ◽  
Rohit Mehra ◽  
Aaron M. Udager

Primary glandular tumors of the urachus and urinary bladder are an intriguing group of clinically and morphologically diverse neoplasms for which there have been recent refinements in diagnostic subclassification and advances in molecular pathology. In addition, the urachus and urinary bladder may be secondarily involved by tumors with glandular differentiation that demonstrate remarkable morphologic, immunophenotypic, and molecular overlap. Thus, surgical pathologists need to be aware of the broad differential diagnosis of glandular tumors that involve the urachus and urinary bladder and have a practical diagnostic framework to evaluate these lesions in routine clinical practice. In this review, we summarize the salient clinical, morphologic, immunohistochemical, and molecular features of glandular tumors of the urachus and urinary bladder, including mucinous cystic tumors of the urachus, noncystic urachal adenocarcinomas, urothelial carcinomas with glandular or pseudoglandular features, primary urinary bladder adenocarcinomas, and Müllerian-type carcinomas, highlighting the strengths and limitations of various diagnostic features and ancillary tests, as well as the need for close clinical and radiographic correlation.


2017 ◽  
Vol 74 (9) ◽  
pp. 900-903
Author(s):  
Stevan Mihailovic

Introduction. Capnography is an essential part and standard monitoring tool during the perioperative period, which can be invaluable in detecting anaesthetic equipment malfunction. Case report. The atypical, ??tails-up?? capnographic waveform was noticed during routine surgical operation. Comprehensive physico-mathematical and graphical explanation of this complex capnographic pattern has been given, together with in-depth analysis of possible differential diagnosis and clinical significance for routine clinical practice. Conclusion. ?Tails-up?? capnographic trace gives early clue to diagnosing and fixing the problem of cracks in sampling line, before leading to an inadequate course of action. The understanding of the physics and physiology behind capnography is of vital importance for the analysis of capnographic waveforms, for early detection of anaesthetic equipment malfunction and for safe clinical practice.


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