scholarly journals Research Progress in Corrosion Mechanism of Reinforced Alkali-Activated Concrete Structures

2021 ◽  
Vol 2 (4) ◽  
pp. 641-656
Author(s):  
Feng Zhang ◽  
Xun Xi ◽  
Shangtong Yang
Keyword(s):  
Concrete Structures ◽  
Solution Chemistry ◽  
Research Progress ◽  
Future Research ◽  
Corrosion Mechanism ◽  
Chloride Ingress ◽  
Widespread Application ◽  
Alkali Activated Concrete ◽  
Alkali Activated ◽  
Concrete Interface

In this paper, the recent research progress on the corrosion of reinforced alkali-activated materials (AAMs) concrete structures is reviewed. The corrosion mechanisms induced by carbonation and chloride ingress in AAMs concrete are discussed, from the perspectives of composition, microstructure and pore solution chemistry, in comparison to ordinary Portland cement (OPC) concrete. The steel–alkali-activated concrete interface is a key to investigating corrosion initiation and propagation, which has different physical and chemical characteristics of the steel–concrete interface in OPC concrete. Moreover, the electrochemical process testing methods including half-cell potential and linear polarization resistance are critically discussed with a focus on what could be inherited from the OPC concrete and what criteria are no longer suitable for AAMs concrete due to underestimation in most cases. New data and theories are urgently needed for using AAMs in concrete structures to replace OPC. At the end of this paper, the research gaps and future research needs are summarised for the sake of widespread application of AAMs in concrete structures for sustainable and low-carbon construction.

Study on corrosion mechanism of alkali-activated concrete with biogenic sulfuric acid

2018 ◽  
Vol 188 ◽  
pp. 9-16 ◽  
Author(s):  
Yudong Xie ◽  
Xujian Lin ◽  
Weijie Pan ◽  
Tao Ji ◽  
Yongning Liang ◽  
...  
Keyword(s):  
Sulfuric Acid ◽  
Corrosion Mechanism ◽  
Alkali Activated Concrete ◽  
Alkali Activated

Metabolism and Distribution of Novel Tumor Targeting Drugs In Vivo

2020 ◽  
Vol 21 (13) ◽  
pp. 996-1008
Author(s):  
Mengli Wang ◽  
Qiuzheng Du ◽  
Lihua Zuo ◽  
Peng Xue ◽  
Chao Lan ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Small Molecule ◽  
High Efficiency ◽  
Tumor Therapy ◽  
Research Progress ◽  
Future Research ◽  
Pharmacokinetic Parameters ◽  
Molecular Characteristics ◽  
Targeted Drugs

Background: As a new tumor therapy, targeted therapy is becoming a hot topic due to its high efficiency and low toxicity. Drug effects of targeted tumor drugs are closely related to pharmacokinetics, so it is important to understand their distribution and metabolism in vivo. Methods: A systematic review of the literature on the metabolism and distribution of targeted drugs over the past 20 years was conducted, and the pharmacokinetic parameters of approved targeted drugs were summarized in combination with the FDA's drug instructions. Targeting drugs are divided into two categories: small molecule inhibitors and monoclonal antibodies. Novel targeting drugs and their mechanisms of action, which have been developed in recent years, are summarized. The distribution and metabolic processes of each drug in the human body are reviewed. Results: In this review, we found that the distribution and metabolism of small molecule kinase inhibitors (TKI) and monoclonal antibodies (mAb) showed different characteristics based on the differences of action mechanism and molecular characteristics. TKI absorbed rapidly (Tmax ≈ 1-4 h) and distributed in large amounts (Vd > 100 L). It was mainly oxidized and reduced by cytochrome P450 CYP3A4. However, due to the large molecular diameter, mAb was distributed to tissues slowly, and the volume of distribution was usually very low (Vd < 10 L). It was mainly hydrolyzed and metabolized into peptides and amino acids by protease hydrolysis. In addition, some of the latest drugs are still in clinical trials, and the in vivo process still needs further study. Conclusion: According to the summary of the research progress of the existing targeting drugs, it is found that they have high specificity, but there are still deficiencies in drug resistance and safety. Therefore, the development of safer and more effective targeted drugs is the future research direction. Meanwhile, this study also provides a theoretical basis for clinical accurate drug delivery.

Mix Networks: Existing Scenarios and Future Directions on Security and Privacy

2019 ◽  
Vol 14 ◽  
Author(s):  
Khaleel Ahmad ◽  
Afsar Kamal
Keyword(s):  
Security And Privacy ◽  
Research Progress ◽  
Future Research ◽  
Future Directions ◽  
Practical Solution ◽  
Research Gap ◽  
The Web ◽  
Privacy Enhancing Techniques

Background: Privacy enhancing techniques are developed in order to provide strong protection to cyberspace. These techniques aim to allow users to keep their identities hidden during the communication when they are sending email, making payments online, browsing the Web or posting to newsgroups. MixNet is the most practical solution for concealing identities of message and sender’s identities. Objective: It provides sender and receiver anonymity as well as message security. The main goal of MixNet is to overcome vulnerability and enhance the performance of communication. It can efficiently handle the messages of various length and produce desirable results with privacy. The main objective of this paper is to acquire information and concepts regarding MixNet. We also provide guidelines for future research and references. Methods : The designing of MixNet depends on what cryptosystem method is used. Symmetric and Asymmetric both are used. Other methods could be also used such as PIR, CSP and FDR model, RPC, Token-based approach or others. Result: In this paper we provide an overview of MixNet approaches and presented a survey on MixNet based techniques and different models. We also constructed the comparison tables as per our requirements for better understanding. For this purpose, we found a total of 120 articles related to the MixNet published between 1990 and 2018 from the most relevant scientific resources. However, only 86 papers were analyzed due to comprehensiveness and relevancy to this article. Conclusion: Focused on the security and privacy of communication and how it can be achieved. This survey also reveals research progress and research gap on MixNet.

scholarly journals Research on the Operating Characteristics of Hydraulic Free-Piston Engines: A Systematic Review and Meta-Analysis

Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3530
Author(s):  
Fukang Ma ◽  
Shuanlu Zhang ◽  
Zhenfeng Zhao ◽  
Yifang Wang
Keyword(s):  
Systematic Review ◽  
High Efficiency ◽  
Meta Analysis ◽  
Combustion Process ◽  
Research Progress ◽  
Future Research ◽  
Operating Characteristics ◽  
Piston Engine ◽  
Free Piston ◽  
Free Piston Engine

The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation. Therefore, our study aimed to assess the operating characteristics, core questions and research progress of HFPEs via a systematic review and meta-analysis. We included operational control, starting characteristics, misfire characteristics, in-cylinder working processes and operating stability. We conducted the literature search using electronic databases. The research on HFPEs has mainly concentrated on four kinds of free-piston engine, according to piston arrangement form: single piston, dual pistons, opposed pistons and four-cylinder complex configuration. HFPE research in China is mainly conducted in Zhejiang University, Tianjin University, Jilin University and the Beijing Institute of Technology. In addition, in China, research has mainly focused on the in-cylinder combustion process while a piston is free by considering in-cylinder combustion machinery and piston dynamics. Regarding future research, it is very important that we solve the instabilities brought about by chance fluctuations in the combustion process, which will involve the hydraulic system’s efficiency, the cyclical variation, the method of predicting instability and the recovery after instability.

scholarly journals Integration of Digital Economy and Circular Economy: Current Status and Future Directions

2021 ◽  
Vol 13 (13) ◽  
pp. 7217
Author(s):  
Zhen Liu ◽  
Jing Liu ◽  
Mohamed Osmani
Keyword(s):  
Circular Economy ◽  
Digital Technology ◽  
Global Economy ◽  
Digital Economy ◽  
Research Field ◽  
Research Progress ◽  
Current Status ◽  
Future Research ◽  
Disruptive Effect ◽  
The European Union

Circular economy (CE) is a concept actively advocated by the European Union (EU), China, Japan, and the United Kingdom. At present, CE is considered to grant the most traction for companies to achieve sustainable development. However, CE is still rarely adopted by enterprises. As the backbone of the fourth industrial revolution, the digital economy (DE) is considered to have a disruptive effect. Studies have shown that digital technology has great potential in promoting the development of CE. Especially during the COVID-19 epidemic that has severely negatively affected the global economy, environment, and society, CE and DE are receiving high attention from policy makers, practitioners, and scholars around the world. However, the integration of CE and digital technology is a small and rapidly developing research field that is still in its infancy. Although there is a large amount of research in the fields of CE and DE, respectively, there are few studies that look into integrating these two fields. Therefore, the purpose of this paper is to explore the research progress and trends of the integration of CE and DE, and provide an overview for future research. This paper adopts a bibliometric research method, employs the Web of Science database as its literature source, and uses VOSviewer visual software to carry out keyword co-occurrence analysis, which focuses on publication trends, journal sources, keyword visualization, multidisciplinary areas, life cycle stages, and application fields.

Synthesis of rubberized Alkali-activated Concrete: Experimental and numerical evaluation

2021 ◽  
Vol 303 ◽  
pp. 124526
Author(s):  
Mohammed Yahya Mohammed Al-Fasih ◽  
Ghasan Fahim Huseien ◽  
Izni Syahrizal bin Ibrahim ◽  
Abdul Rahman Mohd Sam ◽  
Hassan Amer Algaifi ◽  
...  
Keyword(s):  
Numerical Evaluation ◽  
Alkali Activated Concrete ◽  
Alkali Activated
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