scholarly journals Addressing Different Needs: The Challenges Faced by India as the Largest Vaccine Manufacturer While Conducting the World’s Biggest COVID-19 Vaccination Campaign

Epidemiologia ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 454-470
Author(s):  
Cinja Nadana Koller ◽  
Cléo Josephine Schwerzmann ◽  
Alexia Suzanne Aimée Lang ◽  
Eleni Alexiou ◽  
Jaya Krishnakumar
Keyword(s):  
Vaccination Campaign ◽  
Grey Literature ◽  
Vaccination Strategy ◽  
Numerical Comparison ◽  
News Reports ◽  
Vaccine Manufacturer ◽  
Production And Distribution ◽  
Current Production ◽  
Production Capacities

The COVID-19 pandemic has highlighted some of the challenges that countries face when balancing domestic and global necessities, for example with regard to vaccine needs, production and distribution. As India hosts one of the world’s largest vaccine manufacturing industries and has one of the most extensive vaccination strategies, the country is particularly exposed to these challenges. This has become all the more obvious as the country experienced a second pandemic wave in the first half of 2021, which has led to a total ban on exports of COVID-19 vaccines. An analysis of the national vaccination strategy and the domestic vaccine industry through review of peer-reviewed literature, grey literature, and news reports showed the fragile balance between domestic and international needs. A numerical comparison of India’s domestic COVID-19 vaccine needs, export agreements, and production capacities was conducted. It was found that at current production rates as of April 2021, meeting all of the needs and complying with all of the agreements would be impossible. Scale-ups in production, as promised by the industry, however, will enable the achievement of all targets in the long term.

Near Term Deployment, Long Term Impact: Uranium Price Over the Lifetime of New Capacity

2008 ◽  
Author(s):  
Erich A. Schneider ◽  
Neil Shah
Keyword(s):  
The United States ◽  
Past Century ◽  
Price Forecasting ◽  
Current Production ◽  
Ore Grades ◽  
Past Data ◽  
Near Term ◽  
Long Term Impact ◽  
Production Capacities

While reasonable short-term resource price projections can be obtained by taking a bottom-up approach — constructing a supply curve based upon current production capacities and costs — this approach breaks down as the time horizon of the analysis lengthens. One approach to long-term price forecasting is to calibrate a simple model of a commodity market against past data. To that end, an analogy was drawn between the behavior of the uranium market and that of some three dozen materials for which the United States Geologic Survey (USGS) maintains data. This work adds to previously published results showing that the USGS-reported prices of minerals similar to uranium have consistently declined over the past century. In this paper, the extent to which uranium geology and extraction technologies are indeed analogous to other minerals is quantitatively addressed. A study of crustal abundances, ore grades being economically mined, concentration factors, market share of extraction techniques, years of proven reserve and other factors indicates that uranium is not at all exceptional with respect to the average of the USGS minerals. This suggests that, on the supply side, the analogy between the USGS minerals and uranium may indeed offer valuable insights into medium and long term uranium price behavior.

EUROPEAN UNION´S SUGAR MARKET CONCENTRATION UNDER THE SUGAR QUOTA PRODUCTION SYSTEM

2015 ◽  
Author(s):  
Ľuboš SMUTKA ◽  
Helena ŘEZBOVÁ ◽  
Patrik ROVNÝ
Keyword(s):  
United Kingdom ◽  
Quota System ◽  
Eu Member States ◽  
The United Kingdom ◽  
Sugar Market ◽  
Current Production ◽  
High Dynamic ◽  
Production Capacities ◽  
Very High ◽  
The Eu

The European sugar beet quota system is in very high dynamic process in recent years. The number of sugar companies involved in this system has been constantly decreasing. The aim of this paper is to define subjects (companies/alliances), which possess the current production capacities working under the production quotas system. The paper is determining especially the level of beet sugar production quota holder system concentration using the Herfindahl-Hirschman Index. The paper provides the following findings. The European quota holder system is extremely concentrated and it is becoming more and more dominated by fewer players. Sugar quota is distributed among 19 EU-Member States. In this regard, the quota is generous, especially in relation to France, Germany, Poland and United Kingdom. In Finland, Lithuania, Hungary, Sweden, Denmark, the Netherlands, Slovakia and the United Kingdom controlled by two or even one subject (companies, alliances). There is a large discrepancy between political efforts to distribute equitable R 1308/2013-sugar quotas among states and the actual reality of those distributions. While the EU-quota holder system does not indicate an extreme concentration, an analysis according to the headquarters´ location and allocated quotas to owners of production capacities provides the evidence of extreme concentration.

scholarly journals Anti-meningococcal B vaccination in Italian adolescents: a cost-effective health opportunity

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
D Panatto ◽  
P Landa ◽  
D Amicizia ◽  
P L Lai ◽  
E Lecini ◽  
...  
Keyword(s):  
Large Scale ◽  
Public Health Problem ◽  
Vaccination Strategy ◽  
Cost Effective ◽  
Dose Schedule ◽  
Developed Countries ◽  
Invasive Disease ◽  
International Setting ◽  
The Impact

Abstract Background Invasive disease due to Neisseria meningitidis (Nm) is a serious public health problem even in developed countries, owing to its high lethality rate (8-15%) and the invalidating sequelae suffered by many (up to 60%) survivors. As the microorganism is transmitted via the airborne route, the only available weapon in the fight against Nm invasive disease is vaccination. Our aim was to carry out an HTA to evaluate the costs and benefits of anti-meningococcal B (MenB) vaccination with Trumenba® in adolescents in Italy, while also considering the impact of this new vaccination strategy on organizational and ethics aspects. Methods A lifetime Markov model was developed. MenB vaccination with the two-dose schedule of Trumenba® in adolescents was compared with 'non-vaccination'. Two perspectives were considered: the National Health Service (NHS) and society. Three disease phases were defined: acute, post-acute and long-term. Epidemiological, economic and health utilities data were taken from Italian and international literature. The analysis was conducted by means of Microsoft Excel 2010®. Results Our study indicated that vaccinating adolescents (11th year of life) with Trumenba® was cost-effective with an ICER = € 7,912/QALY from the NHS perspective and € 7,758/QALY from the perspective of society. Vaccinating adolescents reduces the number of cases of disease due to meningococcus B in one of the periods of highest incidence of the disease, resulting in significant economic and health savings. Conclusions This is the first study to evaluate the overall impact of free MenB vaccination in adolescents both in Italy and in the international setting. Although cases of invasive disease due to meningococcus B are few, if the overall impact of the disease is adequately considered, it becomes clear that including anti-meningococcal B vaccination into the immunization program for adolescents is strongly recommended from the health and economic standpoints. Key messages Free, large-scale MenB vaccination is key to strengthening the global fight against invasive meningococcal disease. Anti-meningococcal B vaccination in adolescents is a cost-effective health opportunity.

scholarly journals Evidence for Publicly Reported Quality Indicators in Residential Long-Term Care: A Systematic Review

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 181-181
Author(s):  
Franziska Zúñiga ◽  
Magdalena Osinska ◽  
Franziska Zuniga
Keyword(s):  
New Zealand ◽  
Quality Indicators ◽  
Long Term Care ◽  
Grey Literature ◽  
Public Reporting ◽  
Assessment Instrument ◽  
Term Care ◽  
Data Set ◽  
Residential Long Term Care

Abstract Quality indicators (QIs) are used internationally to measure, compare and improve quality in residential long-term care. Public reporting of such indicators allows transparency and motivates local quality improvement initiatives. However, little is known about the quality of QIs. In a systematic literature review, we assessed which countries publicly report health-related QIs, whether stakeholders were involved in their development and the evidence concerning their validity and reliability. Most information was found in grey literature, with nine countries (USA, Canada, Australia, New Zealand and five countries in Europe) publicly reporting a total of 66 QIs in areas like mobility, falls, pressure ulcers, continence, pain, weight loss, and physical restraint. While USA, Canada and New Zealand work with QIs from the Resident Assessment Instrument – Minimal Data Set (RAI-MDS), the other countries developed their own QIs. All countries involved stakeholders in some phase of the QI development. However, we only found reports from Canada and Australia on both, the criteria judged (e.g. relevance, influenceability), and the results of structured stakeholder surveys. Interrater reliability was measured for some RAI QIs and for those used in Germany, showing overall good Kappa values (>0.6) except for QIs concerning mobility, falls and urinary tract infection. Validity measures were only found for RAI QIs and were mostly moderate. Although a number of QIs are publicly reported and used for comparison and policy decisions, available evidence is still limited. We need broader and accessible evidence for a responsible use of QIs in public reporting.

scholarly journals Primary healthcare for a long term and sustainable vaccination strategy

BMJ ◽  
2021 ◽  
pp. n650
Author(s):  
Arnaud Chiolero ◽  
Stéphane Cullati ◽  
Valérie Santschi
Keyword(s):  
Primary Healthcare ◽  
Vaccination Strategy

The Trans-Asian Pathways of ‘Oriental Products’: Navigating the prohibition of narcotics between Turkey, China, and Japan, 1918–1938

2021 ◽  
pp. 1-43
Author(s):  
DANIEL-JOSEPH MACARTHUR-SEAL
Keyword(s):  
Twentieth Century ◽  
Linear Trend ◽  
League Of Nations ◽  
Turkish Government ◽  
Medical Market ◽  
Opium Production ◽  
Production And Distribution ◽  
Historic Significance ◽  
Drug Prohibition

Abstract Patterns of opium production and distribution shifted immensely over the course of the twentieth century, with output falling by three-quarters, almost nine-tenths of which now takes place in Afghanistan. Supporters of drug prohibition trumpet the success of this long-term decline and hail the withdrawal of the four largest opium producers—India, China, Iran, and the Ottoman empire—from the non-medical market, but this seemingly linear trend conceals numerous deviations of historic significance. Among the most notable and little known is Turkey's prolonged resistance to international restrictions on the narcotics trade and the efforts of state and non-state networks to substitute Turkish opium for the diminishing supply of once-dominant Indian exports to a still opium-hungry China in the first half of the twentieth century. This article uses neglected League of Nations and Turkish government sources alongside international newspapers and diplomatic reports to demonstrate the extent of connections forged by state and non-state actors between Turkey and East Asia, expanding on recent research on trans-Asian connections in commerce and political thought.

A comparative Study in the Role of Private Sector in Relationships Analysis between Economic Sustainability and COVID-19: Evidence from Iraq and Russia

2021 ◽  
Vol 39 (11) ◽  
Author(s):  
Ali Hazim Altameemi ◽  
Hakeem Hammood Flayyih
Keyword(s):  
Private Sector ◽  
Vaccination Campaign ◽  
Medium Size ◽  
Financial Leverage ◽  
Recovery Strategies ◽  
Production And Distribution ◽  
Twin Crisis ◽  
Analytical Tools ◽  
Global Health Problem

The study is designed to investigate the effect of the twin crisis on the private sector and national outlook of the oil dependent nations of Iraq and Russia. It is specifically aimed to evaluate and compare the recovery strategies put in place to survive the small and medium size enterprise. It is also of specific concern to estimate the end to pressure on this sector resulting from the global health problem. Descriptive and comparative research methods forms the central analytical tools employed to synthesis the research dilemma. A year sample t-test is used to compare the level of pressure on the private sector, recovery strategies, it results, performance of other sectors and macroeconomic performance proxies. As members of Organization of Petroleum Export Countries, Iraq and Russia private sector under performed in 2020. The t-statistic results confirm no significant mean difference in the effect of the 2020 twin crisis on private sector of both nations. However, the findings noted COVID-19 rules abiding (high stringency index) and financial leverage aim to support the agro-sector as the Iraqi economy resilient strategies. Russia though with increase financial leverage, focuses on vaccine production and distribution. It is for this reason that the t-statistic noted a significant different in recovery/infected between both nations. Russia should endeavor to improve its stringency index while furthering its vaccination efforts. Iraq needs to engage more vaccination campaign while keeping an eye on it agro sector.

scholarly journals The ‘community' in community land trusts: the role of community control in pursuing community land trust activism

2021 ◽  
Author(s):  
Jennifer Le
Keyword(s):  
Affordable Housing ◽  
Grey Literature ◽  
Community Control ◽  
Success Factor ◽  
Land Trusts ◽  
Land Trust ◽  
Critical Success ◽  
Housing Costs ◽  
Community Land Trust

Housing in the Greater Toronto and Hamilton Area (GTHA) is increasingly unaffordable due to rising housing costs. Community land trusts (CLTs) have recently emerged as a tool for providing affordable housing in the GTHA. This paper investigated the form that CLTs should take to ensure its long-term success for providing affordable housing. Through an analysis of academic and grey literature, the element of community control was identified as being a critical success factor. This paper explored four CLTs operating in American and European contexts to understand whether and how community control was manifested and the resulting implications it had on the CLT and residents. The findings of the paper confirm the importance of community control in the long-term functioning of CLTs, and that community control can be manifested in various forms. Planners operating in the GTHA must therefore be mindful of ensuring that community control is expressed in CLTs. Keywords: Community land trust; affordable housing; community control; Greater Toronto and Hamilton Area

scholarly journals The First Sale Doctrine and the Economics of Post-Sale Restraints

2016 ◽  
Author(s):  
Ariel Katz
Keyword(s):  
Intellectual Property ◽  
Vertical Integration ◽  
Common Law ◽  
User Innovation ◽  
Opting Out ◽  
Opt Out ◽  
Production And Distribution ◽  
First Sale ◽  
First Sale Doctrine

The first sale doctrine limits the exclusive rights that survive the initial authorized sale of an item protected by intellectual property (IP) rights, and therefore limits the ability of IP owners to impose post-sale restraints on the distribution or use of items embodying their IP. While the doctrine has deep common law and statutory roots, its exact rationale and scope have never been fully explored and articulated. As a result, the law remains somewhat unsettled, in particular with respect to the ability of IP owners to opt-out of the doctrine and with respect to the applicability of the doctrine to situations of parallel importation.This Article provides answers to these unsettled issues. By applying insights from the economics of post-sale restraints, the Article shows that the main benefits of post-sale restraints involve situations of imperfect vertical integration between coproducing or collaborating firms, which occur during the production and distribution phases or shortly thereafter. In such situations, opting out of the first sale doctrine should be permitted. Beyond such limited circumstances, however, the first sale doctrine promotes important social and economic goals: it promotes efficient long-term use and preservation of goods embodying IP and facilitates user-innovation. Therefore, contrary to some other views, I conclude that the economics of post-sale restraints confirm the validity and support the continued vitality of the first sale doctrine.

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