scholarly journals Low Grip Strength and Muscle Mass Increase the Prevalence of Osteopenia and Osteoporosis in Elderly Women

Healthcare ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 476
Author(s):  
Kyujin Lee ◽  
Ji Young Lee ◽  
Yong Hwan Kim
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Elderly Women ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
Strength Group ◽  
Cutoff Values ◽  
Mass Increase

The risk of developing low muscle strength and muscle mass is affected by aging, osteopenia, and osteoporosis and increases with age. The purpose of this study was to investigate the prevalence and cutoff values for osteoporosis and osteopenia according to the level of grip strength and muscle mass associated with sarcopenia. A cross-sectional study was conducted, and data from 734 women aged from 60 to 79 years old who visited the healthcare center from 2016 to 2019 were analyzed. Bone mineral density was measured on the lumbar spine from 1–4 using dual X-ray absorptiometry. Osteopenia and osteoporosis were classified on the basis of a T-score ranging from −1.0 to −2.4 and under −2.5, respectively. The diagnostic criteria for sarcopenia were a grip strength of <18 kg and muscle mass of <5.7 kg/m2 according to the Asian Working Group of Sarcopenia. Logistic regression analysis was used to determine the odds ratio, and the receiver operating characteristic curve was applied for the cutoff values. There were 351 (47.8%) patients with osteopenia and 152 (20.7%) patients with osteoporosis. The prevalence of osteopenia increased 1.593 times in the lowest grip strength group and 1.810 times in the lowest muscle mass group (p < 0.05). For osteoporosis, the lowest grip strength increased 2.512 times and the lowest muscle mass increased 2.875 times, compared to the highest grip strength group. In the sarcopenia group, osteopenia increased 2.451 times and osteoporosis increased 3.137 times, compared to the non-sarcopenia group (p < 0.05). In conclusion, the prevalence of osteoporosis and osteopenia was increased in elderly women with low grip strength and muscle mass.

scholarly journals Correlation between Degenerative Changes and Osteoporosis in Lumbar Spine of Elderly Women in Dhaka city, Bangladesh

2018 ◽  
Vol 10 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Sultana Amena Ferdoucy ◽  
Md Anower Hussain Mian ◽  
Nasrin Akhter ◽  
Md Shafiqul Alam ◽  
MA Sadek
Keyword(s):  
Lumbar Spine ◽  
Elderly Women ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Degenerative Changes ◽  
Mineral Density ◽  
Cross Sectional ◽  
Age Related ◽  
Younger Age ◽  
Study Results

Aims: Degenerative joint diseases and decreased bone mass i.e.  osteoporosis are two common age related skeletal disorders  responsible for pain and disability. Bangladesh has a high incidence  of osteoporosis and the incidence particularly in women, occurs  among a relatively younger age group than in the developed world.  However little is known about the correlation between degenerative  changes and osteoporosis in lumbar spine of elderly women. The  purpose of this study was to clarify this relationship in elderly women  of Dhaka, Bangladesh.  Methods: A cross-sectional study was conducted at the department  of radiology and imaging of Bangladesh institute of research and  rehabilitation in diabetes, endocrine and metabolic disorders  (BIRDEM), Dhaka during the period of 1st January, 2009 to 31st  December, 2010. DEXA scan of spine and BMD measurement were  done at a renowned private hospital of Dhaka. Total 63 elderly female  aged between 50-75 years were randomly selected for this study.  Results: An inverse relationship between osteoporosis and  spondylosis in postmenopausal women as evaluated by bone  mineral density and semiquantitative scoring of spinal degeneration  was observed. A significant negative correlation (r=-0.53:p<0.05)  was found between T-score and grade. DOI: http://dx.doi.org/10.3329/cdcj.v10i1.13740 City Dent. Coll. J Volume-10, Number-1, January-2013

scholarly journals Postural control among elderly women with and without osteoporosis: is there a difference?

2010 ◽  
Vol 128 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Thomaz Nogueira Burke ◽  
Fabio Jorge Renovato França ◽  
Sarah Rúbia Ferreira de Meneses ◽  
Viviam Inhasz Cardoso ◽  
Rosa Maria Rodrigues Pereira ◽  
...  
Keyword(s):  
Postural Control ◽  
Elderly Women ◽  
Center Of Pressure ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Clinical Test ◽  
Mineral Density ◽  
Maximum Displacement ◽  
Cross Sectional ◽  
School Of Medicine

CONTEXT AND OBJECTIVE: Little is known about postural control among elderly individuals with osteoporosis and its relationship with falls. It has been suggested that elderly women with kyphosis and osteoporosis are at greater risk of falling. The aim of this study was to evaluate posture and postural control among elderly women with and without osteoporosis. DESIGN AND SETTING: Cross-sectional study conducted at the Physical Therapy and Electromyography Laboratory, School of Medicine, Universidade de São Paulo (USP). METHODS: Sixty-six elderly women were selected from the bone metabolism disorders clinic, Division of Rheumatology, USP, and were divided into two groups: osteoporosis and controls, according to their bone mineral density (BMD). Postural control was assessed using the Limits of Stability (LOS) test and the Modified Clinical Test of Sensory Interaction and Balance (CTSIBm) and posture, using photometry. RESULTS: The elderly women with osteoporosis swayed at higher velocity on a stable surface with opened eyes (0.30 versus 0.20 degrees/second; P = 0.038). In both groups, the center of pressure (COP) was at 30% in the LOS, but with different placements: 156° in the osteoporosis group and 178° in the controls (P = 0.045). Osteoporosis patients fell more than controls did (1.0 versus 0.0; P = 0.036). CONCLUSIONS: The postural control in elderly women with osteoporosis differed from that of the controls, with higher sway velocity and maximum displacement of COP. Despite postural abnormalities such as hyperkyphosis and forward head, the COP position was posteriorized.

scholarly journals P1586SARCOPENIA IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Armando Luis Negri ◽  
Ruben Abdala ◽  
Elisa Del Valle ◽  
Pablo Bridoux ◽  
Luciana Gonzalez Paganti ◽  
...  
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Hand Grip ◽  
Hand Dynamometer ◽  
And Function

Abstract Background and Aims Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging. These modifications lead to greater morbidity and mortality as a result of falls, hospitalization, depression and dependence among others. Chronic Kidney disease (CKD) and hemodialysis (HD) produce a favorable environment for the development of sarcopenia. Objective: to study the prevalence of sarcopenia and its different components (muscle mass, strength and physical performance) using EWGSOP 2018 proposed criteria. Method cross-sectional study evaluating 100 adult HD patients. We evaluated: Grip strength (GS) with Jamar Hydraulic Hand Dynamometer (three determinations in the arm without fistula); Appendicular lean mass (ALM) by DXA (GE LUNAR Prodigy Advance) and physical performance: Gait-speed (Time needed to perform a 4-meter walk on a flat surface) and the sit-stand test Results 58 males (M) and 42 females (F). Mean age for M was 54.3 years and 58 years for F. The prevalence of sarcopenia was 18% in the whole group, 10% in M and 20% in F. In M 33% had low GS and 26% low ALM. In M GS correlated with ALM, Albumin and weight p&lt;0.05 (R 2 0.41); ALM correlated with weight r 0.75, height r 0.64 and GS r 0.46 (p&lt;0.05). In F, 27% had low GS, 54% low ALM, and 17% poor physical performance. In F, GS correlated positively with ALM; ALM correlated positively with: weight r 0.78, height r 0.66, GS r 0.59 and sit-stand r 0.40 (p&lt;0.5). Patients with lower grip strength had a higher prevalence of falls in the last year (40% two or more falls) p=0.03. Conclusion A significant proportion of dialysis patients had sarcopenia. Low hand grip strength was associated with a higher prevalence of falls. Recognizing sarcopenia in dialysis patients would allow us to develop strategies to prevent falls and other complications.

scholarly journals Urinary pentosidine level is associated with grip strength and gait speed in community-dwelling adults: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kenta Moriwaki ◽  
Hiromi Matsumoto ◽  
Chika Tanimura ◽  
Mari Osaki ◽  
Hideki Nagashima ◽  
...  
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Gait Speed ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Significant Difference ◽  
Student’S T ◽  
Age And Sex

Abstract Background Muscle and bone interactions might be associated with osteoporosis and sarcopenia. Urinary pentosidine and serum 25-hydroxyvitamin D (25(OH)D) might affect muscle and bone interactions. It is unclear whether these biomarkers are affected by age and sex or play a role in muscle and physical functions. We aimed to investigate the association between urinary pentosidine and serum 25(OH)D levels with muscle mass, muscle strength, and physical performance in community-dwelling adults. Methods Two-hundred and fifty-four middle-aged and elderly adults were enrolled. There was no significant difference in age between 97 men (75.0 ± 8.9 years) and 157 women (73.6 ± 8.1 years). The skeletal muscle mass index (SMI), grip strength, and gait speed were assessed. The urinary pentosidine level was measured. We evaluated the association of urinary pentosidine and serum 25(OH)D levels with age and sex (student’s t-test) and correlations between biomarker and each variable (Pearson’s correlation coefficients). Multiple regression analysis was performed with grip strength and gait speed as dependent variables and with age, height, weight, body mass index (BMI), speed of sound (SOS), SMI, glycated hemoglobin (HbA1c), estimated glomerular filtration rate (eGFR), 25(OH)D, and pentosidine as independent variables using the stepwise method. Results The urinary pentosidine level was negatively correlated with grip strength, gait speed, eGFR, and insulin-like growth factor-1 (IGF-1) in men and with SOS, grip strength, and gait speed in women. The serum 25(OH)D level was positively correlated with IGF-1 in women and grip strength in men. Grip strength was associated with age, height, and pentosidine in men and height and pentosidine in women. Gait speed was associated with age, BMI, and pentosidine in men and age, height, and pentosidine in women. Conclusion Urinary pentosidine levels are significantly associated with grip strength and gait speed and may serve as a biomarker of muscle and bone interactions.

scholarly journals AB0251 SARCOPENIA IN MOROCCAN POPULATION WITH RHEUMATOID ARTHRITIS: PREVALENCE AND PREDICTIVE FACTORS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1425.2-1425
Author(s):  
E. Jalila ◽  
H. Azzouzi ◽  
I. Linda
Keyword(s):  
Rheumatoid Arthritis ◽  
Skeletal Muscle ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Cross Sectional Study ◽  
Whole Body ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
Lean Muscle Mass

Background:Patients with rheumatoid arthritis (RA) were at risk for altered body composition with higher prevalence of sarcopenia compared to the general population. Low lean muscle mass may constitute an additional risk factor for altered bone density in RA patients.Objectives:We aimed to study the prevalence of sarcopenia and to assess its predictive factors in Moroccan patients with RA.Methods:We conducted a cross-sectional study over two months in our department of rheumatology. All RA patients fulfilled ACR/EULAR 2010 criteria. We performed a whole-body dual-energy X-ray absorptiometry (DXA) to measure lean mass, fat mass and bone mass in the whole body and body parts. The appendicular skeletal muscle mass was assessed using the sum of skeletal muscle mass in the arms and legs. The relative skeletal muscle mass index (RSMI) was calculated from the appendicular skeletal mass divided by the square of the patient’s height (kg/m2). According to Baumgartner et al, sarcopenia was defined as a relative SMI <5.5 kg/m2on women and <7.26 kg/m2on men. Body mass index (BMI) was measured and patients were classified according to World Health Organization. Disease activity and functional disability were measured using the 28-joint Disease Activity Score (DAS28) with CRP and the Health Assessment Questionnaire (HAQ). Comorbidities and medication use including corticosteroids were also recorded. Data was entered and processed using the IBM SPSS Statistics 20. A univariate analysis as well as multivariate regressions were carried out to assess the association between sarcopenia and lumbar spine and femoral neck (FN) bone mineral density (BMD) and RA characteristics.Results:We included 70 (87.5%) women and 10 (12.5%) men with a mean age of 53.59 ±10.96 years old. They had a mean disease duration of 12.35± 8.68, a mean DAS 28 CRP of 2.64±1.34, a mean HAQ of 0.94±0.63 and a mean RSMI of 5.75±1.17. Women had a mean RSMI of 6.33±1.04 while men had a mean RSMI of 5.66±1.17. The prevalence of sarcopenia in our population was 47.4% (37), of whom 81.1% (30) women.In univariate regression analysis, sarcopenia was associated with normal BMI (OR: 8.59, 95% CI [3.054-24.182], p= 0.000), DAS 28 CRP (OR: 1.78, 95% CI [1.203-2.657], p= 0.004), HAQ (OR: 2.15, 95% CI [1.165-5.433], p= 0.019), lumbar spine BMD (OR: 0.001, 95% CI [0.00001-0.043], p= 0.0004) and FN BMD (OR: 0.000006, 95% CI [0.000-0.002], p= 0,00008 at right FN and OR: 0.00009, 95% CI [0.000001-0.010], p=0.000 at left FN, respectively).In multiple regression analysis, sarcopenia was associated with normal BMI (OR: 11.56, 95% CI [2.754–48.598]), p=0.001 and FN BMD (OR: 0.00, 95% CI [0.000–0.084], p = 0.006).Conclusion:In the present study, sarcopenia was common among RA patients and associated with normal BMI and femoral neck BMD, emphasizing the importance of this modifiable risk factor. Further studies are needed to identify effective means to improve lean muscle mass in patients with RA.References:[1]Mochizuki T et al. Sarcopenia-associated factors in Japanese patients with rheumatoid arthritis: A cross-sectional study. Geriatr. Gerontol. Int. 2019;19 (9), 907-912[2]Okano T et al. Loss of lean body mass affects low bone mineral density in patients with rheumatoid arthritis -results from the TOMORROW study-, Modern Rheumatology. 2017;27(6):1-19.[4]Peggy M. Cawthon. Assessment of Lean Mass and Physical Performance in Sarcopenia. Journal of Clinical Densitometry. 2015;18(4):467-71.Disclosure of Interests:None declared

scholarly journals Anthropometric Prediction Equations for Estimating Muscle Mass of Elderly Women

2018 ◽  
Vol 14 (2) ◽  
pp. 195-204 ◽  
Author(s):  
Maria Dara Novi Handayani ◽  
Ahmad Hamim Sadewa ◽  
Arta Farmawati ◽  
Wasilah Rochmah
Keyword(s):  
Muscle Mass ◽  
Elderly Women ◽  
Cross Sectional Study ◽  
Prediction Equations ◽  
Cross Sectional ◽  
Anal Ysis ◽  
Healthy Elderly ◽  
Arm Circumference ◽  
Significant Difference ◽  
Level Of Agreement

Muscle Mass (MM) has an important role in health and physical performance. There are many MM prediction equations, but none is formulated in Indonesia. This study aimed to develop Anthropometric Equations (AE) prediction for MM. A cross sectional study was used to formulate AE prediction through multiple regression analysis.  The significance of observed differences between predicted and actual MM was tested by t test while level of agreement was assessed by Bland Altman plot. A significant correlation was found between MM and height, body mass index, calf/arm/waist circumferences, and waist hip ratio (p<0.05).  Regression anal¬ysis indicated that age, height, and Mid Arm Circumference (MAC) contributed significantly to MM. The resulting equation was MM (kg) = -10.22+(-.097x age)+(0.16xheight)+(0.30xMAC). There was no significant difference between actual and predicted MM results, and both had significant correlation. These results suggest that age, AP related to MM and AE provide valid prediction of MM for healthy elderly women in Jakarta.

scholarly journals Kekuatan genggam tangan, skor Child Pugh, dan massa otot pada pasien dengan sirosis hati

2018 ◽  
Vol 14 (3) ◽  
pp. 122
Author(s):  
Amanda Trixie Hardigaloeh ◽  
Rino Alvani Gani ◽  
Irsan Hasan ◽  
Andri Sanityoso Sulaiman
Keyword(s):  
Liver Cirrhosis ◽  
Liver Function ◽  
Grip Strength ◽  
Muscle Mass ◽  
Cross Sectional Study ◽  
Hand Grip Strength ◽  
Cost Of Treatment ◽  
Cross Sectional ◽  
Hand Grip

Background: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis.

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