scholarly journals In-Treatment Changes in Quality of Life-Related Variables in Therapeutic Communities for Cocaine Abusers: Are These Changes Associated with Clinical Outcomes?

2021 ◽  
Vol 18 (14) ◽  
pp. 7442
Author(s):  
Francisco González-Saiz ◽  
Esperanza Vergara-Moragues
Keyword(s):  
Quality Of Life ◽  
Treatment Outcomes ◽  
Beck Depression Inventory ◽  
Drug Abusers ◽  
Health Related Quality ◽  
Cohen’S D ◽  
Related Quality ◽  
Health Related ◽  
Cohen's D

Background: Few studies have explored changes in quality of life during the first three months of admission to a therapeutic community for addictions. The objective of this study was to determine the relationship between these changes and treatment outcomes at discharge. Methods: We undertook a prospective longitudinal study of 142 cocaine-dependent patients treated at a therapeutics community. All of these patients reached the 3-month evaluation and were subsequently followed until discharge. All participants completed the following measures: Health-Related Quality of Life for Drug Abusers Test; Beck Depression Inventory; State–Trait Anxiety Inventory; Opiate Treatment Index; Dual Diagnosis and Discharge Checklist. Results: At the 3-month assessment, scores on the Health-Related Quality of Life for Drug Abusers Test had increased significantly (Cohen’s d: 0.92), while scores on the Opiate Treatment Index (Cohen’s d: 0.86) and Beck Depression Inventory (Cohen’s d: 0.20) scales both decreased significantly. A higher proportion of the patients considered to have achieved “clinically relevant” treatment outcomes at discharge versus those without clinically relevant outcomes were considered “recovered” according to the Reliable Change Index. Conclusions: An improvement in quality of life-related variables from baseline to the 3-month assessment was associated with better outcomes at discharge from the therapeutic community. The findings of this study may help us to optimise therapeutic interventions.

scholarly journals Effect of Neoadjuvant Chemoradiotherapy on Health-Related Quality of Life in Esophageal or Junctional Cancer: Results From the Randomized CROSS Trial

2018 ◽  
Vol 36 (3) ◽  
pp. 268-275 ◽  
Author(s):  
Bo Jan Noordman ◽  
Mathilde G.E. Verdam ◽  
Sjoerd M. Lagarde ◽  
Maarten C.C.M. Hulshof ◽  
Pieter van Hagen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neoadjuvant Chemoradiotherapy ◽  
Health Related Quality ◽  
End Points ◽  
Treatment Groups ◽  
Cohen’S D ◽  
Related Quality ◽  
Health Related ◽  
Cohen's D

Purpose To compare pre-agreed health-related quality of life (HRQOL) domains in patients with esophageal or junctional cancer who received neoadjuvant chemoradiotherapy (nCRT) followed by surgery or surgery alone. Secondary aims were to examine the effect of nCRT on HRQOL before surgery and the effect of surgery on HRQOL. Patients and Methods Patients were randomly assigned to nCRT (carboplatin plus paclitaxel with concurrent 41.4-Gy radiotherapy) followed by surgery or surgery alone. HRQOL was measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire–Core 30 (QLQ-C30) and –Oesophageal Cancer Module (QLQ-OES24) questionnaires pretreatment and at 3, 6, 9, and 12 months postoperatively. The nCRT group also received preoperative questionnaires. Physical functioning (PF; QLQ-C30) and eating problems (EA; QLQ-OES24) were chosen as predefined primary end points. Predefined secondary end points were global QOL (GQOL; QLQ-C30), fatigue (FA; QLQ-C30), and emotional problems (EM; QLQ-OES24). Results A total of 363 patients were analyzed. No statistically significant differences in postoperative HRQOL were found between treatment groups. In the nCRT group, PF, EA, GQOL, FA, and EM scores deteriorated 1 week after nCRT (Cohen’s d: −0.93, P < .001; 0.47, P < .001; −0.84, P < .001; 1.45, P < .001; and 0.32, P = .001, respectively). In both treatment groups, all end points declined 3 months postoperatively compared with baseline (Cohen’s d: −1.00, 0.33, −0.47, −0.34, and 0.33, respectively; all P < .001), followed by a continuous gradual improvement. EA, GQOL, and EM were restored to baseline levels during follow-up, whereas PF and FA remained impaired 1 year postoperatively (Cohen’s d: 0.52 and −0.53, respectively; both P < .001). Conclusion Although HRQOL declined during nCRT, no effect of nCRT was apparent on postoperative HRQOL compared with surgery alone. In addition to the improvement in survival, these findings support the view that nCRT according to the Chemoradiotherapy for Esophageal Cancer Followed by Surgery Study–regimen can be regarded as a standard of care.

A Polytomous Rasch Analysis of the English Version of Health-Related Quality of Life for Drug Abusers Test

2015 ◽  
Vol 18 ◽  
Author(s):  
Oscar M. Lozano ◽  
Antonio J. Rojas Tejada ◽  
Katia Foresti ◽  
Carlos Zubaran
Keyword(s):  
Quality Of Life ◽  
Psychometric Properties ◽  
Rasch Model ◽  
Scale Model ◽  
Drug Abusers ◽  
Health Related Quality ◽  
English Version ◽  
Related Quality ◽  
Health Related

AbstractThe specific aim of this study was to analyze the psychometric properties of the English version of the Health-Related Quality of Life for Drug Abusers Test (HRQoLDA Test) applying the Rasch model, and emphasizing fit between empirical data and theoretical Rasch model assumptions; item(s) category probability curve; and precision in terms of information function. In this study, the authors present the results of the translation and adaptation of the original Spanish version to English, as applied to a sample of substance users in Australia. The authors evaluated 121 adults recruited from inpatient and outpatient treatment facilities in Sydney, Australia. The Rating Scale Model was used in the psychometric analysis of the English version of the HRQoLDA Test. The items and persons revealed a fit between the reported data and the model. It was also demonstrated that respondents did not discriminate among the five response categories, which led to a reduction to three response categories. The adaptation of the TECVASP to the English language, renamed the HRQoLDA test, as developed with an Australian sample revealed adequate psychometric properties.

The Italian Spine Youth Quality of Life questionnaire measures health-related quality of life of adolescents with spinal deformities better than the reference standard, the Scoliosis Research Society 22 questionnaire

2019 ◽  
Vol 33 (8) ◽  
pp. 1404-1415 ◽  
Author(s):  
Antonio Caronni ◽  
Sabrina Donzelli ◽  
Fabio Zaina ◽  
Stefano Negrini
Keyword(s):  
Quality Of Life ◽  
Research Society ◽  
Spinal Deformities ◽  
Scoliosis Research Society ◽  
Cohen’S D ◽  
Related Quality ◽  
Health Related ◽  
Cohen's D ◽  
Better Than

Objective: To compare the validity of the Italian Spine Youth Quality of Life (ISYQOL) questionnaire with that of the Scoliosis Research Society 22 (SRS22) questionnaire, the criterion standard for health-related quality of life (HRQOL) measurement in adolescents with spinal deformities. Design: Cross-sectional study. Setting: Outpatient clinic. Subjects: Consecutive adolescents (10–18 years; 541 wearing brace) affected by idiopathic scoliosis (642 females, 100 males) or hyperkyphosis (87 females, 109 males). Interventions: NA. Main measures: The Spearman’s correlation coefficient (rho) between ISYQOL and SRS22 was used to assess ISYQOL concurrent validity. Sex, age, severity, bracing, trunk appearance and deformity type were assessed for known-groups validity. Cohen’s d quantified between-groups differences. Multiple linear regression exploring the effect of sex, age, body mass index (BMI), severity, bone age, trunk appearance, physiotherapy, bracing and sport on HRQOL of scoliosis patients was used to assess concurrent validity further. Results: Satisfactory correlations were found between ISYQOL and SRS22 (scoliosis, rho = 0.71; kyphosis, rho = 0.56). Known-groups validity analysis showed that ISYQOL detects all the between-groups differences detected by SRS22 and a males-females difference undetected by SRS22. ISYQOL Cohen’s d was larger than SRS22 Cohen’s d in three between-groups comparisons and similar in the others. Brace, sport and scoliosis severity were independently related to ISYQOL (linear regression: R2 = 0.23; p < 0.001). Brace, sport and physiotherapy were related to SRS22 ( R2 = 0.17). Conclusions: ISYQOL showed high validity when used to measure HRQOL in adolescents with spinal deformities. Moreover, ISYQOL performs better than SRS22, having better known-groups validity and (contrary to SRS22) detecting the impact of disease severity on HRQOL.

Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: A systematic review

2010 ◽  
Vol 143 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Digna M. Kamalski ◽  
Carlijn E. Hoekstra ◽  
Bert G. van Zanten ◽  
Wilko Grolman ◽  
Maroeska M. Rovers
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Treatment Outcomes ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Disease Specific ◽  
Specific Health

scholarly journals Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq

2015 ◽  
Vol 31 ◽  
pp. 4-8 ◽  
Author(s):  
Juman Abdulelah Dujaili ◽  
Syed Azhar Syed Sulaiman ◽  
Mohamed Azmi Hassali ◽  
Ahmed Awaisu ◽  
Ali Qais Blebil ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Outcomes ◽  
Tuberculosis Treatment ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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