scholarly journals Therapeutic Management of Rare Primary Ovarian Neoplasms: Carcinosarcoma, Leiomyosarcoma, Melanoma and Carcinoid

Author(s):  
Mateusz Kozłowski ◽  
Katarzyna Nowak ◽  
Agnieszka Kordek ◽  
Aneta Cymbaluk-Płoska

Carcinosarcoma, leiomyosarcoma, melanoma and carcinoid as primary tumors in the ovary are extremely rare. In this paper, the authors reviewed the literature from 2010 to 2021, based on specific criteria, to analyze the treatment of these rare ovarian neoplasms. We also aimed to verify whether modern therapies have been found in recent years. For this article, 80 papers were finally selected. The vast majority of the articles were clinical case reports. Despite single mentions of new potential pharmacological treatments, surgery (radical or fertility-sparing) is definitely the mainstay of treatment. There are currently no treatment guidelines for these tumors. A review of the literature has revealed the use of various adjuvant treatments. We, therefore, believe that a more detailed understanding of the biology of these tumors is necessary in order to find new target points for treatment. We would like to emphasize the importance of creating an international database of rare ovarian tumors which would make it possible to gather data from various oncological centers and enable further research into these neoplasms.

2021 ◽  
Vol 81 ◽  
pp. 105720
Author(s):  
Youssef Oukessou ◽  
Yassir Hammouda ◽  
Khadija El Bouhmadi ◽  
Redallah Larbi Abada ◽  
Mohamed Roubal ◽  
...  

2017 ◽  
Vol 7 (2) ◽  
pp. 23
Author(s):  
Yusef A. Syed ◽  
Daniel H. Miller ◽  
Liuyan Jiang ◽  
Arya Bagherpour ◽  
Stephen J. Ko

Thymic neuroendocrine tumors are rare, representing less than 5% of all thymic cancers, and are biologically distinct in histology and behavior. Conclusive treatment guidelines are limited due to a lack of randomized clinical trials. Current literature, consisting mainly of case reports and series, suggests that complete surgical resection combined with adjuvant radiation therapy offers the greatest survival benefit for patients with thymic neuroendocrine tumors (NET). Adjuvant chemotherapy may also delay the onset of distant metastasis. Prognosis is generally poor, particularly in high-grade tumors, as these patients are prone to early metastasis. Here we present the case of a 62-year-old woman who achieved a durable response after undergoing an aggressive multimodal treatment approach for a primary thymic NET that initially presented as chronic cough and mild dyspnea on exertion.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Bassel Hallak ◽  
Salim Bouayed ◽  
Crispin Leishman ◽  
Kishore Sandu

Congenital fourth branchial arch anomalies are uncommon entities. Most of these anomalies are diagnosed in childhood. The majority of cases occur on the left side. The clinical presentation of these anomalies varies with age. A respiratory distress is the usual clinical presentation in neonates, cervical cutaneous fistulas in late childhood or acute suppurative thyroiditis. Multiples diagnostic options have been described with different modalities of treatment. The majority of cases of fourth branchial arch anomalies are described only in case reports. We report a clinical case of recurrent cervical abscess in a young woman due to a residual fistula of fourth branchial arch.


2005 ◽  
Vol 91 (3) ◽  
pp. 283-286 ◽  
Author(s):  
Giovanna Gatti ◽  
Stefano Zurrida ◽  
Daniela Gilardi ◽  
Guillermo Bassani ◽  
Gabriela Rosali dos Santos ◽  
...  

Bladder metastases from solid tumors are rare. Breast carcinoma cells seldom spread to the urinary bladder. We report the case of a patient with invasive breast carcinoma who developed a breast recurrence followed by bone and urinary bladder metastases. Starting from this clinical case we review the available literature on this issue. Only few cases of urinary bladder metastases from primary breast cancer have been reported, although the case reports have increased in recent years. Patients with breast cancer presenting with urinary symptoms should be examined for possible bladder metastases.


2021 ◽  
Vol 15 (58) ◽  
pp. 493-523
Author(s):  
Stella Alves Batista Mendes ◽  
Fernanda Nunes Tomaz ◽  
Fernando De Goes Ladeia

A bichectomia é um procedimento cirúrgico em que remove-se a parte correspondente ao coxim adiposo do Bichat, com finalidades estética e funcional. Tal procedimento está cada vez mais popular na Odontologia. Objetivo: Apresentar uma revisão narrativa da literatura sobre complicações associadas às cirurgias de bichectomia. Materiais e Métodos: Foi realizada uma busca de publicações sem restrição em relação ao ano de publicação em que foram realizados, incluído artigos científicos, relatos de caso clínicos, revisões de literatura, estudos descritivos e observacionais e excluindo cartas ao editor, editorias, teses e manografias  a partir dos descritores em saúde (DeCS) “anatomia” (anatomy), “bichectomia” (bichectomy), “odontologia” (dentistry). Usando as bases de dados Lilacs, SciELO e Pubmed. Conclusão: Bichectomia é um procedimento estético-funcional, que apresenta riscos de complicações potencialmente graves, destacando-se lesão do ducto de Stenon ou do ramo bucal do nervo facial, que provocam, respectivamente, sialocele, fístulas salivares e paralisia bucal temporária ou definitiva, além de hematomas, assimetria facial e infecções pós-operatórias.---Bichectomy is a surgical procedure in which the part corresponding to the fat pad of Bichat is removed, with aesthetic and functional purposes. Such procedure is increasingly popular in dentistry. Objective: To present a narrative review of the literature on complications associated with bichectomy surgery. Materials and Methods: A search for publications was performed without restriction regarding the year of publication, including scientific articles, clinical case reports, literature reviews, descriptive and observational studies and excluding letters to the editor, editorials, theses and manographies from the health descriptors (DeCS) “anatomy” (anatomy), “bichectomy” (bichectomy), “dentistry” (dentistry). Using Lilacs, SciELO and Pubmed databases. Conclusion: Bichectomy is an aesthetic-functional procedure that presents risks of potentially serious complications, especially  damage to the Stenon's   duct  or  the  buccal branch of the facial nerve, which   cause, respectively, sialocele, salivary fistulas and temporary or permanent buccal paralysis, in addition to bruises, facial asymmetry and postoperative infections. 


Author(s):  
Katherine Kozarek ◽  
Ryan Hood

Cardiac tumors are rarely encountered in clinical practice; however, because they affect vital structures, they can have significant consequences. Cardiac tumors are categorized as either primary tumors originating from cardiac tissue or metastatic tumors migrated from other sites; they may infiltrate the atria, ventricles, valves, and coronary arteries, resulting in considerable changes to normal physiology. They may extend beyond the myocardium to the pericardium, great vessels, and mediastinum. Advances in the development of imaging modalities have allowed for expedited diagnostic evaluation of cardiac tumors. Prompt treatment, which often includes surgical intervention, is essential to both alleviate symptoms and prevent harmful sequelae. The intraoperative anesthetic management of a patient with a cardiac mass presents a number of challenges due to altered cardiovascular physiology. Because these tumors occur so infrequently, standardized, evidence-based diagnostic and treatment guidelines have not been developed. The existing data were derived mainly from small case series and case reports. The aggressive nature of the disease warrants further investigation to improve the accuracy of diagnostic modalities and the efficacy of treatment regimens.


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