scholarly journals To Vaccinate or Not to Vaccinate—This Is the Question among Swiss University Students

2021 ◽  
Vol 18 (17) ◽  
pp. 9210
Author(s):  
Julia Dratva ◽  
Aylin Wagner ◽  
Annina Zysset ◽  
Thomas Volken
Keyword(s):  
Vaccine Development ◽  
Herd Immunity ◽  
Vaccination Strategy ◽  
Collective Responsibility ◽  
Subjective Health ◽  
Demographic Characteristics ◽  
Vaccine Hesitancy ◽  
Subjective Health Status ◽  
Vaccination Rates ◽  
Vaccination History

The speed and innovation of the COVID-19 vaccine development has been accompanied by insecurity and skepticism. Young adults’ attitude to vaccination remains under investigation, although herd immunity cannot be reached without them. The HEalth in Students during the Corona pandemic study (HES-C) provided the opportunity to investigate vaccination intention in 1478 students in the sixth survey wave (January 2021), including vaccination intention, psychological antecedents of vaccine hesitancy, trust in government’s vaccination strategy, and vaccination history. Associations with vaccination intention were analyzed with multivariate ordinal regression and predicted margins were calculated adjusting for gender, age, anxiety, health profession, and subjective health status. A third was decided (yes 25.1%, no 7.6%), and 68% were unsure about getting the COVID-19 vaccine when available. Next to demographic characteristics, vaccination history (influenza vaccination OR = 1.39; 95% CI: 1.06–1.83, travel vaccination OR = 1.29; 95% CI: 1.04–1.60), trust in vaccination strategy (OR = 2.40; 95% CI: 1.89–3.05), and 5C dimensions were associated with vaccination intention: confidence (OR = 2.52; 95% CI: 2.09–3.03), complacency (OR = 0.79; 95% CI: 0.66–0.96), calculation (OR = 0.79; 95% CI: 0.70–0.89), constraints (OR = 1.18; 95% CI: 0.99–1.41), and collective responsibility (OR = 4.47; 95% CI: 3.69–5.40). Addressing psychological antecedents and strengthening trust in official strategies through targeted campaigns and interventions may increase decisiveness and result in higher vaccination rates.

scholarly journals COVID-19 Vaccine Hesitancy among the Younger Generation in Japan

2021 ◽  
Vol 18 (21) ◽  
pp. 11702
Author(s):  
Mostafa Saidur Rahim Khan ◽  
Somtip Watanapongvanich ◽  
Yoshihiko Kadoya
Keyword(s):  
Health Status ◽  
Subjective Health ◽  
Vaccine Hesitancy ◽  
Probit Regression ◽  
Subjective Health Status ◽  
Younger Women ◽  
The Future ◽  
Younger Men ◽  
Younger Generation ◽  
University Degree

Japan has vaccinated its older population; a mass vaccination program for younger citizens is underway. Accordingly, this study investigated vaccine hesitancy among younger Japanese citizens. We used online panel survey data from the Hiroshima Institute of Health Economics Research of Hiroshima University and applied probit regression models. Our study found that vaccine hesitancy among younger people was significantly higher than among older people. Moreover, vaccine hesitancy was significantly higher among younger women than younger men and inter-age-group differences in vaccine hesitancy were higher for younger men than for younger women. Regression demonstrated that subjective health status and anxiety about the future were significantly associated with vaccine hesitancy among younger women and younger men of all ages, respectively. Furthermore, marital status, university degree, anxiety about the future, and myopic view of the future had specific associations with vaccine hesitancy among younger women of different ages, while subjective health status, university degree, having children, financial literacy, household income and assets, and myopic view about the future had specific associations with vaccine hesitancy among younger men of varying ages. Therefore, these results suggest that policymakers should consider the diversity among the younger generation while developing effective, tailored communication strategies to reduce their vaccine hesitancy.

scholarly journals Impact of SARS-CoV-2 Vaccines on Covid-19 Incidence and Mortality in the United States

2021 ◽  
Author(s):  
Fang Fang ◽  
John David Clemens ◽  
Zuo-Feng Zhang ◽  
Timothy F. Brewer
Keyword(s):  
Negative Binomial ◽  
Herd Immunity ◽  
The United States ◽  
Vaccination Rate ◽  
Vaccine Hesitancy ◽  
Percentage Increase ◽  
Protective Effects ◽  
Vaccination Rates ◽  
Incidence And Mortality ◽  
Before And After

Background: Despite safe and effective vaccines to prevent Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections and disease, a substantial minority of the US remains resistant to getting vaccinated. It is imperative to know if expanding vaccination rates could reduce community-wide Coronavirus 2019 (COVID-19) disease, not just among those vaccinated. Methods: Negative binomial models were used to estimate associations between U.S. county-level vaccination rates and county-wide COVID-19 incidence and mortality between April 23rd and September 30th, 2021. A two-week lag and a four-week lag were introduced to assess vaccination rate impact on incidence and mortality, respectively. Stratified analyses were performed for county vaccination rates >40%, and before and after Delta became the dominant variant. Findings: Among 3,070 counties, each percentage increase in population vaccination rates reduced county-wide COVID-19 incidence by 0.9% (relative risk (RR) 0.9910 (95% CI: 0.9869, 0.9952)) and mortality by 1.9% (RR 0.9807 (95% CI: 0.9745, 0.9823)). Among counties with vaccination coverage >40%, each percentage increase in vaccination rates reduced COVID-19 disease by 1.5%, RR 0.9850 (95% CI: 0.9793, 0.9952) and mortality by 2.7% (RR 0.9727 (95% CI: 0.9632, 0.9823)). These associations were not observed among counties with <40% vaccination rates. Increasing vaccination rates from 40% to 80% would have reduced COVID-19 cases by 45.4% (RR 0.5458 (95% CI: 0.4335, 0.6873)) and deaths by 67.0% (RR 0.3305 (95% CI: 0.2230, 0.4898)). An estimated 5,989,952 COVID-19 cases could have been prevented and 127,596 lives saved had US population vaccination rates increased from 40% to 80%. Interpretations: Increasing U.S. SARS-CoV-2 vaccination rates results in population-wide reductions in COVID-19 incidence and mortality. Furthermore, increasing vaccination rates above 40% has protective effects among non-vaccinated persons. Given ongoing vaccine hesitancy in the U.S., increasing vaccination rates could better protect the entire community and potentially reach herd immunity. Funding: National Cancer Institute

scholarly journals Lack of trust and social media echo chambers predict COVID-19 vaccine hesitancy

2021 ◽  
Author(s):  
Will Jennings ◽  
Gerry Stoker ◽  
Hannah Willis ◽  
Viktor Valgardsson ◽  
Jen Gaskell ◽  
...  
Keyword(s):  
Social Media ◽  
Focus Groups ◽  
Vaccine Development ◽  
Population Control ◽  
Herd Immunity ◽  
Vaccine Hesitancy ◽  
Media Impact ◽  
Media Companies ◽  
Nationally Representative ◽  
The Uk

AbstractAs COVID-19 vaccines are rolled out across the world, there are growing concerns about the role that trust, belief in conspiracy theories and spread of misinformation through social media impact vaccine hesitancy. We use a nationally representative survey of 1,476 adults in the UK between December 12 to 18, 2020 and five focus groups conducted in the same period. Trust is a core predictor, with distrust in vaccines in general and mistrust in government raising vaccine hesitancy. Trust in health institutions and experts and perceived personal threat are vital, with focus groups revealing that COVID-19 vaccine hesitancy is driven by a misunderstanding of herd immunity as providing protection, fear of rapid vaccine development and side effects, belief the virus is man- made and related to population control. Particularly those who obtain information from relatively unregulated social media sources such as YouTube that have recommendations tailored by watch history are less likely to be willing to become vaccinated. Those who hold general conspiratorial beliefs are less willing to be vaccinated. Since an increasing number of individuals use social media for gathering health information, interventions require action from governments, health officials and social media companies. More attention needs to help people understand their own risks, unpack complex concepts and fill knowledge voids.

scholarly journals Influence of Prior Influenza Vaccination on Current Influenza Vaccine Effectiveness in Children Aged 1 to 5 Years

Vaccines ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1447
Author(s):  
Kazuhiro Matsumoto ◽  
Wakaba Fukushima ◽  
Saeko Morikawa ◽  
Masashi Fujioka ◽  
Tohru Matsushita ◽  
...  
Keyword(s):  
Influenza Vaccination ◽  
Reference Group ◽  
Vaccination Strategy ◽  
Negative Influence ◽  
Vaccine Effectiveness ◽  
Vaccination Status ◽  
Current Season ◽  
Vaccination Rates ◽  
Vaccination History ◽  
Group 2

Background: Although annual influenza vaccination is an important strategy used to prevent influenza-related morbidity and mortality, some studies have reported the negative influence of prior vaccination on vaccine effectiveness (VE) for current seasons. Currently, the influence of prior vaccination is not conclusive, especially in children. Methods: We evaluated the association between current-season VE and prior season vaccination using a test-negative design in children aged 1–5 years presenting at nine outpatient clinics in Japan during the 2016/17 and 2017/18 influenza seasons. Children with influenza-like illness were enrolled prospectively and tested for influenza using real-time RT-PCR. Their recent vaccination history was categorized into six groups according to current vaccination doses (0/1/2) and prior vaccination status (unvaccinated = 0 doses/vaccinated = 1 dose or 2 doses): (1) 0 doses in the current season and unvaccinated in prior seasons (reference group); (2) 0 doses in the current season and vaccinated in a prior season; (3) 1 dose in the current season and unvaccinated in a prior season; (4) 1 dose in the current season and vaccinated in a prior season; (5) 2 doses in the current season and unvaccinated in a prior season, and (6) 2 doses in the current season and vaccinated in a prior season. Results: A total of 799 cases and 1196 controls were analyzed. The median age of the subjects was 3 years, and the proportion of males was 54%. Overall, the vaccination rates (any vaccination in the current season) in the cases and controls were 36% and 53%, respectively. The VEs of the groups were: (2) 29% (95% confidence interval: −25% to 59%); (3) 53% (6% to 76%); (4) 70% (45% to 83%); (5) 56% (32% to 72%), and (6) 61% (42% to 73%). The one- and two-dose VEs of the current season were significant regardless of prior vaccination status. The results did not differ when stratified by influenza subtype/lineage. Conclusion: Prior vaccination did not attenuate the current-season VE in children aged 1 to 5 years, supporting the annual vaccination strategy.

scholarly journals Growing Need for Alternative Covid-19 Vaccination Strategy in the Face of Vaccination Uptake Hesitancy in the United States

2021 ◽  
Vol 7 (4) ◽  
pp. 15-18
Author(s):  
Nura Ikhalea ◽  
◽  
Hafsah Mohammed ◽  
Nura Ikhalea ◽  
Hafsah Mohammed ◽  
...  
Keyword(s):  
Negative Impact ◽  
Herd Immunity ◽  
Vaccination Strategy ◽  
The United States ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Ripple Effect ◽  
The Us ◽  
Legal Strategies ◽  
Vaccine Information

There has been accelerated effort geared towards the swift creation of COVID-19 vaccines; however, this fast pace poses a negative impact on vaccine acceptance. The current US COVID vaccine hesitancy of 23-33% has a ripple effect and makes it impossible to attain community immunity. The primary aim of this study was to assess the current COVID vaccine hesitancy rates and to argue for the need of more effective strategies to improve its uptake in the US. This paper reviewed quantitative peer-reviewed publications assessing COVID vaccine hesitancy in the US. It was revealed that COVID-19 vaccine hesitancy was influenced by myriad factors like gender, education, political affiliation, race and location. Transparency and a mix of communication, local partnerships, incentives and arguably legal strategies can be adopted to attenuate US COVID vaccine hesitancy. Lastly, vulnerable demographics (black Americans and conservatives) need targeted COVID vaccine information. Keywords: Covid 19 Vaccines, Herd Immunity, Vaccine Uptake, Hesitancy and Vaccine Education

scholarly journals Vaccine Confidence and Hesitancy at the Start of COVID-19 Vaccine Deployment in the UK: An Embedded Mixed-Methods Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Chrissy h. Roberts ◽  
Hannah Brindle ◽  
Nina T. Rogers ◽  
Rosalind M. Eggo ◽  
Luisa Enria ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Online Survey ◽  
Vaccine Development ◽  
Collective Responsibility ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Demographic Groups ◽  
Vaccine Confidence ◽  
The Uk ◽  
Dominant Narratives

Background: Approval for the use of COVID-19 vaccines has been granted in a number of countries but there are concerns that vaccine uptake may be low amongst certain groups.Methods: This study used a mixed methods approach based on online survey and an embedded quantitative/qualitative design to explore perceptions and attitudes that were associated with intention to either accept or refuse offers of vaccination in different demographic groups during the early stages of the UK's mass COVID-19 vaccination programme (December 2020). Analysis used multivariate logistic regression, structural text modeling and anthropological assessments.Results: Of 4,535 respondents, 85% (n = 3,859) were willing to have a COVID-19 vaccine. The rapidity of vaccine development and uncertainties about safety were common reasons for COVID-19 vaccine hesitancy. There was no evidence for the widespread influence of mis-information, although broader vaccine hesitancy was associated with intentions to refuse COVID-19 vaccines (OR 20.60, 95% CI 14.20–30.30, p &lt; 0.001). Low levels of trust in the decision-making (OR 1.63, 95% CI 1.08, 2.48, p = 0.021) and truthfulness (OR 8.76, 95% CI 4.15–19.90, p &lt; 0.001) of the UK government were independently associated with higher odds of refusing COVID-19 vaccines. Compared to political centrists, conservatives and liberals were, respectively, more (OR 2.05, 95%CI 1.51–2.80, p &lt; 0.001) and less (OR 0.30, 95% CI 0.22–0.41, p &lt; 0.001) likely to refuse offered vaccines. Those who were willing to be vaccinated cited both personal and public protection as reasons, with some alluding to having a sense of collective responsibility.Conclusion: Dominant narratives of COVID-19 vaccine hesitancy are misconceived as primarily being driven by misinformation. Key indicators of UK vaccine acceptance include prior behaviors, transparency of the scientific process of vaccine development, mistrust in science and leadership and individual political views. Vaccine programmes should leverage the sense of altruism, citizenship and collective responsibility that motivated many participants to get vaccinated.

scholarly journals Psychological predictors of vaccination intentions among U.S. undergraduates and online panel workers during the 2020 COVID-19 pandemic

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0260380
Author(s):  
Suryaa Gupta ◽  
Shoko Watanabe ◽  
Sean M. Laurent
Keyword(s):  
Undergraduate Students ◽  
Herd Immunity ◽  
Past Research ◽  
Collective Responsibility ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Online Panel ◽  
Conspiracy Beliefs ◽  
Flu Vaccine ◽  
To Receive

Objective Availability of safe and effective vaccines against COVID-19 is critical for controlling the pandemic, but herd immunity can only be achieved with high vaccination coverage. The present research examined psychological factors associated with intentions to receive COVID-19 vaccination and whether reluctance towards novel pandemic vaccines are similar to vaccine hesitancy captured by a hypothetical measure used in previous research. Method Study 1 was administered to undergraduate students when COVID-19 was spreading exponentially (February-April 2020). Study 2 was conducted with online panel workers toward the end of the first U.S. wave (July 2020) as a pre-registered replication and extension of Study 1. In both studies, participants (total N = 1,022) rated their willingness to receive the COVID-19 vaccination and to vaccinate a hypothetical child for a fictitious disease, and then responded to various psychological measures. Results In both studies, vaccination intentions were positively associated with past flu vaccine uptake, self-reported vaccine knowledge, vaccine confidence, and sense of collective responsibility. Complacency (not perceiving disease as high-risk), anti-vaccine conspiracy beliefs, perceived vaccine danger, and mistrust in science/scientists were negative correlates of vaccination intentions. Constraints (psychological barriers), calculation (extensive information-searching), analytical thinking, perceived disease vulnerability, self-other overlap, and conservatism were weakly associated with vaccination intentions but not consistently across both studies or vaccine types. Additionally, similar factors were associated with both real and hypothetical vaccination intentions, suggesting that conclusions from pre-COVID vaccine hesitancy research mostly generalize to the current pandemic situation. Conclusion Encouraging flu vaccine uptake, enhancing confidence in a novel vaccine, and fostering a sense of collective responsibility are particularly important as they uniquely predict COVID-19 vaccination intentions. By including both actual pandemic-related hesitancy measures and hypothetical hesitancy measures from past research in the same study, this work provides key context for the generalizability of earlier non-pandemic research.

scholarly journals Influence of heterogeneous age-group contact patterns on critical vaccination rates for herd immunity to SARS-CoV-2

2021 ◽  
Author(s):  
Joan Saldana ◽  
Caterina M Scoglio
Keyword(s):  
Vaccination Coverage ◽  
Herd Immunity ◽  
Age Groups ◽  
Social Contact ◽  
Vaccination Strategy ◽  
Primary Concern ◽  
Vaccination Rates ◽  
Contact Patterns ◽  
Group Contact ◽  
Age Structured

Currently, several western countries have more than half of their population fully vaccinated against COVID-19. At the same time, some of them are experiencing a fourth or even a fifth wave of cases, most of them concentrated in sectors of the populations whose vaccination coverage is lower than the average. So, the initial scenario of vaccine prioritization has given way to a new one where achieving herd immunity is the primary concern. Using an age-structured vaccination model with waning immunity, we show that, under a limited supply of vaccines, a vaccination strategy based on minimizing the basic reproduction number allows for the deployment of a number of vaccine doses lower than the one required for maximizing the vaccination coverage. Such minimization is achieved by giving greater protection to those age groups that, for a given social contact pattern, have smaller fractions of susceptible individuals at the endemic equilibrium without vaccination, that is, to those groups that are more vulnerable to infection.

scholarly journals Lack of Trust, Conspiracy Beliefs, and Social Media Use Predict COVID-19 Vaccine Hesitancy

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 593
Author(s):  
Will Jennings ◽  
Gerry Stoker ◽  
Hannah Bunting ◽  
Viktor Orri Valgarðsson ◽  
Jennifer Gaskell ◽  
...  
Keyword(s):  
Social Media ◽  
Focus Groups ◽  
Vaccine Development ◽  
Population Control ◽  
Herd Immunity ◽  
Vaccine Hesitancy ◽  
Media Companies ◽  
Conspiracy Beliefs ◽  
Nationally Representative ◽  
The Uk

As COVID-19 vaccines are rolled out across the world, there are growing concerns about the roles that trust, belief in conspiracy theories, and spread of misinformation through social media play in impacting vaccine hesitancy. We use a nationally representative survey of 1476 adults in the UK between 12 and 18 December 2020, along with 5 focus groups conducted during the same period. Trust is a core predictor, with distrust in vaccines in general and mistrust in government raising vaccine hesitancy. Trust in health institutions and experts and perceived personal threat are vital, with focus groups revealing that COVID-19 vaccine hesitancy is driven by a misunderstanding of herd immunity as providing protection, fear of rapid vaccine development and side effects, and beliefs that the virus is man-made and used for population control. In particular, those who obtain information from relatively unregulated social media sources—such as YouTube—that have recommendations tailored by watch history, and who hold general conspiratorial beliefs, are less willing to be vaccinated. Since an increasing number of individuals use social media for gathering health information, interventions require action from governments, health officials, and social media companies. More attention needs to be devoted to helping people understand their own risks, unpacking complex concepts, and filling knowledge voids.

scholarly journals The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study

Vaccines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 191
Author(s):  
Jiahao Wang ◽  
Xinran Lu ◽  
Xiaozhen Lai ◽  
Yun Lyu ◽  
Haijun Zhang ◽  
...  
Keyword(s):  
Safety Information ◽  
Herd Immunity ◽  
Vaccine Hesitancy ◽  
Multivariate Logistic Regression ◽  
Chinese Adults ◽  
Vaccine Price ◽  
Cross Sectional ◽  
The Public ◽  
Vaccination History ◽  
High Level

COVID-19 vaccines have been conditionally used in a few countries, including China since December 2020. The present study aimed to examine whether the acceptance of COVID-19 vaccination changed in different COVID-19 epidemic phases in China. Two consecutive surveys were conducted among Chinese adults in March (n = 2058) (severe epidemic phase) and November–December (n = 2013) (well-contained phase, right before the COVID-19 vaccine was conditionally approved) 2020, and 791 respondents were longitudinally followed-up. The attitude, acceptance, and preferences for future COVID-19 vaccination were compared between two epidemic phases. Multivariate logistic regression was used to identify influencing factors of acceptance. Among the 791 respondents longitudinally followed, 91.9% in March and 88.6% of them in November–December 2020 would like to get COVID-19 vaccination in China. In March 58.3% wished to get vaccinated immediately, but the proportion declined to 23.0% in November–December 2020, because more respondents wanted to delay vaccination until the vaccine’s safety was confirmed. Similar results were found by comparing all respondents from the two cross-sectional surveys in different epidemic phases. The risk perception, attitude for the importance of vaccination against COVID-19, vaccination history, valuing doctor’s recommendations, vaccination convenience, or vaccine price in decision-making had impacts on respondents’ intention for immediate vaccination. The public acceptance for COVID-19 vaccination in China sustained at a high level in different COVID-19 epidemic phases. However, the intention of immediate vaccination declined substantially due to concerns about the vaccine’s safety. Information about vaccination safety from authoritative sources, doctor’s recommendations, and vaccination convenience were important in addressing vaccine hesitancy and promoting successful herd immunity for the general population in China.

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