scholarly journals Effects of Performing Applied Muscle Tension during Recovery after Phlebotomy in Young, First-Time Donors: A Pilot Study

2021 ◽  
Vol 18 (19) ◽  
pp. 10541
Author(s):  
Cara H. Y. Cheung ◽  
May L. Khaw ◽  
Wan Shun Leung ◽  
Shing Yau Tam ◽  
Chui Yee Chu ◽  
...  
Keyword(s):  
Matched Control ◽  
Statistical Significance ◽  
Muscle Tension ◽  
Needle Insertion ◽  
Control Group ◽  
Return Rates ◽  
Applied Muscle Tension ◽  
Group A ◽  
First Time ◽  
Larger Sample

Vasovagal reaction (VVR) compromises donor safety and reduces the subsequent return rates. Performing applied muscle tension (AMT) during phlebotomy may reduce the incidence of VVR. However, the effectiveness of performing AMT after phlebotomy to reduce delayed VVR remains unclear. With ethics approval, 12 young, first-time donors (YFTD) were recruited to study the effects on stroke volume (SV), cardiac output (CO) and systemic vascular resistance (SVR) while performing AMT from needle insertion to end of recovery. Measurements from 12 matched control YFTD were used for comparison. Pre-donation anxiety and VVR severity were assessed. Compared to controls, donors who performed AMT had higher SV (Control: 57 mL vs. AMT: 69 mL, p = 0.045), higher CO (Control: 3.7 L·min−1 vs. AMT: 5.2 L·min−1, p = 0.006) and lower SVR (Control: 1962 dyn·s·cm−5 vs. AMT: 1569 dyn·s·cm−5, p = 0.032) during mid-phlebotomy. During recovery, the AMT group retained higher SV, higher CO and lower SVR than the control, but not reaching statistical significance. Practicing AMT during recovery resulted in sustained haemodynamic improvements beyond the donation period, despite the reduction in delayed VVR was insignificant compared to the control group. A larger sample size is needed to validate the effectiveness of performing AMT after donation to mitigate delayed VVR.

scholarly journals The Influence of the Physiotherapeutic Program on Selected Static and Dynamic Foot Indicators and the Balance of Elderly Women Depending on the Ground Stability

2021 ◽  
Vol 18 (9) ◽  
pp. 4660
Author(s):  
Joanna Matla ◽  
Katarzyna Filar-Mierzwa ◽  
Anna Ścisłowska-Czarnecka ◽  
Agnieszka Jankowicz-Szymańska ◽  
Aneta Bac
Keyword(s):  
Elderly Women ◽  
Statistical Significance ◽  
Exercise Program ◽  
Control Group ◽  
Balance Assessment ◽  
Motor Functions ◽  
Static Test ◽  
Group A ◽  
Group B ◽  
The Impact

Seniors are a constantly growing group of people in many societies. It is necessary to develop physiotherapeutic programs to improve their mobility. The aim of this study was to assess the impact of the physiotherapeutic program conducted unstable ground on selected indicators of motor functions of elderly women. Sixty women (60–80 years) participated in the research. Group A (N = 20) underwent a 12-week physiotherapeutic program on stable ground, group B (N = 20) followed an exercise program on unstable ground, and group C (N = 20) (control group) had no therapeutic intervention. The effects of the therapy were assessed by using a FreeMed platform (foot load analysis) and a Biosway balance system. The results were compared using ANOVA (the one-way analysis), the Kruskal–Wallis test and also the post hoc tests (Tukey’s test and the multiple comparison test). In group A, a statistically significant change was observed in the static test and balance assessment, in group B this was observed in the static and dynamic foot tests and balance assessment, in group C, no statistical significance was achieved. The authors’ physiotherapeutic program had a statistically significant effect on changes in the balance and selected indicators of the motor functions of the examined people. Comparing the results before and after the therapy more improvement changes were noted in women training on an unstable ground compared to women training on a stable ground.

Sports Hernia in National Hockey League Players

2012 ◽  
Vol 41 (1) ◽  
pp. 107-110 ◽  
Author(s):  
Andre Jakoi ◽  
Craig O’Neill ◽  
Christopher Damsgaard ◽  
Keith Fehring ◽  
James Tom
Keyword(s):  
Statistical Significance ◽  
Return To Play ◽  
National Hockey League ◽  
Control Group ◽  
Sports Hernia ◽  
Level Of Evidence ◽  
Athletic Pubalgia ◽  
Hockey Players ◽  
Group A ◽  
Group B

Background: Athletic pubalgia is a complex injury that results in loss of play in competitive athletes, especially hockey players. The number of reported sports hernias has been increasing, and the importance of their management is vital. There are no studies reporting whether athletes can return to play at preinjury levels. Purpose: The focus of this study was to evaluate the productivity of professional hockey players before an established athletic pubalgia diagnosis contrasted with the productivity after sports hernia repair. Study Design: Cohort study; Level of evidence, 3. Methods: Professional National Hockey League (NHL) players who were reported to have a sports hernia and who underwent surgery from 2001 to 2008 were identified. Statistics were gathered on the players’ previous 2 full seasons and compared with the statistics 2 full seasons after surgery. Data concerning games played, goals, average time on ice, time of productivity, and assists were gathered. Players were divided into 3 groups: group A incorporated all players, group B were players with 6 or fewer seasons of play, and group C consisted of players with 7 or more seasons of play. A control group was chosen to compare player deterioration or improvement over a career; each player selected for the study had a corresponding control player with the same tenure in his career and position during the same years. Results: Forty-three hockey players were identified to have had sports hernia repairs from 2001 to 2008; ultimately, 80% would return to play 2 or more full seasons. Group A had statistically significant decreases in games played, goals scored, and assists. Versus the control group, the decreases in games played and assists were supported. Statistical analysis showed significant decreases in games played, goals scored, assists, and average time on ice the following 2 seasons in group C, which was also seen in comparison with the control group. Group B (16 players) showed only statistical significance in games played versus the control group. Conclusion: Players who undergo sports hernia surgeries return to play and often perform similar to their presurgery level. Players with over 7 full seasons return but with significant decreases in their overall performance levels. Less veteran players were able to return to play without any statistical decrease in performance and are likely the best candidates for repair once incurring injury.

scholarly journals Use of a Single Wearable Sensor to Evaluate the Effects of Gait and Pelvis Asymmetries on the Components of the Timed Up and Go Test, in Persons with Unilateral Lower Limb Amputation

Sensors ◽  
2021 ◽  
Vol 22 (1) ◽  
pp. 95
Author(s):  
Maria Stella Valle ◽  
Antonino Casabona ◽  
Ilenia Sapienza ◽  
Luca Laudani ◽  
Alessandro Vagnini ◽  
...  
Keyword(s):  
Gait Cycle ◽  
Inertial Sensor ◽  
Three Dimensional ◽  
The Body ◽  
Limb Amputation ◽  
Control Group ◽  
Timed Up And Go ◽  
Physical Mobility ◽  
Group A ◽  
First Time

The Timed Up and Go (TUG) test quantifies physical mobility by measuring the total performance time. In this study, we quantified the single TUG subcomponents and, for the first time, explored the effects of gait cycle and pelvis asymmetries on them. Transfemoral (TF) and transtibial (TT) amputees were compared with a control group. A single wearable inertial sensor, applied to the back, captured kinematic data from the body and pelvis during the 10-m walk test and the TUG test. From these data, two categories of symmetry indexes (SI) were computed: One SI captured the differences between the antero-posterior accelerations of the two sides during the gait cycle, while another set of SI quantified the symmetry over the three-dimensional pelvis motions. Moreover, the total time of the TUG test, the time of each subcomponent, and the velocity of the turning subcomponents were measured. Only the TF amputees showed significant reductions in each SI category when compared to the controls. During the TUG test, the TF group showed a longer duration and velocity reduction mainly over the turning subtasks. However, for all the amputees there were significant correlations between the level of asymmetries and the velocity during the turning tasks. Overall, gait cycle and pelvis asymmetries had a specific detrimental effect on the turning performance instead of on linear walking.

Analysis of Outcome Predictors of Migraine Towards Chronicity

Cephalalgia ◽  
1985 ◽  
Vol 5 (2_suppl) ◽  
pp. 195-199 ◽  
Author(s):  
Anna Baldrati ◽  
Lucia Bini ◽  
Roberto D'Alessandro ◽  
Pietro Cortelli ◽  
Daniela de Capoa ◽  
...  
Keyword(s):  
Chronic Migraine ◽  
Statistical Significance ◽  
Univariate Analysis ◽  
Episodic Migraine ◽  
Control Group ◽  
Outcome Predictors ◽  
Logistic Regression Method ◽  
Group A ◽  
Random Probability

Long-term migraine evolution is still undefined. The poorest outcome is the transformation from episodic attacks to a pattern of daily attacks or continuous headache with intermittent attacks. We called these cases “chronic migraine”. The aim of our study was to investigate whether some clinical variables contributed to migraine chronicity. We interviewed 50 patients with chronic migraine from 2 to 15 years and 90 patients with episodic migraine matched for sex and age as a control group. Univariate analysis revealed two correlations with a chronic outcome: (1) In the control group a significantly higher number of women took oral contraceptives. (2) In the group who developed chronic migraine, there were a greater number of smokers, without reaching statistical significance. The stepwise multiple logistic regression method showed that these two variables influence the prognosis with a maximum likelihood estimate of 65%, hence not much higher than random probability.

scholarly journals Thyroid status, but not insulin status, affects expression of avian uncoupling protein mRNA in chicken

2003 ◽  
Vol 284 (4) ◽  
pp. E771-E777 ◽  
Author(s):  
Anne Collin ◽  
Mohammed Taouis ◽  
Johan Buyse ◽  
Ndey B. Ifuta ◽  
Veerle M. Darras ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Hormonal Regulation ◽  
Uncoupling Protein ◽  
Control Group ◽  
Standard Diet ◽  
Group A ◽  
Diet Control ◽  
The Impact ◽  
First Time ◽  
Uncoupling Protein Mrna

The aim of this study was to investigate the hormonal regulation of the avian homolog of mammalian uncoupling protein (avUCP) by studying the impact of thyroid hormones and insulin on avUCP mRNA expression in chickens ( Gallus gallus). For 3 wk, chicks received either a standard diet (control group), or a standard diet supplemented with triiodothyronine (T3; T3 group) or with the thyroid gland inhibitor methimazole (MMI group). A fourth group received injections of the deiodinase inhibitor iopanoic acid (IOP group). During the 4th wk of age, all animals received two daily injections of either human insulin or saline solution. The results indicate a twofold overexpression of avUCP mRNA in gastrocnemius muscle of T3 birds and a clear downregulation (−74%) in MMI chickens compared with control chickens. Insulin injections had no significant effect on avUCP mRNA expression in chickens. This study describes for the first time induction of avUCP mRNA expression by the thermogenic hormone T3in chickens and supports a possible involvement of avUCP in avian thermogenesis.

Cerebral Mapping in Subjects Suffering from Migraine With Aura

Cephalalgia ◽  
1990 ◽  
Vol 10 (6) ◽  
pp. 279-284 ◽  
Author(s):  
Dante Facchetti ◽  
Claudia Marsile ◽  
Luigi Faggi ◽  
Edoardo Donati ◽  
Agostino Kokodoko ◽  
...  
Keyword(s):  
Migraine With Aura ◽  
Matched Control ◽  
Statistical Significance ◽  
Peak Frequency ◽  
Total Power ◽  
Control Group ◽  
Alpha Band ◽  
Visual Interpretation ◽  
Slow Activity ◽  
Electroencephalographic Activity

Cerebral mapping of the spontaneous electroencephalographic activity was performed in 31 subjects suffering from migraine with aura and the results were compared with those of a matched control group. All the patients were examined during the interictal period. While traditional visual interpretation of EEG records was negative in all but five cases (16.1%) spectral analysis showed an asymmetry in alpha total power over the posterior regions in 13 cases (41.9%) and an asymmetry in alpha band peak frequency in 17 (54.8%). By means of cerebral mapping and statistical significance probability mapping we were able to demonstrate a significant increase in alpha total power in 13 cases (41.9%) and a regional increase in delta and theta total power in 20 cases (64.5%). In comparison with the control group, the migraine patients showed a widespread increase in slow activity (theta and delta) mostly over the temporal regions.

scholarly journals Assessing different patterns of laser welding with Nickel-Chromium (Ni-Cr) alloy for structures applicable to fixed prosthesis

2017 ◽  
Vol 20 (2) ◽  
pp. 62
Author(s):  
Jarbas Eduardo Martins ◽  
Fábio V.R. Bastos Neto ◽  
Danilo Antônio Duarte ◽  
Ângela Toshie Araki
Keyword(s):  
Laser Welding ◽  
Statistical Significance ◽  
Welding Process ◽  
Laser Pulses ◽  
Bending Test ◽  
Control Group ◽  
Nickel Chromium ◽  
Significant Difference ◽  
Group A ◽  
Passive Fit

<p><span lang="EN-US">Among all desired requirements to dental prosthesis, marginal adaptation and passive fit are the most important. In some cases, in order to achieve these goals, it is necessary to cut and weld the teeth / implant-supported framework. Nowadays, the laser welding process shows a great advantage in comparison to other methods. The aim of this study was to evaluate the optimal laser welds point that is more appropriate to Ni-Cr prosthetic framework. A total of 60 specimens of Ni-Cr (35 mm x 4 mm) were designed and welded using a Nd:YAG laser device model EV 900. They were fixed in a metal piece 0.27 mm between the ends to be welded. All specimens were welded with 21 laser pulses diametrically opposed (frequency of 1.0Hz, load time 3.0 ms and 0.5 mm of diameter pulse). They were divided into three groups according to the electric current of the laser weld: A – 180A; B – 200A and C – 220A. To determinate the flexural mechanic strength, all specimens were submitted to a three-point bending test. The results obtained were: Group A = 553 Mpa; B = 751 Mpa and C = 802.1 Mpa. The control group was 1040.9 Mpa. ANOVA and Tukey’s test were performed and statistical significance differences were observed between group A and B as well as between group A and C. However, no significant difference was observed between B and C.</span></p>

scholarly journals Activating the interleukin-6-Gp130-STAT3 pathway ameliorates ventricular electrical stability in myocardial infarction rats by modulating neurotransmitters in the paraventricular nucleus

2020 ◽  
Author(s):  
Meng Gao ◽  
Dechun Yin ◽  
Jugang Chen ◽  
Xiufen Qu
Keyword(s):  
Myocardial Infarction ◽  
Paraventricular Nucleus ◽  
Interleukin 6 ◽  
Statistical Significance ◽  
Control Group ◽  
Plasma Norepinephrine ◽  
Inflammatory Factor ◽  
Electrical Stability ◽  
Stat3 Pathway ◽  
Group A

Abstract Background: Malignant ventricular arrhythmia (VA) is the most common cause of death associated with acute myocardial infarction (MI). Recent studies have revealed direct involvement of the paraventricular nucleus (PVN) in the occurrence of VA. However, the underlying mechanisms remain incompletely understood. In this study, we investigated changes in the interleukin-6 (IL-6)-glycoprotein 130-signal transducer and activator of transcription 3 (STAT3) pathway in the PVN during acute MI and the effects of this pathway on ventricular stability. Methods: Rats were divided into a control group, a MI group, a PVN-injected anti-IL-6 antibody group and a PVN-injected SC144 group to observe how IL-6 and its downstream glycoprotein 130-STAT3 pathway in the PVN affect ventricular stability. The left anterior descending coronary artery was ligated to induce MI. After that, an anti-IL-6 antibody and SC144 were injected into the PVNs of rats. All data are expressed as the mean ± SE and were analysed by ANOVA with a post hoc LSD test. p<0.05 was considered to indicate statistical significance. Results: After MI, the concentration of the inflammatory factor IL-6 increased, and its downstream glycoprotein 130-STAT3 pathway was activated in the PVN. After injection of MI rat PVNs with the anti-IL-6 antibody or glycoprotein 130 inhibitor (SC144), glutamate levels increased and γ-aminobutyric acid (GABA) levels decreased in the PVN. Plasma norepinephrine concentrations also increased after treatment, which increased the vulnerability to VA. Conclusions: In summary, IL-6 in the PVN exerts a protective effect in MI rats, and the glycoprotein 130-STAT3 pathway plays a key role in this process. We anticipate that our findings will provide new ideas for the prevention and treatment of arrhythmia after MI.

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