The Influence of the Physiotherapeutic Program on Selected Static and Dynamic Foot Indicators and the Balance of Elderly Women Depending on the Ground Stability

Seniors are a constantly growing group of people in many societies. It is necessary to develop physiotherapeutic programs to improve their mobility. The aim of this study was to assess the impact of the physiotherapeutic program conducted unstable ground on selected indicators of motor functions of elderly women. Sixty women (60–80 years) participated in the research. Group A (N = 20) underwent a 12-week physiotherapeutic program on stable ground, group B (N = 20) followed an exercise program on unstable ground, and group C (N = 20) (control group) had no therapeutic intervention. The effects of the therapy were assessed by using a FreeMed platform (foot load analysis) and a Biosway balance system. The results were compared using ANOVA (the one-way analysis), the Kruskal–Wallis test and also the post hoc tests (Tukey’s test and the multiple comparison test). In group A, a statistically significant change was observed in the static test and balance assessment, in group B this was observed in the static and dynamic foot tests and balance assessment, in group C, no statistical significance was achieved. The authors’ physiotherapeutic program had a statistically significant effect on changes in the balance and selected indicators of the motor functions of the examined people. Comparing the results before and after the therapy more improvement changes were noted in women training on an unstable ground compared to women training on a stable ground.

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Sports Hernia in National Hockey League Players

The American Journal of Sports Medicine ◽

10.1177/0363546512462679 ◽

2012 ◽

Vol 41 (1) ◽

pp. 107-110 ◽

Cited By ~ 30

Author(s):

Andre Jakoi ◽

Craig O’Neill ◽

Christopher Damsgaard ◽

Keith Fehring ◽

James Tom

Keyword(s):

Statistical Significance ◽

Return To Play ◽

National Hockey League ◽

Control Group ◽

Sports Hernia ◽

Level Of Evidence ◽

Athletic Pubalgia ◽

Hockey Players ◽

Group A ◽

Group B

Background: Athletic pubalgia is a complex injury that results in loss of play in competitive athletes, especially hockey players. The number of reported sports hernias has been increasing, and the importance of their management is vital. There are no studies reporting whether athletes can return to play at preinjury levels. Purpose: The focus of this study was to evaluate the productivity of professional hockey players before an established athletic pubalgia diagnosis contrasted with the productivity after sports hernia repair. Study Design: Cohort study; Level of evidence, 3. Methods: Professional National Hockey League (NHL) players who were reported to have a sports hernia and who underwent surgery from 2001 to 2008 were identified. Statistics were gathered on the players’ previous 2 full seasons and compared with the statistics 2 full seasons after surgery. Data concerning games played, goals, average time on ice, time of productivity, and assists were gathered. Players were divided into 3 groups: group A incorporated all players, group B were players with 6 or fewer seasons of play, and group C consisted of players with 7 or more seasons of play. A control group was chosen to compare player deterioration or improvement over a career; each player selected for the study had a corresponding control player with the same tenure in his career and position during the same years. Results: Forty-three hockey players were identified to have had sports hernia repairs from 2001 to 2008; ultimately, 80% would return to play 2 or more full seasons. Group A had statistically significant decreases in games played, goals scored, and assists. Versus the control group, the decreases in games played and assists were supported. Statistical analysis showed significant decreases in games played, goals scored, assists, and average time on ice the following 2 seasons in group C, which was also seen in comparison with the control group. Group B (16 players) showed only statistical significance in games played versus the control group. Conclusion: Players who undergo sports hernia surgeries return to play and often perform similar to their presurgery level. Players with over 7 full seasons return but with significant decreases in their overall performance levels. Less veteran players were able to return to play without any statistical decrease in performance and are likely the best candidates for repair once incurring injury.

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THE IMPACT OF SPORT GAMES EXERCISE PROGRAMS ON THE DEVELOPMENT OF SPECIFIC MOTOR ABILITIES IN ADOLESCENTS WITH INTELLECTUAL IMPAIRMENT

Facta Universitatis Series Physical Education and Sport ◽

10.22190/fupes190508022p ◽

2020 ◽

pp. 249

Author(s):

Aleksandar Pejčić ◽

Miodrag Kocić

Keyword(s):

Motor Skills ◽

Statistical Significance ◽

Exercise Program ◽

Experimental Program ◽

Control Group ◽

Mental Impairment ◽

Motor Abilities ◽

Significant Difference ◽

And Control ◽

The Impact

The aim of this study was to determine the effects of a sports games experimental program on improving specific motor abilities in adolescents with mental impairment. The study was conducted on a sample of 60 adolescents diagnosed with mild mental impairment, divided into two groups (experimental group EG, and control group CG) with an equal number of participants. The special program of sports games lasted for 12 weeks, with a weekly frequency of four times and a duration of 30 minutes per training. The participants of both groups were tested with the same variables within the specific motor skills for the sport of football and basketball. After a twelve-week experimental program of sports games, there were statistically significant improvements in the EG in the variables: SMFS, SMDR, SMCP with a statistical significance of r=0.000. The results of the ANOVA and MANOVA analyses indicated that after the application of the specific sports games program there was a statistically significant difference in the benefits for the EG compared to the CG, in the parameters of specific motor abilities with a statistical significance r=0.000 and the size of the impact. Based on these research results, it can be concluded that a specific exercise program conducted within twelve-week training of specifically dosed sports activities has significantly contributed the development of specific motor skills for football and basketball.

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The Impact of Sex Steroids Inhibiter on Thymic Function Following Hematopoietic Stem Cell Transplantation

Blood ◽

10.1182/blood.v112.11.4599.4599 ◽

2008 ◽

Vol 112 (11) ◽

pp. 4599-4599

Author(s):

Xiaodan Luo ◽

Qifa Liu ◽

Zhiping Fan ◽

Yu Zhang ◽

Juan Ning

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Acute Gvhd ◽

Control Group ◽

Hematopoietic Stem ◽

Thymic Function ◽

Significant Difference ◽

Group A ◽

Group B ◽

The Impact

Abstract Objective To evaluate the impact of luteinizing hormone-releasing hormone (LHRH) on the protection of thymic function after allogenic hematopoietic stem cell transplantation (allo-HSCT). Methods Established model of allogenic murine HSCT (C57BL/6→BALB/c). The severity of acute graft-versus-host-disease (GVHD) was assessed by a clinical scoring system that incorporates five clinical parameters: weight loss, posture, activity, fur texture and skin integrity. The intra-cellular levels of interferon-γ (INFγ), tumor necrosis factor-α (TNFα) and interleukin-1β (IL-1β) in thymocyte were analyzed by protein array and thymic function was evaluated by quantification of signaljoint TCR rearrangement excision circles (sjTRECs). Results Recipients in group A (allogenic mice), B( allogenic LHRH castrated-mice) and C (syngenic mice) all attained hematopoiesis reconstitution. White blood cell counts of mice in groups A, B and C were over 1.0×109/L on day (10.60±1.34), day (9.40±0.55) and day (9.40±0.89), respectively. There was no significant difference among the time of hematopoiesis reconstitution in three groups. The time of acute GVHD occuring was on day +11±0.5 and +14±0.5 posttransplantation, respectively, in groups A and B, and all mice had acute GVHD with the incidence of 100% in groups A and B. The average scores of acute GVHD in groups A and B were (1.56±0.51) and (0.92±0.49), respectively. Acute GVHD scores in group A was significantly higher than that in group B (P=0.000). The levels of INFγ, TNFα and IL-1β in control groups were 1.67±1.76 ng/ml, 1.69±1.07 pg/ml and 5.55±3.56 pg/ml, respectively. The levels of INFγ in groups A, B and C were (10.74±2.55) ng/ml,(6.81±2.33) ng/ml and (5.52±3.96) ng/ml, respectively. The levels of TNFα were (7.51±2.89) pg/ml, (4.30±0.63) pg/ml and (3.36±2.31) pg/ml, respectively. The levels of IL-1β were (25.83±8.91) pg/ml, (19.33±3.03) pg/ml and (11.94±4.00) pg/ml, respectively. There were significant differences in the levels of cytokines between group A and the control group (P=0.000, 0.000, 0.000). The levels of cytokines in group B were significantly higher than those of control group (P 0.010,0.037,0.000). The levels of INFγ in group C were significantly higher than those of the control group (P=0.044). Among groups A, B and C, there were significant differences in the levels of INFγ, TNFα and IL-1β (P=0.001,0.000,0.000). The levels of INFγ and TNFα in group A were significantly higher than those in group B (P=0.041,0.013). The levels of INFγ, TNFα and IL-1β in group A were significantly higher than those in group C (P=0.009, 0.002, 0.000). The analysis of linear regression showed that the average levels of INFγ paralled with aGVHD scores (r2 0.363,P=0.038). The average sjTRECs copies/1000 PBMNCs were (39.41±44.68) in the control group and (12.29±13.02), (58.01±71.82) and (19.61±14.59) in groups A, B and C, respectively. There was no significant difference in the multiple comparisons of peripheral blood levels of sjTRECs among these four groups (P=0.575). Conclusion INFγ ATNFα and IL-1β might be involved in the damage to the thymus by acute GVHD. Sex steroid inhibitor can not only reduce the severity of thymic damage after allo-HSCT, but also reduce the severity of aGVHD and the mechanism might be associated with the reduction of intracellular levels of INFγ and TNFα in thymocyte.

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INVESTIGATING THE IMPACT OF GENRE-BASED TEACHING (GBT) ON EFL LEARNERS� LISTENING IMPROVEMENT

English Review Journal of English Education ◽

10.25134/erjee.v8i1.1818 ◽

2019 ◽

Vol 8 (1) ◽

pp. 11

Author(s):

Ehsan Namaziandost ◽

Sajad Shafiee ◽

Mehdi Nasri

Keyword(s):

Test Group ◽

Control Group ◽

Proficiency Tests ◽

Efl Learners ◽

Fundamental Factor ◽

Group A ◽

Listening Proficiency ◽

Group B ◽

The Impact ◽

Better Than

This study tries to investigate the impact(s) of genre-based teaching (GBT) on Iranian EFL learners� listening proficiency as well as to discover if GBT equally affects the listening proficiency of EFL learners at different proficiency levels. To fulfill this objective, 84 EFL learners were chosen. They were divided into Group A and Group B. Groups A and B consisted of 40 and 44 participants, respectively. Group A was divided into experimental and control groups and performed two listening proficiency tests for pre and posttest. Findings of one-way ANCOVA revealed that experimental group performed better than the control group due to using GBI. As indicated by the proficiency test, Group B was also divided into proficient and less-proficient groups; each one performed two listening tests for pre and posttest. Consequences of one-way ANCOVA showed both groups enhanced from pretest to posttest, however; the proficient group performed outstandingly better than the less-proficient group. The results of this study generally demonstrated that GBT is a pivotal and fundamental factor for improving listening comprehension.

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Some Haematological Observations in Columba Livia Due to Haemoproteus Infection

Indian Journal of Advanced Zoology ◽

10.54105/ijz.a2901.101221 ◽

2021 ◽

pp. 1-2

Author(s):

Nasim Jahan ◽

◽

Ramesh Chandra ◽

Mohd Shoeb ◽

◽

...

Keyword(s):

Columba Livia ◽

Blood Parasites ◽

Control Group ◽

Human Consumption ◽

Human Welfare ◽

Wide Range ◽

Group A ◽

The Common ◽

Group B ◽

The Impact

Birds contribute indirectly to human welfare as majority of them feed on insects and rodents and some are efficient scavengers. Poultry forming is a leading profession which provides nutritive food products for human consumption. However, these valuable resources can be infected with a wide range of blood parasites which may affect their survival and existence. In this study, the impact of Haemoproteus, an intracellular sporozoan parasite of the common pigeon. Columba livia on some heamatological parameters (Hb% and TEC) was examined. The investigations were conducted in two groups of Columba livia. Group A: Control, Group B, Heamoproteus infected. The Hb values (13.410.17gm/100ml) in Group A decline to (10.8±0.37 gm/100ml) in Group B. TEC in Group B also declined to 1.620.05×106/Cmm from the normal values of 2.19±0.02×10/Cmm in Group A. The fall in Hb% was 18.97%. and that in TEC was 24.2%. The values of TEC are more affected (24.2 %) as compared to Hb (18.97%). Being an intracellular parasite, the metabolism of Heamoproteus appears to be directly associated with the cells.

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Impact of the COVID-19 pandemic on patients with rupture of intracranial aneurysm at the Dos de Mayo National Hospital in Lima Peru

Peruvian Journal of Neurosurgery ◽

10.53668/2021.pjns33131 ◽

2021 ◽

Vol 3 (3) ◽

Author(s):

José Luis Acha ◽

◽

Julio Josymar Quispe

Keyword(s):

Intracranial Aneurysm ◽

Control Group ◽

Modified Rankin Scale ◽

National Hospital ◽

Acute Hydrocephalus ◽

Ruptured Aneurysms ◽

Ruptured Intracranial Aneurysm ◽

Group A ◽

Group B ◽

The Impact

Objective: To evaluate the impact on the outcome of patients with a ruptured aneurysm, who are admitted to the Dos de Mayo National Hospital in the context of the COVID-19 pandemic. Methods: 42 operated for ruptured aneurysms were included in the context of the COVID-19 pandemic between March 1 and December 31, 2020 (group A), and a control group of 44 patients operated on between March 1 and December 31, 2019 (group B). Upon admission, the poor neurological status defined by the WFNS> 3, the Fisher IV high-grade tomographic status with intracerebral hematoma or acute hydrocephalus, which required external ventricular drainage (EVD), and the presence of vasospasm were evaluated. The Modified Rankin Scale was evaluated at discharge. Statistical analysis was performed to compare both groups. Results: The rates of poor neurological presentation and complications during the presurgical evolution (intracerebral hemorrhage and acute hydrocephalus that required EVD) were higher in group A (p = 0.002 and p <0.05, respectively). The delay in the admission of the patient to the emergency room to receive treatment was 7.5 days in group A and 4.95 days for group B. All these factors contributed to a lower possibility of recovery in group A, which was correlated with higher Values on the Modified Rankin Scale at discharge for this group (p = 0.04). Conclusion: We did not find national reports on ruptured aneurysms treated in the context of the pandemic, this being one of the first studies that demonstrate the impact of the COVID-19 pandemic in patients with ruptured intracranial aneurysm. The population should be educated on how to act in case of specific symptoms such as sudden intense headache, neurological deficit, or acute chest pain, which should receive timely care, immediate referral, and priority of treatment in referral hospitals in order to reduce morbidity and mortality of complex neurological pathologies. Keywords: Intracranial Aneurysm, Aneurysm, Ruptured, Cerebral Hemorrhage, Pandemics, COVID-19. (Source: MeSH NLM)

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The Impact of Diffusion Tensor Imaging Fiber Tracking of the Corticospinal Tract Based on Navigated Transcranial Magnetic Stimulation on Surgery of Motor-Eloquent Brain Lesions

Neurosurgery ◽

10.1093/neuros/nyx554 ◽

2017 ◽

Vol 83 (4) ◽

pp. 768-782 ◽

Cited By ~ 20

Author(s):

Giovanni Raffa ◽

Alfredo Conti ◽

Antonino Scibilia ◽

Salvatore Massimiliano Cardali ◽

Felice Esposito ◽

...

Keyword(s):

Diffusion Tensor ◽

Karnofsky Performance Status ◽

Performance Status ◽

Motor Deficits ◽

Control Group ◽

Benefit Analysis ◽

Group A ◽

Group B ◽

The Impact ◽

Risk Benefit Analysis

Abstract BACKGROUND Navigated transcranial magnetic stimulation (nTMS) enables preoperative mapping of the motor cortex (M1). The combination of nTMS with diffusion tensor imaging fiber tracking (DTI-FT) of the corticospinal tract (CST) has been described; however, its impact on surgery of motor-eloquent lesions has not been addressed. OBJECTIVE To analyze the impact of nTMS-based mapping on surgery of motor-eloquent lesions. METHODS In this retrospective case-control study, we reviewed the data of patients operated for suspected motor-eloquent lesions between 2012 and 2015. The patients underwent nTMS mapping of M1 and, from 2014, nTMS-based DTI-FT of the CST. The impact on the preoperative risk/benefit analysis, surgical strategy, craniotomy size, extent of resection (EOR), and outcome were compared with a control group. RESULTS We included 35 patients who underwent nTMS mapping of M1 (group A), 35 patients who also underwent nTMS-based DTI-FT of the CST (group B), and a control group composed of 35 patients treated without nTMS (group C). The patients in groups A and B received smaller craniotomies (P = .01; P = .001), had less postoperative seizures (P = .02), and a better postoperative motor performance (P = .04) and Karnofsky Performance Status (P = .009) than the controls. Group B exhibited an improved risk/benefit analysis (P = .006), an increased EOR of nTMS-negative lesions in absence of preoperative motor deficits (P = .01), and less motor and Karnofsky Performance Status worsening in case of preoperative motor deficits (P = .02, P = .03) than group A. CONCLUSION nTMS-based mapping enables a tailored surgical approach for motor-eloquent lesions. It may improve the risk/benefit analysis, EOR and outcome, particularly when nTMS-based DTI-FT is performed.

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Efficacy of Crest Herbal Toothpaste in “Clearing Internal Heat”: A Randomized, Double-Blind Clinical Study

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2013/807801 ◽

2013 ◽

Vol 2013 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Jia-Xu Chen ◽

Yue-Yun Liu ◽

Shao-Xian Wang ◽

Xiao-Hong Li

Keyword(s):

Rating Scale ◽

Statistical Significance ◽

Internal Heat ◽

Control Group ◽

Clinical Test ◽

Double Blind ◽

Intention To Treat ◽

Group A ◽

Group B ◽

Control Group Group

Objective. Evaluation of the efficacy of Crest Herbal Crystal Toothpaste in “clearing internal heat.”Methods. This was a randomized, double-blind, controlled parallel design clinical test of a product that was already on the market. 72 subjects were randomly assigned to control group (group A with Colgate Herbal Salty Toothpaste) or treatment group (group B with Crest Herbal Crystal Toothpaste) with ratio of 1 : 2. Subjects were instructed to brush with 1g toothpaste for 2 minutes each time, 2 times per day in a 4-aweek test period; measurement with the rating scale on the efficacy of “clearing internal heat” for the herbal toothpaste was done at baseline, 2 weeks, and 4 weeks of toothpaste usage.Results. The rating scale on efficacy of “clearing internal heat” for the herbal toothpaste reveals that the primitive points of 72-case intention-to-treat (ITT) analysis and 67-case per-protocol (PP) analysis for subjects in group A and subjects in group B were found to be reduced progressively with statistical significance (P<0.05). The overall effective rates for group A and group B were, respectively, 62.50%, 56.25% (ITT) and 62.50%, 60.64% (PP). The statistical results indicated that the symptoms of fire-heat for both groups of subjects have been improved after application of toothpaste.Conclusion. The efficacy of Crest Herbal Crystal Toothpaste in “clearing internal heat” was confirmed by the trial as compared to Colgate Herbal Salty Toothpaste. And its efficacy was objectively evaluated by the rating scale on efficacy of “clearing internal heat.”

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Weekly evaluation of estrogen α and progesterone receptors in the mammary epithelium of women after the use of combined oral hormonal contraceptives for one month

Mastology ◽

10.29289/259453942020v30s1053 ◽

2020 ◽

Vol 30 (Suppl 1) ◽

Author(s):

Joaquim Teodoro de Araújo ◽

Celso Kazuto Taniguchi ◽

Anastasio Berrentini Junior ◽

Rogério Fenile ◽

Afonso Celso Pinto Nazário

Keyword(s):

Statistical Significance ◽

Progesterone Receptors ◽

Mammary Epithelium ◽

Hormonal Contraceptives ◽

Control Group ◽

Environmental Carcinogens ◽

Paracrine Factors ◽

Increased Risk ◽

Group A ◽

Group B

The increased risk of breast cancer (BC) is the most controversial adverse effect of combined oral hormonal contraceptives (COHC). An evaluation of hormone receptors (HR) revealed that their expressions are inversely proportional to the rate of cell proliferation, with a hierarchy where proliferative cells would be controlled by paracrine factors released by positive HR cells. Thus, the greater the proliferation, the greater the risk of the actions of environmental carcinogens. Compare the expressions by immunohistochemistry (IHC) of estrogen α (ERα) and progesterone receptors (PR) weekly in the mammary epithelium (ME) of patients using COHC for one month with those in the natural cycle. Retrospective cohort study of 118 women, 42 of whom were excluded and with a final sample of 76 women. Study group (A) consisted of 31 users of COHC with 30 µg of ethinyl estradiol (EE) and 150 µg of levonorgestrel (L), and control group (B), 45 non-users of COHC. In parity comparison, the Fisher's exact test was used, and for the mean ages, the Student’s t-test for independent samples. The Generalized Estimation Equation (EEG) model was used to evaluate ERα and PR counts over the four weeks and compare them. The Analysis of Variance (ANOVA) with two fixed factors and the Kolmogorov-Smirnov test were used to compare the total ERα and PR counts. Statistical analyses were performed using the SPSS 20.0 and STATA 12 programs, with a significance level of 5% (p≤0.05). As for age, group B had a mean age of 23.7±5.9 years compared to group A, with a mean age of 20.5±5.1 years, statistically significant p=0.016. With regard to parity, group A presented 83.9% of nulligravida versus 73.3% in group B, with p=0.164 without statistical significance. According to GEE, group A had higher mean percentages of ERα (p<0.001) and PR (p<0.001) when compared to women in the control group. The expressions of the IHC of the ERα and PR in percentages, weekly in the ME of the patients in the users of COHC presented higher mean percentages of ERα and PR, both statistically significant, when compared with non-users.

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Cumulative Effect of Cardiovascular Risk Factors on Regulation of AMPK/SIRT1-PGC-1α-SIRT3 Pathway in the Human Erectile Tissue

Oxidative Medicine and Cellular Longevity ◽

10.1155/2020/1525949 ◽

2020 ◽

Vol 2020 ◽

pp. 1-10

Author(s):

Andressa S. Pereira ◽

Alexandra M. Gouveia ◽

Nuno Tomada ◽

Adriana R. Rodrigues ◽

Delminda Neves

Keyword(s):

Risk Factors ◽

Cellular Response ◽

Disease Risk ◽

Cardiovascular Disease Risk ◽

Corpus Cavernosum ◽

Cumulative Effect ◽

Control Group ◽

Group A ◽

Group B ◽

The Impact

Cardiovascular disease risk factors (CVDRF), especially diabetes mellitus (DM), disrupt oxidative stress response. This condition underlies endothelial dysfunction, early manifested in men as erectile dysfunction. The current study is aimed at elucidating the impact of CVDRF in the oxidation responsive AMPK/SIRT1-PGC-1α-SIRT3 pathway and related miRNAs in the human corpus cavernosum. Human penile tissue fragments from individuals submitted to programmed urological surgeries (n=27), aged 43-63 years, were clustered depending on the presence of CVDRF; the control group included samples from patients without CVDRF, and groups A and B included samples from patients with DM and additional CVDRF, totalizing ≤2 CVDRF (group A) and ≥3 CVDRF (group B). Dual-immunolabelling of SIRT3, SOD2, or GPX1 with α-actin in tissue sections was carried out. The assessment of expression levels of NOX1, phospho-AMPKα, total AMPKα, SIRT1, PGC-1α, SIRT3, SOD2, and GPX1 was performed by western blotting and of miR-200a, miR-34a, miR-421, and miR-206 by real-time PCR. Phospho-AMPKα and SIRT3 expression was found significantly increased in group B relative to other groups, suggesting a marked influence of CVDRF, additional to DM, in the regulation of these enzymes. NOX1 was also increased in group B relative to controls. Only an increasing tendency was observed in the phospho-AMPKα/total AMPKα ratio, SIRT1, and PGC-1α expression in groups A and B when compared with controls. Concerning antioxidant enzymes, GPX1 expression was found incremented in group A, but SOD2 expression was decreased in groups A and B, comparative with controls. Group B presented significantly diminished levels of miR-421 and miR-200a, but only a decreasing trend on miR-34 and miR-206 expression was observed. Taken together, our findings demonstrated that besides DM, additional CVDRF presented a cumulative effect in the cellular response to oxidative unbalance, contributing to AMPK/SIRT1-PGC-1α-SIRT3 pathway activation. SOD2, a major mitochondrial antioxidant defence, did not follow the same variation.

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