scholarly journals Sclerotherapy on Demand with Polidocanol to Treat HHT Nosebleeds

2021 ◽  
Vol 10 (17) ◽  
pp. 3845
Author(s):  
Sol Marcos ◽  
Luisa María Botella ◽  
Virginia Albiñana ◽  
Agustina Arbia ◽  
Anna María de Rosales
Keyword(s):  
Quality Of Life ◽  
Analogue Scale ◽  
Health Condition ◽  
Mean Value ◽  
Hereditary Haemorrhagic Telangiectasia ◽  
Significant Drop ◽  
On Demand ◽  
Before And After ◽  
Euroqol 5D

Epistaxis is the most prevalent clinical symptom in Hereditary Haemorrhagic Telangiectasia (HHT), causing anaemia and decreasing the quality of life (QOL). Since 2013, in Hospital Universitario Fundación Alcorcón, more than 150 HHT patients have been treated by nose sclerotherapy on demand. This study shows the results of 105 patients treated with sclerotherapy between 2017 and 2019. HHT-ESS (epistaxis severity score) was used to measure the severity and frequency of epistaxis. QOL was determined before and after treatment by EuroQol-5D (EQ-5D) and the visual analogue scale (VAS) on the health condition. According to HHT-ESS before treatment, 22 patients presented mild, 35 moderate, and 47 severe epistaxes. Sclerotherapy significantly decreased the frequency and severity of epistaxis, with a significant drop of HHT-ESS in 4.6 points, from 6.23 ± 2.3 to 1.64 ± 1.6. Furthermore, the QOL significantly improved, the EQ-5D scale raised from 0.7 ± 0.26 pre- to 0.92 ± 0.16 post-treatment (p < 0.05). Additionally, VAS mean value showed a significant increase from 4.38 ± 2.4 to 8.35 ± 1.2. The QOL improvement was correlated with the ESS decrease. In conclusion, this study shows that on-demand sclerotherapy at the office significantly reduces HHT epistaxis as well as improved the patients’ QOL.

scholarly journals Quality of Life among Patients with Chronic Venous Disease (CVD) as Measured by the VEINES-QOL/SYM and the EuroQol-5D-5L Questionnaires, A Descriptive-Comparative Design Study

2021 ◽  
pp. 56-71
Author(s):  
Cabahug, Reagan F. ◽  
Montalan, Gina L. ◽  
Yape, Irma Marie P. ◽  
Laurenciana, Maria Cristina M.
Keyword(s):  
Quality Of Life ◽  
Similar Efficacy ◽  
Health Condition ◽  
Chronic Venous Disease ◽  
Venous Disease ◽  
Quality Life ◽  
Before And After ◽  
Euroqol 5D ◽  
Sensitivity Specificity

Objective: To determine the efficacy (sensitivity, specificity, and accuracy) of the VeinesQol/Sym with metric statements fewer than the EQ5D in detecting the quality of life of patients with Chronic Venous Disease (CVD) before and after treatment. Methods: This is a descriptive-comparative design in collecting the necessary data to arrive at conclusions that respond to the specific questions of the study in 2 private hospitals. The responses gathered from patients through EQ5D and VeinesQol/Sym, before and after they received treatment were utilized in describing and comparing the efficacy of the health questionnaires.  Data were further subjected to a comparative analysis to elaborate the efficacy of the VeinesQol/Sym.  Results: A total of 114 CVD patients completed the study after the exclusion of 13 patients due to failure to follow up after eight weeks of treatment. The study showed that VeinesQol/Sym and EQ5D has similar efficacy in determining quality of life of CVD patients. However, VeinesQol/Sym  has higher accuracy (84.96% vs 76.99%), higher sensitivity (87.85% vs 83.87%), detects greater level of impairment in mobility, anxiety/depression, pain and discomfort, disruptions in usual activity and lower quality of current state of health condition than EQ5D Conclusion: With the responses to the metric statements of the indicators of quality life in both VeinesQol/Sym and EQ5D, VeinesQol/Sym was found to have a greater efficacy in establishing the accurate status of quality of life of patients with CVD than the EQ5D.

scholarly journals Quality of life of obstetrics fistula patients before and after surgical repair in the Jimma University Medical Center, Southwest Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tilahun Fufa Debela ◽  
Zerihun Asefa Hordofa ◽  
Aster Berhe Aregawi ◽  
Demisew Amenu Sori
Keyword(s):  
Quality Of Life ◽  
Surgical Repair ◽  
Obstetric Fistula ◽  
Medical Center ◽  
Mean Value ◽  
Significant Difference ◽  
Before And After ◽  
The Mean ◽  
Jimma University

Abstract Background The consequences of obstetric fistula on affected women are more than the medical condition. It has extensive physical, psychological, social, and economic consequences on them. Obstetric fistula affects the entire health and entire life of women. Women suffering from obstetric fistula are often abandoned by her partner, relatives, and the community. This study aimed to determine the quality of life of obstetrics fistula patients before and after surgical repair. Methods Institutional-based prospective, before and after study design was conducted in the Jimma University Medical Center from November 1, 2019–October 30, 2020. A face-to-face interview was conducted with fistula patients who visited Jimma University Medical center, fistula clinic during the study period. All fistula patients were included in the study. Accordingly, 78 women who underwent surgical repair were interviewed. The means and the standard deviation were computed using conventional statistics formulas. The unpaired t-test was used to compare two independent means, and one-way analysis of variance (ANOVA) was used to compare the quality of life before repair and after a successful repair. Linear regression analysis was done for identifying determinants of quality of life. A P value of 0.05 will be considered statistical significance. Result The overall quality of life of women was 58.17 ± 7.2 before the surgical repair and 71.20 ± 10.79 after surgical repair. The result indicates there is a significant difference in the mean value of pre and post-operative (P < 0.001). The overall satisfaction of women with their health status before the surgical repair was 22.5 ± 1.30and it has increased to 53.0 ± .90after surgical repair. The physical health dimension score was 16.51 ± 5.27 before the surgical repair while it has increased to 21.77 ± 5.38 after the surgical repair. The score of the social domain before the surgical repair was 5.19 ± 1.34 and it has increased to 7.13 ± 3.67 after the surgical repair. The score of the environmental health domain was 17.41 ± 2.89 before the surgery while it also increased to 21.65 ± 4.04 after the surgical repair. The results have shown there was a significant difference in the mean values of pre and post-operatives in both social and environmental scores (P < 0.001). The score of the psychological health domain before the surgery was 19.06 ± 1.46 and it was increased to 19.84 ± 3.21 after the surgical repair. The result showed there is a significant difference in mean value pre and post-operative (P = 0.048), though it is a slight improvement compared to other domains. Conclusion The overall quality of life of the patient with fistula was improved after successful surgical repair. Although all domains of quality of life had shown significant improvement after successful surgical repair, the psychological domain showed slight improvement.

scholarly journals The Impact of Revascularisation on Quality of Life in Chronic Mesenteric Ischemia

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
J. T. M. Blauw ◽  
H. A. M. Pastoors ◽  
M. Brusse-Keizer ◽  
R. J. Beuk ◽  
J. J. Kolkman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mesenteric Ischemia ◽  
Health Condition ◽  
Index Score ◽  
Mesenteric Arteries ◽  
Chronic Mesenteric Ischemia ◽  
Abdominal Symptoms ◽  
Before And After ◽  
The Impact

Background. Chronic mesenteric ischemia (CMI) is characterized by long-standing abdominal symptoms due to insufficient mesenteric circulation. Data on the effect of revascularisation on quality of life (QoL) for CMI are scarce. This study is the first to evaluate the impact of revascularisation on quality of life. Methods. Seventy-nine patients with CMI or acute-on-chronic mesenteric ischemia (AoCMI) underwent an intervention of one or more mesenteric arteries between January 2010 and July 2012. QoL before and after intervention was measured with the EuroQol-5D. Preintervention questionnaires were of standard care. Postintervention data were obtained by resending a questionnaire to the patients between February and May 2013. To investigate the clinical relevance of our findings, the minimal clinically important difference (MCID) was used. Since there is no established MCID for CMI, we used the literature reference MCID of inflammatory bowel syndrome (IBS) of 0.074. Results. Fifty-five (69.6%) of 79 patients returned their questionnaire and 23 (29.1%) were completely filled out. There was a significant increase of the median EQ-index score from 0.70 to 0.81 (p=0.02) and a significant reduction of symptoms in the domains usual activities (34.4%) and pain/discomfort (32.3%). There was a significant improvement of 17% in overall current health condition (VAS) (p=0.001). The MCID between baseline and postoperative EQ-5D index score was 0.162, indicating a clinically relevant improvement of quality of life after revascularisation. Conclusion. Quality of life of CMI patients is improved after mesenteric artery revascularisation.

scholarly journals Quality of life, pain and anxiety in patients with nephrostomy tubes

2019 ◽  
Vol 27 ◽  
Author(s):  
Luis Manuel Fernández-Cacho ◽  
Rosa Ayesa-Arriola
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Negative Impact ◽  
Descriptive Study ◽  
Beck Anxiety Inventory ◽  
Moderate Pain ◽  
Euroqol 5D ◽  
The Impact

Objective: to evaluate the impact on the quality of life as well as anxiety and pain in patients with nephrostomy tubes. Method: this is a longitudinal descriptive study performed on a sample of n=150 patients. To evaluate the quality of life, the EuroQol-5D questionnaire was used; anxiety was quantified by the Beck Anxiety Inventory; to study pain, a visual analogue scale was employed. Results: statistically significant differences were found in the quality of life, with its worsening (r = 0.51; p <0.01) when evaluated at the first tube replacement. Patients presented mild to moderate anxiety before the procedure, which was reduced at the first tube replacement, although this difference was not significant (r = 0.028, p = 0.393). Finally, the degree of pain was also significantly reduced (r = 0.13, p<0.01) after six weeks. As for gender, women presented the worst values in the three variables studied (worse quality of life and greater anxiety and pain). Conclusions: nephrostomy tubes have a negative impact on the patient’s quality of life. During the time they live with these tubes, patients have mild to moderate pain and anxiety.

scholarly journals Study of quality of life indicators in patients with atrophic postacne scars after laser ablation techniques

2021 ◽  
Vol 20 (3) ◽  
pp. 67-72
Author(s):  
M. A. Ufimtseva ◽  
N. V. Simonova ◽  
Yu. V. Bochkarev
Keyword(s):  
Quality Of Life ◽  
Laser Ablation ◽  
Mean Value ◽  
Daily Routine ◽  
Strong Impact ◽  
Before And After ◽  
Quality Of Life Index ◽  
Pre Treatment ◽  
The Aesthetic

Introduction. Atrophic postacne scars are a persistent cosmetic defect, cause psychological discomfort, and significantly reduce patients' quality of life. Laser technologies are effectively used for their treatment. The aim of the study was to investigate the quality of life in patients with atrophic post-cancerous scars before and after the use of laser methods of scar correction. Materials and methods. A randomized comparative clinical trial included 120 patients with atrophic postacne scars divided into two comparable groups of 60 patients each. Patients received laser ablation procedures with an Erbium laser (2940 nm). The Dermatological Quality of Life Index (DQLI) questionnaire was used to assess the quality of life before and after the laser procedures. Results. The DICG of patients before treatment ranged from 8 to 17 points and averaged 12.962.05 points. In women the mean value of DICG was 14.221.34 points and was higher compared to men (11.141.45 points) (p0.05). After fractional laser ablation procedures and the procedures of its combination with the treatment of the scar edge with a solid stain, improvement of the DICG scores was observed; intergroup differences were found in self-esteem, in the choice of clothing, in personal and intimate relationships, and in the assessment of daily routine. Discussion. The pre-treatment DICG scores of patients with postacne scars indicate a strong impact of the disease on quality of life. The DICG in women was higher than in men, which may be associated with a greater degree of women's anxiety about the aesthetic condition of the skin and appearance. After treatment, the degree of impact of the disease on patients' quality of life decreased to moderate in both groups. Conclusion. The combined method of treatment contributes to the reduction of DICG compared to fractional ablation procedures, which indicates greater patient satisfaction with the result of these procedures.

scholarly journals Study of inert cellulose powder effect on the nasal mucosa

2011 ◽  
Vol 8 (6) ◽  
pp. 53-57
Author(s):  
I B Angotoeva ◽  
E V Sukhovetchenko ◽  
I B Angotoeva ◽  
E V Suhovetchenko
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Nasal Cavity ◽  
Health Condition ◽  
Cellulose Powder ◽  
Before And After ◽  
Safe Product ◽  
Quality Of Life Index ◽  
Inflammation Signs

Background. To investigate the efficiency, safety of inert cellulose powder in allergic rhinitis, and influence on mucous tunic of nasal cavity. Materials and methods. Two groups of patients were examined in this research (30 healthy volunteers and 30 patients suffering from allergic rhinitis). The following factors of patients' life and health condition were evaluated during the investigation: quality of life, the condition of mucous tunic, mucociliary clearance rate, the ciliabeat frequency of ciliated cylindrical epithelium, the signs of inflammation in the smears of mucous tunic before and after the treatment with Nazaval and Nazaval Plus. The results. Nazaval and Nazaval Plus improved the quality of life index and reduced the inflammation signs of mucous tunic of nasal cavity examined by rhinoscopy and endoscopy. No ciliotoxic effects of preparations on mucous tunic were established. Conclusion. The inert cellulose powder is a highly effective and safe product for the treatment of allergic rhinitis.

scholarly journals Influence of balneophysical therapy on activity, functional capacity, and quality of life in patients with rheumatoid arthritis

2009 ◽  
Vol 137 (3-4) ◽  
pp. 171-174 ◽  
Author(s):  
Sonja Stojanovic ◽  
Aleksandar Dimic ◽  
Bojana Stamenkovic ◽  
Aleksandra Stankovic ◽  
Jovan Nedovic
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Functional Capacity ◽  
Mean Value ◽  
Disease Modifying Antirheumatic Drugs ◽  
Das 28 ◽  
Before And After ◽  
The Mean

Introduction It has been well known that balneophysical therapy has a therapeutic effect on clinical and biological parameters of disease activity in the patients with rheumatoid arthritis (RA). Objective. To determine the influence of balneophysical therapy on functional capacity, activity and quality of life of the patients with RA primarily treated with some of disease modifying antirheumatic drugs. Methods. The study enrolled 73 patients with RA treated with some of disease modifying antirheumatic drugs (Methotrexate in 85% of patients). During hospitalization at the Clinical Rheumatologic Department of the Institute 'Niska Banja', the patients were treated, beside the medicamentous therapy, by hydrotherapy (oligomineral, homeothermic, low radioactive water), mineral peloid therapy, electrotherapy and kinesiotherapy. Before and after balneotherapy, the patients filled in the Health Assessment Questionnaire (HAQ) and the Quality of Life Rheumatoid Arthritis (QOL-RA) scale. The Disease Activity Score (DAS) 28 was used to measure the disease activity before and after balneotherapy. A possible value of HAQ was from 0 to 3, and QOL-RA from 0 to 10. Results. The mean value of the duration of balneophysical therapy was 14.7?4.8 days. We found significant improvement of functional capacity in the patients with RA. The average HAQ score before balneotherapy was 1.07?0.61, and 0.86?0.55 after balneotherapy, which was statistically significantly lower (p<0.05). DAS 28 after balneotherapy was also statistically significantly lower than DAS 28 before balneotherapy: the mean value of DAS 28 before therapy was 6.30?0.81 and after therapy 5.48?0.75 (p<0.001). The quality of life significantly improved after balneophysical therapy: the mean value of QOL-RA scale before therapy was 5.38?1.62 and after therapy 7.35?1.81 (p<0.05). Conclusion. Balneophysical therapy, when properly dosed, is an effective, adjuvant therapy in the patients with RA of mild disease activity. Balneophysical therapy has a positive influence on disease activity, functional capacity and quality of life in the patients with rheumatoid arthritis.

scholarly journals QUALITY OF LIFE AND SYMPTOMS BEFORE AND AFTER SEPTOPLASTY

2020 ◽  
pp. 1-2
Author(s):  
Mohanty D ◽  
Hemanth A. V. V* ◽  
Chandrababu M
Keyword(s):  
Quality Of Life ◽  
Obstructive Sleep Apnea ◽  
Nasal Septum ◽  
Analogue Scale ◽  
Treatment Options ◽  
Deviated Nasal Septum ◽  
Nasal Blockage ◽  
Obstructive Sleep ◽  
Before And After

Background :- The goal of this study is to compare quality of life (Qol) and symptoms in 40 patients with a deviated nasal septum preoperatively and postoperatively. Methods :-All patients reported Qol on symptoms over visual analogue scale (VAS) preoperatively and 3 months after surgery and the results were compared. Conclusion:- Septoplasty leads to a highly signicant improvement in Qol and symptoms. The patients do not reach the same level of Qol as healthy people. All symptoms are reported as mild on VAS postoperatively. Allergic patients tend to report more nasal blockage and facial pressure postoperatively than other patients and a focus on medical treatment should be kept also postoperatively. Patients with obstructive sleep apnea report more trouble with snoring postoperatively and alterative treatment options for snoring may be considered in these patients.

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