scholarly journals Meta-Analysis of In-Vitro Bonding of Glass-Ionomer Restorative Materials to Primary Teeth

Materials ◽  
2021 ◽  
Vol 14 (14) ◽  
pp. 3915
Author(s):  
Tamara Peric ◽  
Evgenija Markovic ◽  
Dejan Markovic ◽  
Bojan Petrovic

Restoration of primary teeth is among the main clinical applications of glass-ionomer cements (GIC). The aim of the study was to review and summarize existing evidence of in vitro bond strength of glass-ionomer (GI) restoratives to enamel and dentin of primary teeth. A literature search was performed in PubMed/Medline, Scopus, Web of Science, Cochrane, and Google Scholar databases to identify studies published until April 2021. The search strategy was: (“glass”) and (“ionomer”) and (“primary” or “deciduous”) and (“bond” or “tensile” or “shear”). Two researchers independently retrieved articles that reported on the bond strength of GIC to primary dentin and/or enamel. The meta-analysis was performed to compare the bond strength values of conventional (C) GIC and resin-modified (RM) GIC to different substrates. From 831 potentially eligible articles, 30 were selected for the full-text examination, and 7 were included in the analysis. Studies were rated at high (3), medium (3), and low (1) risk of bias. RM-GIC showed higher bond strength to primary enamel and dentin compared to the C-GIC. Meta-analysis of in vitro studies, evaluating bonding properties of GI restoratives to primary teeth, suggests the superior performance of RM-GIC. However, there is a lack of studies that examine the properties of novel GI formulations.

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6694
Author(s):  
Flavia Iaculli ◽  
Alessandro Salucci ◽  
Gianni Di Giorgio ◽  
Valeria Luzzi ◽  
Gaetano Ierardo ◽  
...  

Background: Conventional composites are largely used in pediatric restorative dentistry and demonstrate successful clinical outcomes. However, the need for simplification of operative steps in young or uncooperative children demands reliable alternatives. Therefore, the aim of the present systematic review and meta-analysis was to evaluate the in vitro bond strength of glass ionomer cements (GICs) and self-adhesive flowable composites (SFCs) on deciduous teeth. Methods: A comprehensive literature search according to the PRISMA checklist was manually and electronically performed by two independent reviewers through the following databases: MEDLINE/PubMed, Google Scholar, Scopus, and Embase, to include in vitro studies comparing GICs and SFCs bond strength values of restorations on primary teeth. In addition, three groups of meta-analyses were conducted using random-effects models. Results: Three articles meeting the inclusion criteria were selected and subjected to both qualitative and quantitative assessment. No statistically significant difference was found between SFC versus GIC; however, both groups significantly differed with conventional flowable composites (CFs). Conclusions: Despite the absence of significant difference in bond strength values, SFCs may be considered a valid alternative to GICs in the restoration of deciduous teeth, although CFs proved better in vitro performances.


2021 ◽  
Vol 10 (19) ◽  
pp. 1429-1434
Author(s):  
Pooja Singh ◽  
Manish Jha ◽  
Kashika Arora ◽  
Deepa Bhat ◽  
Kiran Awchat ◽  
...  

BACKGROUND With the changing demand in dentistry, a wide range of dental materials is present in the market today. Choosing the best material for a given situation becomes confusing for a clinician. Shear bond strength gives an idea of retentiveness of a material partially. The purpose of the study was to determine and compare shear bond strength (SBS) of packable glass ionomer cement (GIC), resin- modified glass ionomer cement (RMGIC), compomer, and giomer to primary and permanent teeth. METHODS An in-vitro, experimental study was done. 60 freshly extracted permanent first premolars, extracted for orthodontic purpose and 60 freshly extracted over-retained deciduous molars were collected and kept in two groups. Specimens in each group were randomly divided into six subgroups depending on the material to be used. Flat dentinal surface on tooth was prepared over which restorative materials were placed. The prepared specimen was subjected to shear test and the value obtained was compared. Descriptive statistical analysis was performed to calculate the mean shear bond strength of each group. Also, analysis of variance (ANOVA) followed by Tukey’s test was performed with the help of critical difference (CD) at 5 % and 1 % level of significance. The debonded specimen were examined to assess the mode of failure. RESULTS Intragroup comparison for primary teeth showed that composite resin had the highest shear bond strength value (16.21 ± 1.12), followed by Giomer (14.25 ± 1.13), compomer (10.27 ± 1.38), RMGIC (6.06 ± 1.04), packable GIC (3.01 ± 0.85) and conventional GIC (2.94 ± 0.91). In permanent teeth, similar order was seen with composite resin showing highest bond strength (17.82 ± 1.50) followed by Giomer (15.26 ± 1.54), compomer (12.54 ± 1.36), RMGIC (7.00 ± 0.89), packable GIC (3.35 ± 0.98) and conventional GIC (3.30 ± 1.03). Intergroup comparison revealed, the values of shear bond strength (SBS) of all the materials tested was lower in primary teeth. However, the difference was statistically insignificant for conventional GIC and packable GIC. The mode of failure for packable GIC specimens was cohesive within the material, which suggests that the values obtained may not be the strength of the bonded interface but the strength of the material. In RMGIC it was predominantly mixed (cohesive within the material), which indicates that the values obtained were not clearly the strength of the bonded interface but due to inherent weakness of the material. The mode of failure in compomer and Giomer was adhesive failure suggesting that the value obtained was of adhesive bond formed at the interface. CONCLUSIONS Giomer and compomer proved to be the materials with high adhesiveness, so these can be recommended as a suitable restorative material for both primary and permanent teeth. Of the four materials tested, Giomer was found to be the best in terms of SBS in both the primary and permanent teeth. KEY WORDS Compomer, Glomer, Packable GIC, RMGIC, Shear Bond Strength


BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wenchao Zhang ◽  
Xiaolei Ren ◽  
Lin Qi ◽  
Chenghao Zhang ◽  
Chao Tu ◽  
...  

Abstract Background In recent years, emerging studies have demonstrated critical functions and potential clinical applications of long non-coding RNA (lncRNA) in osteosarcoma. To further validate the prognostic value of multiple lncRNAs, we have conducted this updated meta-analysis. Methods Literature retrieval was conducted by searching PubMed, Web of Science and the Cochrane Library (last update by October 2, 2019). A meta-analysis was performed to explore association between lncRNAs expression and overall survival (OS) of osteosarcoma patients. Relationships between lncRNAs expression and other clinicopathological features were also analyzed respectively. Results Overall, 4351 patients from 62 studies were included in this meta-analysis and 25 lncRNAs were identified. Pooled analyses showed that high expression of 14 lncRNAs connoted worse OS, while two lncRNAs were associated with positive outcome. Further, analysis toward osteosarcoma clinicopathologic features demonstrated that overexpression of TUG1 and XIST indicated poor clinical parameters of patients. Conclusions This meta-analysis has elucidated the prognostic potential of 16 lncRNAs in human osteosarcoma. Evidently, desperate expression and functional targets of these lncRNAs offer new approaches for prognosis and therapy of osteosarcoma.


Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 506
Author(s):  
Bernardo Romão ◽  
Ana Luísa Falcomer ◽  
Gabriela Palos ◽  
Sandra Cavalcante ◽  
Raquel Braz Assunção Botelho ◽  
...  

This study aimed to perform a systematic review and meta-analysis of the glycemic index (GI) of gluten-free bread (GFB) and its main ingredients. The systematic review followed PRISMA guidelines, using seven electronic databases (PubMed, EMBASE, Scopus, Science Direct, Web of Science, gray literature research with Google Scholar, and patents with Google Patent tool), from inception to November 2020. Eighteen studies met the inclusion criteria evaluating 132 GFB samples. Five articles tested GI in vivo, eleven in vitro; and two studies tested both methods. The analysis showed that 60.7% (95% CI: 40.2–78.1%) of the samples presented high glycemic indexes, evidencing a high glycemic profile for GFB. Only 18.2% (95% CI: 11.7–27.2%) of the bread samples presented in the studies were classified as a low GI. Meta-analysis presented moderate/low heterogenicity between studies (I2 = 61% and <1% for both high and low GIs) and reinforced the proportion of high GIs. Lower GIs were found in formulations based on Colocasia esculenta flour or enriched with fiber, yogurt and curd cheese, sourdough, psyllium, hydrocolloids, enzymes, fructans, and resistant starch, highlighting the efficacy of these ingredients to lower GFBs’ GI. GFB tends to present high GI, impacting the development of chronic diseases when consumed.


Author(s):  
Valerie Bowser Fajen ◽  
Manville G. Duncanson ◽  
Ram S. Nanda ◽  
G. Frans Currier ◽  
Padmaraj V. Angolkar

2017 ◽  
Vol 18 (1) ◽  
pp. 34-38
Author(s):  
Mojtaba Abdollahi ◽  
Masoumeh Ebrahimi ◽  
Alireza Sarraf Shirazi ◽  
Faraneh Abdolhoseinpour

ABSTRACT Introduction One of the possible mechanisms for the gradual destruction of bond strength in dentin-resin interface, could be due to the demineralized unstable collagen matrix. Use of protease inhibitors, such as tannic acid (TA) could prevent destruction of collagen fibers. The aim of this study was to compare the TA effect on bond strength of etch and rinse and self-etch adhesive systems in the dentin of primary teeth. Materials and methods This in vitro study was done on 40 extracted primary molar teeth. The teeth were sectioned in the mesiodistal direction, and enamel of buccal and lingual surfaces was removed. Samples were randomly divided into four groups: Single bond (SB) + TA, SB, Clearfil SE Bond (CSB) + TA, and CSB. Then, Z250 and Clearfil AP-X composites were cured on the surfaces of SB and CSB groups respectively. After that, all samples were divided into aging and non-aging groups. For 3 months, samples were placed under 1,000 thermal cycles in aging group. Subsequently, the shear bond strengths of all groups were measured by the International testing machine, and failure mode was evaluated by an optical stereomicroscope. Data were analyzed with paired t-test and independent t-test. Results Tannic acid induced a significant reduction in the immediate bond strength of adhesive SB. Meanwhile, TA had no significant effect on shear bond strength of the CSB system. Conclusion Based on our findings, use of TA is not recommended with SB and CSB adhesives on primary teeth. Clinical significance Tannic acid may not be considered in resin restorations of primary teeth. How to cite this article Ebrahimi M, Sarraf Shirazi A, Abdolhoseinpour F, Abdollahi M. Effect of Tannic Acid on Bond Strength of Etch and Rinse and Self-etch Adhesive Systems in Dentin of Primary Teeth. J Contemp Dent Pract 2017;18(1):34-38.


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