scholarly journals Affective Disorder and Functional Status as well as Selected Sociodemographic Characteristics in Patients with Multiple Sclerosis, Parkinson’s Disease and History of Stroke

Medicina ◽  
2020 ◽  
Vol 56 (3) ◽  
pp. 117 ◽  
Author(s):  
Andrzej Knapik ◽  
Ewa Krzystanek ◽  
Justyna Szefler–Derela ◽  
Joanna Siuda ◽  
Jerzy Rottermund ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Status ◽  
Affective Disorders ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Sociodemographic Characteristics ◽  
Stroke Survivors ◽  
Depression And Anxiety ◽  
Diagnostic Threshold ◽  
History Of

The main arguments in support of researching anxiety and depression in patients with chronic somatic diseases are the prevalence of affective disorders in the population, somatic conditions as risk factors of affective disorders and the search for effective preventative and therapeutic strategies. The aim of the study was to determine the association between the functional status, selected sociodemographic characteristics and prevalence as well as severity of anxiety and depression in patients with multiple sclerosis (MS), Parkinson’s disease (PD) and history of stroke (S). Material and methods: Eighty participants (44 women and 36 men) with MS (n = 22), PD (n = 31) and history of stroke (n = 27) were enrolled. All participants completed a questionnaire consisting of metrics, the Katz Index of Independence in Activities of Daily Living and the Hospital Anxiety and Depression Scale (HADS). Results: Fifty-five per cent of all participants did not present with anxiety or depression, 20% scored above the diagnostic threshold on the anxiety scale and 26% scored above the diagnostic threshold on the depression scale. Subgroup analysis revealed that anxiety and depression sufferers were 13.64% and 13.64% of MS patients, respectively; 22.58% and 35.48% of PD patients, respectively; and 22.22% and 25.93% of stroke survivors, respectively. There was a significant correlation between depression and independence level in the entire group and between depression and marital status in stroke survivors. Conclusions: Although depression and anxiety are highly prevalent in patients with neurological conditions, the disorder has a very individual nature and is not associated with the patient’s age, duration of a condition or concomitant diseases. Screening for depression and anxiety as a part of comprehensive approach may increase treatment efficacy in neurological patients

The Risk of Depression and Anxiety in the Post-diagnostic Period of Multiple Sclerosis Measured by Screening Instruments and Structured Interviews

2017 ◽  
Vol 41 (S1) ◽  
pp. S236-S236 ◽  
Author(s):  
H. Hoang ◽  
E. Stenager ◽  
E. Stenager
Keyword(s):  
Multiple Sclerosis ◽  
Depression Scale ◽  
Structured Interview ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Screening Instruments ◽  
Hospital Anxiety ◽  
Structured Interviews ◽  
Clinical Screening ◽  
Competing Interest

ObjectiveTo examine the risk of depression and anxiety in MS patients in the post-diagnostic period by using clinical screening instruments and a diagnostic structured clinical interview.MethodA population of 134 MS patients was examined for the risk of depression and anxiety in the post-diagnostic period of MS using the clinical screening instruments Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale (HADS). Within six weeks of diagnosis, patients with cut-off > 12 for BDI and > 7 for HADS were offered a clinical structured interview using the Schedules for Clinical Assessment in Neuropsychiatry/SCAN Version 2.1.ResultsThe prevalence of depressive symptoms and depression in the post-diagnostic period of MS was 49.2% when using the screening instruments, but only 15.2% when using the SCAN interview. For anxiety, the prevalence was 3.4% for both the screening instruments and the SCAN interview in the post-diagnostic period of MS.ConclusionMS patients have a risk of depression and anxiety in the post-diagnostic period of MS, but it is crucial to consider which tools to use in a clinical setting to investigate depression and anxiety in MS patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Depression, anxiety and multiple sclerosis: Links with alexithymia

2011 ◽  
Vol 26 (S2) ◽  
pp. 1698-1698 ◽  
Author(s):  
J. Aloulou ◽  
C. Hachicha ◽  
R. Masmoudi ◽  
A. Boukhris ◽  
C. Mhiri ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mood State ◽  
Disease Onset ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Hospital Anxiety ◽  
Long Period ◽  
Prevalence Of Depression ◽  
Degree Of Disability

The aim of our study was to assess the prevalence of depression and anxiety in a population of patients treated for multiple sclerosis (MS) and their link with alexithymia.Method31 patients with MS according to McDonald's criteria, and followed in neurology department took part in the study. All patients were evaluated using a protocol to collect the epidemiological, clinical and evolution of the disease. We used versions of Arabized-Hospital Anxiety and Depression Scale (HADS) to assess the mood state and the Toronto Alexithymia Scale (TAS-20) for alexithymia.Results and commentsParticipants were divided on 18 women and 13 men with a mean age of 39 years. The prevalence of depression and anxiety were 42% and 52% respectively. The prevalence of alexithymia was 43%. The anxiety was correlated with the degree of disability and age of disease onset. Similarly, depression was more frequently observed in patients with higher EDSS, a long period of evolution. A positive correlation was found between alexithymia, depression and anxiety.Our study showed that half of all MS patients have mood disorders. However, depression is the most common and most disabling psychiatric disorder in MS. The place of anxiety should not be neglected because in case of comorbidity with depression, can be an aggravating factor. The frequency of alexitymia is high and appears to be positively correlated with depression and anxiety.

scholarly journals Validation of Mood Measures for People with Multiple Sclerosis

2014 ◽  
Vol 16 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Tessa M. Watson ◽  
Emma Ford ◽  
Esme Worthington ◽  
Nadina B. Lincoln
Keyword(s):  
Multiple Sclerosis ◽  
Depression Scale ◽  
High Sensitivity ◽  
High Specificity ◽  
Anxiety And Depression ◽  
Cutoff Score ◽  
Depression And Anxiety ◽  
Hospital Anxiety ◽  
Depression Subscale ◽  
Anxiety Subscale

Background: Valid assessments are needed in order to identify anxiety and depression in people with multiple sclerosis (MS). The objective of this study was to assess the validity of questionnaire measures of mood in people with MS. Methods: People with MS were recruited from a clinic database and asked to complete and return a questionnaire containing the Beck Anxiety Inventory (BAI), Beck Depression Inventory–II (BDI-II), and Hospital Anxiety and Depression Scale (HADS). Those who returned the questionnaire were invited to complete a structured clinical interview, which was blind to the results of the questionnaire. Results: The BDI-II and HADS were both found to be valid measures to detect depression and anxiety in people with MS. An optimum cutoff score of 23 for the BDI-II yielded high sensitivity (85%) and high specificity (76%). An optimum cutoff score of 11 for the HADS demonstrated high sensitivity and specificity for both the Anxiety subscale (sensitivity 90%, specificity 92%) and the Depression subscale (sensitivity 77%, specificity 81%). The BAI had high sensitivity (80%) but poor specificity (46%) for detecting anxiety. Conclusion: The BDI-II and HADS can be used to identify mood disorders in people with MS.

scholarly journals Prevalence of Depression and Anxiety Among Patients with Noncommunicable Diseases in The Kingdom of Bahrain

2018 ◽  
Vol 30 (3) ◽  
pp. 10-19
Keyword(s):  
Risk Factors ◽  
Mental Illness ◽  
Low Income ◽  
Depression Scale ◽  
Personal History ◽  
Noncommunicable Diseases ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Prevalence Of Depression ◽  
History Of

Background and objectives: There is a high coexistence between mental disorders and chronic noncommunicable diseases (NCD). Patients with chronic illnesses have higher rates of depression and anxiety when compared to the healthy individuals. The study aimed to estimate the prevalence of depression and anxiety and to explore the associated risk factors. Methods: A cross sectional study conducted in the NCD clinics of five health centers in the Kingdom of Bahrain included all patients attending these clinics from January 2016 to March 2016. Hospital anxiety and depression scale (HADS) was used to screen patients for depression and anxiety. Logistic regression analyses were used to identify risk factors associated with anxiety and depression. All the analyses were conducted using STATA 12; P < 0.05 was considered statistically significant. Results: A total of 456 patients were included in the study. Mild and moderate to severe type of depression were observed in 71 (15.6%) and 53 (11.6%) patients, respectively. According to the multivariable model, the odds of having high depression score was significantly higher in patients aged < 45 years (adjusted odds ratio (OR) = 2.01; P = 0.01), with low income (adjusted OR = 1.99; P = 0.02), with personal history of mental illness (adjusted OR = 5.13; P = 0.001), and with lower educational levels (P = 0.02). Mild and moderate to severe anxiety scores were observed in 55 (12.1%) and 34 (7.5%) patients, respectively. According to the multivariate model, the odds of having high anxiety score was significantly higher in females (adjusted OR = 2.85; P < 0.001), patients aged < 45 years (adjusted OR = 2.41; P = 0.005), in patients with low income (adjusted OR = 3.62; P < 0.001), and in those with personal history of mental illness (adjusted OR = 4.5; P = 0.004). Conclusion: There is a high prevalence of depression and anxiety among patients attending NCD clinics in the Kingdom of Bahrain. Therefore, screening of mental health diseases should be established.

scholarly journals Distractibility in multiple sclerosis: The role of depression

2016 ◽  
Vol 2 ◽  
pp. 205521731665315 ◽  
Author(s):  
Viral P Patel ◽  
Aaron Zambrana ◽  
Lisa AS Walker ◽  
Nathan Herrmann ◽  
Richard H Swartz ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Regression Analysis ◽  
Cognitive Assessment ◽  
Ecological Validity ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Hospital Anxiety ◽  
Impaired Performance

The present study assesses the influence of depression and anxiety on the effects of cognitive distracters in people with multiple sclerosis (MS). Participants completed computerized versions of the Symbol Digit Modalities Test (c-SDMT) with ( n = 51) and without ( n = 51) auditory distracters. Based on the Hospital Anxiety and Depression Scale (HADS), 29 (28.4%) and 51 (50%) participants were classified as depressed or anxious, respectively. A regression analysis revealed that depression ( p = 0.034), not anxiety ( p = 0.264), further impaired performance on the c-SDMT, particularly in the presence of distracters. These results suggest that distracter effects are influenced by depression more than anxiety. Given that distracters are ubiquitous in real-world environments, their use in a cognitive assessment adds to the ecological validity of the results.

In multiple sclerosis anxiety, not depression, is related to gender

2015 ◽  
Vol 22 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Marie Théaudin ◽  
Kristoffer Romero ◽  
Anthony Feinstein
Keyword(s):  
Multiple Sclerosis ◽  
General Population ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
High Prevalence ◽  
Psychiatric Sequelae ◽  
The Impact

Background: There is a high prevalence of depressive and anxiety disorders in multiple sclerosis (MS), a disease 2.5 times more frequent in females. Contrary to the general population, in whom studies have demonstrated higher rates of depression and anxiety in females, little is known about the impact of gender on psychiatric sequelae in MS patients. Objectives: We conducted a retrospective study to try to clarify this uncertainty. Methods: Demographic, illness-related and behavioral variables were obtained from a neuropsychiatric database of 896 patients with a confirmed diagnosis of MS. Symptoms of depression and anxiety were obtained with the Hospital Anxiety and Depression Scale (HADS). Gender comparisons were undertaken and predictors of depression and anxiety sought with a linear regression analysis. Results: HADS data were available for 711 of 896 (79.35%) patients. Notable gender differences included a higher frequency of primary progressive MS in males ( p = 0.002), higher HADS anxiety scores in females ( p < 0.001), but no differences in HADS depression scores. Conclusion: In MS, gender influences the frequency of anxiety only. This suggests that the etiological factors underpinning anxiety and depression in MS are not only different from one another, but also in the case of depression, different from those observed in general population samples.

scholarly journals The contribution of self-disclosure to the prediction of mood symptoms in patients with multiple sclerosis

2022 ◽  
Author(s):  
Marzieh Mahboobi ◽  
Abbas Khashandish ◽  
Abdorreza Naser Moghadasi ◽  
Mohammad Ali Sahraian ◽  
Maryam Bahrami-Hidaji ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Empirical Support ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Positive Role ◽  
Self Disclosure ◽  
The Impact ◽  
Distress Disclosure

Background: Depression and anxiety are the most prevalent psychological symptoms in patients with multiple sclerosis (MS) and have a significant impact on quality of life (QOL) and disability progression in the patients. Therefore, it is very important to find ways to reduce the impact of these disorders on patients with MS. The data suggest that self-disclosure may be beneficial in improving symptoms of depression and anxiety in many chronic diseases. Due to the scarcity of related studies, this cross-sectional research aimed to evaluate the relations between self-disclosure, anxiety, and depression in patients with MS. Methods: 112 patients with MS from several referral outpatient MS clinics participated in the study. Data were extracted using socio-demographic questionnaire to determine clinical variables and patient characteristics, Distress Disclosure Index (DDI) to assess self-disclosure, Hospital Anxiety and Depression Scale (HADS) to evaluate mood states, and Kurtzke Expanded Disability Status Scale (EDSS) recorded by an experienced neurologist. Results: Multiple linear regression analysis with controlling disease variables demonstrated distress disclosure as an independent factor to predict anxiety and depression in the patients (P < 0.05). Results also presented a significant, positive relationship between hospitalization history and disability levels with anxiety and depression. These findings clearly state that these two variables can accurately predict a heightened state of anxiety and depression in patients with MS. Conclusion: This study provides empirical support for the positive role of disclosure in decreasing the negative emotions in MS. Further studies are needed to clarify the effects of disclosing MS in different cultural and situational contexts.

scholarly journals Prevalence of and Factors Associated with Depression and Anxiety in Brazilian Medical Students

2020 ◽  
Vol 44 (1) ◽  
Author(s):  
Christiane Fernandes Ribeiro ◽  
Carolina Martins Cabrita Lemos ◽  
Nina Nogueira Alt ◽  
Rulliany Lizia Tinoco Marins ◽  
Weydler Campos Hottz Corbiceiro ◽  
...  
Keyword(s):  
Mental Health ◽  
Medical Students ◽  
Mental Disorders ◽  
Associated Factors ◽  
Psychiatric Treatment ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Factors Associated ◽  
History Of

Abstract: Introduction: Although mental health is an essential condition for the human development, the scientific literature shows a high frequency of depression and anxiety in university students, mainly among medical students. To contribute to a better understanding concerning medical students’ mental health, this study had the following objectives: (a) to estimate the prevalence of indicative scores for anxiety, depression, and for simultaneous anxiety and depression, and (b) to analyze factors associated with these conditions in medical students at a federal university in Brazil. Methods: This is a cross-sectional study including students from a federal medical school in the state of Rio de Janeiro. Participants were enrolled during the first semester of 2015. Mental disorders were assessed with Hospital Anxiety and Depression Scale (HADS). The magnitude of mental disorders and its associated factors were analyzed calculating prevalence rates and unadjusted and adjusted prevalence ratios (PR) and 95% confidence intervals (95% CI). Results: We analyzed 355 students. Anxiety was the most common condition (41.4%), followed by depression (8.2%), and both anxiety and depression simultaneously (7.0%). After adjustment of multivariate models and considering both gender and age as confounding variables, our results showed a differentiated risk pattern in relation to three outcomes analyzed. Anxiety risk increased with ‘feeling alone’ (adjusted PR: 1.59; 95% CI: 1.123; 2.259), ‘having a history of psychological and/or psychiatric treatment before entering university’ (adjusted PR: 1.63; 95% CI: 1.052; 2.542), and ‘feeling morally harmed at college’ (adjusted PR: 1.66; (95% CI: 1.168; 2.364). Depression risk increased with ‘feeling alone’ (adjusted PR: 6.84; 95% CI: 2.047; 22.894) and ‘having a history of psychological and/or psychiatric treatment before entering university’ (adjusted PR: 4.74; 95% CI: 1.790; 12.579). Simultaneous anxiety and depression were associated with ‘feeling alone’ (adjusted PR: 8.90; 95%CI: 2.075; 38.208) and ‘having a history of psychological and/or psychiatric treatment during the medical course (adjusted PR: 3.16; 95% CI: 1.061; 9.439) and before (adjusted PR: 6.01; 95% CI: 2.000; 18.098) entering university’. Conclusion: Anxiety and depression are common conditions in medical students. The main associated factors were therapies for mental health before entering in university, loneliness and lack of respect in interpersonal relationships during the medical course. Therefore, initiatives aiming at better welcoming students and reducing conflicting situations can help minimizing these mental problems during university career, once they have a large impact not only in their quality of life, but also in the way they will deal with their patients in the future.

Effect of integrated Yoga and Physical therapy on audiovisual reaction time, anxiety and depression in patients with chronic multiple sclerosis: a pilot study

2016 ◽  
Vol 13 (3) ◽  
Author(s):  
Shivaji Chobe ◽  
Hemant Bhargav ◽  
Nagarathna Raghuram ◽  
Christoph Garner
Keyword(s):  
Multiple Sclerosis ◽  
Reaction Time ◽  
Physical Therapy ◽  
Psychological Health ◽  
Depression Scale ◽  
Reaction Times ◽  
Sufficient Evidence ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Visual Reaction

Abstract: Multiple sclerosis (MS) is characterized by a significant deterioration in auditory and visual reaction times along with associated depression and anxiety. Yoga and Physical therapy (PT) interventions have been found to enhance recovery from these problems in various neuropsychiatric illnesses, but sufficient evidence is lacking in chronic MS population. The aim of this study was to assess the effect of integrated Yoga and Physical therapy (IYP) on audiovisual reaction times, depression and anxiety in patients suffering from chronic MS.: From a neuro-rehabilitation center in Germany, 11 patients (six females) suffering from MS for 19±7.4 years were recruited. Subjects were in the age range of 55.45±10.02 years and had Extended Disability Status Scores (EDSS) below 7. All the subjects received mind–body intervention of integrated Yoga and Physical therapy (IYP) for 3 weeks. The intervention was given in a residential setup. Patients followed a routine involving Yogic physical postures, pranayama, and meditations along with various Physical therapy (PT) techniques for 21 days, 5 days a week, 5 h/day. They were assessed before and after intervention for changes in audiovisual reaction times (using Brain Fit Model No. OT 400), anxiety, and depression [using Hospital Anxiety and Depression Scale (HADS)]. Data was analyzed using paired samples test.: There was significant improvement in visual reaction time (p=0.01), depression (p=0.04), and anxiety (p=0.02) scores at the end of 3 weeks as compared to the baseline. Auditory reaction time showed reduction with borderline statistical significance (p=0.058).: This pilot project suggests utility of IYP intervention for improving audiovisual reaction times and psychological health in chronic MS patients. In future, randomized controlled trials with larger sample size should be performed to confirm these findings.

scholarly journals Depression, anxiety and blood serotonin in patients with multiple sclerosis during Betaferon treatment

2008 ◽  
Vol 7 (5-2) ◽  
pp. 424-427
Author(s):  
T. N. Trushnikova ◽  
T. V. Bajdina
Keyword(s):  
Multiple Sclerosis ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Hospital Anxiety ◽  
Immunomodulating Therapy ◽  
Blood Serotonin ◽  
Immunoenzyme Analysis ◽  
Multiple Sclerosis Patients

Depression and anxiety were examined by Hospital Anxiety and Depression Scale and Spilberger Scale in 217 multiple sclerosis patients treated by Betaferon. The concentration of blood serotonin was determined by immunoenzyme analysis in 71 of them. The multiple sclerosis patients had progressive high levels of depression ((7,55 ± 3,61) points; р = 0,000) and anxiety ((7,55 ± 3,61) points; р = 0,000), and the decreased blood serotonin concentration ((210 ± 134,2) versus (269 ± 98,8) ng/ml; р = 0,036 in healthy people). The level of anxiety was related to the level of serotonin depression. Betaferon did not correct the affective disorders in multiple sclerosis patients, except the decreasing the degree of anxiety, and did not normalize the level of blood serotonin, that suggest the use of selective serotonin reuptake inhibitors during immunomodulating therapy.

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