In multiple sclerosis anxiety, not depression, is related to gender

2015 ◽  
Vol 22 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Marie Théaudin ◽  
Kristoffer Romero ◽  
Anthony Feinstein
Keyword(s):  
Multiple Sclerosis ◽  
General Population ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
High Prevalence ◽  
Psychiatric Sequelae ◽  
The Impact

Background: There is a high prevalence of depressive and anxiety disorders in multiple sclerosis (MS), a disease 2.5 times more frequent in females. Contrary to the general population, in whom studies have demonstrated higher rates of depression and anxiety in females, little is known about the impact of gender on psychiatric sequelae in MS patients. Objectives: We conducted a retrospective study to try to clarify this uncertainty. Methods: Demographic, illness-related and behavioral variables were obtained from a neuropsychiatric database of 896 patients with a confirmed diagnosis of MS. Symptoms of depression and anxiety were obtained with the Hospital Anxiety and Depression Scale (HADS). Gender comparisons were undertaken and predictors of depression and anxiety sought with a linear regression analysis. Results: HADS data were available for 711 of 896 (79.35%) patients. Notable gender differences included a higher frequency of primary progressive MS in males ( p = 0.002), higher HADS anxiety scores in females ( p < 0.001), but no differences in HADS depression scores. Conclusion: In MS, gender influences the frequency of anxiety only. This suggests that the etiological factors underpinning anxiety and depression in MS are not only different from one another, but also in the case of depression, different from those observed in general population samples.

scholarly journals The contribution of self-disclosure to the prediction of mood symptoms in patients with multiple sclerosis

2022 ◽  
Author(s):  
Marzieh Mahboobi ◽  
Abbas Khashandish ◽  
Abdorreza Naser Moghadasi ◽  
Mohammad Ali Sahraian ◽  
Maryam Bahrami-Hidaji ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Empirical Support ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Positive Role ◽  
Self Disclosure ◽  
The Impact ◽  
Distress Disclosure

Background: Depression and anxiety are the most prevalent psychological symptoms in patients with multiple sclerosis (MS) and have a significant impact on quality of life (QOL) and disability progression in the patients. Therefore, it is very important to find ways to reduce the impact of these disorders on patients with MS. The data suggest that self-disclosure may be beneficial in improving symptoms of depression and anxiety in many chronic diseases. Due to the scarcity of related studies, this cross-sectional research aimed to evaluate the relations between self-disclosure, anxiety, and depression in patients with MS. Methods: 112 patients with MS from several referral outpatient MS clinics participated in the study. Data were extracted using socio-demographic questionnaire to determine clinical variables and patient characteristics, Distress Disclosure Index (DDI) to assess self-disclosure, Hospital Anxiety and Depression Scale (HADS) to evaluate mood states, and Kurtzke Expanded Disability Status Scale (EDSS) recorded by an experienced neurologist. Results: Multiple linear regression analysis with controlling disease variables demonstrated distress disclosure as an independent factor to predict anxiety and depression in the patients (P < 0.05). Results also presented a significant, positive relationship between hospitalization history and disability levels with anxiety and depression. These findings clearly state that these two variables can accurately predict a heightened state of anxiety and depression in patients with MS. Conclusion: This study provides empirical support for the positive role of disclosure in decreasing the negative emotions in MS. Further studies are needed to clarify the effects of disclosing MS in different cultural and situational contexts.

scholarly journals Sleep patterns and symptoms of anxiety and depression in patients with chronic pain

2009 ◽  
Vol 67 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Martha M.C. Castro ◽  
Carla Daltro
Keyword(s):  
Chronic Pain ◽  
Sleep Disturbances ◽  
Myofascial Pain ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Sleep Patterns ◽  
Symptoms Of Depression ◽  
High Prevalence ◽  
The Mean

BACKGROUND: Sleep disturbances and symptoms of anxiety and depression have been shown to be involved in the genesis and perpetuation of chronic pain. OBJECTIVE: To evaluate sleep patterns and the prevalence of symptoms of anxiety and depression in patients with chronic pain. METHOD: Four hundred consecutive patients referred to a chronic pain outpatient clinic were investigated using patient charts, the numerical Visual Analogue Scale for the evaluation of pain, the Hospital Anxiety and Depression scale and the Mini-Sleep Questionnaire. RESULTS: The mean age of patients was 45.6±11.4 years. The most frequent medical diagnosis was myofascial pain followed by neuropathic pain. The prevalence of symptoms of anxiety was 72.8%, depression 93% and altered sleep patterns 93%. CONCLUSION: This study revealed a high prevalence of symptoms of depression and anxiety and alterations in sleep patterns in patients with chronic pain, justifying investigation into these disturbances in this group of patients.

Changes in anxiety and depression symptoms associated to the outcome of MOH: A post-hoc analysis of the Comoestas Project

Cephalalgia ◽  
2017 ◽  
Vol 38 (4) ◽  
pp. 646-654 ◽  
Author(s):  
Sara Bottiroli ◽  
Marta Allena ◽  
Grazia Sances ◽  
Roberto De Icco ◽  
Micol Avenali ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Affective State ◽  
Antidepressant Drugs ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
Number Of Patients ◽  
The Impact

Aims To evaluate the impact of treatment success on depression and anxiety symptoms in medication-overuse headache (MOH) and whether depression and anxiety can be predictors of treatment outcome. Methods All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion over a six-month period. Depression and anxiety were assessed using the Hospital Anxiety and Depression Scale. Results A total of 663 MOH patients were evaluated, and 492 completed the entire protocol. Of these, 287 ceased overuse and reverted to an episodic pattern (responders) and 23 relapsed into overuse. At the final evaluation, the number of patients with depressive symptoms was reduced by 63.2% among responders ( p < 0.001) and did not change in relapsers ( p = 0.13). Anxious symptomatology was reduced by 43.1% in responders ( ps < 0.001) and did not change in relapsers ( p = 0.69). At the multivariate analysis, intake of a prophylactic drug and absence of symptoms of depression at six months emerged as prognostic factors for being a responder (OR 2.406; p = 0.002 and OR 1.989; p = 0.019 respectively), while lack of antidepressant drugs and presence of symptoms of depression at six months were prognostic factors for relapse into overuse (OR 3.745; p = 0.004 and OR 3.439; p = 0.031 respectively). Conclusions Symptomatology referred to affective state and anxiety can be significantly reduced by the treatment of MOH. Baseline levels of depression and anxiety do not generally predict the outcome at six months. Their persistence may represent a trait of patients with a negative outcome, rather than the consequence of a treatment failure.

scholarly journals THE EARLY BIRD GETS THE WORM, NOT ANXIETY OR DEPRESSION: HOW INSOMNIA SYMPTOMS PREDICT ANXIETY AND DEPRESSION

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S45-S45
Author(s):  
Courtney J Bolstad ◽  
Anisha L Thomas ◽  
Michael R Nadorff
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Anxiety Symptoms ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Regression Analyses ◽  
Symptoms Of Depression ◽  
Early Bird ◽  
The Impact ◽  
Insomnia Symptoms

Abstract Symptoms of insomnia are associated with symptoms of depression and anxiety in older adults, yet less is known about the impact of specific forms of insomnia (i.e. onset, maintenance, and terminal insomnia). We explored how insomnia type predicted symptoms of anxiety and depression in older adults (n = 133; mean age 69, range 65-89). We hypothesized that onset and maintenance insomnia would have stronger relations to depression and anxiety than terminal insomnia. Regression analyses indicated that onset insomnia was the only significant predictor of anxiety symptoms, and maintenance was the only significant predictor of depressive symptoms. Thus, our findings suggest that despite overlap between depression and anxiety, insomnia may have different mechanisms of affecting each disorder. Implications for the treatment of anxiety and depressive symptoms by addressing insomnia problems will be discussed.

Implications of violence experience in postpartum depression

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
D Fraga ◽  
F Marabotti ◽  
Costa Leite ◽  
R de Cássia ◽  
Duarte Lima ◽  
...  
Keyword(s):  
Postpartum Depression ◽  
Depression Scale ◽  
Maternity Hospital ◽  
Intimate Partner ◽  
World Health ◽  
Cross Sectional ◽  
Female Population ◽  
Symptoms Of Depression ◽  
High Prevalence ◽  
The Impact

Abstract Introduction The violence against women is an exacerbating factor in public health that affects a third of the world's female population, and the intimate partner is the main perpetrator. Researches show the impact of violence in the victims' health, such as: postpartum depression (PPD). In this context, considering the importance and magnitude of the experience of violence and its impact on health, as well as depression negatively impacted on the health of the mother and baby, justify it to carry out this study. Objective To identify the prevalence of symptoms of PPD among puerperal women and to examine the association with violence experience. Methods This is a cross-sectional study, performed with 330 puerperal women admitted to a municipal maternity hospital in Cariacica - State of Espírito Santo, Brazil. Data collection was conducted by duly trained interviewers, using a form containing data on socioeconomic, behavioral and clinical characterization. In order to track violence acts, in life and in pregnancy, practiced by the intimate partner, we applied the World Health Organization instrument, which enables the identification of psychological, physical and sexual violence acts. The identification of the outcome under study, postpartum depression, was obtained by means of the Edinburgh Postnatal Depression Scale. The data collected were analyzed through the Stata 13.0 program, where the following tests were performed: Pearson chi-squared test and Poisson regression. Results a rate of 36.7% of participants (95% CI: 31.6-42.0) showed symptoms of postpartum depression. Women who experienced violence from their partners throughout their lives had 1.9 times more prevalence of symptoms of depression. Those who experienced aggression during pregnancy showed an increase of 38.0% of this illness (p = 0.037). Conclusions The data presented reveal the high prevalence of women with symptoms of PPD and that violence experience was associated with higher frequencies of this event. Key messages Women who experienced violence from their partners throughout their lives had 1.9 times more prevalence of symptoms of depression. The data presented reveal the high prevalence of women with symptoms of postpartum depression and that violence experience was associated with higher frequencies of this event.

scholarly journals Assessing the Predictor Roles of Mindfulness and Spiritual Intelligence for Depressive and Anxiety Symptoms

2020 ◽  
Vol 5 (3) ◽  
pp. 273-285
Author(s):  
Pınar Ünal-Aydın ◽  
Yasin Arslan ◽  
Orkun Aydın
Keyword(s):  
Short Form ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Spiritual Intelligence ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Five Facet Mindfulness Questionnaire ◽  
Hospital Anxiety ◽  
Web Based ◽  
Predictors Of Depression

The goal of this study was to examine the effects of mindfulness (MF) and spiritual intelligence (SI) as predictors of depression and anxiety, the most frequent manifestations of mental disorders – among 184 Turkish participants of diverse ages, predominantly students, living in Istanbul and Sarajevo. Four instruments were administered either directly or via web-based services: Scale for Spiritual Intelligence (SSI), Hospital anxiety and depression scale (HADS), Five Facet Mindfulness Questionnaire – Short Form (FFMQ-S) and Sociodemographic Information Form. Through the use of linear regression analysis, Actaware (b=-.19, p≤.001), Nonjudge (b=-.22, p≤.001), Nonreact (b=-.19, p≤.001) subscales of FFMQ-S were found to be negative predictors for depression and anxiety, whereas, Self-understanding subscale of SSI was not significant. Although our findings suggest that spiritual intelligence is not significant in prediction of depression and anxiety, our research provides empirical evidence for the link between MF, SI, depression and anxiety, as well as revealing MF as predictor for anxiety and depression which may be useful for further improvements in the scope of current interventions.

Discontinuing cannabis improves depression in people with multiple sclerosis: A short report

2020 ◽  
pp. 135245852093407 ◽  
Author(s):  
Anthony Feinstein ◽  
Cecilia Meza ◽  
Cristiana Stefan ◽  
W Richard Staines
Keyword(s):  
Multiple Sclerosis ◽  
Depression Scale ◽  
Cannabis Use ◽  
Anxiety And Depression ◽  
Cognitively Impaired ◽  
Short Report ◽  
Hospital Anxiety ◽  
Symptoms Of Depression ◽  
Cannabis Withdrawal ◽  
Depression Change

To assess whether symptoms of depression change when people with multiple sclerosis (pwMS) discontinue cannabis use, 40 cognitively impaired pwMS who smoked cannabis almost daily were randomly assigned to either a cannabis continuation (CC) or cannabis withdrawal (CW) group. Both groups were followed for 28 days. All participants completed the Hospital Anxiety and Depression Scale. At day 28 the 11-nor-9-carboxy-Δ9-tetrahydro-cannabinol (THCCOOH)/creatinine ratio in the CW group declined to zero ( p = 0.0001), but remained unchanged in the CC group ( p = 0.709). Depression scores in those pwMS who were using cannabis to manage their depression remained statistically unchanged in the CC group, but declined in the CW group ( p = 0.006). Despite pwMS using cannabis to help their mood, depression improved significantly off the drug. Our finding provides a cautionary note in relation to cannabis use in pwMS, at least with respect to depression.

The Risk of Depression and Anxiety in the Post-diagnostic Period of Multiple Sclerosis Measured by Screening Instruments and Structured Interviews

2017 ◽  
Vol 41 (S1) ◽  
pp. S236-S236 ◽  
Author(s):  
H. Hoang ◽  
E. Stenager ◽  
E. Stenager
Keyword(s):  
Multiple Sclerosis ◽  
Depression Scale ◽  
Structured Interview ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Screening Instruments ◽  
Hospital Anxiety ◽  
Structured Interviews ◽  
Clinical Screening ◽  
Competing Interest

ObjectiveTo examine the risk of depression and anxiety in MS patients in the post-diagnostic period by using clinical screening instruments and a diagnostic structured clinical interview.MethodA population of 134 MS patients was examined for the risk of depression and anxiety in the post-diagnostic period of MS using the clinical screening instruments Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale (HADS). Within six weeks of diagnosis, patients with cut-off > 12 for BDI and > 7 for HADS were offered a clinical structured interview using the Schedules for Clinical Assessment in Neuropsychiatry/SCAN Version 2.1.ResultsThe prevalence of depressive symptoms and depression in the post-diagnostic period of MS was 49.2% when using the screening instruments, but only 15.2% when using the SCAN interview. For anxiety, the prevalence was 3.4% for both the screening instruments and the SCAN interview in the post-diagnostic period of MS.ConclusionMS patients have a risk of depression and anxiety in the post-diagnostic period of MS, but it is crucial to consider which tools to use in a clinical setting to investigate depression and anxiety in MS patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The relationship between fatigue and other clinical features of multiple sclerosis

2010 ◽  
Vol 17 (5) ◽  
pp. 604-612 ◽  
Author(s):  
Roger J Mills ◽  
Carolyn A Young
Keyword(s):  
Multiple Sclerosis ◽  
Depression Scale ◽  
Measurement Model ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Measurement Tool ◽  
Related Factors ◽  
Cross Sectional ◽  
Complex Relation ◽  
The Impact

Background: There has been considerable debate regarding the precise relationships between fatigue in multiple sclerosis (MS) and disease-related factors, such as disability, sleep disturbance, depression, age and sex. Existing studies give conflicting information. Objective: To clarify such relationships in a large cross-sectional study, using a rigorously developed measurement tool which was based on a clear definition of fatigue. Method: A pack containing the Neurological Fatigue Index for MS Summary Scale, the Hospital Anxiety and Depression Scale, the Epworth Sleepiness Scale, the Multiple Sclerosis Impact Scale and questions regarding sleep and demographics was mailed to patients with MS attending two centres in the UK. All scale scores were converted to parametric measures using the Rasch measurement model. Both linear and non-linear relationships were sought. Results: Data from 635 respondents (52% response) were analysed. Fatigue was strongly related to the impact of MS. Fatigue was worse in those with progressive disease and clearly worsened once ambulation was affected. There was only weak correlation with anxiety and depression. Fatigue was not related to disease duration or patient age. There was an intimate but complex relation between fatigue and sleep. Fatigue levels were minimum at a nocturnal sleep duration of 7.5 h. Conclusion: Clear relationships were found between fatigue and disability, disease type and sleep. Further physiological enquiry and trials of drug treatment and sleep modulation might be guided by these clinical relationships.

scholarly journals Affective Disorder and Functional Status as well as Selected Sociodemographic Characteristics in Patients with Multiple Sclerosis, Parkinson’s Disease and History of Stroke

Medicina ◽  
2020 ◽  
Vol 56 (3) ◽  
pp. 117 ◽  
Author(s):  
Andrzej Knapik ◽  
Ewa Krzystanek ◽  
Justyna Szefler–Derela ◽  
Joanna Siuda ◽  
Jerzy Rottermund ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Status ◽  
Affective Disorders ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Sociodemographic Characteristics ◽  
Stroke Survivors ◽  
Depression And Anxiety ◽  
Diagnostic Threshold ◽  
History Of

The main arguments in support of researching anxiety and depression in patients with chronic somatic diseases are the prevalence of affective disorders in the population, somatic conditions as risk factors of affective disorders and the search for effective preventative and therapeutic strategies. The aim of the study was to determine the association between the functional status, selected sociodemographic characteristics and prevalence as well as severity of anxiety and depression in patients with multiple sclerosis (MS), Parkinson’s disease (PD) and history of stroke (S). Material and methods: Eighty participants (44 women and 36 men) with MS (n = 22), PD (n = 31) and history of stroke (n = 27) were enrolled. All participants completed a questionnaire consisting of metrics, the Katz Index of Independence in Activities of Daily Living and the Hospital Anxiety and Depression Scale (HADS). Results: Fifty-five per cent of all participants did not present with anxiety or depression, 20% scored above the diagnostic threshold on the anxiety scale and 26% scored above the diagnostic threshold on the depression scale. Subgroup analysis revealed that anxiety and depression sufferers were 13.64% and 13.64% of MS patients, respectively; 22.58% and 35.48% of PD patients, respectively; and 22.22% and 25.93% of stroke survivors, respectively. There was a significant correlation between depression and independence level in the entire group and between depression and marital status in stroke survivors. Conclusions: Although depression and anxiety are highly prevalent in patients with neurological conditions, the disorder has a very individual nature and is not associated with the patient’s age, duration of a condition or concomitant diseases. Screening for depression and anxiety as a part of comprehensive approach may increase treatment efficacy in neurological patients

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