scholarly journals Novel Electrochemical Sensor Fabricated for Individual and Simultaneous Ultrasensitive Determination of Olaquindox and Carbadox Based on MWCNT-OH/CMK-8 Hybrid Nanocomposite Film

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3041 ◽  
Author(s):  
Yanqing Liu ◽  
Gengxin Hu ◽  
Hongwu Wang ◽  
Su Yao ◽  
Yinjian Ye
Keyword(s):  
Electrochemical Sensor ◽  
Simultaneous Determination ◽  
Modified Electrode ◽  
Electrochemical Impedance ◽  
Modified Electrodes ◽  
Differential Pulse ◽  
Hybrid Nanocomposite ◽  
Experimental Conditions ◽  
Linear Relationships

A hybrid nanocomposite consisting of hydroxylated multi-walled carbon nanotubes (MWCNTs−OH) and cube mesoporous carbon (CMK−8) was applied in this study to construct an MWCNT−OH/CMK−8/gold electrode (GE) electrochemical sensor and simultaneously perform the electro-reduction of olaquindox (OLA) and carbadox (CBX). The respective peak currents of CBX and OLA on the modified electrode increased by 720- and 595-fold relative to the peak current of GE. The performances of the modified electrode were investigated with electrochemical impedance spectroscopy, cyclic voltammetry, and differential pulse voltammetry. Then, the modified electrodes were used for the individual and simultaneous determination of OLA and CBX. The fabricated sensor demonstrated a linear response at 0.2–500 nmol/L in optimum experimental conditions, and the detection limits were 104.1 and 62.9 pmol/L for the simultaneous determination of OLA and CBX, respectively. As for individual determination, wide linear relationships were obtained for the detected OLA with levels of 0.05–500 nmol/L with LOD of 20.7 pmol/L and the detected CBX with levels of 0.10–500 nmol/L with LOD of 50.2 pmol/L. The fabricated sensor was successfully used in the independent and simultaneous determination of OLA and CBX in spiked pork samples.

scholarly journals An Electrochemical Sensor Based On Graphite Electrode Modified With Silica Containing 1-N-Propyl-3-Methylimidazolium Species For Determination Of Ascorbic Acid

2019 ◽  
Vol Vol. 14, No.1 ◽  
pp. 5-14 ◽  
Author(s):  
Anastasiya Tkachenko ◽  
Mykyta Onizhuk ◽  
Oleg Tkachenko ◽  
Leliz T. Arenas ◽  
Edilson V. Benvenutt ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Cyclic Voltammetry ◽  
Electrochemical Sensor ◽  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Pharmaceutical Formulations ◽  
Differential Pulse ◽  
Long Term Stability ◽  
Diffusion Limited

In the present study, an electrochemical sensor based on the electrode (SiMImCl/C) consisting of graphite and silica, grafted with 1-n-propyl-3-methylimidazolium chloride was used for ascorbic acid (AA) quantification in pharmaceuticals and food formulations. Cyclic voltammetry and electrochemical impedance spectroscopy were applied for electrochemical characterization of the SiMImCl/C electrode. The cyclic voltammetry study revealed that the oxidation of AA on this electrode is an irreversible process, realized by adsorption and diffusion limited step. The differential pulse voltammetry was applied to develop a procedure for the AA determination. The linear range was found to be 0.3–170 μmol L-1 and the limit of detection – 0.1 μmol L-1. The proposed SiMImCl/C electrode has long term stability and does not show electrochemical activity towards the analytes, which commonly coexist with AA. The sensor was successfully used for quantification of AA in food and pharmaceutical formulations.

scholarly journals Simultaneous electrochemical determination of acetaminophen and metoclopramide at electrochemically pre-treated disposable graphite pencil electrode

2016 ◽  
Vol 6 (3) ◽  
pp. 265 ◽  
Author(s):  
Shreekant M Patil ◽  
Vijay P Pattar ◽  
Sharanappa T Nandibewoor
Keyword(s):  
Simultaneous Determination ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Experimental Conditions ◽  
Positive Direction ◽  
Oxidation Potentials ◽  
Voltammetric Behavior ◽  
Pulse Voltammetry ◽  
Apparent Shift

<p class="PaperAbstract"><span lang="EN-US">A sensitive and economic voltammetric method was developed for the simultaneous determination of acetaminophen (AMP) and metoclopramide (MCP) using pre-treated graphite pencil electrode (PTGPE). Compared to a graphite pencil electrode, the pre-treated electrode showed an apparent shift of the oxidation potentials in the positive direction and a notable enhancement in the current responses for both AMP and MCP. Cyclic voltammetry (CV) was used to study the voltammetric behavior of the drugs, while differential pulse voltammetry (DPV) was used to determine AMP and MCP simulta­neously. The dependence of the current on scan rate, pH and concentration was investi­gated to boost the experimental conditions for simultaneous determination. The calibra­tion curves were obtained over the range of 0.1</span><span lang="EN-US">×</span><span lang="EN-US">10<sup>-7</sup> to 1.1</span><span lang="EN-US">×</span><span lang="EN-US">10<sup>-7</sup> M, the concentration of each of both the drugs was varied by keeping the other constant, and achieved lower detection limit of 3.25 nM for AMP and 1.16 nM for MCP. The developed method was found to be selective and rapid for the simultaneous determination of AMP and MCP. The proposed method was applied simultaneously in real samples and pharmaceutical samples, with satisfactory results.</span></p>

scholarly journals Highly Sensitive Detection of Dopamine at Ionic Liquid Functionalized RGO/ZIF-8 Nanocomposite-Modified Electrode

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Lei Cheng ◽  
Youjun Fan ◽  
Xingcan Shen ◽  
Hong Liang
Keyword(s):  
Ionic Liquid ◽  
Modified Electrode ◽  
Electrocatalytic Activity ◽  
Electrochemical Impedance ◽  
Modified Electrodes ◽  
Differential Pulse ◽  
Zeolitic Imidazolate Framework ◽  
Response Range ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A hybrid and hierarchical nanocomposite was successfully prepared by the growth of zeolitic imidazolate framework-8 (ZIF-8) on the template of ionic liquid (IL, [Bmim][BF4]) functionalized reduced graphene oxide (IL-RGO). The structure and morphology of the IL-RGO/ZIF-8 nanocomposite were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectrometer (FTIR), and Raman spectroscopy. The results showed that RGO sheets were refrained from restacking by IL, and ZIF-8 nanoparticles grew well on the surface of IL-RGO. Owing to the synergistic effect from large surface area and excellent electrocatalytic activity of ZIF-8 and great electrical conductivity of IL-RGO, a highly sensitive sensor for dopamine (DA) can be obtained. IL-RGO/ZIF-8-modified electrode exhibits good electrocatalytic activity and electroconductive properties towards DA which were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Compared with bare or IL-RGO-modified electrodes, the IL-RGO/ZIF-8-modified electrode effectively depressed the oxidation overpotential of DA. The linear response range of DA was from 1.0×10−7 to 1.0×10−4 mol/L with a low detection of limit 3.5×10−8 mol/L. In addition, the sensor was shown to provide satisfactory stability for the determination of DA.

NiFe2O4nanoparticles decorated with MWCNTs as a selective and sensitive electrochemical sensor for the determination of epinephrine using differential pulse voltammetry

2014 ◽  
Vol 6 (17) ◽  
pp. 6885-6892 ◽  
Author(s):  
Ali A. Ensafi ◽  
F. Saeid ◽  
B. Rezaei ◽  
Ali R. Allafchian
Keyword(s):  
Electrochemical Sensor ◽  
Differential Pulse Voltammetry ◽  
Modified Electrode ◽  
Electrochemical Method ◽  
Differential Pulse ◽  
Synergic Effect ◽  
Pulse Voltammetry

A new electrochemical method was developed for epinephrine detection based on NiFe2O4–MWCNT-modified electrode. The nanocomposite has a synergic effect on the oxidation of epinephrine.

scholarly journals Preparation and Application of Keggin Silicomolybdic acid Modified Electrode

2020 ◽  
Author(s):  
Miao Liu ◽  
Mingxuan Jia ◽  
Dong Hui Li
Keyword(s):  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Photoelectron Spectroscopy ◽  
Limit Of Detection ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
X Ray ◽  
Linear Relationships

Abstract An innovative method for the determination of isoniazid tablets is studied through electrochemical method for the modification of glassy carbon electrode (GCE). Polyoxomolybdate, with stable structures, has not been widely used for the determination of substance. In this study, the mentioned polyoxomolybdate was characterized by Fourier transform infrared spectroscopy (FT-IR), UV-vis, X-ray diffraction (XRD), Atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS), and used to modify the glassy carbon electrode. The electrochemical performance of the polyoxomolybdate@GCE was investigated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV), compared with the unmodified electrode, the proposed polyoxomolybdate modified electrode exhibited strong electro-catalytic activities towards isoniazid (INH). Under the optimized conditions, there was linear relationships between the DPV peak currents and the concentrations in the range of 1 × 10 -7 g/L to 3 × 10 -7 g/L for INH (R 2 = 0.9979), with the limit of detection (LOD) of 0.024 μg/L (based on S/N = 3). The modified electrode has proper reproducibility (RSD < 5%), stability, response time (< 3 min) and lifetime (up to 6 days).

scholarly journals A hybrid nanocomposite of CeO2–ZnO–chitosan as an enhanced sensing platform for highly sensitive voltammetric determination of paracetamol and its degradation product p-aminophenol

RSC Advances ◽  
2019 ◽  
Vol 9 (28) ◽  
pp. 15986-15996 ◽  
Author(s):  
Noor B. Almandil ◽  
Mohamed Ibrahim ◽  
Hossieny Ibrahim ◽  
Abdel-Nasser Kawde ◽  
Ibrahim Shehatta ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Modified Electrode ◽  
Degradation Product ◽  
Pharmaceutical Formulations ◽  
Voltammetric Determination ◽  
Hybrid Nanocomposite ◽  
Sensing Platform ◽  
Highly Sensitive

A highly selective electrochemical sensor was fabricated based on CeO2–ZnO–chitosan hybrid nanocomposite modified electrode and was successfully applied for the determination of PAR in pharmaceutical formulations.

scholarly journals Preparation of Electrochemical Sensor Based on Zinc Oxide Nanoparticles for Simultaneous Determination of AA, DA, and UA

2020 ◽  
Vol 8 ◽  
Author(s):  
Yuanzhi Pan ◽  
Junli Zuo ◽  
Zhongyu Hou ◽  
Yizhong Huang ◽  
Cancan Huang
Keyword(s):  
Electrochemical Sensor ◽  
Simultaneous Determination ◽  
Modified Electrode ◽  
Zinc Oxide Nanoparticles ◽  
Clinical Applications ◽  
X Ray Diffraction ◽  
Modified Glassy Carbon Electrode ◽  
Zno Nps ◽  
X Ray

ZnO nanoparticles (NPs) were synthesized using a hydrothermal method. Scanning electron microscope (SEM) and X-ray diffraction have been used for characterizing the synthesized ZnO NPs. An electrochemical sensor was fabricated using ZnO NPs–modified glassy carbon electrode for simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). The proposed electrochemical sensor exhibited excellent detection performance toward three analytes, demonstrating that it can potentially be applied in clinical applications. The results indicated the ZnO NPs–modified electrode can detect AA in the concentrations range between 50 and 1,000 μM. The ZnO NPs–modified electrode can detect DA in the concentrations range between 2 and 150 μM. The ZnO NPs–modified electrode can detect UA in the concentrations range between 0.2 and 150 μM. The limits of detections of AA, DA, and UA using ZnO NPs–modified electrode were calculated to be 18.4, 0.75, and 0.11 μM, respectively.

Simultaneous Determination of L-Tyrosine and Caffeine Based on Their Electrocatalytic Oxidation at a 4-tert-butylcalix[6] arene-Modified Carbon Paste Electrode

2013 ◽  
Vol 96 (1) ◽  
pp. 133-141 ◽  
Author(s):  
Ashwini K Srivastava ◽  
Reena R Gaichore
Keyword(s):  
Simultaneous Determination ◽  
Modified Electrode ◽  
Carbon Paste Electrode ◽  
Surface Characterization ◽  
Electrochemical Impedance ◽  
Simultaneous Detection ◽  
Modified Carbon Paste Electrode ◽  
Carbon Paste ◽  
Paste Electrode

Abstract Simultaneous determination of L-tyrosine and caffeine was performed at a carbon paste electrode modified with 4-tert-butylcalix[6]arene and in situ Ni2+ ions. Surface characterization of the electrode was carried out by means of scanning electron microscopy. Electrochemical impedance diagnosis revealed that oxidation of both molecules is kinetically facile on the modified electrode. The electrochemical behavior of both molecules was studied using cyclic voltammetry, and further quantified using differential pulse voltammetry (DPV). The results revealed a high sensitivity for their simultaneous detection. DPV allowed simultaneous detection of L-tyrosine and caffeine in the range of 10–6 to 10–3 M, with LODs of 2.19 × 10–7 and 4.03 × 10–7 M, respectively. The modified electrode was used for individual determination of L-tyrosine and caffeine in various pharmaceutical formulations and simultaneous monitoring in human body fluids.

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