scholarly journals Comprehensive Effects of Near-Infrared Multifunctional Liposomes on Cancer Cells

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1098 ◽  
Author(s):  
Yiqing Deng ◽  
Huaying Huang ◽  
Mengxiao Chen ◽  
Gang Chen ◽  
Wangcai Zou ◽  
...  

Multifunctional theranostic systems are a recent important development of medical research. We combined the characteristics of near-infrared luminescent quantum dots and thermosensitive magnetoliposomes to develop a multifunctional nano-diagnostic material. This system is based on near-infrared magnetic thermosensitive liposomes, which encapsulate drugs and can control drug localization and release. After incubating cancer cells with the liposomes, the state of the cells was analyzed in real time by near-infrared imaging. Cell viability was significantly inhibited by heat treatment or alternating magnetic field treatment, which thus improved the anti-cancer properties of the liposomes. In the future, by combining near-infrared imaging technology and an external high-frequency alternating magnetic field, we could not only detect cancer cells noninvasively but also conduct image-guided treatments for cancer.

Nanoscale ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 415-420 ◽  
Author(s):  
Jitka Slegerova ◽  
Miroslav Hajek ◽  
Ivan Rehor ◽  
Frantisek Sedlak ◽  
Jan Stursa ◽  
...  

Highly effective targeting and background-free, near-infrared imaging of glioma cells was achieved using new nanoparticles based on fluorescent nanodiamonds. The used polymer coating with attached cyclic RGD peptides ensured unusually selective targeting.


2016 ◽  
Vol 824 (2) ◽  
pp. 95 ◽  
Author(s):  
Jungmi Kwon ◽  
Motohide Tamura ◽  
James H. Hough ◽  
Tetsuya Nagata ◽  
Nobuhiko Kusakabe ◽  
...  

2010 ◽  
Vol 716 (1) ◽  
pp. 299-314 ◽  
Author(s):  
Koji Sugitani ◽  
Fumitaka Nakamura ◽  
Motohide Tamura ◽  
Makoto Watanabe ◽  
Ryo Kandori ◽  
...  

2011 ◽  
Vol 734 (1) ◽  
pp. 63 ◽  
Author(s):  
K. Sugitani ◽  
F. Nakamura ◽  
M. Watanabe ◽  
M. Tamura ◽  
S. Nishiyama ◽  
...  

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