scholarly journals Asymmetric Amination of meso-Epoxide with Vegetable Powder as a Low-Toxicity Catalyst

Molecules ◽  
2020 ◽  
Vol 25 (14) ◽  
pp. 3197
Author(s):  
Yuki Takeuchi ◽  
Tatsuhiro Asano ◽  
Kazuya Tsuzaki ◽  
Koichi Wada ◽  
Hiroyuki Kurata

This paper describes the scope and limitation of substrates subjected to asymmetric amination with epoxides catalyzed by a soluble soybean polysaccharide (Soyafibe S-DN), which we recently discovered from the reaction of 1,2-epoxycyclohexane with cyclopropylamine. Various meso-epoxides reacted with various amines afforded the corresponding products with good enantiomeric selectivity. Since it was found that pectin was found to have a catalytic ability after screening commercially available polysaccharides, we studied 33 different vegetable powders having pectic substances, and we found that many vegetable powders showed catalytic ability. These results should guide in using vegetable components as low-toxic catalysts for the production of pharmaceuticals.

2011 ◽  
Vol 221 ◽  
pp. 657-661
Author(s):  
Li Wei Liu ◽  
Wei Min Kang ◽  
Bo Wen Cheng ◽  
Ya Liu

In this paper polylactide (PLA) nanofibers were successfully prepared via electrospinning using low toxic 1,4-dioxane and acetone as co-solvents. The morphology of nanofibers was studied by scanning electron microscopy (SEM) at the different weight ratios of co-solvent, concentrations of spinning solution, electrostatic voltages and collecting distance. Results indicate that the finer and uniform nanofibers were electrospun from the concentration of the spinning solutions at 8 wt.%, 1,4-dioxane and acetone with ratio of 40/60 (w/w), the spinning voltage at 20kV, the collecting distance at 180 mm and the extruding speed at 5 mL/h.


RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87325-87331 ◽  
Author(s):  
Marta Markiewicz ◽  
Joanna Maszkowska ◽  
Véronique Nardello-Rataj ◽  
Stefan Stolte

Ecotoxicity and biodegradability of ILs intended for cellulose processing were tested. Betaine-ester levulinate exhibits low environmental hazard potential (full degradability, low toxicity). Other ILs were partially degradable and moderately toxic.


2019 ◽  
Vol 43 (36) ◽  
pp. 14246-14256 ◽  
Author(s):  
Cristiana Costa ◽  
Joana Farinhas ◽  
Mariana F. G. Velho ◽  
João Avó ◽  
Manuel Matos ◽  
...  

New non-fullerene acceptors were combined with a new polythiophene donor and processed from solvent mixtures of low toxicity in organic photovoltaic cells.


2019 ◽  
Vol 7 (48) ◽  
pp. 27225-27235 ◽  
Author(s):  
Xin Ge ◽  
Xin Qu ◽  
Li He ◽  
Yansen Sun ◽  
Xin Guan ◽  
...  

The 3D low-toxic Cu–Pb binary perovskite films with improved geometric symmetry and typical 2 μm grain size have been prepared, which can achieve a six fold increase in PL intensity and a PCE of 5.1% with suppressed hysteresis for planar solar cells.


Author(s):  
J. H. Luft

Ruthenium red is one of the few completely inorganic dyes used to stain tissues for light microscopy. This novelty is enhanced by ignorance regarding its staining mechanism. However, its continued usefulness in botany for demonstrating pectic substances attests to selectivity of some sort. Whether understood or not, histochemists continue to be grateful for small favors.Ruthenium red can also be used with the electron microscope. If single cells are exposed to ruthenium red solution, sufficient mass can be bound to produce observable density in the electron microscope. Generally, this effect is not useful with solid tissues because the contrast is wasted on the damaged cells at the block surface, with little dye diffusing more than 25-50 μ into the interior. Although these traces of ruthenium red which penetrate between and around cells are visible in the light microscope, they produce negligible contrast in the electron microscope. However, its presence can be amplified by a reaction with osmium tetroxide, probably catalytically, to be easily visible by EM. Now the density is clearly seen to be extracellular and closely associated with collagen fibers (Fig. 1).


2020 ◽  
Vol 31 (2) ◽  
pp. 83-88 ◽  
Author(s):  
Fernando K. Carvalho ◽  
Rodolfo G. Chechetto ◽  
Alisson A. B. Mota ◽  
Ulisses R. Antuniassi

Crop protection on major crops is now required to follow the principles of integrated pest management so the timing and accuracy of any application of a pesticide or biopesticide has to be more precise to minimize adverse effects on non-target species. The development of UAVs (unmanned aerial vehicles) provides a means of providing a more targeted application of the correct dose, especially by using formulations that are more persistent, thus minimizing loss of spray in areas subject to rain. Avoiding use of too high a dosage allows greater survival of natural enemies and reduces the selection pressure for pests becoming resistant to specific modes of action. The downward flow of air from a UAV should also provide better distribution and impaction of droplets within a crop canopy, reduce soil impaction caused by taking heavy loads of spray applied with 200 l ha–1 of water, and allow treatments when fields are too wet to access with ground equipment. In Asia, many smallholder farmers are using a drone in preference to using a knapsack sprayer. According to Matthews, it has been shown that ULV spraying can be effective, but it needs a narrow droplet spectrum with the droplets remaining stable and not shrinking to become too small. Formulation research can reduce the volatility of the spray, hence the success of oil-based sprays. However, instead of petroleum-based oils, there is a chance to develop vegetable oil carriers with micro-sized particle suspensions to deliver low toxicity pesticides in droplets that can be deposited within the crop and not drift beyond the crop boundary. Oil deposits will be less prone to loss after rain so less should be lost in neighbouring ditches and water courses, especially as rainfall patterns are forecast to change. More studies are needed to evaluate the swath for deposition, buffer zones, formulation, nozzle selection, to guide future specific legislation for UAV applications.


2020 ◽  
Author(s):  
Morteza Javadi ◽  
Van A. Ortega ◽  
Alyxandra Thiessen ◽  
Maryam Aghajamali ◽  
Muhammad Amirul Islam ◽  
...  

<p>The design and fabrication of Si-based multi-functional nanomaterials for biological and biomedical applications is an active area of research. The potential benefits of using Si-based nanomaterials are not only due to their size/surface-dependent optical responses but also the high biocompatibility and low-toxicity of silicon itself. Combining these characteristics with the magnetic properties of Fe<sub>3</sub>O<sub>4</sub> nanoparticles (NPs) multiplies the options available for real-world applications. In the current study, biocompatible magnetofluorescent nano-hybrids have been prepared by covalent linking of Si quantum dots to water-dispersible Fe<sub>3</sub>O<sub>4</sub> NPs <i>via</i> dicyclohexylcarbodiimide (DCC) coupling. We explore some of the properties of these magnetofluorescent nano-hybrids as well as evaluate uptake, the potential for cellular toxicity, and the induction of acute cellular oxidative stress in a mast cells-like cell line (RBL-2H3) by heat induction through short-term radio frequency modulation (10 min @ 156 kHz, 500 A). We found that the NPs were internalized readily by the cells and also penetrated the nuclear membrane. Radio frequency activated nano-hybrids also had significantly increased cell death where > 50% of the RBL-2H3 cells were found to be in an apoptotic or necrotic state, and that this was attributable to increased triggering of oxidative cell stress mechanisms. </p>


Author(s):  
L. V. Lukovnikova ◽  
G. I. Sidorin

The article presents the results of a study of the toxicity of fire-resistant turbine oil «Turbomas «, a derivative of diphenyl-(n-tert-butylphenyl phosphate). According to toxicity parameters, «Turbomas» oil is characterized as a low-toxic compound, does not have neuroparalytic action, exhibits mild cumulative properties, does not irritate the skin and mucous membranes, penetrates intact skin,


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