scholarly journals Chiral Recognition for Chromatography and Membrane-Based Separations: Recent Developments and Future Prospects

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1145
Author(s):  
Yuan Zhao ◽  
Xuecheng Zhu ◽  
Wei Jiang ◽  
Huilin Liu ◽  
Baoguo Sun
Keyword(s):  
Rapid Development ◽  
Chiral Molecules ◽  
Future Prospects ◽  
Chiral Drugs ◽  
Recognition Mechanism ◽  
Practical Applications ◽  
Food Industries ◽  
Global Industry ◽  
Endocrine Disrupting ◽  
Recent Developments

With the rapid development of global industry and increasingly frequent product circulation, the separation and detection of chiral drugs/pesticides are becoming increasingly important. The chiral nature of substances can result in harm to the human body, and the selective endocrine-disrupting effect of drug enantiomers is caused by differential enantiospecific binding to receptors. This review is devoted to the specific recognition and resolution of chiral molecules by chromatography and membrane-based enantioseparation techniques. Chromatographic enantiomer separations with chiral stationary phase (CSP)-based columns and membrane-based enantiomer filtration are detailed. In addition, the unique properties of these chiral resolution methods have been summarized for practical applications in the chemistry, environment, biology, medicine, and food industries. We further discussed the recognition mechanism in analytical enantioseparations and analyzed recent developments and future prospects of chromatographic and membrane-based enantioseparations.

Recent Patents on the Angular Contact Ball Bearing of High-Speed Motorized Spindle

2020 ◽  
Vol 13 ◽  
Author(s):  
Yudong Bao ◽  
Linkai Wu ◽  
Yanling Zhao ◽  
Chengyi Pan
Keyword(s):  
High Speed ◽  
Ball Bearing ◽  
Rapid Development ◽  
Ceramic Materials ◽  
Development Trend ◽  
Numerical Control ◽  
Angular Contact Ball Bearing ◽  
Practical Applications ◽  
High Speed Cutting ◽  
Advantages And Disadvantages

Background:: Angular contact ball bearings are the most popular bearing type used in the high speed spindle for machining centers, The performance of the bearing directly affects the machining efficiency of the machine tool, Obtaining a higher value is the direction of its research and development. Objective:: By analyzing the research achievements and patents of electric spindle angular contact bearings, summarizing the development trend provides a reference for the development of electric spindle bearings. Methods:: Through the analysis of the relevant technology of the electric spindle angular contact ball bearing, the advantages and disadvantages of the angular contact ball bearing are introduced, and the research results are combined with the patent analysis. Results:: With the rapid development of high-speed cutting and numerical control technology and the needs of practical applications, the spindle requires higher and higher speeds for bearings. In order to meet the requirements of use, it is necessary to improve the bearing performance by optimizing the structure size and improving the lubrication conditions. Meanwhile, reasonable processing and assembly methods will also have a beneficial effect on bearing performance. Conclusion:: With the continuous deepening of bearing technology research and the use of new structures and ceramic materials has made the bearing's limit speed repeatedly reach new highs. The future development trend of high-speed bearings for electric spindles is environmental protection, intelligence, high speed, high precision and long life.

Assessment and Orff Schulwerk Pedagogy

2019 ◽  
pp. 538-560
Author(s):  
Daniel Johnson
Keyword(s):  
Teacher Educators ◽  
Authentic Assessment ◽  
Research Literature ◽  
National Standards ◽  
International Adoptions ◽  
Practical Applications ◽  
Orff Schulwerk ◽  
Recent Developments ◽  
Based Instruction ◽  
Assessment Strategies

This chapter on assessing student learning and Orff Schulwerk examines the foundations of this approach, its focus on creativity, and practical applications of this pedagogy. By reviewing current research literature and international adoptions of the Schulwerk, the chapter focuses on three assessment-related challenges: a lack of clearly defined teaching practices, a de-emphasis of evaluation in the Orff process, and inherent challenges related to assessing creativity. An examination of professional resource documents and recent developments in national standards provides ways to address each of these assessment challenges in Orff-based instruction. A discussion of curricular levels offers more possibilities for enhancing authentic assessment strategies. Practical recommendations for Orff Schulwerk teachers to improve their assessment protocols and implications for teacher-educators conclude this chapter.

scholarly journals Latest Developments in Insect Sex Pheromone Research and Its Application in Agricultural Pest Management

Insects ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 484
Author(s):  
Syed Arif Hussain Rizvi ◽  
Justin George ◽  
Gadi V. P. Reddy ◽  
Xinnian Zeng ◽  
Angel Guerrero
Keyword(s):  
Sex Pheromone ◽  
Pest Management ◽  
Interdisciplinary Approach ◽  
Pheromone Biosynthesis ◽  
Insect Pheromones ◽  
Agricultural Pest ◽  
Practical Applications ◽  
The Past ◽  
Significant Research ◽  
Recent Developments

Since the first identification of the silkworm moth sex pheromone in 1959, significant research has been reported on identifying and unravelling the sex pheromone mechanisms of hundreds of insect species. In the past two decades, the number of research studies on new insect pheromones, pheromone biosynthesis, mode of action, peripheral olfactory and neural mechanisms, and their practical applications in Integrated Pest Management has increased dramatically. An interdisciplinary approach that uses the advances and new techniques in analytical chemistry, chemical ecology, neurophysiology, genetics, and evolutionary and molecular biology has helped us to better understand the pheromone perception mechanisms and its practical application in agricultural pest management. In this review, we present the most recent developments in pheromone research and its application in the past two decades.

scholarly journals Targeting Genome Stability in Melanoma—A New Approach to an Old Field

2021 ◽  
Vol 22 (7) ◽  
pp. 3485
Author(s):  
Marta Osrodek ◽  
Michal Wozniak
Keyword(s):  
Genome Stability ◽  
Genome Instability ◽  
Checkpoint Inhibitors ◽  
Mapk Pathway ◽  
Rapid Development ◽  
Melanoma Cells ◽  
Old Field ◽  
Number Of Patients ◽  
Recent Developments ◽  
Mapk Inhibitors

Despite recent groundbreaking advances in the treatment of cutaneous melanoma, it remains one of the most treatment-resistant malignancies. Due to resistance to conventional chemotherapy, the therapeutic focus has shifted away from aiming at melanoma genome stability in favor of molecularly targeted therapies. Inhibitors of the RAS/RAF/MEK/ERK (MAPK) pathway significantly slow disease progression. However, long-term clinical benefit is rare due to rapid development of drug resistance. In contrast, immune checkpoint inhibitors provide exceptionally durable responses, but only in a limited number of patients. It has been increasingly recognized that melanoma cells rely on efficient DNA repair for survival upon drug treatment, and that genome instability increases the efficacy of both MAPK inhibitors and immunotherapy. In this review, we discuss recent developments in the field of melanoma research which indicate that targeting genome stability of melanoma cells may serve as a powerful strategy to maximize the efficacy of currently available therapeutics.

scholarly journals Rebuilding the hematopoietic stem cell niche: recent developments and future prospects

2021 ◽  
Author(s):  
Chandralekha Chatterjee ◽  
Peter Schertl ◽  
Miriam Frommer ◽  
Anita Ludwig-Husemann ◽  
Anna Mohra ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Stem Cell Niche ◽  
Future Prospects ◽  
Hematopoietic Stem ◽  
Hematopoietic Stem Cell Niche ◽  
Recent Developments ◽  
Cell Niche

scholarly journals An Identity-Based Blind Signature Scheme Using Lattice with Provable Security

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Quanrun Li ◽  
Chingfang Hsu ◽  
Debiao He ◽  
Kim-Kwang Raymond Choo ◽  
Peng Gong
Keyword(s):  
Quantum Computer ◽  
Rapid Development ◽  
Random Oracle Model ◽  
Random Oracle ◽  
Mean Value ◽  
Blind Signature ◽  
Signature Scheme ◽  
Practical Applications ◽  
Universal Quantum ◽  
Identity Based

With the rapid development of quantum computing and quantum information technology, the universal quantum computer will emerge in the near decades with a very high probability and it could break most of the current public key cryptosystems totally. Due to the ability of withstanding the universal quantum computer’s attack, the lattice-based cryptosystems have received lots of attention from both industry and academia. In this paper, we propose an identity-based blind signature scheme using lattice. We also prove that the proposed scheme is provably secure in the random oracle model. The performance analysis shows that the proposed scheme has less mean value of sampling times and smaller signature size than previous schemes. Thus, the proposed scheme is more suitable for practical applications.

scholarly journals Hierarchical ordering in light-triggered additive manufacturing

2020 ◽  
Vol 11 (46) ◽  
pp. 7316-7329
Author(s):  
Joël Monti ◽  
Eva Blasco
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Future Prospects ◽  
Structural Hierarchy ◽  
Recent Developments ◽  
Hierarchical Ordering

Herein, recent developments in the 3D printing of materials with structural hierarchy and their future prospects are reviewed. It is shown that increasing the extent of ordering, is essential to access novel properties and functionalities.

Recent developments in fabricating drag reduction surfaces covering biological sharkskin morphology

2016 ◽  
Vol 32 (1) ◽  
Author(s):  
Yuehao Luo ◽  
Xia Xu ◽  
Dong Li ◽  
Wen Song
Keyword(s):  
Global Warming ◽  
Drag Reduction ◽  
Rapid Development ◽  
Three Dimensional ◽  
Viscous Drag ◽  
Environment Protection ◽  
Uv Curable ◽  
Recent Developments ◽  
Potential Benefits ◽  
Energy Shortage

AbstractWith the rapid development of science and technology, increasing research interests have been focused on environment protection, global warming, and energy shortage. At present, reducing friction force as much as possible has developed into an urgent issue. Sharkskin effect has the potential ability to lower viscous drag on the fluid-solid interface in turbulence, and therefore, how to fabricate bio-inspired sharkskin surfaces is progressively becoming the hot topic. In this review, various methods of fabricating drag reduction surfaces covering biological sharkskin morphology are illustrated and discussed systematically, mainly involving direct bio-replicated, synthetic fabricating, bio/micro-rolling, enlarged solvent-swelling, drag reduction additive low-releasing, trans-scale enlarged three-dimensional fabricating, flexible printing, large-proportional shrunken bio-replicating, ultraviolet (UV) curable painting, and stretching deformed methods. The overview has the potential benefits in better acquainting with the recent research status of fabricating sharkskin surfaces covering the biological morphology.

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