scholarly journals Dietary Fibres and the Management of Obesity and Metabolic Syndrome: The RESOLVE Study

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2911
Author(s):  
Angelo Tremblay ◽  
Maëlys Clinchamps ◽  
Bruno Pereira ◽  
Daniel Courteix ◽  
Bruno Lesourd ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Dietary Fiber ◽  
Exercise Intervention ◽  
Phase 1 ◽  
Body Weight Loss ◽  
Phase 2 ◽  
Fiber Intake ◽  
Dietary Fiber Intake ◽  
Baseline Values

Objectives: This study was performed to evaluate the long-term maintenance of nutritional changes promoted during an intensive initial intervention to induce body weight loss. The ability of these changes to predict long-term health outcomes was also examined. Methods: Nutritional variables, body composition, and metabolic markers collected in the RESOLVE project were analyzed before and after a 3-week intensive diet–exercise intervention (Phase 1), and during a subsequent supervision under free living conditions, of 12 months (Phase 2). Results: As expected, the macronutrient composition of the diet was modified to promote a negative energy balance during Phase 1. The decrease in carbohydrates imposed during this phase was maintained during Phase 2 whereas the increase in protein intake returned to baseline values at the end of the program. Dietary fiber intake was almost doubled during Phase 1 and remained significantly greater than baseline values throughout Phase 2. Moreover, fiber intake was the only nutritional variable that systematically and significantly predicted variations of health outcomes in the study. Conclusion: The adequacy of dietary fiber intake should be a matter of primary consideration in diet-based weight reduction programs.

scholarly journals Dietary fiber intake, the gut microbiome, and chronic systemic inflammation in a cohort of adult men

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Wenjie Ma ◽  
Long H. Nguyen ◽  
Mingyang Song ◽  
Dong D. Wang ◽  
Eric A. Franzosa ◽  
...  
Keyword(s):  
Dietary Fiber ◽  
Systemic Inflammation ◽  
Gut Microbiome ◽  
Inflammatory Diseases ◽  
Fiber Intake ◽  
Carbohydrate Utilization ◽  
Microbiome Composition ◽  
Reactive Protein ◽  
Dietary Fiber Intake

Abstract Background A higher intake of dietary fiber is associated with a decreased risk of chronic inflammatory diseases such as cardiovascular disease and inflammatory bowel disease. This may function in part due to abrogation of chronic systemic inflammation induced by factors such as dysbiotic gut communities. Data regarding the detailed influences of long-term and recent intake of differing dietary fiber sources on the human gut microbiome are lacking. Methods In a cohort of 307 generally healthy men, we examined gut microbiomes, profiled by shotgun metagenomic and metatranscriptomic sequencing, and long-term and recent dietary fiber intake in relation to plasma levels of C-reactive protein (CRP), an established biomarker for chronic inflammation. Data were analyzed using multivariate linear mixed models. Results We found that inflammation-associated gut microbial configurations corresponded with higher CRP levels. A greater intake of dietary fiber was associated with shifts in gut microbiome composition, particularly Clostridiales, and their potential for carbohydrate utilization via polysaccharide degradation. This was particularly true for fruit fiber sources (i.e., pectin). Most striking, fiber intake was associated with significantly greater CRP reduction in individuals without substantial Prevotella copri carriage in the gut, whereas those with P. copri carriage maintained stable CRP levels regardless of fiber intake. Conclusions Our findings offer human evidence supporting a fiber-gut microbiota interaction, as well as a potential specific mechanism by which gut-mediated systemic inflammation may be mitigated.

scholarly journals Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice

2010 ◽  
Vol 21 (4) ◽  
pp. 278-284 ◽  
Author(s):  
Frank Isken ◽  
Susanne Klaus ◽  
Martin Osterhoff ◽  
Andreas F.H. Pfeiffer ◽  
Martin O. Weickert
Keyword(s):  
Dietary Fiber ◽  
High Fat Diet ◽  
Fiber Intake ◽  
High Fat ◽  
Insoluble Dietary Fiber ◽  
Dietary Fiber Intake ◽  
Diet Induced Obesity

scholarly journals Increased Long-term Dietary Fiber Intake Is Associated With a Decreased Risk of Fecal Incontinence in Older Women

2018 ◽  
Vol 155 (3) ◽  
pp. 661-667.e1 ◽  
Author(s):  
Kyle Staller ◽  
Mingyang Song ◽  
Francine Grodstein ◽  
William E. Whitehead ◽  
Catherine A. Matthews ◽  
...  
Keyword(s):  
Fecal Incontinence ◽  
Older Women ◽  
Dietary Fiber ◽  
Fiber Intake ◽  
Dietary Fiber Intake

Long-term effects of high dietary fiber intake on glucose tolerance and lipid metabolism in GK rats: comparison among barley, rice, and cornstarch

Metabolism ◽  
2003 ◽  
Vol 52 (9) ◽  
pp. 1206-1210 ◽  
Author(s):  
Jue Li ◽  
Takashi Kaneko ◽  
Li-Qiang Qin ◽  
Jing Wang ◽  
Yuan Wang ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Glucose Tolerance ◽  
Dietary Fiber ◽  
Fiber Intake ◽  
Long Term Effects ◽  
Gk Rats ◽  
Dietary Fiber Intake

scholarly journals Dietary fiber intake from fresh and preserved food and risk of nasopharyngeal carcinoma: observational evidence from a Chinese population

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhi-Ming MAI ◽  
Roger Kai-Cheong NGAN ◽  
Dora Lai-Wan KWONG ◽  
Wai-Tong NG ◽  
Kam-Tong Yuen ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Dietary Fiber ◽  
Dose Response ◽  
Sun Exposure ◽  
Fiber Intake ◽  
Total Dietary Fiber ◽  
Dietary Fiber Intake ◽  
Fresh Vegetables ◽  
Incident Cases

Abstract Background The role of dietary fiber intake on risk of nasopharyngeal carcinoma (NPC) remains unclear. We examined the associations of dietary fiber intake on the risk of NPC adjusting for a comprehensive list of potential confounders. Methods Using data from a multicenter case-control study, we included 815 histologically confirmed NPC incident cases and 1502 controls in Hong Kong, China recruited in 2014–2017. Odds ratios (ORs) of NPC (cases vs controls) for dietary fiber intake from different sources at different life periods (age 13–18, age 19–30, and 10 years before recruitment) were evaluated using unconditional logistic regression, adjusting for sex, age, socioeconomic status, smoking and drinking status, occupational hazards, family history of cancer, salted fish, and total energy intake in Model 1, Epstein-Barr virus viral capsid antigen serological status in Model 2, and duration of sun exposure and circulating 25-hydroxyvitamin D in Model 3. Results Higher intake of total dietary fiber 10 years before recruitment was significantly associated with decreased NPC risk, with demonstrable dose-response relationship (P-values for trend = 0.001, 0.020 and 0.024 in Models 1–3, respectively). The adjusted ORs (95% CI) in the highest versus the lowest quartile were 0.51 (0.38–0.69) in Model 1, 0.48 (0.33–0.69) in Model 2, and 0.48 (0.33–0.70) in Model 3. However, the association was less clear after adjustment of other potential confounders (e.g. EBV) in the two younger periods (age of 13–18 and 19–30 years). Risks of NPC were significantly lower for dietary fiber intake from fresh vegetables and fruits and soybean products over all three periods, with dose-response relationships observed in all Models (P-values for trend for age 13–18, age 19–30 and 10 years before recruitment were, respectively, 0.002, 0.009 and 0.001 for Model1; 0.020, 0.031 and 0.003 for Model 2; and 0.022, 0.037 and 0.004 for Model 3). No clear association of NPC risk with dietary fiber intake from preserved vegetables, fruits and condiments was observed. Conclusion Our study has shown the protective role of dietary fiber from fresh food items in NPC risk, but no association for total dietary fiber intake was observed, probably because total intake also included intake of preserved food. Further studies with detailed dietary information and in prospective settings are needed to confirm this finding, and to explore the possible underlying biological mechanisms.

Sign in / Sign up

Export Citation Format

Share Document