scholarly journals Nutritional Biomarkers and Associated Factors in Community-Dwelling Older Adults: Findings from the SHIELD Study

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3329
Author(s):  
Magdalin Cheong ◽  
Samuel Teong Huang Chew ◽  
Jeffery Oliver ◽  
Geraldine Baggs ◽  
Yen Ling Low ◽  
...  
Keyword(s):  
Older Adults ◽  
Nutritional Status ◽  
Vitamin B12 ◽  
Female Gender ◽  
Zinc Level ◽  
Community Dwelling ◽  
Low Level ◽  
Hydroxyvitamin D ◽  
Adverse Health Outcomes ◽  
Community Dwelling Older Adults

Aging is associated with intrinsic and extrinsic changes which affect the nutrient intake and nutritional status of an older individual. Suboptimal nutritional status is linked with adverse health outcomes. There are limited data in this area for community-dwelling older adults who are not at risk of malnutrition. The objective of this study was to describe the nutritional biomarkers in 400 community-dwelling older adults (aged ≥65 years) with normal nutritional status (Malnutrition Universal Screening Test score of 0) in Singapore and to identify factors associated with these biomarkers. The majority of the participants had normal levels of pre-albumin, albumin, total protein, creatinine, zinc, corrected calcium, vitamin B12, ferritin and hemoglobin. Females had significantly higher levels of corrected calcium and vitamin B12 than males, whereas males had significantly higher levels of pre-albumin, albumin, creatinine, serum ferritin, 25-hydroxyvitamin D (25(OH)D) and hemoglobin than females. About half of the participants (52%) had low level of 25(OH)D (<30 μg/L) and 10% had low zinc level (<724 μg/L). Among those with low level of 25(OH)D, 74% had 25(OH)D insufficiency (20–<30 μg/L) and 26% had 25(OH)D deficiency (<20 μg/L). Younger age, female gender, non-Chinese ethnicity and no intake of vitamin D supplement were associated with lower serum 25(OH)D level, whereas higher body mass index (BMI) was associated with low zinc level. These findings highlight the problem of hidden nutritional insufficiencies can be missed in seemingly normal nourished community-dwelling older adults.

scholarly journals LONGITUDINAL CHANGES IN NUTRITIONAL STATUS; SARCOPENIA PROGRESSION IN COMMUNITY-DWELLING OLDER ADULTS

2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 596-596
Author(s):  
S.P. Yew ◽  
W. Lim ◽  
M. Chong ◽  
A. Yeo ◽  
C. Tan ◽  
...  
Keyword(s):  
Older Adults ◽  
Nutritional Status ◽  
Community Dwelling ◽  
Longitudinal Changes ◽  
Community Dwelling Older Adults

scholarly journals Association between the Prognostic Nutritional Index and Dietary Intake in Community-Dwelling Older Adults with Heart Failure: Findings from NHANES III

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2608
Author(s):  
Elisabeth L. P. Sattler ◽  
Yuta Ishikawa ◽  
Rupal Trivedi-Kapoor ◽  
Donglan Zhang ◽  
Arshed A. Quyyumi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Nutritional Status ◽  
Dietary Intake ◽  
Prognostic Nutritional Index ◽  
Red Meat ◽  
Community Dwelling ◽  
Nhanes Iii ◽  
Nutritional Index ◽  
Community Dwelling Older Adults

The objective of this study was to examine the association between nutritional status and dietary intake in community-dwelling older adults with heart failure (HF). A cross-sectional analysis of NHANES III data was conducted. The analytic sample was comprised of n = 445 individuals aged 50+ years with congestive HF (54.4% male, 22.9% non-Hispanic Black, 43.8% low-income). Nutritional status was measured using the Prognostic Nutritional Index (PNI). Participants were classified by PNI quintiles with lower PNI scores indicating lower nutritional status. Participants in quintile 5 showed significantly greater intakes of energy, protein, vegetables, magnesium, zinc, copper, potassium, red meat, saturated fat, and sodium. In multivariate analyses, increased intake of red meat (β = 0.253, p = 0.040) and vegetables (β = 0.255, p = 0.038) was associated with significantly better nutritional status. In the absence of comprehensive nutritional guidance for HF patients, it appears that small increases in energy, protein (red meat), and vegetable consumption are associated with improved nutritional status.

scholarly journals Brain Magnetic Susceptibility is Associated With Slower Gait in Community-Dwelling Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 878-878
Author(s):  
Victoria Poole ◽  
Robert Dawe ◽  
Sue Luergans ◽  
David Bennett ◽  
Aron Buchman ◽  
...  
Keyword(s):  
Older Adults ◽  
Magnetic Susceptibility ◽  
Health Outcomes ◽  
Gait Speed ◽  
Right Hemisphere ◽  
Community Dwelling ◽  
Gaussian Kernel ◽  
Adverse Health ◽  
Adverse Health Outcomes ◽  
Community Dwelling Older Adults

Abstract Age-related slowing of gait is exceedingly common and a robust predictor of various adverse health outcomes in older age. Prior neuroimaging studies have documented diverse non-specific structural brain abnormalities which are related to slow gait; however, the extent to which quantitative susceptibility mapping (QSM), which measures regional magnetic susceptibility in the brain, associates with gait speed remains unexplored. In the current study, 415 non-demented community-dwelling older adults (91 males; 81+/- 7 years) underwent an MRI (Siemens 3T TIM Trio) and in-home motor assessment. Gait speed was measured and averaged across 2 timed 8-ft walks. MR-acquired QSM data were pre-processed, registered to ICBM template, and spatially smoothed with a 5mm FWHM Gaussian kernel. When these maps entered group-level GLMs, voxel-wise associations with gait speed were of interest, after adjusting for demographics. We observed very strong negative associations between gait speed and magnetic susceptibility, such that those with slower gait had higher susceptibility in bilateral inferior frontal, superior temporal, and angular gyri (corrected p&lt;.0005). Robust associations were also observed in the middle frontal, precentral, and postcentral gyri of the right hemisphere. These novel findings suggest that reduced myelination or increased iron accumulation in these brain regions may contribute to impaired gait. Future work will need to determine to what extent these cross-sectional QSM metrics are independent predictors of incident adverse health outcomes when controlling for other common brain imaging abnormalities observed in older adults.

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