scholarly journals Plasma and Urinary Amino Acid-Derived Catabolites as Potential Biomarkers of Protein and Amino Acid Deficiency in Rats

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1567
Author(s):  
Joanna Moro ◽  
Nadezda Khodorova ◽  
Daniel Tomé ◽  
Claire Gaudichon ◽  
Catherine Tardivel ◽  
...  
Keyword(s):  
Amino Acid ◽  
Dietary Intakes ◽  
Analysis Model ◽  
Factorial Method ◽  
New Methods ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Weanling Rats ◽  
Urinary Amino ◽  
One Way Anova

Objective: Dietary intakes must cover protein and essential amino acid (EAA) requirements. For this purpose, different methods have been developed such as the nitrogen balance method, factorial method, or AA tracer studies. However, these methods are either invasive or imprecise, and the Food and Agriculture Organization of the United Nations (FAO, 2013) recommends new methods and, in particular, metabolomics. The aim of this study is to determine total protein/EAA requirement in the plasma and urine of growing rats. Methods: 36 weanling rats were fed with diets containing 3, 5, 8, 12, 15, and 20% protein for 3 weeks. During experimentation, urine was collected using metabolic cages, and blood from the portal vein and vena was taken at the end of the experiment. Metabolomics analyses were performed using LC-MS, and the data were analyzed with a multivariate analysis model, partial least Squares (PLS) regression, and independent component-discriminant analysis (ICDA). Each discriminant metabolite identified by PLS or ICDA was tested by one-way ANOVA to evaluate the effect of diet. Results: PLS and ICDA allowed us to identify discriminating metabolites between different diet groups. Protein deficiency led to an increase in the AA catabolism enzyme systems inducing the production of breakdown metabolites in the plasma and urine. Conclusion: These results indicate that metabolites are specific for the state of EAA deficiency and sufficiency. Some types of biomarkers such as AA degradation metabolites appear to be specific candidates for protein/EAA requirement.

Effect of Galactose Ingestion on the Urinary Amino Acid Excretion in the Rat

1958 ◽  
Vol 193 (1) ◽  
pp. 69-72 ◽  
Author(s):  
L. E. Human ◽  
M. Middleton ◽  
E. Geiger
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Toxic Effects ◽  
Acid Excretion ◽  
Renal Reabsorption ◽  
Weanling Rats ◽  
Urinary Amino

Groups of weanling rats were fed diets containing various levels of galactose or glucose or both. The excretion of amino acids was not affected by the type or quantity of ingested carbohydrate. It seems likely, therefore, that the aminoaciduria observed in galactosemic infants must be due to some cause other than the toxic effects of galactose itself or a competition for the renal reabsorption mechanism.

scholarly journals A Comparison of Protein Digestibility Corrected Amino Acid Score with Digestible Indispensable Amino Acid Score to Evaluate Protein Quality of Raw and Roasted Pistachio Nuts

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 680-680
Author(s):  
Hannah Bailey ◽  
Arianna Carughi ◽  
Hans Stein
Keyword(s):  
Amino Acid ◽  
Protein Quality ◽  
Protein Digestibility ◽  
Growing Pigs ◽  
Protein Source ◽  
Food And Agriculture ◽  
Indispensable Amino Acid ◽  
Food And Agriculture Organization ◽  
Pistachio Nuts ◽  
Amino Acid Score

Abstract Objectives The objectives of this research were to determine the protein digestibility corrected amino acid score (PDCAAS) and the digestible indispensable amino acid score (DIAAS) for raw and roasted American pistachio nuts in growing pigs, and to assess the effect of roasting on these measures of protein quality. Methods Twelve ileal cannulated barrows (body weight: 60.9 ± 3.2 kg) were randomly allotted to a 2-period switch-back design with 3 diets and 4 replicate pigs per period. Roasted pistachio nuts and raw pistachio nuts (American cultivated pistachio nuts) were each added to a single diet as the only protein source, and the third diet was a nitrogen-free diet that was used to measure basal endogenous losses of AA. Experimental periods were 9 d with the initial 5 d for adaptation to the diets. On d 6 and 7, fecal samples were collected, and on d 8 and 9, ileal digesta samples were collected for 9 h each day. The PDCAAS and DIAAS were calculated according to the Food and Agriculture Organization. Results The standardized ileal digestibility (SID) of all indispensable AA, except Arg and Phe, was less (P < 0.05) in roasted than in raw pistachio nuts. Raw pistachio nuts had a PDCAAS of 73 and roasted pistachio nuts had a PDCAAS of 81, calculated for children 2 to 5 yr, and the first limiting AA when compared to human requirements was Thr for both pistachio nuts. The DIAAS calculated for children older than 3 years, adolescents, and adults was 86 and 83 for raw and roasted pistachio nuts, respectively. The limiting AA in both raw and roasted pistachio nuts that determined the DIAAS for this age group was Lys. Conclusions Results of this research illustrate that raw and roasted pistachio nuts can be considered a good quality protein source with DIAAS greater than 75, however, heating conditions associated with roasting may decrease the digestibility of AA in pistachio nuts. Funding Sources The U.S. Department of Agriculture's (USDA) Agricultural Marketing Service. Product was supplied by the American Pistachio Growers.

Dietary Requirements for Proteins and Amino Acids in Human Nutrition

2019 ◽  
Vol 15 (7) ◽  
pp. 638-645 ◽  
Author(s):  
Matej Brestenský ◽  
Soňa Nitrayová ◽  
Peter Patráš ◽  
Jozef Nitray
Keyword(s):  
Amino Acid ◽  
Quality Evaluation ◽  
Protein Quality ◽  
The Body ◽  
Human Nutrition ◽  
Acid Diet ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Dietary Requirements ◽  
Dietary Amino Acid

Background: An optimal dietary Amino Acid (AA) intake is necessary for the growth of body proteins. A new method for protein quality evaluation called Digestible Indispensable AA Score (DIAAS) was established. Despite that the information about dietary AA requirements are available for different stages of life, in practical conditions, most people deal only with the dietary proteins, if ever. Objective: The aim of this mini-review was to analyze the protein quality of protein sources by DIAAS and to find AA and protein dietary requirements in human nutrition. Methods: A literature research was performed using the keyword “amino acid”, “diet”, “nutrition”, “human”, “muscle” and “requirement” individually or all together, in Scopus, Web of Science and Pubmed. Results: The optimum amount of dietary AA is necessary for AA utilization in the body and is limited by AA which is present in the lowest amount; the surplus of other AA is not utilized in the body. Food and Agriculture Organization reported requirements for dietary protein and AA intake for infants, children, however for adults (over 18) for maintenance. Most of the studies which are dealing with the dietary AA requirements in sports nutrition are aimed at the blends of AA and for branched-chain AA. Concerning the protein quality, at this time, there is little information about the protein quality evaluated by DIAAS method. Conclusion: Dietary intake of high-quality protein or a blend of different proteins will provide all AA to the body. However, studies on protein quality evaluation by DIAAS method are necessary to perform.

Food waste and dynamic complex systems: The case of Peru and a solution model proposal Part 1: Peruvian Anchoveta (Engraulis ringens)

2020 ◽  
Author(s):  
Carlos A Almenara
Keyword(s):  
United Nations ◽  
Complex Systems ◽  
Revenue Management ◽  
Food Waste ◽  
Intelligent Systems ◽  
Solution Model ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Engraulis Ringens ◽  
The United Nations

[THE MANUSCRIPT IS A DRAFT] According to the Food and Agriculture Organization of the United Nations (FAO, 2020), food waste and losses comprises nearly 1.3 billion tonnes every year, which equates to around US$ 990 billion worldwide. Ironically, over 820 million people do not have enough food to eat (FAO, 2020). This gap production-consumption puts in evidence the need to reformulate certain practices such as the controversial monocropping (i.e., growing a single crop on the same land on a yearly basis), as well as to improve others such as revenue management through intelligent systems. In this first part of a series of articles, the focus is on the Peruvian anchoveta fish (Engraulis ringens).

To the Empire and Beyond

2018 ◽  
Author(s):  
Gregory A. Barton
Keyword(s):  
Second World War ◽  
World War ◽  
Chemical Fertilizers ◽  
Basic Principles ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Organic Farmers ◽  
Southern Rhodesia ◽  
The Government ◽  
Second World

This chapter traces the expansion of industrial agricultural methods after the Second World War. Western governments and the Food and Agriculture Organization pushed for increased use of chemical fertilizers to aid development and resist Soviet encroachment. Meanwhile small groups of organic farmers and gardeners adopted Howard’s methods in the Anglo-sphere and elsewhere in the world. European movements paralleled these efforts and absorbed the basic principles of the Indore Method. British parliament debated the merits of organic farming, but Howard failed to persuade the government to adopt his policies. Southern Rhodesia, however, did implement his ideas in law. Desiccation theory aided his attempts in South Africa and elsewhere, and Louise Howard, after Albert’s death, kept alive a wide network of activists with her publications.

scholarly journals Ensuring Agricultural Sustainability through Remote Sensing in the Era of Agriculture 5.0

2021 ◽  
Vol 11 (13) ◽  
pp. 5911
Author(s):  
Vanesa Martos ◽  
Ali Ahmad ◽  
Pedro Cartujo ◽  
Javier Ordoñez
Keyword(s):  
Remote Sensing ◽  
Sustainable Agriculture ◽  
Information Acquisition ◽  
Industrial Revolution ◽  
Structural Parameters ◽  
Special Focus ◽  
World Population ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Zero Hunger

Timely and reliable information about crop management, production, and yield is considered of great utility by stakeholders (e.g., national and international authorities, farmers, commercial units, etc.) to ensure food safety and security. By 2050, according to Food and Agriculture Organization (FAO) estimates, around 70% more production of agricultural products will be needed to fulfil the demands of the world population. Likewise, to meet the Sustainable Development Goals (SDGs), especially the second goal of “zero hunger”, potential technologies like remote sensing (RS) need to be efficiently integrated into agriculture. The application of RS is indispensable today for a highly productive and sustainable agriculture. Therefore, the present study draws a general overview of RS technology with a special focus on the principal platforms of this technology, i.e., satellites and remotely piloted aircrafts (RPAs), and the sensors used, in relation to the 5th industrial revolution. Nevertheless, since 1957, RS technology has found applications, through the use of satellite imagery, in agriculture, which was later enriched by the incorporation of remotely piloted aircrafts (RPAs), which is further pushing the boundaries of proficiency through the upgrading of sensors capable of higher spectral, spatial, and temporal resolutions. More prominently, wireless sensor technologies (WST) have streamlined real time information acquisition and programming for respective measures. Improved algorithms and sensors can, not only add significant value to crop data acquisition, but can also devise simulations on yield, harvesting and irrigation periods, metrological data, etc., by making use of cloud computing. The RS technology generates huge sets of data that necessitate the incorporation of artificial intelligence (AI) and big data to extract useful products, thereby augmenting the adeptness and efficiency of agriculture to ensure its sustainability. These technologies have made the orientation of current research towards the estimation of plant physiological traits rather than the structural parameters possible. Futuristic approaches for benefiting from these cutting-edge technologies are discussed in this study. This study can be helpful for researchers, academics, and young students aspiring to play a role in the achievement of sustainable agriculture.

scholarly journals Strengthening implementation of antimicrobial resistance national action plans

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Anderson ◽  
K Schulze ◽  
A Cassini ◽  
D Plauchoras ◽  
E Mossialos
Keyword(s):  
Antimicrobial Resistance ◽  
Policy Design ◽  
Animal Health ◽  
Monitoring And Evaluation ◽  
Basic Structure ◽  
Infection Prevention And Control ◽  
Action Plans ◽  
Governance Framework ◽  
Food And Agriculture ◽  
Food And Agriculture Organization

Abstract Antimicrobial resistance is one of the major challenges of our time. Countries use national action plans as a mechanism to build engagement among stakeholders and coordinate a range of actions across human, animal, and environmental health. However, implementation of recommended policies such as stewardship of antimicrobials, infection prevention and control, and stimulating research and development of novel antimicrobials and alternatives remains inconsistent. Improving the quality of governance within antimicrobial resistance national action plans is an essential step to improving implementation. To date, no systematic approach to governance of national action plans on AMR exists. To address this issue, we aimed to develop the first governance framework to offer guidance for both the development and assessment of national action plans on AMR. We reviewed health system governance framework reviews to inform the basic structure of our framework, international guidance documents from WHO, the Food and Agriculture Organization, the World Organisation for Animal Health, and the European Commission, and sought the input of 25 experts from international organisations, government ministries, policy institutes, and academic institutions to develop and refine our framework. The framework consists of 18 domains with 52 indicators that are contained within three governance areas: policy design, implementation tools, and monitoring and evaluation. Countries must engage with a cyclical process of continuous design, implementation, monitoring and evaluation to achieve these aims.

scholarly journals Analysis of Antioxidant and Antiallergic Active Components Extracted From the Edible Insect Oxya yezoensis

2021 ◽  
Vol 16 (5) ◽  
pp. 1934578X2110233
Author(s):  
Masahiro Saiki ◽  
Naomichi Takemoto ◽  
Maki Nagata ◽  
Masako Matsumoto ◽  
Yhiya Amen ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Unsaturated Fatty Acids ◽  
Soluble Fraction ◽  
Total Phenolic ◽  
Key Factors ◽  
Active Components ◽  
Food And Agriculture ◽  
Food And Agriculture Organization

In recent years, entomophagy has attracted increased attention, as it was recommended as a potential source of food by the Food and Agriculture Organization of the United Nations. In Japan, Oxya yezoensisis one of the most widely eaten insect species, but studies of its functionality as a food are limited. In this study, we reported the optimal characterization of the total phenolic compounds in methanolic extract (OME) and different fractions of OME. Additionally, the antioxidant and antiallergic activities of the OME fractions were evaluated. The results showed that the ethyl acetate-soluble fraction of OME has potential antioxidant activity, whereas the n-hexane-soluble fraction showed the strongest inhibition of β-hexosaminidase, which is one of the key factors in allergic reactions. It was concluded that phenolic compounds might contribute to the antioxidant activity while unsaturated fatty acids contribute to the antiallergy activity.

Food and Agriculture Organization

1952 ◽  
Vol 6 (3) ◽  
pp. 430-432
Keyword(s):  
Director General ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Sixth Session

The sixth session of the Food and Agriculture Organization Conference, held from November 19 to December 7, 1951 in Rome,1 elected Amintore Fanfani (Italy) chairman and reappointed Norris E. Dodd Director-General for an additional two-year period. On November 21, 1951 the conference voted to admit to FAO Argentina by 53 votes to 0, Japan by 47 votes to 0, Nepal by 49 votes to 1, and Laos by 44 votes to 2.

Sign in / Sign up

Export Citation Format

Share Document